pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6121-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of embryonic development GO:0045995 35 11 3,000 1,917E-08 4,683E-05 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 3,000 1,046E-07 1,277E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 1,78E-07 1,45E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 1,993E-07 1,217E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 2,76E-07 1,349E-04 ! activation of caspase activity GO:0006919 95 50 4,000 3,053E-07 1,243E-04 ! nuclear migration GO:0007097 13 6 2,000 4,295E-07 1,499E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 4,295E-07 1,312E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of caspase activity GO:0043280 108 57 4,000 5,94E-07 1,612E-04 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 4,000 5,94E-07 1,451E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 6,001E-07 1,333E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 7,501E-07 1,527E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 7,501E-07 1,41E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 8,407E-07 1,467E-04 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 3,000 8,407E-07 1,369E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 1,198E-06 1,829E-04 ! ER overload response GO:0006983 13 8 2,000 1,198E-06 1,721E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,198E-06 1,626E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,198E-06 1,54E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 1,198E-06 1,463E-04 ! ER-nuclear signaling pathway GO:0006984 52 29 3,000 1,327E-06 1,544E-04 ! negative regulation of protein complex assembly GO:0031333 68 30 3,000 1,528E-06 1,697E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 1,552E-06 1,649E-04 ! negative regulation of kinase activity GO:0033673 145 70 4,000 1,668E-06 1,698E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,793E-06 1,752E-04 ! macrophage differentiation GO:0030225 15 9 2,000 1,793E-06 1,685E-04 ! regulation of caspase activity GO:0043281 136 74 4,000 2,201E-06 1,991E-04 ! negative regulation of transferase activity GO:0051348 155 74 4,000 2,201E-06 1,92E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 2,556E-06 2,153E-04 ! protein sumoylation GO:0016925 17 10 2,000 2,556E-06 2,081E-04 ! regulation of endopeptidase activity GO:0052548 141 77 4,000 2,681E-06 2,113E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 3,507E-06 2,678E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 3,507E-06 2,596E-04 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 22 11 2,000 3,507E-06 2,52E-04 ! regulation of peptidase activity GO:0052547 150 82 4,000 3,662E-06 2,556E-04 ! negative regulation of transport GO:0051051 164 85 4,000 4,373E-06 2,967E-04 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 4,667E-06 3,081E-04 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 33 12 2,000 4,667E-06 3E-04 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 4,667E-06 2,923E-04 GO:0042130|negative regulation of T cell proliferation, ! regulation of intracellular protein transport GO:0033157 86 42 3,000 6,08E-06 3,714E-04 ! regulation of cell adhesion GO:0030155 241 92 4,000 6,454E-06 3,846E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 7,69E-06 4,473E-04 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 7,69E-06 4,369E-04 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 8,365E-06 4,644E-04 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 8,789E-06 4,771E-04 ! pigmentation GO:0043473 103 46 3,000 8,789E-06 4,667E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 8,795E-06 4,571E-04 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 9,593E-06 4,882E-04 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 2,000 1,178E-05 5,874E-04 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 1,178E-05 5,757E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis by extracellular signals GO:0008624 99 50 3,000 1,23E-05 5,89E-04 ! filopodium assembly GO:0046847 42 17 2,000 1,428E-05 6,708E-04 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,428E-05 6,581E-04 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,428E-05 6,459E-04 ! detection of bacterium GO:0016045 22 18 2,000 1,71E-05 7,595E-04 ! microspike assembly GO:0030035 46 18 2,000 1,71E-05 7,459E-04 ! regulation of DNA replication GO:0006275 105 56 3,000 1,936E-05 8,297E-04 ! regulation of intracellular transport GO:0032386 108 57 3,000 2,078E-05 8,751E-04 ! regulation of glucose import GO:0046324 30 20 2,000 2,379E-05 9,851E-04 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 2,379E-05 9,686E-04 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 2,77E-05 1,109E-03 ! negative regulation of intracellular transport GO:0032387 44 21 2,000 2,77E-05 1,091E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 2,77E-05 1,074E-03 ! regulation of protein complex assembly GO:0043254 132 63 3,000 3,093E-05 1,18E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 3,201E-05 1,203E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 3,201E-05 1,185E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 3,201E-05 1,167E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 2,000 3,673E-05 1,32E-03 ! detection of external stimulus GO:0009581 102 68 3,000 4,183E-05 1,481E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 4,189E-05 1,462E-03 ! detection of biotic stimulus GO:0009595 34 24 2,000 4,189E-05 1,441E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 4,751E-05 1,612E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 4,751E-05 1,59E-03 ! regulation of behavior GO:0050795 48 25 2,000 4,751E-05 1,568E-03 ! interaction with host GO:0051701 66 25 2,000 4,751E-05 1,548E-03 ! protein tetramerization GO:0051262 57 25 2,000 4,751E-05 1,527E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 5,36E-05 1,7E-03 ! negative regulation of cell development GO:0010721 83 26 2,000 5,36E-05 1,679E-03 GO:0050768|negative regulation of neurogenesis, ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 5,834E-05 1,804E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 6,017E-05 1,838E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 6,017E-05 1,815E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 6,017E-05 1,793E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 6,726E-05 1,98E-03 ! base-excision repair GO:0006284 41 28 2,000 6,726E-05 1,956E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 6,726E-05 1,933E-03 ! steroid biosynthetic process GO:0006694 146 79 3,000 7,537E-05 2,141E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 7,793E-05 2,188E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 7,793E-05 2,164E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 7,793E-05 2,139E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 7,793E-05 2,115E-03 ! decidualization GO:0046697 11 5 1,000 7,793E-05 2,092E-03 ! mitotic recombination GO:0006312 9 5 1,000 7,793E-05 2,069E-03 ! stem cell division GO:0017145 11 5 1,000 7,793E-05 2,047E-03 GO:0048103|somatic stem cell division, ! positive regulation of phosphorylation GO:0042327 149 81 3,000 8,309E-05 2,16E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 9,138E-05 2,35E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 9,172E-05 2,334E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 1,01E-04 2,544E-03 ! mitochondrion organization GO:0007005 159 87 3,000 1,097E-04 2,736E-03 ! regulation of protein transport GO:0051223 165 87 3,000 1,097E-04 2,708E-03 GO:0070201|regulation of establishment of protein localization, ! leukocyte chemotaxis GO:0030595 55 33 2,000 1,109E-04 2,709E-03 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 2,000 1,109E-04 2,682E-03 ! protein lipoylation GO:0009249 10 6 1,000 1,167E-04 2,795E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 1,167E-04 2,768E-03 GO:0045686|negative regulation of glial cell differentiation, ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,167E-04 2,741E-03 ! maternal placenta development GO:0001893 12 6 1,000 1,167E-04 2,715E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 1,167E-04 2,689E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 1,214E-04 2,771E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 1,214E-04 2,745E-03 ! positive regulation of protein modification process GO:0031401 156 90 3,000 1,252E-04 2,805E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,421E-04 3,156E-03 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,566E-04 3,447E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 1,631E-04 3,557E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,631E-04 3,525E-03 ! protein-cofactor linkage GO:0018065 13 7 1,000 1,631E-04 3,494E-03 ! male sex determination GO:0030238 15 7 1,000 1,631E-04 3,464E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,631E-04 3,434E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,631E-04 3,405E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,631E-04 3,376E-03 ! regulation of protein localization GO:0032880 188 97 3,000 1,672E-04 3,432E-03 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,697E-04 3,455E-03 ! leukocyte differentiation GO:0002521 232 98 3,000 1,739E-04 3,512E-03 ! nucleus organization GO:0006997 73 40 2,000 1,979E-04 3,963E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 2,131E-04 4,233E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,17E-04 4,275E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 2,17E-04 4,241E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 2,17E-04 4,208E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,17E-04 4,174E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 2,17E-04 4,142E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 2,17E-04 4,11E-03 ! response to tumor cell GO:0002347 16 8 1,000 2,17E-04 4,078E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 2,17E-04 4,047E-03 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 2,17E-04 4,016E-03 ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,29E-04 4,207E-03 ! regulation of T cell proliferation GO:0042129 80 43 2,000 2,457E-04 4,48E-03 ! negative regulation of protein complex disassembly GO:0043242 113 44 2,000 2,632E-04 4,762E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 2,632E-04 4,727E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,785E-04 4,966E-03 ! DNA synthesis during DNA repair GO:0000731 18 9 1,000 2,785E-04 4,93E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 2,785E-04 4,895E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 2,785E-04 4,86E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 2,785E-04 4,825E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,785E-04 4,791E-03 ! glycine catabolic process GO:0006546 15 9 1,000 2,785E-04 4,758E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 2,785E-04 4,725E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 3,004E-04 5,061E-03 ! leukocyte migration GO:0050900 75 46 2,000 3,004E-04 5,027E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 3,202E-04 5,322E-03 ! positive regulation of defense response GO:0031349 88 48 2,000 3,409E-04 5,627E-03 ! cellular component disassembly GO:0022411 89 48 2,000 3,409E-04 5,589E-03 ! regulation of inflammatory response GO:0050727 84 48 2,000 3,409E-04 5,552E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 3,475E-04 5,622E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,475E-04 5,585E-03 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 3,475E-04 5,548E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 3,475E-04 5,512E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 3,475E-04 5,477E-03 ! motor axon guidance GO:0008045 22 10 1,000 3,475E-04 5,442E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 3,475E-04 5,407E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 3,475E-04 5,373E-03 GO:0045685|regulation of glial cell differentiation, ! serine family amino acid catabolic process GO:0009071 18 10 1,000 3,475E-04 5,339E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 3,475E-04 5,306E-03 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 18 10 1,000 3,475E-04 5,273E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 3,624E-04 5,465E-03 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 3,624E-04 5,431E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 4,079E-04 6,077E-03 ! negative regulation of immune system process GO:0002683 101 51 2,000 4,079E-04 6,04E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 4,239E-04 6,239E-03 ! detection of mechanical stimulus GO:0050982 22 11 1,000 4,239E-04 6,202E-03 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 4,239E-04 6,165E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 4,239E-04 6,128E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 4,239E-04 6,092E-03 ! DNA methylation GO:0006306 19 11 1,000 4,239E-04 6,056E-03 GO:0006305|DNA alkylation, ! neuroblast proliferation GO:0007405 25 11 1,000 4,239E-04 6,021E-03 ! apical protein localization GO:0045176 18 11 1,000 4,239E-04 5,986E-03 ! regulation of protein complex disassembly GO:0043244 127 52 2,000 4,32E-04 6,066E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 4,57E-04 6,38E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 2,000 4,57E-04 6,344E-03 ! regulation of translational initiation GO:0006446 87 54 2,000 4,829E-04 6,665E-03 ! regulation of muscle contraction GO:0006937 94 54 2,000 4,829E-04 6,628E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 5,078E-04 6,93E-03 ! virus-host interaction GO:0019048 30 12 1,000 5,078E-04 6,892E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 5,078E-04 6,854E-03 ! hippocampus development GO:0021766 29 12 1,000 5,078E-04 6,816E-03 ! entry into host cell GO:0030260 34 12 1,000 5,078E-04 6,779E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! embryonic placenta development GO:0001892 21 12 1,000 5,078E-04 6,742E-03 ! response to UV GO:0009411 120 55 2,000 5,097E-04 6,731E-03 ! negative regulation of cytoskeleton organization GO:0051494 139 56 2,000 5,375E-04 7,06E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 5,662E-04 7,397E-03 ! aging GO:0007568 112 58 2,000 5,959E-04 7,743E-03 ! response to X-ray GO:0010165 28 13 1,000 5,99E-04 7,743E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 5,99E-04 7,702E-03 ! asymmetric protein localization GO:0008105 24 13 1,000 5,99E-04 7,662E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 5,99E-04 7,622E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! establishment of organelle localization GO:0051656 122 59 2,000 6,265E-04 7,93E-03 ! DNA catabolic process GO:0006308 94 60 2,000 6,581E-04 8,288E-03 ! regulation of heart contraction GO:0008016 123 61 2,000 6,908E-04 8,654E-03 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 6,908E-04 8,61E-03 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 6,976E-04 8,65E-03 ! regulation of cellular pH GO:0030641 27 14 1,000 6,976E-04 8,607E-03 ! response to gamma radiation GO:0010332 30 14 1,000 6,976E-04 8,563E-03 ! viral reproductive process GO:0022415 132 62 2,000 7,244E-04 8,849E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 7,948E-04 9,66E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 7,948E-04 9,613E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 8,034E-04 9,668E-03 ! regulation of mRNA processing GO:0050684 26 15 1,000 8,034E-04 9,621E-03 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 8,034E-04 9,574E-03 ! G1/S transition checkpoint GO:0031575 37 15 1,000 8,034E-04 9,528E-03 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 8,694E-04 0,0102607 ! negative regulation of cell growth GO:0030308 142 67 2,000 9,083E-04 0,01066831 ! myeloid cell differentiation GO:0030099 126 67 2,000 9,083E-04 0,01061726 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 9,165E-04 0,01066176 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 9,165E-04 0,01061123 ! viral reproduction GO:0016032 142 68 2,000 9,483E-04 0,01092787 ! cell projection assembly GO:0030031 138 68 2,000 9,483E-04 0,01087656 ! negative regulation of cell size GO:0045792 144 69 2,000 9,894E-04 0,01129482 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 9,894E-04 0,01124229 ! regulation of survival gene product expression GO:0045884 38 17 1,000 1,037E-03 0,01172614 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 1,037E-03 0,01167211 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 1,037E-03 0,01161856 GO:0031114|regulation of microtubule depolymerization, ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 1,037E-03 0,01156551 ! cell cycle checkpoint GO:0000075 145 71 2,000 1,075E-03 0,01193651 ! limbic system development GO:0021761 40 18 1,000 1,164E-03 0,01286983 ! glycine metabolic process GO:0006544 30 18 1,000 1,164E-03 0,01281185 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 1,164E-03 0,0127544 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,164E-03 0,01269746 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 1,164E-03 0,01264103 ! organelle localization GO:0051640 155 74 2,000 1,212E-03 0,01309861 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 1,26E-03 0,0135567 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,299E-03 0,01391677 ! pigmentation during development GO:0048066 42 19 1,000 1,299E-03 0,013856 ! neuromuscular junction development GO:0007528 43 19 1,000 1,299E-03 0,01379575 ! cellular pigmentation GO:0033059 37 19 1,000 1,299E-03 0,01373603 ! regulation of catabolic process GO:0009894 173 77 2,000 1,359E-03 0,01431123 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,44E-03 0,01510354 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 1,44E-03 0,01503899 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,44E-03 0,01497499 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 1,44E-03 0,01491154 ! cellular response to unfolded protein GO:0034620 35 20 1,000 1,44E-03 0,01484862 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,44E-03 0,01478623 ! negative regulation of translation GO:0017148 32 20 1,000 1,44E-03 0,01472437 ! protein oligomerization GO:0051259 149 79 2,000 1,463E-03 0,01489485 ! negative regulation of organelle organization GO:0010639 181 80 2,000 1,517E-03 0,0153797 ! lipid phosphorylation GO:0046834 43 21 1,000 1,589E-03 0,01604312 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 1,589E-03 0,0159771 ! collagen catabolic process GO:0030574 29 21 1,000 1,589E-03 0,01591162 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,589E-03 0,01584667 ! protein import into nucleus GO:0006606 174 82 2,000 1,629E-03 0,01617496 ! response to drug GO:0042493 149 83 2,000 1,686E-03 0,01667969 ! nuclear import GO:0051170 177 83 2,000 1,686E-03 0,01661243 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 1,745E-03 0,01711992 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,745E-03 0,01705144 ! cellular response to starvation GO:0009267 37 22 1,000 1,745E-03 0,0169835 ! cell aging GO:0007569 48 22 1,000 1,745E-03 0,01691611 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,745E-03 0,01684925 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,745E-03 0,01678291 ! negative regulation of growth GO:0045926 168 85 2,000 1,806E-03 0,01729741 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 1,806E-03 0,01722984 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,908E-03 0,01813346 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 1,908E-03 0,01806318 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 1,908E-03 0,01799344 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 1,908E-03 0,01792423 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 1,908E-03 0,01785556 ! DNA modification GO:0006304 36 23 1,000 1,908E-03 0,0177874 ! protein localization in nucleus GO:0034504 192 89 2,000 2,059E-03 0,01912743 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 2,077E-03 0,0192222 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,077E-03 0,01914966 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 2,077E-03 0,01907767 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 2,077E-03 0,01900622 ! barbed-end actin filament capping GO:0051016 58 24 1,000 2,077E-03 0,0189353 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 1,000 2,077E-03 0,01886491 ! pallium development GO:0021543 56 24 1,000 2,077E-03 0,01879504 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 2,077E-03 0,01872568 ! regulation of cell cycle process GO:0010564 161 90 2,000 2,126E-03 0,01909351 ! vasculogenesis GO:0001570 49 25 1,000 2,254E-03 0,02016792 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 2,254E-03 0,02009431 ! negative regulation of DNA replication GO:0008156 45 25 1,000 2,254E-03 0,02002124 ! myelination GO:0042552 50 26 1,000 2,437E-03 0,02157156 ! initiation of viral infection GO:0019059 60 26 1,000 2,437E-03 0,02149369 ! blastocyst development GO:0001824 50 26 1,000 2,437E-03 0,02141637 ! telomere organization GO:0032200 46 26 1,000 2,437E-03 0,02133961 GO:0000723|telomere maintenance, ! regulation of defense response GO:0031347 171 95 2,000 2,479E-03 0,02163282 ! regulation of T cell activation GO:0050863 175 96 2,000 2,554E-03 0,02220613 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 2,627E-03 0,0227599 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 2,627E-03 0,02267947 ! mitochondrial membrane organization GO:0007006 60 27 1,000 2,627E-03 0,02259962 ! multicellular organismal catabolic process GO:0044243 38 27 1,000 2,627E-03 0,02252032 ! response to starvation GO:0042594 47 27 1,000 2,627E-03 0,02244158 ! cellular response to oxidative stress GO:0034599 43 27 1,000 2,627E-03 0,02236338 ! regulation of chromosome organization GO:0033044 49 27 1,000 2,627E-03 0,02228573 ! cellular response to nutrient levels GO:0031669 45 27 1,000 2,627E-03 0,02220862 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,824E-03 0,02379092 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,824E-03 0,02370916 ! protein amino acid acylation GO:0043543 59 28 1,000 2,824E-03 0,02362797 ! dendrite development GO:0016358 67 28 1,000 2,824E-03 0,02354733 ! fat cell differentiation GO:0045444 57 28 1,000 2,824E-03 0,02346723 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 2,824E-03 0,02338768 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 3,028E-03 0,02498947 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 3,028E-03 0,02490533 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 3,238E-03 0,02654613 ! complement activation, classical pathway GO:0006958 51 30 1,000 3,238E-03 0,02645735 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 3,238E-03 0,02636916 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 3,238E-03 0,02628155 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 3,238E-03 0,02619453 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 3,238E-03 0,02610808 ! iron ion homeostasis GO:0055072 60 31 1,000 3,455E-03 0,027766 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 3,455E-03 0,02767496 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 3,455E-03 0,02758452 ! ensheathment of neurons GO:0007272 64 31 1,000 3,455E-03 0,02749467 GO:0008366|axon ensheathment, ! collagen metabolic process GO:0032963 49 32 1,000 3,679E-03 0,02917902 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 3,679E-03 0,02908459 ! response to mechanical stimulus GO:0009612 60 32 1,000 3,679E-03 0,02899077 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 3,679E-03 0,02889755 ! peripheral nervous system development GO:0007422 68 32 1,000 3,679E-03 0,02880493 ! regulation of pH GO:0006885 56 33 1,000 3,909E-03 0,03050952 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 3,909E-03 0,03041235 ! response to ionizing radiation GO:0010212 74 33 1,000 3,909E-03 0,0303158 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 4,146E-03 0,03204997 ! DNA damage checkpoint GO:0000077 78 35 1,000 4,389E-03 0,0338233 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 4,389E-03 0,03371693 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 4,389E-03 0,03361124 ! telencephalon development GO:0021537 81 35 1,000 4,389E-03 0,0335062 ! placenta development GO:0001890 53 35 1,000 4,389E-03 0,03340182 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 4,639E-03 0,03519244 ! negative regulation of DNA binding GO:0043392 67 36 1,000 4,639E-03 0,03508349 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 4,639E-03 0,03497521 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 4,895E-03 0,03679275 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 4,895E-03 0,03667989 ! regulation of microtubule-based process GO:0032886 86 37 1,000 4,895E-03 0,03656772 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 5,157E-03 0,03841137 ! DNA integrity checkpoint GO:0031570 82 38 1,000 5,157E-03 0,03829461 ! regulation of protein stability GO:0031647 77 38 1,000 5,157E-03 0,03817857 ! glycogen metabolic process GO:0005977 63 38 1,000 5,157E-03 0,03806323 ! negative regulation of binding GO:0051100 71 39 1,000 5,426E-03 0,03992688 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 5,426E-03 0,03980698 ! carbohydrate homeostasis GO:0033500 59 39 1,000 5,426E-03 0,0396878 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 64 39 1,000 5,426E-03 0,03956933 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 5,701E-03 0,04145222 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 5,701E-03 0,04132922 ! regulation of action potential in neuron GO:0019228 80 40 1,000 5,701E-03 0,04120694 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 5,983E-03 0,04311357 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 5,983E-03 0,04298677 ! ear morphogenesis GO:0042471 64 42 1,000 6,27E-03 0,0449217 ! T cell differentiation GO:0030217 93 42 1,000 6,27E-03 0,04479035 ! response to reactive oxygen species GO:0000302 75 44 1,000 6,864E-03 0,04888999 ! energy reserve metabolic process GO:0006112 76 44 1,000 6,864E-03 0,04874787 ! double-strand break repair GO:0006302 85 44 1,000 6,864E-03 0,04860657 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 7,17E-03 0,05062792 ! keratinocyte differentiation GO:0030216 81 45 1,000 7,17E-03 0,05048202 ! biopolymer methylation GO:0043414 91 45 1,000 7,17E-03 0,05033695 ! B cell differentiation GO:0030183 124 45 1,000 7,17E-03 0,05019272 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 7,483E-03 0,05222898 ! negative regulation of cell migration GO:0030336 122 46 1,000 7,483E-03 0,05208017 ! positive regulation of protein transport GO:0051222 80 46 1,000 7,483E-03 0,05193222 ! positive regulation of cell cycle GO:0045787 96 48 1,000 8,125E-03 0,05623291 ! mitochondrial transport GO:0006839 94 48 1,000 8,125E-03 0,05607406 ! methylation GO:0032259 97 48 1,000 8,125E-03 0,0559161 ! response to calcium ion GO:0051592 94 49 1,000 8,456E-03 0,05802594 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 8,456E-03 0,0578634 ! regulation of action potential GO:0001508 102 50 1,000 8,792E-03 0,05999663 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 8,792E-03 0,0598295 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 8,792E-03 0,05966331 ! epidermal cell differentiation GO:0009913 87 50 1,000 8,792E-03 0,05949804 ! viral infectious cycle GO:0019058 104 51 1,000 9,134E-03 0,0616431 ! detection of abiotic stimulus GO:0009582 80 51 1,000 9,134E-03 0,06147328 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 9,482E-03 0,06364059 ! positive regulation of growth GO:0045927 96 53 1,000 9,836E-03 0,06583515 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 9,836E-03 0,06565527 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 9,836E-03 0,06547638 ! synapse organization GO:0050808 102 53 1,000 9,836E-03 0,06529845 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01019594 0,0675032 ! protein amino acid lipidation GO:0006497 109 54 1,000 0,01019594 0,06732075 ! regulation of cell shape GO:0008360 142 54 1,000 0,01019594 0,0671393 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,01056146 0,06935924 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,01056146 0,06917329 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,01056146 0,06898834 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,01093271 0,07122299 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,01093271 0,07103357 ! muscle fiber development GO:0048747 131 57 1,000 0,01130968 0,07328792 ! heart morphogenesis GO:0003007 105 57 1,000 0,01130968 0,07309403 ! regulation of actin filament length GO:0030832 118 58 1,000 0,01169231 0,07536761 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,01169231 0,07516928 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01169231 0,07497198 ! lipoprotein biosynthetic process GO:0042158 115 58 1,000 0,01169231 0,07477572 ! lipid modification GO:0030258 112 60 1,000 0,01247447 0,07956951 ! regulation of cellular component size GO:0032535 125 61 1,000 0,01287391 0,08190357 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,01287391 0,08169083 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,0132789 0,08404234 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,0132789 0,08382518 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,01368938 0,08619371 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01398892 0,08785332 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01398892 0,08762805 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01398892 0,08740394 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01398892 0,08718097 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01398892 0,08695914 ! neuron fate determination GO:0048664 7 5 0,000 0,01398892 0,08673843 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01398892 0,08651884 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01398892 0,08630036 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01398892 0,08608298 ! polyol transport GO:0015791 12 5 0,000 0,01398892 0,08586669 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01398892 0,08565148 ! response to superoxide GO:0000303 10 5 0,000 0,01398892 0,08543735 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01398892 0,08522429 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01398892 0,08501229 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01398892 0,08480134 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01398892 0,08459144 ! female meiosis GO:0007143 10 5 0,000 0,01398892 0,08438257 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01398892 0,08417473 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01398892 0,08396791 ! hypothalamus development GO:0021854 9 5 0,000 0,01398892 0,08376211 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01398892 0,08355731 ! cobalt ion transport GO:0006824 11 5 0,000 0,01398892 0,08335351 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01398892 0,08315071 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01398892 0,08294889 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01398892 0,08274804 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01398892 0,08254817 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01398892 0,08234926 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01398892 0,0821513 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01398892 0,0819543 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01398892 0,08175823 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01398892 0,08156311 ! transposition GO:0032196 9 5 0,000 0,01398892 0,08136891 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01398892 0,08117563 ! negative chemotaxis GO:0050919 16 5 0,000 0,01398892 0,08098327 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01398892 0,08079182 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01398892 0,08060128 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01398892 0,08041163 ! behavioral response to pain GO:0048266 10 5 0,000 0,01398892 0,08022287 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01398892 0,08003499 ! Notch receptor processing GO:0007220 11 5 0,000 0,01398892 0,07984799 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01398892 0,07966187 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01398892 0,07947661 ! micturition GO:0060073 9 5 0,000 0,01398892 0,07929221 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01398892 0,07910866 ! copulation GO:0007620 9 5 0,000 0,01398892 0,07892596 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01398892 0,0787441 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01398892 0,07856308 ! bioluminescence GO:0008218 9 5 0,000 0,01398892 0,07838289 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01398892 0,07820353 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01398892 0,07802498 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01398892 0,07784725 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01398892 0,07767032 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01398892 0,0774942 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01398892 0,07731887 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01398892 0,07714434 ! grooming behavior GO:0007625 6 5 0,000 0,01398892 0,07697059 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01398892 0,07679762 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01398892 0,07662543 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01398892 0,07645401 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01398892 0,07628335 ! response to protozoan GO:0001562 13 5 0,000 0,01398892 0,07611345 ! lymph vessel development GO:0001945 10 5 0,000 0,01398892 0,07594431 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01398892 0,07577592 ! endochondral ossification GO:0001958 17 5 0,000 0,01398892 0,07560828 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01398892 0,07544137 ! single strand break repair GO:0000012 8 5 0,000 0,01398892 0,0752752 ! parathyroid gland development GO:0060017 14 5 0,000 0,01398892 0,07510976 ! anagen GO:0042640 7 5 0,000 0,01398892 0,07494505 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01398892 0,07478105 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01398892 0,07461778 ! cytokine secretion GO:0050663 15 5 0,000 0,01398892 0,07445521 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01398892 0,07429335 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01398892 0,07413219 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01398892 0,07397173 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01398892 0,07381197 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01398892 0,07365289 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01398892 0,0734945 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01398892 0,07333678 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01398892 0,07317975 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01398892 0,07302338 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01398892 0,07286768 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01398892 0,07271264 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01398892 0,07255826 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01398892 0,07240454 ! microvillus organization GO:0032528 8 5 0,000 0,01398892 0,07225146 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01398892 0,07209903 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01398892 0,07194724 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01398892 0,07179609 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01398892 0,07164558 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01398892 0,07149569 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01398892 0,07134643 ! polyol catabolic process GO:0046174 9 5 0,000 0,01398892 0,07119779 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01398892 0,07104977 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01398892 0,07090237 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01398892 0,07075557 ! muscle cell migration GO:0014812 8 5 0,000 0,01398892 0,07060938 ! mitochondrial fission GO:0000266 8 5 0,000 0,01398892 0,0704638 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01398892 0,07031881 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01398892 0,07017442 ! mRNA transcription GO:0009299 10 5 0,000 0,01398892 0,07003062 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01398892 0,06988741 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01398892 0,06974478 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01398892 0,06960273 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01398892 0,06946126 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01398892 0,06932037 ! monocyte activation GO:0042117 10 5 0,000 0,01398892 0,06918004 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01398892 0,06904029 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01398892 0,06890109 ! response to food GO:0032094 6 5 0,000 0,01398892 0,06876246 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01398892 0,06862438 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01398892 0,06848686 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01398892 0,06834988 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01398892 0,06821346 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01398892 0,06807757 ! forebrain neuron development GO:0021884 13 5 0,000 0,01398892 0,06794223 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01398892 0,06780742 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01398892 0,06767315 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01398892 0,06753941 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01398892 0,0674062 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01398892 0,06727351 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01398892 0,06714134 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01398892 0,06700969 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01398892 0,06687855 ! lipid glycosylation GO:0030259 7 5 0,000 0,01398892 0,06674793 ! nucleobase transport GO:0015851 6 5 0,000 0,01398892 0,06661782 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01398892 0,06648821 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01398892 0,06635911 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01398892 0,06623051 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01398892 0,0661024 ! basic amino acid transport GO:0015802 12 5 0,000 0,01398892 0,06597479 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01398892 0,06584767 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01398892 0,06572104 ! actin nucleation GO:0045010 11 5 0,000 0,01398892 0,0655949 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01398892 0,06546924 ! depurination GO:0045007 5 5 0,000 0,01398892 0,06534406 ! depyrimidination GO:0045008 10 5 0,000 0,01398892 0,06521935 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01398892 0,06509513 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01398892 0,06497137 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01398892 0,06484809 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01398892 0,06472527 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01398892 0,06460291 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01398892 0,06448102 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01398892 0,06435959 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01398892 0,06423861 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01398892 0,06411809 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01398892 0,06399802 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01398892 0,06387839 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01398892 0,06375922 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01398892 0,06364049 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01398892 0,0635222 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01398892 0,06340434 ! response to arsenic GO:0046685 11 5 0,000 0,01398892 0,06328693 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01398892 0,06316995 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01398892 0,0630534 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01398892 0,06293728 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01398892 0,06282158 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01398892 0,06270631 ! response to mercury ion GO:0046689 8 5 0,000 0,01398892 0,06259147 ! response to cadmium ion GO:0046686 7 5 0,000 0,01398892 0,06247704 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01398892 0,06236303 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01398892 0,06224944 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01398892 0,06213626 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01398892 0,06202349 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01398892 0,06191113 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01398892 0,06179917 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01398892 0,06168762 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01398892 0,06157647 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01398892 0,06146572 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01398892 0,06135537 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01398892 0,06124541 ! embryonic cleavage GO:0040016 6 5 0,000 0,01398892 0,06113585 ! peroxisome fission GO:0016559 5 5 0,000 0,01398892 0,06102668 ! histone demethylation GO:0016577 13 5 0,000 0,01398892 0,0609179 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01398892 0,0608095 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01398892 0,06070149 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01398892 0,06059387 ! metaphase plate congression GO:0051310 7 5 0,000 0,01398892 0,06048662 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01398892 0,06037975 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01398892 0,06027326 ! enteric nervous system development GO:0048484 8 5 0,000 0,01398892 0,06016715 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01398892 0,06006141 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01398892 0,05995604 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01398892 0,05985104 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01398892 0,0597464 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01398892 0,05964213 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01398892 0,05953822 ! B cell homeostasis GO:0001782 13 5 0,000 0,01398892 0,05943468 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01398892 0,05933149 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01398892 0,05922867 ! metaphase GO:0051323 11 5 0,000 0,01398892 0,0591262 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01398892 0,05902408 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01398892 0,05892231 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01398892 0,0588209 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01398892 0,05871983 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01398892 0,05861911 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01398892 0,05851873 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01398892 0,0584187 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01398892 0,05831901 ! response to redox state GO:0051775 6 5 0,000 0,01398892 0,05821966 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01398892 0,05812065 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01398892 0,05802197 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01398892 0,05792363 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01398892 0,05782562 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01398892 0,05772794 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01398892 0,05763059 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01398892 0,05753357 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01398892 0,05743688 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01398892 0,05734051 ! striatum development GO:0021756 14 5 0,000 0,01398892 0,05724446 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01398892 0,05714873 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01398892 0,05705332 ! glial cell migration GO:0008347 10 5 0,000 0,01398892 0,05695824 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01398892 0,05686346 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01398892 0,05676901 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01398892 0,05667486 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01398892 0,05658103 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01398892 0,05648751 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01398892 0,05639429 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01398892 0,05630139 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01398892 0,05620878 ! neuroprotection GO:0043526 8 5 0,000 0,01398892 0,05611649 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01398892 0,05602449 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01398892 0,0559328 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01398892 0,05584141 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01398892 0,05575031 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01398892 0,05565951 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01398892 0,05556901 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01398892 0,0554788 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01398892 0,05538888 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01398892 0,05529926 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01398892 0,05520992 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01398892 0,05512087 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01398892 0,05503211 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01398892 0,05494364 ! spindle assembly GO:0051225 6 5 0,000 0,01398892 0,05485544 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01398892 0,05476753 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01398892 0,05467991 ! protein palmitoylation GO:0018345 12 5 0,000 0,01398892 0,05459256 ! drug metabolic process GO:0017144 7 5 0,000 0,01398892 0,05450549 ! phospholipid scrambling GO:0017121 8 5 0,000 0,01398892 0,0544187 ! organ regeneration GO:0031100 7 5 0,000 0,01398892 0,05433218 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01398892 0,05424594 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01398892 0,05415997 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,01410533 0,05452426 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,01452672 0,05606443 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,01452672 0,055976 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 1,000 0,01452672 0,05588785 ! ear development GO:0043583 114 66 1,000 0,01495352 0,05743937 ! activation of MAPK activity GO:0000187 124 67 1,000 0,01538568 0,0590066 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,01582317 0,06058935 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! adaptive immune response GO:0002250 126 68 1,000 0,01582317 0,06049453 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,01626597 0,06209026 ! activation of immune response GO:0002253 120 70 1,000 0,01671404 0,06370109 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,01671404 0,06360187 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01676337 0,06369039 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01676337 0,06359149 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01676337 0,0634929 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01676337 0,06339461 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01676337 0,06329663 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01676337 0,06319895 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01676337 0,06310157 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01676337 0,06300449 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01676337 0,06290771 ! response to oxygen radical GO:0000305 11 6 0,000 0,01676337 0,06281122 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01676337 0,06271503 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01676337 0,06261914 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01676337 0,06252354 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01676337 0,06242823 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01676337 0,06233321 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01676337 0,06223848 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01676337 0,06214403 ! forebrain regionalization GO:0021871 9 6 0,000 0,01676337 0,06204988 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01676337 0,061956 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01676337 0,06186241 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01676337 0,06176911 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01676337 0,06167608 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01676337 0,06158333 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01676337 0,06149087 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01676337 0,06139868 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01676337 0,06130676 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01676337 0,06121512 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01676337 0,06112376 ! malate metabolic process GO:0006108 13 6 0,000 0,01676337 0,06103266 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01676337 0,06094184 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01676337 0,06085129 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01676337 0,06076101 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01676337 0,06067099 ! protein refolding GO:0042026 15 6 0,000 0,01676337 0,06058124 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01676337 0,06049175 ! opsonization GO:0008228 8 6 0,000 0,01676337 0,06040253 ! mating behavior GO:0007617 7 6 0,000 0,01676337 0,06031358 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01676337 0,06022488 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01676337 0,06013644 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01676337 0,06004827 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01676337 0,05996035 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01676337 0,05987269 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01676337 0,05978528 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01676337 0,05969813 ! toxin metabolic process GO:0009404 11 6 0,000 0,01676337 0,05961123 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01676337 0,05952459 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01676337 0,0594382 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01676337 0,05935205 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01676337 0,05926616 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01676337 0,05918052 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01676337 0,05909512 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01676337 0,05900997 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01676337 0,05892506 ! thymic T cell selection GO:0045061 16 6 0,000 0,01676337 0,0588404 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01676337 0,05875598 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01676337 0,0586718 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01676337 0,05858786 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01676337 0,05850417 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01676337 0,05842071 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01676337 0,05833749 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01676337 0,05825451 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01676337 0,05817176 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01676337 0,05808924 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01676337 0,05800697 ! hyperosmotic response GO:0006972 10 6 0,000 0,01676337 0,05792492 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01676337 0,0578431 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01676337 0,05776152 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01676337 0,05768017 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01676337 0,05759904 ! urea metabolic process GO:0019627 7 6 0,000 0,01676337 0,05751814 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01676337 0,05743747 ! neutrophil activation GO:0042119 7 6 0,000 0,01676337 0,05735703 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01676337 0,05727681 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01676337 0,05719681 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01676337 0,05711704 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01676337 0,05703749 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01676337 0,05695816 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01676337 0,05687905 ! neuron apoptosis GO:0051402 15 6 0,000 0,01676337 0,05680016 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01676337 0,05672149 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01676337 0,05664304 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01676337 0,0565648 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01676337 0,05648678 ! carnitine transport GO:0015879 10 6 0,000 0,01676337 0,05640898 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01676337 0,05633139 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01676337 0,05625401 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01676337 0,05617684 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01676337 0,05609989 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01676337 0,05602314 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01676337 0,05594661 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01676337 0,05587028 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01676337 0,05579417 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01676337 0,05571826 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01676337 0,05564255 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01676337 0,05556705 ! neural nucleus development GO:0048857 19 6 0,000 0,01676337 0,05549176 ! response to UV-C GO:0010225 14 6 0,000 0,01676337 0,05541667 ! astrocyte development GO:0014002 16 6 0,000 0,01676337 0,05534178 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01676337 0,0552671 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01676337 0,05519261 ! interaction with symbiont GO:0051702 14 6 0,000 0,01676337 0,05511833 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01676337 0,05504424 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01676337 0,05497036 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01676337 0,05489667 ! response to copper ion GO:0046688 10 6 0,000 0,01676337 0,05482318 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01676337 0,05474989 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01676337 0,05467679 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01676337 0,05460389 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01676337 0,05453118 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01676337 0,05445867 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01676337 0,05438634 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01676337 0,05431421 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01676337 0,05424227 ! hair follicle maturation GO:0048820 8 6 0,000 0,01676337 0,05417053 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01676337 0,05409897 ! Schwann cell development GO:0014044 15 6 0,000 0,01676337 0,0540276 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01676337 0,05395641 ! response to pheromone GO:0019236 6 6 0,000 0,01676337 0,05388542 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01676337 0,05381461 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01676337 0,05374399 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01676337 0,05367355 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01676337 0,0536033 ! subpallium development GO:0021544 15 6 0,000 0,01676337 0,05353323 ! neural tube patterning GO:0021532 8 6 0,000 0,01676337 0,05346334 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01676337 0,05339363 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01676337 0,05332411 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01676337 0,05325477 ! G2 phase GO:0051319 16 6 0,000 0,01676337 0,05318561 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01676337 0,05311662 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01676337 0,05304782 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01676337 0,05297919 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01676337 0,05291075 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01676337 0,05284247 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01676337 0,05277438 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01676337 0,05270646 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01676337 0,05263871 ! receptor internalization GO:0031623 11 6 0,000 0,01676337 0,05257114 ! plasminogen activation GO:0031639 9 6 0,000 0,01676337 0,05250374 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01676337 0,05243651 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01676337 0,05236946 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01676337 0,05230258 ! protein deubiquitination GO:0016579 16 6 0,000 0,01676337 0,05223586 ! protein destabilization GO:0031648 9 6 0,000 0,01676337 0,05216932 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01676337 0,05210295 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01676337 0,05203674 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01676337 0,05197071 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01676337 0,05190484 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01676337 0,05183914 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01676337 0,0517736 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01676337 0,05170823 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01676337 0,05164302 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01676337 0,05157798 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01676337 0,0515131 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01676337 0,05144839 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01676337 0,05138384 ! neural plate development GO:0001840 9 6 0,000 0,01676337 0,05131945 ! catecholamine transport GO:0051937 9 6 0,000 0,01676337 0,05125522 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01676337 0,05119115 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01676337 0,05112724 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01676337 0,05106349 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01676337 0,0509999 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01676337 0,05093646 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01676337 0,05087319 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01676337 0,05081007 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01676337 0,05074711 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01676337 0,0506843 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01676337 0,05062165 GO:0055081|anion homeostasis, ! B cell activation GO:0042113 179 72 1,000 0,01762586 0,05316047 ! humoral immune response GO:0006959 115 73 1,000 0,01808955 0,0544917 ! acute inflammatory response GO:0002526 118 74 1,000 0,01855838 0,05583511 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01903231 0,05719058 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,01903231 0,05712032 ! axon guidance GO:0007411 162 75 1,000 0,01903231 0,05705024 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01951133 0,05841443 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,01951133 0,05834293 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,01951133 0,05827161 ! tRNA transcription GO:0009304 17 7 0,000 0,01953009 0,05825643 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01953009 0,05818538 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01953009 0,05811451 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01953009 0,05804381 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01953009 0,05797328 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01953009 0,05790293 ! sleep GO:0030431 16 7 0,000 0,01953009 0,05783274 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01953009 0,05776273 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01953009 0,05769288 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01953009 0,0576232 ! prostate gland development GO:0030850 14 7 0,000 0,01953009 0,05755369 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01953009 0,05748435 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01953009 0,05741518 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01953009 0,05734617 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01953009 0,05727733 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01953009 0,05720865 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01953009 0,05714013 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01953009 0,05707179 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01953009 0,0570036 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01953009 0,05693558 ! glycolipid transport GO:0046836 11 7 0,000 0,01953009 0,05686771 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01953009 0,05680001 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01953009 0,05673248 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01953009 0,0566651 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01953009 0,05659788 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01953009 0,05653082 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01953009 0,05646392 ! mRNA stabilization GO:0048255 18 7 0,000 0,01953009 0,05639718 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01953009 0,05633059 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01953009 0,05626417 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01953009 0,05619789 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01953009 0,05613178 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01953009 0,05606582 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01953009 0,05600001 ! lipoprotein transport GO:0042953 14 7 0,000 0,01953009 0,05593436 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01953009 0,05586887 ! rhythmic behavior GO:0007622 17 7 0,000 0,01953009 0,05580352 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01953009 0,05573833 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01953009 0,05567329 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01953009 0,05560841 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01953009 0,05554367 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01953009 0,05547908 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01953009 0,05541465 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01953009 0,05535036 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01953009 0,05528623 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01953009 0,05522224 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01953009 0,0551584 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01953009 0,0550947 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01953009 0,05503116 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01953009 0,05496776 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01953009 0,0549045 ! spinal cord patterning GO:0021511 14 7 0,000 0,01953009 0,05484139 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01953009 0,05477843 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01953009 0,05471561 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01953009 0,05465294 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01953009 0,0545904 ! adrenal gland development GO:0030325 17 7 0,000 0,01953009 0,05452801 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01953009 0,05446577 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01953009 0,05440366 ! ovulation GO:0030728 10 7 0,000 0,01953009 0,0543417 ! adenohypophysis development GO:0021984 11 7 0,000 0,01953009 0,05427988 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01953009 0,0542182 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01953009 0,05415665 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01953009 0,05409525 ! microtubule nucleation GO:0007020 21 7 0,000 0,01953009 0,05403399 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01953009 0,05397286 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01953009 0,05391188 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01953009 0,05385103 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01953009 0,05379032 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01953009 0,05372974 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01953009 0,05366931 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01953009 0,053609 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01953009 0,05354884 ! galactose metabolic process GO:0006012 13 7 0,000 0,01953009 0,0534888 ! vesicle fusion GO:0006906 20 7 0,000 0,01953009 0,05342891 ! response to dietary excess GO:0002021 8 7 0,000 0,01953009 0,05336914 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01953009 0,05330951 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01953009 0,05325001 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01953009 0,05319065 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01953009 0,05313142 ! organ growth GO:0035265 15 7 0,000 0,01953009 0,05307232 ! nucleoside transport GO:0015858 11 7 0,000 0,01953009 0,05301335 ! nucleoside salvage GO:0043174 11 7 0,000 0,01953009 0,05295451 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01953009 0,0528958 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01953009 0,05283722 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01953009 0,05277877 ! parturition GO:0007567 16 7 0,000 0,01953009 0,05272046 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01953009 0,05266227 ! rRNA modification GO:0000154 14 7 0,000 0,01953009 0,0526042 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01953009 0,05254627 ! spindle checkpoint GO:0031577 16 7 0,000 0,01953009 0,05248846 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01953009 0,05243078 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01953009 0,05237323 ! monocyte differentiation GO:0030224 16 7 0,000 0,01953009 0,0523158 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01953009 0,0522585 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01953009 0,05220133 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01953009 0,05214428 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01953009 0,05208735 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01953009 0,05203055 ! fibrinolysis GO:0042730 11 7 0,000 0,01953009 0,05197387 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01953009 0,05191731 ! eating behavior GO:0042755 8 7 0,000 0,01953009 0,05186088 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01953009 0,05180457 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01953009 0,05174839 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01953009 0,05169232 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01953009 0,05163638 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01953009 0,05158055 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01953009 0,05152485 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01953009 0,05146927 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01953009 0,05141381 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01953009 0,05135846 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01953009 0,05130324 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01953009 0,05124813 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01953009 0,05119315 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01953009 0,05113828 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01953009 0,05108352 ! histone ubiquitination GO:0016574 9 7 0,000 0,01953009 0,05102889 ! regulation of meiosis GO:0040020 12 7 0,000 0,01953009 0,05097437 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01953009 0,05091997 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01953009 0,05086568 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01953009 0,05081151 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01953009 0,05075746 ! transcription termination GO:0006353 14 7 0,000 0,01953009 0,05070352 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01953009 0,05064969 ! anaphase GO:0051322 18 7 0,000 0,01953009 0,05059598 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01953009 0,05054239 ! axonal fasciculation GO:0007413 19 7 0,000 0,01953009 0,0504889 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01953009 0,05043553 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01953009 0,05038227 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01953009 0,05032913 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01953009 0,05027609 ! diuresis GO:0030146 12 7 0,000 0,01953009 0,05022317 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01953009 0,05017036 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01953009 0,05011766 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01953009 0,05006507 ! antibiotic transport GO:0042891 9 7 0,000 0,01953009 0,05001259 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01953009 0,04996022 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01953009 0,04990796 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01953009 0,04985581 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01953009 0,04980377 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01953009 0,04975184 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01953009 0,04970001 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01953009 0,0496483 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01953009 0,04959669 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01953009 0,04954518 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01953009 0,04949379 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01953009 0,0494425 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01953009 0,04939132 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01953009 0,04934024 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01953009 0,04928927 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01953009 0,0492384 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01953009 0,04918764 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01953009 0,04913698 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01953009 0,04908643 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01953009 0,04903598 ! muscle adaptation GO:0043500 13 7 0,000 0,01953009 0,04898564 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01953009 0,0489354 ! retina homeostasis GO:0001895 12 7 0,000 0,01953009 0,04888526 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01953009 0,04883522 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01953009 0,04878529 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01953009 0,04873546 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01953009 0,04868573 ! amine catabolic process GO:0009310 136 77 1,000 0,01999539 0,04979484 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01999539 0,04974413 ! lipoprotein metabolic process GO:0042157 147 78 1,000 0,02048446 0,050909 ! antigen processing and presentation GO:0019882 117 78 1,000 0,02048446 0,05085726 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,02097852 0,05203099 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,02097852 0,05197822 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,02147753 0,05316069 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,02147753 0,05310688 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,0222891 0,05505791 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,0222891 0,0550023 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,0222891 0,0549468 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,0222891 0,05489141 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0222891 0,05483613 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0222891 0,05478096 ! male meiosis GO:0007140 9 8 0,000 0,0222891 0,05472591 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,0222891 0,05467096 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,0222891 0,05461613 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,0222891 0,0545614 ! meiotic prophase I GO:0007128 14 8 0,000 0,0222891 0,05450678 ! response to zinc ion GO:0010043 12 8 0,000 0,0222891 0,05445228 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0222891 0,05439788 ! oligopeptide transport GO:0006857 16 8 0,000 0,0222891 0,05434359 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,0222891 0,05428941 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,0222891 0,05423534 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,0222891 0,05418137 ! signal peptide processing GO:0006465 12 8 0,000 0,0222891 0,05412751 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,0222891 0,05407376 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,0222891 0,05402012 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0222891 0,05396658 ! succinate metabolic process GO:0006105 17 8 0,000 0,0222891 0,05391315 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,0222891 0,05385982 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,0222891 0,0538066 ! estrogen metabolic process GO:0008210 17 8 0,000 0,0222891 0,05375348 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,0222891 0,05370047 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0222891 0,05364756 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,0222891 0,05359476 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0222891 0,05354206 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0222891 0,05348947 ! reflex GO:0060004 17 8 0,000 0,0222891 0,05343697 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0222891 0,05338459 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,0222891 0,0533323 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,0222891 0,05328011 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0222891 0,05322803 ! pigment granule organization GO:0048753 17 8 0,000 0,0222891 0,05317605 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,0222891 0,05312417 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,0222891 0,0530724 ! astrocyte differentiation GO:0048708 19 8 0,000 0,0222891 0,05302072 ! histidine catabolic process GO:0006548 10 8 0,000 0,0222891 0,05296914 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0222891 0,05291767 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,0222891 0,05286629 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,0222891 0,05281501 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,0222891 0,05276383 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,0222891 0,05271276 ! melanin metabolic process GO:0006582 17 8 0,000 0,0222891 0,05266178 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,0222891 0,0526109 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,0222891 0,05256011 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,0222891 0,05250943 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0222891 0,05245884 ! macrophage activation GO:0042116 13 8 0,000 0,0222891 0,05240835 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0222891 0,05235796 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,0222891 0,05230766 ! purine salvage GO:0043101 12 8 0,000 0,0222891 0,05225746 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,0222891 0,05220736 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0222891 0,05215735 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,0222891 0,05210744 ! osteoblast development GO:0002076 17 8 0,000 0,0222891 0,05205763 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,0222891 0,05200791 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,0222891 0,05195828 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,0222891 0,05190875 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,0222891 0,05185931 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0222891 0,05180997 ! response to UV-B GO:0010224 17 8 0,000 0,0222891 0,05176072 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,0222891 0,05171156 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0222891 0,0516625 ! intermediate filament organization GO:0045109 12 8 0,000 0,0222891 0,05161353 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,0222891 0,05156466 ! cellular extravasation GO:0045123 13 8 0,000 0,0222891 0,05151587 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,0222891 0,05146718 ! response to antibiotic GO:0046677 11 8 0,000 0,0222891 0,05141858 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,0222891 0,05137007 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,0222891 0,05132166 ! DNA topological change GO:0006265 12 8 0,000 0,0222891 0,05127333 ! response to tropane GO:0014073 15 8 0,000 0,0222891 0,0512251 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,0222891 0,05117695 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,0222891 0,0511289 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0222891 0,05108094 ! mast cell activation GO:0045576 14 8 0,000 0,0222891 0,05103306 ! multicellular organismal aging GO:0010259 20 8 0,000 0,0222891 0,05098528 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,0222891 0,05093758 ! gas homeostasis GO:0033483 14 8 0,000 0,0222891 0,05088998 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,0222891 0,05084246 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,0222891 0,05079503 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,0222891 0,0507477 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0222891 0,05070044 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0222891 0,05065328 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0222891 0,05060621 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,0222891 0,05055922 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,0222891 0,05051232 ! intracellular lipid transport GO:0032365 16 8 0,000 0,0222891 0,0504655 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0222891 0,05041878 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,0222891 0,05037213 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,0222891 0,05032558 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0222891 0,05027911 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,0222891 0,05023273 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,0222891 0,05018643 ! hormone catabolic process GO:0042447 17 8 0,000 0,0222891 0,05014022 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,0222891 0,05009409 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,0222891 0,05004805 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,0222891 0,05000209 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,0222891 0,04995622 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0222891 0,04991043 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,0222891 0,04986472 ! adult feeding behavior GO:0008343 10 8 0,000 0,0222891 0,0498191 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,0222891 0,04977356 ! ATP catabolic process GO:0006200 11 8 0,000 0,0222891 0,04972811 ! blastocyst growth GO:0001832 19 8 0,000 0,0222891 0,04968273 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0222891 0,04963745 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,0222891 0,04959224 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0222891 0,04954711 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,0222891 0,04950207 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,0222891 0,04945711 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,0222891 0,04941223 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,0222891 0,04936743 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,0222891 0,04932271 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,0222891 0,04927808 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0222891 0,04923352 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,0222891 0,04918905 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,0222891 0,04914465 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0222891 0,04910034 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,0222891 0,04905611 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,0222891 0,04901195 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0222891 0,04896788 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,0222891 0,04892388 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,0222891 0,04887996 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,0222891 0,04883612 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,02249027 0,04923274 ! response to metal ion GO:0010038 158 84 1,000 0,02352245 0,05144615 ! T cell activation GO:0042110 189 84 1,000 0,02352245 0,05140014 ! regulation of ligase activity GO:0051340 147 84 1,000 0,02352245 0,0513542 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,02404575 0,0524498 ! axon extension GO:0048675 16 9 0,000 0,02504043 0,05457071 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02504043 0,05452207 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02504043 0,05447352 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02504043 0,05442506 GO:0006740|NADPH regeneration, ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02504043 0,05437668 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02504043 0,05432839 ! reproductive behavior GO:0019098 22 9 0,000 0,02504043 0,05428018 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02504043 0,05423206 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02504043 0,05418403 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02504043 0,05413607 ! UTP metabolic process GO:0046051 10 9 0,000 0,02504043 0,05408821 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02504043 0,05404043 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02504043 0,05399273 ! artery development GO:0060840 25 9 0,000 0,02504043 0,05394512 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02504043 0,05389759 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02504043 0,05385014 ! equilibrioception GO:0050957 20 9 0,000 0,02504043 0,05380278 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02504043 0,0537555 ! chemosensory behavior GO:0007635 21 9 0,000 0,02504043 0,05370831 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02504043 0,0536612 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02504043 0,05361417 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02504043 0,05356722 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02504043 0,05352035 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02504043 0,05347357 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02504043 0,05342687 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02504043 0,05338025 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02504043 0,05333371 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02504043 0,05328725 ! protein targeting to ER GO:0045047 25 9 0,000 0,02504043 0,05324087 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02504043 0,05319458 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02504043 0,05314836 ! T cell selection GO:0045058 27 9 0,000 0,02504043 0,05310223 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02504043 0,05305617 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02504043 0,05301019 ! endosome organization GO:0007032 20 9 0,000 0,02504043 0,0529643 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02504043 0,05291848 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02504043 0,05287274 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02504043 0,05282709 ! mannose metabolic process GO:0006013 13 9 0,000 0,02504043 0,05278151 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02504043 0,052736 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02504043 0,05269058 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,02504043 0,05264524 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02504043 0,05259997 ! receptor clustering GO:0043113 20 9 0,000 0,02504043 0,05255478 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02504043 0,05250967 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02504043 0,05246464 ! retinol metabolic process GO:0042572 20 9 0,000 0,02504043 0,05241968 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02504043 0,0523748 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02504043 0,05233 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02504043 0,05228527 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02504043 0,05224062 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02504043 0,05219604 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02504043 0,05215155 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02504043 0,05210712 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02504043 0,05206278 ! response to amine stimulus GO:0014075 13 9 0,000 0,02504043 0,05201851 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02504043 0,05197431 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02504043 0,05193019 ! erythrocyte development GO:0048821 17 9 0,000 0,02504043 0,05188614 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02504043 0,05184217 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02504043 0,05179828 ! renal water homeostasis GO:0003091 15 9 0,000 0,02504043 0,05175445 ! postreplication repair GO:0006301 25 9 0,000 0,02504043 0,05171071 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02504043 0,05166703 ! icosanoid secretion GO:0032309 15 9 0,000 0,02504043 0,05162343 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02504043 0,0515799 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02504043 0,05153645 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02504043 0,05149307 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02504043 0,05144976 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02504043 0,05140652 ! sterol catabolic process GO:0016127 14 9 0,000 0,02504043 0,05136336 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02504043 0,05132027 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02504043 0,05127725 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02504043 0,05123431 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02504043 0,05119143 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02504043 0,05114863 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02504043 0,0511059 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02504043 0,05106324 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02504043 0,05102065 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02504043 0,05097814 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02504043 0,05093569 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02504043 0,05089331 ! purine base metabolic process GO:0006144 25 9 0,000 0,02504043 0,05085101 ! pigment granule transport GO:0051904 17 9 0,000 0,02504043 0,05080877 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02504043 0,05076661 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02504043 0,05072451 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02504043 0,05068249 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02504043 0,05064053 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02504043 0,05059865 ! mitochondrion localization GO:0051646 18 9 0,000 0,02504043 0,05055683 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,02564413 0,05173295 ! regulation of DNA binding GO:0051101 167 89 1,000 0,02618631 0,05278314 ! response to inorganic substance GO:0010035 173 90 1,000 0,02673314 0,05384094 ! response to unfolded protein GO:0006986 139 90 1,000 0,02673314 0,05379659 ! ossification GO:0001503 205 91 1,000 0,02728459 0,05486111 ! gland development GO:0048732 220 91 1,000 0,02728459 0,05481599 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02778409 0,05577364 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02778409 0,05572785 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02778409 0,05568214 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02778409 0,0556365 ! associative learning GO:0008306 21 10 0,000 0,02778409 0,05559093 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,02778409 0,05554544 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02778409 0,05550002 ! phosphate transport GO:0006817 24 10 0,000 0,02778409 0,05545468 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02778409 0,05540941 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02778409 0,05536421 ! CTP metabolic process GO:0046036 11 10 0,000 0,02778409 0,05531909 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,02778409 0,05527404 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02778409 0,05522907 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02778409 0,05518417 ! social behavior GO:0035176 29 10 0,000 0,02778409 0,05513934 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02778409 0,05509458 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02778409 0,0550499 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02778409 0,05500529 ! androgen metabolic process GO:0008209 17 10 0,000 0,02778409 0,05496075 ! phospholipid efflux GO:0033700 19 10 0,000 0,02778409 0,05491628 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02778409 0,05487189 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02778409 0,05482757 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02778409 0,05478331 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02778409 0,05473913 ! lung alveolus development GO:0048286 26 10 0,000 0,02778409 0,05469502 ! pathogenesis GO:0009405 17 10 0,000 0,02778409 0,05465099 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02778409 0,05460702 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02778409 0,05456312 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02778409 0,0545193 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02778409 0,05447554 ! endoderm development GO:0007492 18 10 0,000 0,02778409 0,05443186 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02778409 0,05438824 ! arginine catabolic process GO:0006527 17 10 0,000 0,02778409 0,0543447 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02778409 0,05430122 ! proline metabolic process GO:0006560 13 10 0,000 0,02778409 0,05425781 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02778409 0,05421448 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02778409 0,05417121 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02778409 0,05412801 ! V(D)J recombination GO:0033151 34 10 0,000 0,02778409 0,05408488 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02778409 0,05404182 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02778409 0,05399883 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02778409 0,0539559 ! B cell proliferation GO:0042100 19 10 0,000 0,02778409 0,05391305 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02778409 0,05387026 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02778409 0,05382754 ! multicellular organism growth GO:0035264 19 10 0,000 0,02778409 0,05378489 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02778409 0,0537423 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02778409 0,05369978 ! ruffle organization GO:0031529 17 10 0,000 0,02778409 0,05365733 ! epithelial cell development GO:0002064 21 10 0,000 0,02778409 0,05361495 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02778409 0,05357263 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02778409 0,05353038 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02778409 0,0534882 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02778409 0,05344608 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02778409 0,05340403 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02778409 0,05336205 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,02778409 0,05332013 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02778409 0,05327828 ! brain morphogenesis GO:0048854 23 10 0,000 0,02778409 0,05323649 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02778409 0,05319477 ! segment specification GO:0007379 15 10 0,000 0,02778409 0,05315311 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02778409 0,05311152 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02778409 0,05307 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02778409 0,05302854 ! response to dsRNA GO:0043331 23 10 0,000 0,02778409 0,05298714 ! DNA ligation GO:0006266 18 10 0,000 0,02778409 0,05294581 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02778409 0,05290454 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02778409 0,05286334 ! melanosome localization GO:0032400 16 10 0,000 0,02778409 0,0528222 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02778409 0,05278112 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02778409 0,05274011 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02778409 0,05269917 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02778409 0,05265828 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02778409 0,05261746 ! induction of an organ GO:0001759 17 10 0,000 0,02778409 0,0525767 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02778409 0,05253601 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02778409 0,05249538 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02778409 0,05245481 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02778409 0,05241431 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02778409 0,05237386 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02778409 0,05233348 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02778409 0,05229316 ! salivary gland development GO:0007431 28 10 0,000 0,02778409 0,05225291 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02778409 0,05221271 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02778409 0,05217258 ! midbrain development GO:0030901 14 10 0,000 0,02778409 0,05213251 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02778409 0,0520925 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02778409 0,05205255 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02778409 0,05201266 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02778409 0,05197284 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02778409 0,05193307 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02778409 0,05189337 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02778409 0,05185372 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02778409 0,05181414 ! detection of calcium ion GO:0005513 24 10 0,000 0,02778409 0,05177462 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02778409 0,05173516 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02778409 0,05169575 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02778409 0,05165641 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02778409 0,05161713 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02778409 0,05157791 ! response to nicotine GO:0035094 20 10 0,000 0,02778409 0,05153874 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02778409 0,05149964 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02778409 0,0514606 ! bone development GO:0060348 206 92 1,000 0,02784062 0,05152623 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,0284012 0,05252395 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,02896632 0,05352853 ! female pregnancy GO:0007565 166 94 1,000 0,02896632 0,05348807 ! regulation of membrane potential GO:0042391 179 94 1,000 0,02896632 0,05344767 ! response to protein stimulus GO:0051789 158 96 1,000 0,03011001 0,05551604 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0305201 0,05622972 ! respiratory burst GO:0045730 17 11 0,000 0,0305201 0,05618735 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0305201 0,05614504 ! neuron fate specification GO:0048665 18 11 0,000 0,0305201 0,05610279 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0305201 0,05606061 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0305201 0,05601849 ! thyroid gland development GO:0030878 26 11 0,000 0,0305201 0,05597644 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,0305201 0,05593444 ! synapsis GO:0007129 14 11 0,000 0,0305201 0,05589251 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0305201 0,05585065 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0305201 0,05580884 ! response to pain GO:0048265 27 11 0,000 0,0305201 0,0557671 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0305201 0,05572542 ! blood vessel remodeling GO:0001974 30 11 0,000 0,0305201 0,0556838 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,0305201 0,05564225 ! bone resorption GO:0045453 16 11 0,000 0,0305201 0,05560076 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0305201 0,05555932 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0305201 0,05551795 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0305201 0,05547665 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0305201 0,0554354 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0305201 0,05539421 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0305201 0,05535309 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0305201 0,05531203 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0305201 0,05527103 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0305201 0,05523008 ! UV protection GO:0009650 20 11 0,000 0,0305201 0,0551892 ! adult heart development GO:0007512 16 11 0,000 0,0305201 0,05514838 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0305201 0,05510762 ! macroautophagy GO:0016236 19 11 0,000 0,0305201 0,05506692 ! temperature homeostasis GO:0001659 18 11 0,000 0,0305201 0,05502628 ! behavioral fear response GO:0001662 27 11 0,000 0,0305201 0,0549857 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0305201 0,05494518 ! negative regulation of ossification GO:0030279 27 11 0,000 0,0305201 0,05490472 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0305201 0,05486432 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0305201 0,05482398 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,0305201 0,0547837 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,0305201 0,05474347 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0305201 0,05470331 ! regulation of organ growth GO:0046620 14 11 0,000 0,0305201 0,05466321 ! pigment granule localization GO:0051875 20 11 0,000 0,0305201 0,05462316 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0305201 0,05458317 ! vasoconstriction GO:0042310 20 11 0,000 0,0305201 0,05454324 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0305201 0,05450337 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0305201 0,05446356 ! embryonic axis specification GO:0000578 19 11 0,000 0,0305201 0,05442381 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0305201 0,05438411 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0305201 0,05434447 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0305201 0,05430489 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0305201 0,05426537 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0305201 0,0542259 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0305201 0,05418649 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0305201 0,05414714 ! prophase GO:0051324 17 11 0,000 0,0305201 0,05410785 ! nucleosome positioning GO:0016584 15 11 0,000 0,0305201 0,05406861 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0305201 0,05402943 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0305201 0,05399031 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0305201 0,05395124 ! acid secretion GO:0046717 20 11 0,000 0,0305201 0,05391223 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0305201 0,05387328 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0305201 0,05383438 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,0305201 0,05379554 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0305201 0,05375675 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0305201 0,05371802 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0305201 0,05367935 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,0305201 0,05364073 ! cholesterol efflux GO:0033344 21 11 0,000 0,0305201 0,05360217 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0305201 0,05356366 ! oocyte development GO:0048599 20 11 0,000 0,0305201 0,05352521 ! germ cell migration GO:0008354 26 11 0,000 0,0305201 0,05348681 ! embryonic gut development GO:0048566 19 11 0,000 0,0305201 0,05344847 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0305201 0,05341018 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0305201 0,05337195 ! activation of innate immune response GO:0002218 16 11 0,000 0,0305201 0,05333377 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0305201 0,05329565 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0305201 0,05325758 ! lysogeny GO:0030069 22 11 0,000 0,0305201 0,05321957 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0305201 0,05318161 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,0305201 0,0531437 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0305201 0,05310585 ! transcription initiation GO:0006352 171 97 1,000 0,03068853 0,0533609 ! forebrain development GO:0030900 210 98 1,000 0,03127145 0,05433582 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,03245043 0,05634427 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,03245043 0,05630425 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0332485 0,05764803 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0332485 0,05760715 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,0332485 0,05756632 ! mating GO:0007618 17 12 0,000 0,0332485 0,05752555 ! protein complex disassembly GO:0043241 28 12 0,000 0,0332485 0,05748484 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0332485 0,05744418 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0332485 0,05740359 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0332485 0,05736305 ! T cell proliferation GO:0042098 32 12 0,000 0,0332485 0,05732257 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0332485 0,05728214 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0332485 0,05724177 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0332485 0,05720146 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0332485 0,05716121 ! drug transport GO:0015893 16 12 0,000 0,0332485 0,05712101 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0332485 0,05708087 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0332485 0,05704078 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0332485 0,05700076 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0332485 0,05696078 ! focal adhesion formation GO:0048041 37 12 0,000 0,0332485 0,05692087 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0332485 0,05688101 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0332485 0,0568412 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0332485 0,05680145 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0332485 0,05676176 ! lipid digestion GO:0044241 21 12 0,000 0,0332485 0,05672212 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0332485 0,05668254 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0332485 0,05664301 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0332485 0,05660354 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0332485 0,05656412 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0332485 0,05652476 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0332485 0,05648545 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0332485 0,0564462 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,0332485 0,056407 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0332485 0,05636785 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0332485 0,05632876 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0332485 0,05628973 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0332485 0,05625075 ! cranial nerve development GO:0021545 23 12 0,000 0,0332485 0,05621182 ! fucose catabolic process GO:0019317 25 12 0,000 0,0332485 0,05617294 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0332485 0,05613412 ! histone acetylation GO:0016573 27 12 0,000 0,0332485 0,05609536 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0332485 0,05605664 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0332485 0,05601798 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0332485 0,05597938 ! zymogen activation GO:0031638 18 12 0,000 0,0332485 0,05594082 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0332485 0,05590232 ! T cell homeostasis GO:0043029 28 12 0,000 0,0332485 0,05586388 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0332485 0,05582548 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0332485 0,05578714 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0332485 0,05574885 ! oocyte differentiation GO:0009994 21 12 0,000 0,0332485 0,05571062 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0332485 0,05567243 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0332485 0,0556343 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0332485 0,05559622 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0332485 0,05555819 ! defense response to fungus GO:0050832 15 12 0,000 0,0332485 0,05552022 ! developmental induction GO:0031128 22 12 0,000 0,0332485 0,05548229 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 24 12 0,000 0,0332485 0,05544442 ! response to cold GO:0009409 17 12 0,000 0,0332485 0,0554066 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0332485 0,05536883 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0332485 0,05533112 ! localization within membrane GO:0051668 26 12 0,000 0,0332485 0,05529345 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03596929 0,05977753 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03596929 0,05973689 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03596929 0,05969631 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03596929 0,05965578 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03596929 0,05961531 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03596929 0,05957489 ! peroxisomal transport GO:0043574 28 13 0,000 0,03596929 0,05953453 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03596929 0,05949422 ! cartilage condensation GO:0001502 22 13 0,000 0,03596929 0,05945397 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03596929 0,05941377 ! organelle fusion GO:0048284 36 13 0,000 0,03596929 0,05937363 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03596929 0,05933354 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03596929 0,0592935 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03596929 0,05925352 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03596929 0,05921359 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03596929 0,05917372 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03596929 0,0591339 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03596929 0,05909413 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03596929 0,05905442 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03596929 0,05901475 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03596929 0,05897515 ! methionine metabolic process GO:0006555 31 13 0,000 0,03596929 0,05893559 ! plasma membrane organization GO:0007009 27 13 0,000 0,03596929 0,05889609 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03596929 0,05885664 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03596929 0,05881725 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03596929 0,05877791 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03596929 0,05873862 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,03596929 0,05869938 ! exocrine system development GO:0035272 34 13 0,000 0,03596929 0,05866019 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03596929 0,05862106 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03596929 0,05858198 ! L-glutamate transport GO:0015813 30 13 0,000 0,03596929 0,05854295 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03596929 0,05850397 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03596929 0,05846505 ! protein homotetramerization GO:0051289 24 13 0,000 0,03596929 0,05842618 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03596929 0,05838736 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03596929 0,05834859 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03596929 0,05830987 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03596929 0,0582712 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03596929 0,05823258 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03596929 0,05819402 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,03596929 0,05815551 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03596929 0,05811704 ! histone methylation GO:0016571 29 13 0,000 0,03596929 0,05807863 ! chromatin silencing GO:0006342 29 13 0,000 0,03596929 0,05804027 ! gland morphogenesis GO:0022612 31 13 0,000 0,03596929 0,05800196 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03596929 0,0579637 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03596929 0,05792549 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03596929 0,05788733 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03596929 0,05784922 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03596929 0,05781116 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03596929 0,05777316 ! spleen development GO:0048536 24 13 0,000 0,03596929 0,0577352 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03596929 0,05769729 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03596929 0,05765943 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03596929 0,05762162 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03596929 0,05758386 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03596929 0,05754615 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03596929 0,05750849 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03596929 0,05747088 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03596929 0,05743331 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03596929 0,0573958 ! insulin secretion GO:0030073 24 13 0,000 0,03596929 0,05735834 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03596929 0,05732092 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03596929 0,05728355 ! acrosome reaction GO:0007340 19 13 0,000 0,03596929 0,05724623 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03596929 0,05720896 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03596929 0,05717174 ! rRNA transcription GO:0009303 28 14 0,000 0,0386825 0,06144431 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0386825 0,06140438 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0386825 0,06136451 ! water transport GO:0006833 21 14 0,000 0,0386825 0,06132469 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0386825 0,06128492 ! non-recombinational repair GO:0000726 29 14 0,000 0,0386825 0,0612452 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0386825 0,06120553 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0386825 0,06116592 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0386825 0,06112635 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0386825 0,06108684 ! lipid localization GO:0010876 32 14 0,000 0,0386825 0,06104738 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0386825 0,06100797 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0386825 0,06096861 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0386825 0,0609293 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0386825 0,06089004 ! arginine metabolic process GO:0006525 21 14 0,000 0,0386825 0,06085083 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0386825 0,06081167 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,0386825 0,06077257 ! regulation of heart rate GO:0002027 25 14 0,000 0,0386825 0,06073351 ! fear response GO:0042596 34 14 0,000 0,0386825 0,0606945 ! organic alcohol transport GO:0015850 29 14 0,000 0,0386825 0,06065555 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0386825 0,06061664 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0386825 0,06057778 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0386825 0,06053898 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0386825 0,06050022 ! bone mineralization GO:0030282 18 14 0,000 0,0386825 0,06046151 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0386825 0,06042285 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0386825 0,06038424 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0386825 0,06034568 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0386825 0,06030717 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0386825 0,06026871 ! ribosome assembly GO:0042255 18 14 0,000 0,0386825 0,0602303 ! cerebellum development GO:0021549 23 14 0,000 0,0386825 0,06019194 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,0386825 0,06015362 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0386825 0,06011536 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0386825 0,06007714 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0386825 0,06003897 ! NADP metabolic process GO:0006739 24 14 0,000 0,0386825 0,06000085 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0386825 0,05996278 ! oxygen transport GO:0015671 22 14 0,000 0,0386825 0,05992476 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0386825 0,05988678 ! male genitalia development GO:0030539 26 14 0,000 0,0386825 0,05984886 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0386825 0,05981098 ! regulation of axon extension GO:0030516 43 14 0,000 0,0386825 0,05977315 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0386825 0,05973536 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0386825 0,05969763 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04138815 0,06383286 ! lactation GO:0007595 30 15 0,000 0,04138815 0,06379258 ! reproductive cellular process GO:0048610 22 15 0,000 0,04138815 0,06375236 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04138815 0,06371219 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04138815 0,06367207 ! superoxide anion generation GO:0042554 22 15 0,000 0,04138815 0,063632 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04138815 0,06359198 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,04138815 0,06355201 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04138815 0,06351209 ! copper ion transport GO:0006825 22 15 0,000 0,04138815 0,06347222 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04138815 0,0634324 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04138815 0,06339263 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04138815 0,06335291 ! sulfate transport GO:0008272 27 15 0,000 0,04138815 0,06331324 ! response to cAMP GO:0051591 25 15 0,000 0,04138815 0,06327362 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04138815 0,06323405 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04138815 0,06319453 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04138815 0,06315506 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04138815 0,06311563 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04138815 0,06307626 ! vesicle coating GO:0006901 38 15 0,000 0,04138815 0,06303694 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,04138815 0,06299766 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04138815 0,06295843 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04138815 0,06291926 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04138815 0,06288013 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04138815 0,06284105 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04138815 0,06280202 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04138815 0,06276303 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04138815 0,0627241 ! histone deacetylation GO:0016575 24 15 0,000 0,04138815 0,06268521 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04138815 0,06264637 ! water homeostasis GO:0030104 28 15 0,000 0,04138815 0,06260758 ! cofactor transport GO:0051181 30 15 0,000 0,04138815 0,06256884 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04138815 0,06253015 ! muscle maintenance GO:0046716 26 15 0,000 0,04138815 0,0624915 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04138815 0,0624529 ! intestinal absorption GO:0050892 31 15 0,000 0,04138815 0,06241435 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04138815 0,06237585 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04138815 0,06233739 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04138815 0,06229898 ! cell killing GO:0001906 32 15 0,000 0,04138815 0,06226062 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04138815 0,06222231 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,04138815 0,06218404 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04138815 0,06214582 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04138815 0,06210764 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04138815 0,06206952 ! actin filament polymerization GO:0030041 27 15 0,000 0,04138815 0,06203144 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04138815 0,06199341 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04408626 0,06599432 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04408626 0,06595391 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04408626 0,06591354 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04408626 0,06587323 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04408626 0,06583297 ! bone remodeling GO:0046849 28 16 0,000 0,04408626 0,06579275 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04408626 0,06575258 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04408626 0,06571247 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04408626 0,0656724 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04408626 0,06563238 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04408626 0,06559241 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04408626 0,06555248 ! startle response GO:0001964 28 16 0,000 0,04408626 0,06551261 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04408626 0,06547278 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04408626 0,06543301 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04408626 0,06539328 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04408626 0,0653536 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04408626 0,06531397 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04408626 0,06527438 ! pituitary gland development GO:0021983 30 16 0,000 0,04408626 0,06523485 ! response to osmotic stress GO:0006970 27 16 0,000 0,04408626 0,06519536 ! lysosomal transport GO:0007041 31 16 0,000 0,04408626 0,06515592 ! fructose metabolic process GO:0006000 25 16 0,000 0,04408626 0,06511652 ! L-amino acid transport GO:0015807 33 16 0,000 0,04408626 0,06507718 ! stem cell development GO:0048864 46 16 0,000 0,04408626 0,06503788 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04408626 0,06499863 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04408626 0,06495943 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04408626 0,06492027 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04408626 0,06488116 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04408626 0,0648421 ! axon cargo transport GO:0008088 46 16 0,000 0,04408626 0,06480309 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04408626 0,06476412 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,04408626 0,0647252 ! DNA replication initiation GO:0006270 28 16 0,000 0,04408626 0,06468632 ! neuron recognition GO:0008038 40 16 0,000 0,04408626 0,0646475 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04408626 0,06460872 ! tissue regeneration GO:0042246 27 16 0,000 0,04408626 0,06456998 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04408626 0,06453129 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04408626 0,06449265 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04408626 0,06445406 ! biomineral formation GO:0031214 22 16 0,000 0,04408626 0,06441551 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04408626 0,06437701 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04408626 0,06433855 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04408626 0,06430014 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04408626 0,06426177 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04408626 0,06422345 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04408626 0,06418518 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04408626 0,06414695 ! peptide hormone processing GO:0016486 27 16 0,000 0,04408626 0,06410877 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04677685 0,06798087 ! metencephalon development GO:0022037 32 17 0,000 0,04677685 0,06794046 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04677685 0,06790009 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,04677685 0,06785977 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04677685 0,06781949 ! signal complex assembly GO:0007172 47 17 0,000 0,04677685 0,06777927 ! endothelial cell migration GO:0043542 31 17 0,000 0,04677685 0,06773909 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04677685 0,06769896 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04677685 0,06765888 ! glial cell development GO:0021782 28 17 0,000 0,04677685 0,06761885 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04677685 0,06757886 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04677685 0,06753892 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04677685 0,06749902 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04677685 0,06745918 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04677685 0,06741938 ! myoblast differentiation GO:0045445 50 17 0,000 0,04677685 0,06737963 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04677685 0,06733992 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04677685 0,06730026 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04677685 0,06726065 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04677685 0,06722109 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04677685 0,06718157 ! NAD metabolic process GO:0019674 33 17 0,000 0,04677685 0,0671421 ! membrane budding GO:0006900 42 17 0,000 0,04677685 0,06710267 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04677685 0,06706329 ! regulation of protein binding GO:0043393 33 17 0,000 0,04677685 0,06702396 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04677685 0,06698467 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04677685 0,06694543 ! genitalia development GO:0048806 32 17 0,000 0,04677685 0,06690623 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04677685 0,06686709 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04677685 0,06682798 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04677685 0,06678892 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04677685 0,06674991 ! steroid catabolic process GO:0006706 34 17 0,000 0,04677685 0,06671094 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04677685 0,06667202 ! gas transport GO:0015669 26 17 0,000 0,04677685 0,06663315 ! organic cation transport GO:0015695 32 17 0,000 0,04677685 0,06659432 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04677685 0,06655553 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04677685 0,06651679 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04677685 0,0664781 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04945995 0,07025038 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04945995 0,07020956 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04945995 0,07016879 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04945995 0,07012806 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04945995 0,07008738 ! adult walking behavior GO:0007628 36 18 0,000 0,04945995 0,07004675 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04945995 0,07000617 ! heart looping GO:0001947 34 18 0,000 0,04945995 0,06996563 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04945995 0,06992514 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04945995 0,0698847 ! centrosome cycle GO:0007098 26 18 0,000 0,04945995 0,06984431 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04945995 0,06980396 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04945995 0,06976365 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04945995 0,0697234 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04945995 0,06968319 ! response to retinoic acid GO:0032526 31 18 0,000 0,04945995 0,06964303 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,04945995 0,06960291 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04945995 0,06956284 ! DNA integration GO:0015074 32 18 0,000 0,04945995 0,06952281 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04945995 0,06948283 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04945995 0,0694429 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04945995 0,06940302 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04945995 0,06936317 ! neural crest cell migration GO:0001755 41 18 0,000 0,04945995 0,06932338 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04945995 0,06928363 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04945995 0,06924393 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04945995 0,06920427 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04945995 0,06916465 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04945995 0,06912509 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04945995 0,06908556 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04945995 0,06904609 ! nerve development GO:0021675 34 18 0,000 0,04945995 0,06900665 ! defense response to virus GO:0051607 43 18 0,000 0,04945995 0,06896727 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04945995 0,06892792 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05213556 0,07261527 ! positive regulation of translation GO:0045727 31 19 0,000 0,05213556 0,07257389 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05213556 0,07253257 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,05213556 0,07249128 ! neuron maturation GO:0042551 46 19 0,000 0,05213556 0,07245005 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05213556 0,07240886 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05213556 0,07236772 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05213556 0,07232662 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05213556 0,07228558 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05213556 0,07224457 ! inositol metabolic process GO:0006020 33 19 0,000 0,05213556 0,07220362 ! memory GO:0007613 34 19 0,000 0,05213556 0,07216271 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05213556 0,07212185 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05213556 0,07208103 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,05213556 0,07204026 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05213556 0,07199954 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,05213556 0,07195886 ! cerebral cortex development GO:0021987 40 19 0,000 0,05213556 0,07191823 ! response to vitamin A GO:0033189 32 19 0,000 0,05213556 0,07187764 ! heme metabolic process GO:0042168 40 19 0,000 0,05213556 0,0718371 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05213556 0,07179661 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,05213556 0,07175616 ! response to fungus GO:0009620 26 19 0,000 0,05213556 0,07171576 ! peptide cross-linking GO:0018149 39 19 0,000 0,05213556 0,0716754 ! protein export from nucleus GO:0006611 40 19 0,000 0,05213556 0,07163509 ! heart process GO:0003015 32 19 0,000 0,05213556 0,07159482 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05213556 0,0715546 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05213556 0,07151442 ! visual learning GO:0008542 38 19 0,000 0,05213556 0,07147429 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05213556 0,0714342 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05213556 0,07139416 ! vitamin transport GO:0051180 31 19 0,000 0,05213556 0,07135416 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05213556 0,07131421 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05213556 0,07127431 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05213556 0,07123444 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05213556 0,07119463 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05213556 0,07115485 ! cilium assembly GO:0042384 38 19 0,000 0,05213556 0,07111512 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05213556 0,07107544 ! protein secretion GO:0009306 45 20 0,000 0,05480373 0,07467122 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05480373 0,0746296 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,05480373 0,07458802 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05480373 0,07454649 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,05480373 0,07450501 ! skin development GO:0043588 42 20 0,000 0,05480373 0,07446357 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,05480373 0,07442218 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05480373 0,07438084 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,05480373 0,07433954 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05480373 0,07429828 ! response to vitamin GO:0033273 36 20 0,000 0,05480373 0,07425707 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,05480373 0,07421591 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05480373 0,07417479 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05480373 0,07413372 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05480373 0,0740927 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,05480373 0,07405172 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05480373 0,07401078 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05480373 0,07396989 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 0,05480373 0,07392905 ! body fluid secretion GO:0007589 33 20 0,000 0,05480373 0,07388825 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05480373 0,07384749 ! peptide secretion GO:0002790 38 20 0,000 0,05480373 0,07380678 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05480373 0,07376612 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,05480373 0,0737255 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05480373 0,07368492 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05480373 0,07364439 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05480373 0,07360391 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05480373 0,07356346 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,05480373 0,07352307 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05480373 0,07348271 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05480373 0,0734424 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05480373 0,07340214 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05480373 0,07336192 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05480373 0,07332174 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05480373 0,07328161 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05480373 0,07324152 ! regulation of cell killing GO:0031341 46 21 0,000 0,05746445 0,07675542 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05746445 0,07671347 ! hormone secretion GO:0046879 39 21 0,000 0,05746445 0,07667158 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05746445 0,07662973 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05746445 0,07658792 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05746445 0,07654616 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05746445 0,07650445 ! ovarian follicle development GO:0001541 39 21 0,000 0,05746445 0,07646278 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05746445 0,07642115 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05746445 0,07637957 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05746445 0,07633804 ! plasma membrane fusion GO:0045026 33 21 0,000 0,05746445 0,07629655 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05746445 0,07625511 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05746445 0,07621371 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,05746445 0,07617236 ! sensory perception of pain GO:0019233 33 21 0,000 0,05746445 0,07613105 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05746445 0,07608979 ! diencephalon development GO:0021536 36 21 0,000 0,05746445 0,07604857 ! collagen fibril organization GO:0030199 62 21 0,000 0,05746445 0,07600739 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05746445 0,07596626 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05746445 0,07592518 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,05746445 0,07588414 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05746445 0,07584314 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05746445 0,07580219 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05746445 0,07576128 ! actin filament-based movement GO:0030048 47 21 0,000 0,05746445 0,07572042 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06011776 0,07917396 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,06011776 0,0791313 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06011776 0,07908869 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06011776 0,07904612 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06011776 0,0790036 ! microtubule-based transport GO:0010970 59 22 0,000 0,06011776 0,07896113 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,06011776 0,0789187 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06011776 0,07887631 ! vacuolar transport GO:0007034 41 22 0,000 0,06011776 0,07883397 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06011776 0,07879168 ! fucose metabolic process GO:0006004 44 22 0,000 0,06011776 0,07874943 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06011776 0,07870723 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06011776 0,07866507 ! ureteric bud development GO:0001657 50 22 0,000 0,06011776 0,07862296 ! stem cell differentiation GO:0048863 57 22 0,000 0,06011776 0,0785809 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06011776 0,07853887 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06011776 0,0784969 ! cytolysis GO:0019835 27 22 0,000 0,06011776 0,07845497 ! renal system process GO:0003014 42 22 0,000 0,06011776 0,07841308 ! vasodilation GO:0042311 40 22 0,000 0,06011776 0,07837124 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06011776 0,07832944 ! G1 phase GO:0051318 44 22 0,000 0,06011776 0,07828768 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06011776 0,07824597 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06011776 0,07820431 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06011776 0,07816269 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06011776 0,07812111 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06011776 0,07807958 ! sarcomere organization GO:0045214 32 22 0,000 0,06011776 0,07803809 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,06011776 0,07799665 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06011776 0,07795525 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06011776 0,0779139 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06011776 0,07787258 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06011776 0,07783132 ! gut development GO:0048565 44 22 0,000 0,06011776 0,07779009 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06011776 0,07774891 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,06011776 0,07770777 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06011776 0,07766668 ! protein stabilization GO:0050821 41 22 0,000 0,06011776 0,07762563 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06276368 0,0809993 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06276368 0,08095653 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06276368 0,08091381 ! gluconeogenesis GO:0006094 38 23 0,000 0,06276368 0,08087113 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06276368 0,0808285 ! viral genome replication GO:0019079 44 23 0,000 0,06276368 0,08078592 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06276368 0,08074337 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06276368 0,08070088 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06276368 0,08065843 ! regeneration GO:0031099 42 23 0,000 0,06276368 0,08061602 ! axis specification GO:0009798 43 23 0,000 0,06276368 0,08057366 ! visual behavior GO:0007632 46 23 0,000 0,06276368 0,08053134 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06276368 0,08048906 ! response to ethanol GO:0045471 47 23 0,000 0,06276368 0,08044683 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06276368 0,08040465 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06276368 0,08036251 ! peroxisome organization GO:0007031 43 23 0,000 0,06276368 0,08032041 ! lysosome organization GO:0007040 47 23 0,000 0,06276368 0,08027836 ! vesicle targeting GO:0006903 49 23 0,000 0,06276368 0,08023635 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06276368 0,08019439 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06276368 0,08015247 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06276368 0,08011059 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06276368 0,08006876 ! fatty acid transport GO:0015908 47 23 0,000 0,06276368 0,08002697 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,06276368 0,07998522 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06276368 0,07994352 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06276368 0,07990186 ! hormone transport GO:0009914 41 23 0,000 0,06276368 0,07986024 ! cell-cell recognition GO:0009988 28 23 0,000 0,06276368 0,07981867 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06276368 0,07977714 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06276368 0,07973566 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06276368 0,07969421 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06540222 0,08300136 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06540222 0,08295827 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06540222 0,08291522 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06540222 0,08287221 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06540222 0,08282925 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06540222 0,08278633 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06540222 0,08274346 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06540222 0,08270063 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06540222 0,08265785 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06540222 0,08261511 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06540222 0,08257242 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,06540222 0,08252976 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06540222 0,08248716 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06540222 0,08244459 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06540222 0,08240208 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06540222 0,0823596 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06540222 0,08231717 ! membrane depolarization GO:0051899 45 24 0,000 0,06540222 0,08227478 ! oogenesis GO:0048477 44 24 0,000 0,06540222 0,08223244 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06540222 0,08219014 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,06540222 0,08214788 ! platelet activation GO:0030168 41 24 0,000 0,06540222 0,08210566 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06540222 0,08206349 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06540222 0,08202137 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06540222 0,08197928 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06540222 0,08193724 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06540222 0,08189525 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,06540222 0,08185329 ! regulation of amine transport GO:0051952 41 24 0,000 0,06540222 0,08181138 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,06803341 0,08505917 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,06803341 0,08501566 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06803341 0,0849722 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06803341 0,08492878 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06803341 0,0848854 ! phototransduction GO:0007602 37 25 0,000 0,06803341 0,08484207 ! keratinization GO:0031424 37 25 0,000 0,06803341 0,08479878 ! vacuole organization GO:0007033 49 25 0,000 0,06803341 0,08475554 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06803341 0,08471234 ! receptor metabolic process GO:0043112 53 25 0,000 0,06803341 0,08466919 ! chromosome condensation GO:0030261 48 25 0,000 0,06803341 0,08462608 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,06803341 0,08458301 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06803341 0,08453999 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06803341 0,08449701 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06803341 0,08445407 ! immunoglobulin production GO:0002377 62 25 0,000 0,06803341 0,08441118 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06803341 0,08436833 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06803341 0,08432553 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06803341 0,08428277 ! liver development GO:0001889 55 25 0,000 0,06803341 0,08424005 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,07065726 0,08744462 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,07065726 0,08740035 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,07065726 0,08735612 ! molting cycle process GO:0022404 52 26 0,000 0,07065726 0,08731193 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,07065726 0,08726779 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,07065726 0,08722369 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,07065726 0,08717964 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,07065726 0,08713563 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,07065726 0,08709167 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,07065726 0,08704775 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,07065726 0,08700388 ! digestive system process GO:0022600 49 26 0,000 0,07065726 0,08696005 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,07065726 0,08691626 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,07065726 0,08687252 ! osteoblast differentiation GO:0001649 63 26 0,000 0,07065726 0,08682882 ! neural crest cell development GO:0014032 59 26 0,000 0,07065726 0,08678516 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,07065726 0,08674155 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,07065726 0,08669799 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,07065726 0,08665446 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,07065726 0,08661098 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,07065726 0,08656755 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,07065726 0,08652416 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,07065726 0,08648081 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,07065726 0,0864375 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,07065726 0,08639424 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,07065726 0,08635102 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,07065726 0,08630784 ! neural tube closure GO:0001843 58 26 0,000 0,07065726 0,08626471 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,07065726 0,08622162 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,07065726 0,08617858 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,07065726 0,08613557 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0732738 0,08928075 ! embryonic pattern specification GO:0009880 49 27 0,000 0,0732738 0,08923624 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0732738 0,08919178 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0732738 0,08914736 ! iron ion transport GO:0006826 65 27 0,000 0,0732738 0,08910299 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0732738 0,08905866 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0732738 0,08901437 ! tube lumen formation GO:0035148 59 27 0,000 0,0732738 0,08897013 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,0732738 0,08892593 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,0732738 0,08888178 ! response to toxin GO:0009636 49 27 0,000 0,0732738 0,08883767 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0732738 0,0887936 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0732738 0,08874958 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,07588305 0,09186436 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07588305 0,09181886 ! vesicle docking GO:0048278 55 28 0,000 0,07588305 0,09177341 ! circadian rhythm GO:0007623 56 28 0,000 0,07588305 0,091728 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07588305 0,09168263 ! sperm motility GO:0030317 37 28 0,000 0,07588305 0,09163731 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07588305 0,09159204 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07588305 0,09154681 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07588305 0,09150162 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07588305 0,09145648 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07588305 0,09141138 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07588305 0,09136633 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07588305 0,09132132 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07588305 0,09127636 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07588305 0,09123144 ! lipid oxidation GO:0034440 48 28 0,000 0,07588305 0,09118657 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07588305 0,09114173 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,07848502 0,09422059 ! translational initiation GO:0006413 66 29 0,000 0,07848502 0,09417432 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,07848502 0,09412808 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,07848502 0,0940819 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,07848502 0,09403576 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07848502 0,09398966 ! primary neural tube formation GO:0014020 61 29 0,000 0,07848502 0,09394361 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,07848502 0,0938976 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,07848502 0,09385164 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,07848502 0,09380573 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,07848502 0,09375986 ! somitogenesis GO:0001756 52 29 0,000 0,07848502 0,09371403 ! synaptogenesis GO:0007416 46 29 0,000 0,07848502 0,09366825 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07848502 0,09362251 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07848502 0,09357682 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07848502 0,09353117 ! phenol metabolic process GO:0018958 56 30 0,000 0,08107974 0,09657621 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,08107974 0,09652915 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,08107974 0,09648213 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,08107974 0,09643516 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,08107974 0,09638823 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,08107974 0,09634135 ! acute-phase response GO:0006953 50 30 0,000 0,08107974 0,09629451 ! myofibril assembly GO:0030239 50 30 0,000 0,08107974 0,09624772 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,08107974 0,09620098 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,08107974 0,09615428 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,08107974 0,09610762 ! cell fate determination GO:0001709 64 30 0,000 0,08107974 0,09606101 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,08107974 0,09601445 ! phospholipid transport GO:0015914 65 30 0,000 0,08107974 0,09596793 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,08107974 0,09592146 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,08107974 0,09587503 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,08107974 0,09582865 ! regulation of coagulation GO:0050818 52 30 0,000 0,08107974 0,09578231 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08366723 0,09879122 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08366723 0,0987435 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08366723 0,09869582 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08366723 0,09864819 ! cell junction assembly GO:0034329 85 31 0,000 0,08366723 0,0986006 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08366723 0,09855306 ! ovulation cycle process GO:0022602 55 31 0,000 0,08366723 0,09850556 ! peptide transport GO:0015833 60 31 0,000 0,08366723 0,09845811 ! male gonad development GO:0008584 56 31 0,000 0,08366723 0,09841071 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,08366723 0,09836335 ! detection of light stimulus GO:0009583 44 31 0,000 0,08366723 0,09831604 ! natural killer cell activation GO:0030101 50 31 0,000 0,08366723 0,09826877 ! cofactor catabolic process GO:0051187 54 31 0,000 0,08366723 0,09822155 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,08366723 0,09817437 ! eye morphogenesis GO:0048592 65 31 0,000 0,08366723 0,09812724 ! response to heat GO:0009408 54 31 0,000 0,08366723 0,09808015 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08366723 0,09803311 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,0862475 0,10100798 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,0862475 0,10095958 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,0862475 0,10091123 ! spindle organization GO:0007051 50 32 0,000 0,0862475 0,10086293 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,0862475 0,10081467 ! metanephros development GO:0001656 81 32 0,000 0,0862475 0,10076645 ! muscle cell development GO:0055001 52 32 0,000 0,0862475 0,10071829 ! mesoderm formation GO:0001707 73 32 0,000 0,0862475 0,10067016 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,0862475 0,10062209 ! ovulation cycle GO:0042698 57 32 0,000 0,0862475 0,10057406 ! BMP signaling pathway GO:0030509 71 32 0,000 0,0862475 0,10052607 ! hindbrain development GO:0030902 65 32 0,000 0,0862475 0,10047814 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,0862475 0,10043024 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,0862475 0,1003824 ! gene silencing GO:0016458 71 32 0,000 0,0862475 0,1003346 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,08882058 0,10327877 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,08882058 0,10322963 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,08882058 0,10318055 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,08882058 0,10313151 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,08882058 0,10308251 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,08882058 0,10303357 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,08882058 0,10298466 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,08882058 0,10293581 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,08882058 0,102887 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,08882058 0,10283824 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,09138649 0,10575898 ! glial cell differentiation GO:0010001 67 34 0,000 0,09138649 0,1057089 ! post-embryonic development GO:0009791 76 34 0,000 0,09138649 0,10565887 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,09138649 0,10560889 ! cholesterol transport GO:0030301 62 34 0,000 0,09138649 0,10555896 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,09138649 0,10550907 ! spliceosome assembly GO:0000245 75 34 0,000 0,09138649 0,10545924 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,09138649 0,10540944 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,09138649 0,1053597 ! formation of primary germ layer GO:0001704 76 34 0,000 0,09138649 0,10531 ! cell fate specification GO:0001708 56 34 0,000 0,09138649 0,10526035 ! adult locomotory behavior GO:0008344 62 34 0,000 0,09138649 0,10521075 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,09394525 0,10810562 ! negative regulation of secretion GO:0051048 68 35 0,000 0,09394525 0,10805473 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,09394525 0,10800388 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,09394525 0,10795307 ! membrane docking GO:0022406 69 35 0,000 0,09394525 0,10790232 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,09394525 0,10785162 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,09394525 0,10780096 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,09394525 0,10775035 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,09394525 0,10769978 ! ceramide metabolic process GO:0006672 72 35 0,000 0,09394525 0,10764927 ! sterol transport GO:0015918 63 35 0,000 0,09394525 0,1075988 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,09394525 0,10754838 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,09394525 0,107498 ! vesicle localization GO:0051648 70 35 0,000 0,09394525 0,10744768 ! regulation of muscle development GO:0048634 82 36 0,000 0,09649687 0,11031439 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,09649687 0,11026279 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,09649687 0,11021124 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,09649687 0,11015974 ! positive regulation of cell development GO:0010720 85 36 0,000 0,09649687 0,11010829 ! protein targeting to membrane GO:0006612 75 36 0,000 0,09649687 0,11005688 ! regulation of proteolysis GO:0030162 77 36 0,000 0,09649687 0,11000553 ! aerobic respiration GO:0009060 56 36 0,000 0,09649687 0,10995422 ! cytokine production GO:0001816 68 36 0,000 0,09649687 0,10990296 ! embryonic organ development GO:0048568 67 36 0,000 0,09649687 0,10985174 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,09649687 0,10980058 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,09649687 0,10974946 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,09904137 0,11259101 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,09904137 0,11253864 ! sister chromatid segregation GO:0000819 65 37 0,000 0,09904137 0,11248632 ! odontogenesis GO:0042476 74 37 0,000 0,09904137 0,11243405 ! actomyosin structure organization GO:0031032 68 37 0,000 0,09904137 0,11238183 ! cell junction organization GO:0034330 96 37 0,000 0,09904137 0,11232965 ! tissue remodeling GO:0048771 78 37 0,000 0,09904137 0,11227753 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,09904137 0,11222545 ! female gonad development GO:0008585 71 37 0,000 0,09904137 0,11217342 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,09904137 0,11212144 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,09904137 0,11206951 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,10157878 0,11488749 ! meiosis I GO:0007127 74 38 0,000 0,10157878 0,11483432 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,10157878 0,11478121 ! organic anion transport GO:0015711 82 38 0,000 0,10157878 0,11472814 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,10157878 0,11467512 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,10157878 0,11462216 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,10157878 0,11456924 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,10157878 0,11451637 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,10157878 0,11446355 ! spermatid development GO:0007286 69 38 0,000 0,10157878 0,11441077 ! pigment metabolic process GO:0042440 87 38 0,000 0,10157878 0,11435805 ! neural tube formation GO:0001841 79 38 0,000 0,10157878 0,11430537 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,10410912 0,11709879 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,10410912 0,11704491 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,10410912 0,11699107 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,10410912 0,11693728 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,10410912 0,11688354 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,10410912 0,11682985 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,10410912 0,11677621 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,10410912 0,11672262 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,1066324 0,11949677 ! learning GO:0007612 82 40 0,000 0,1066324 0,11944198 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,1066324 0,11938724 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,1066324 0,11933255 ! mismatch repair GO:0006298 58 40 0,000 0,1066324 0,11927791 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,1066324 0,11922332 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,1066324 0,11916878 ! RNA export from nucleus GO:0006405 61 41 0,000 0,10914865 0,12192508 ! mRNA catabolic process GO:0006402 79 41 0,000 0,10914865 0,12186935 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,10914865 0,12181368 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,10914865 0,12175806 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,10914865 0,12170248 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,10914865 0,12164696 ! gliogenesis GO:0042063 91 41 0,000 0,10914865 0,12159149 ! feeding behavior GO:0007631 69 41 0,000 0,10914865 0,12153607 ! mesenchymal cell development GO:0014031 94 41 0,000 0,10914865 0,1214807 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,10914865 0,12142538 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,10914865 0,12137011 ! spermatid differentiation GO:0048515 73 41 0,000 0,10914865 0,1213149 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,10914865 0,12125973 ! RNA modification GO:0009451 64 41 0,000 0,10914865 0,12120461 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,11165787 0,12393466 ! organic ether metabolic process GO:0018904 59 42 0,000 0,11165787 0,12387838 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,11165787 0,12382215 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,11165787 0,12376596 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,11165787 0,12370984 ! regulation of protein secretion GO:0050708 77 42 0,000 0,11165787 0,12365376 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,11165787 0,12359773 ! cytokinesis GO:0000910 84 42 0,000 0,11165787 0,12354175 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,11165787 0,12348582 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,11416011 0,12619599 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,11416011 0,12613891 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,11416011 0,12608189 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,11416011 0,12602492 ! regulation of tube size GO:0035150 76 43 0,000 0,11416011 0,12596799 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,11416011 0,12591112 ! glucose transport GO:0015758 66 43 0,000 0,11416011 0,1258543 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,11416011 0,12579754 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,11416011 0,12574082 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,11416011 0,12568415 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,11416011 0,12562754 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,11416011 0,12557098 ! segmentation GO:0035282 78 43 0,000 0,11416011 0,12551446 ! ion transmembrane transport GO:0034220 79 43 0,000 0,11416011 0,125458 ! neuron migration GO:0001764 85 43 0,000 0,11416011 0,12540159 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,11416011 0,12534523 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,11665536 0,12802742 ! hexose transport GO:0008645 68 44 0,000 0,11665536 0,12796993 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,11665536 0,1279125 ! striated muscle contraction GO:0006941 85 44 0,000 0,11665536 0,12785511 ! phagocytosis GO:0006909 105 44 0,000 0,11665536 0,12779778 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,11665536 0,12774049 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,11914365 0,13040679 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,11914365 0,13034839 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,11914365 0,13029004 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,11914365 0,13023174 ! female gamete generation GO:0007292 71 45 0,000 0,11914365 0,1301735 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,11914365 0,13011531 ! polyol metabolic process GO:0019751 77 45 0,000 0,11914365 0,13005717 ! developmental growth GO:0048589 88 45 0,000 0,11914365 0,12999908 ! maintenance of location in cell GO:0051651 101 45 0,000 0,11914365 0,12994105 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,12162501 0,13258808 ! glycolysis GO:0006096 71 46 0,000 0,12162501 0,13252895 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,12162501 0,13246986 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,12162501 0,13241083 ! cell growth GO:0016049 90 46 0,000 0,12162501 0,13235185 ! neural tube development GO:0021915 91 47 0,000 0,12409944 0,13498439 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,12409944 0,13492432 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,12656698 0,13754588 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,12656698 0,13748472 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,12656698 0,13742361 ! endosome transport GO:0016197 127 48 0,000 0,12656698 0,13736256 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,12656698 0,13730157 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,12656698 0,13724062 ! male sex differentiation GO:0046661 93 48 0,000 0,12656698 0,13717974 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,12656698 0,1371189 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,12656698 0,13705812 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,12656698 0,1369974 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,12902763 0,13959898 ! JNK cascade GO:0007254 106 49 0,000 0,12902763 0,13953718 ! protein homooligomerization GO:0051260 84 49 0,000 0,12902763 0,13947544 ! regulation of ion transport GO:0043269 86 50 0,000 0,13148142 0,14206506 ! endocrine system development GO:0035270 109 50 0,000 0,13148142 0,14200226 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,13148142 0,14193951 ! regulation of ossification GO:0030278 123 50 0,000 0,13148142 0,14187681 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,13148142 0,14181417 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,13148142 0,14175159 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,13392836 0,14432598 ! peptide metabolic process GO:0006518 80 51 0,000 0,13392836 0,14426234 ! response to temperature stimulus GO:0009266 84 51 0,000 0,13392836 0,14419876 ! positive regulation of binding GO:0051099 88 52 0,000 0,13636848 0,14676132 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,13636848 0,1466967 ! Notch signaling pathway GO:0007219 111 52 0,000 0,13636848 0,14663213 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,13636848 0,14656762 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,13636848 0,14650317 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,13636848 0,14643877 ! excretion GO:0007588 87 52 0,000 0,13636848 0,14637443 ! histone modification GO:0016570 104 52 0,000 0,13636848 0,14631015 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,13636848 0,14624592 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,13636848 0,14618175 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,13636848 0,14611763 ! amino acid activation GO:0043038 98 52 0,000 0,13636848 0,14605357 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,1388018 0,14859456 ! inner ear development GO:0048839 89 53 0,000 0,1388018 0,14852947 ! chromatin remodeling GO:0006338 122 53 0,000 0,1388018 0,14846444 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,1388018 0,14839947 ! vesicle organization GO:0016050 127 53 0,000 0,1388018 0,14833455 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,14122832 0,15086174 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,14122832 0,1507958 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,14122832 0,15072992 ! membrane fusion GO:0006944 122 54 0,000 0,14122832 0,1506641 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,14122832 0,15059834 ! covalent chromatin modification GO:0016569 115 54 0,000 0,14122832 0,15053263 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,14122832 0,15046698 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,14122832 0,15040139 ! RNA catabolic process GO:0006401 103 55 0,000 0,14364808 0,15291166 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,14364808 0,15284506 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,14364808 0,15277852 ! cell recognition GO:0008037 98 55 0,000 0,14364808 0,15271203 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,14364808 0,15264561 ! cell maturation GO:0048469 107 55 0,000 0,14364808 0,15257924 ! glucose catabolic process GO:0006007 88 56 0,000 0,14606109 0,15507485 ! RNA elongation GO:0006354 90 56 0,000 0,14606109 0,15500749 ! chloride transport GO:0006821 102 57 0,000 0,14846736 0,15749273 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,14846736 0,15742438 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,14846736 0,15735608 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,15086692 0,15982996 ! gastrulation GO:0007369 122 58 0,000 0,15086692 0,15976068 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,15086692 0,15969146 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,15086692 0,1596223 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,15086692 0,1595532 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,15086692 0,15948416 ! maintenance of location GO:0051235 124 58 0,000 0,15086692 0,15941518 ! nuclear export GO:0051168 110 59 0,000 0,15325979 0,16187361 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,15564598 0,16432288 ! regulation of endocytosis GO:0030100 104 60 0,000 0,15564598 0,16425189 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,15564598 0,16418097 ! adult behavior GO:0030534 104 60 0,000 0,15564598 0,16411011 ! kidney development GO:0001822 133 60 0,000 0,15564598 0,16403932 ! positive regulation of secretion GO:0051047 110 61 0,000 0,15802552 0,16647535 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,15802552 0,16640359 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,15802552 0,1663319 ! camera-type eye development GO:0043010 126 61 0,000 0,15802552 0,16626027 ! proton transport GO:0015992 117 61 0,000 0,15802552 0,16618869 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,16039841 0,16861158 ! tRNA processing GO:0008033 102 62 0,000 0,16039841 0,16853906 ! regulation of mitosis GO:0007088 112 63 0,000 0,16276469 0,1709519 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,16276469 0,17087844 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,16276469 0,17080504 ! hydrogen transport GO:0006818 121 64 0,000 0,16512436 0,17320687 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,16512436 0,17313254 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,16747745 0,17552441 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,16747745 0,17544914 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,16747745 0,17537394 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,16982397 0,17775491 ! gonad development GO:0008406 115 66 0,000 0,16982397 0,17767878 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,16982397 0,17760272 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,17216394 0,17997283 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,17216394 0,17989586 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,17216394 0,17981895 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,17216394 0,1797421 ! secondary metabolic process GO:0019748 125 67 0,000 0,17216394 0,17966532 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,17449739 0,18202268 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,17449739 0,18194499 ! hexose catabolic process GO:0019320 113 68 0,000 0,17449739 0,18186737 ! extracellular matrix organization GO:0030198 146 68 0,000 0,17449739 0,18178982 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,17449739 0,18171233 ! regulation of lipase activity GO:0060191 137 68 0,000 0,17449739 0,1816349 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,17449739 0,18155755 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,17682432 0,1839003 ! lung development GO:0030324 165 69 0,000 0,17682432 0,18382205 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,17682432 0,18374386 ! urogenital system development GO:0001655 149 69 0,000 0,17682432 0,18366574 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,17682432 0,18358768 ! developmental maturation GO:0021700 128 69 0,000 0,17682432 0,18350969 ! single fertilization GO:0007338 83 69 0,000 0,17682432 0,18343177 ! cell redox homeostasis GO:0045454 114 70 0,000 0,17914476 0,18576004 ! germ cell development GO:0007281 133 70 0,000 0,17914476 0,18568122 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,18145872 0,18799986 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,18145872 0,18792016 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,18145872 0,18784053 ! appendage morphogenesis GO:0035107 150 72 0,000 0,18376623 0,19014862 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,18376623 0,19006812 ! respiratory tube development GO:0030323 171 72 0,000 0,18376623 0,18998768 ! actin filament organization GO:0007015 167 72 0,000 0,18376623 0,18990732 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,18376623 0,18982702 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,18376623 0,18974679 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,18376623 0,18966662 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,18376623 0,18958653 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,18376623 0,1895065 ! appendage development GO:0048736 151 73 0,000 0,18606729 0,19179848 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,18606729 0,19171759 ! regulation of immune effector process GO:0002697 156 73 0,000 0,18606729 0,19163676 ! amino acid transport GO:0006865 148 74 0,000 0,18836194 0,19391833 ! respiratory system development GO:0060541 175 74 0,000 0,18836194 0,19383665 ! transition metal ion transport GO:0000041 143 75 0,000 0,19065017 0,19610879 ! reproductive structure development GO:0048608 131 75 0,000 0,19065017 0,19602625 ! eye development GO:0001654 155 75 0,000 0,19065017 0,19594378 ! rhythmic process GO:0048511 142 75 0,000 0,19065017 0,19586138 ! learning or memory GO:0007611 161 76 0,000 0,19293202 0,19812229 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,19293202 0,19803905 ! regulation of blood pressure GO:0008217 134 76 0,000 0,19293202 0,19795587 ! neurotransmitter transport GO:0006836 142 77 0,000 0,19520751 0,20020652 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,19520751 0,20012251 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,19520751 0,20003856 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,19520751 0,19995469 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,19520751 0,19987089 ! fertilization GO:0009566 99 78 0,000 0,19747664 0,20210952 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,19747664 0,20202488 ! blood coagulation GO:0007596 151 79 0,000 0,19973943 0,20425426 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,19973943 0,2041688 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,19973943 0,20408341 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,20199591 0,20630268 ! meiosis GO:0007126 143 81 0,000 0,20424609 0,20851367 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,20424609 0,20842657 ! response to hypoxia GO:0001666 178 81 0,000 0,20424609 0,20833954 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,20424609 0,20825259 ! meiotic cell cycle GO:0051321 144 82 0,000 0,20648999 0,21045267 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,20872763 0,21264453 ! exocytosis GO:0006887 153 83 0,000 0,20872763 0,2125559 ! response to oxygen levels GO:0070482 183 83 0,000 0,20872763 0,21246733 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,20872763 0,21237884 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,20872763 0,21229042 ! inorganic anion transport GO:0015698 156 83 0,000 0,20872763 0,21220208 ! response to nutrient GO:0007584 135 84 0,000 0,21095902 0,2143814 ! digestion GO:0007586 130 84 0,000 0,21095902 0,21429226 ! hemostasis GO:0007599 165 85 0,000 0,21318417 0,21646257 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,21318417 0,21637264 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,21318417 0,21628278 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,21318417 0,216193 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,21540312 0,21835262 ! regulation of lyase activity GO:0051339 169 86 0,000 0,21540312 0,21826206 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,21540312 0,21817157 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,21761587 0,22032141 ! alcohol catabolic process GO:0046164 142 87 0,000 0,21761587 0,22023014 ! nucleosome assembly GO:0006334 126 87 0,000 0,21761587 0,22013895 ! cellular respiration GO:0045333 143 88 0,000 0,21982244 0,22227907 ! amine biosynthetic process GO:0009309 146 88 0,000 0,21982244 0,2221871 ! sensory perception of smell GO:0007608 117 88 0,000 0,21982244 0,22209521 ! chromatin assembly GO:0031497 128 88 0,000 0,21982244 0,2220034 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,22202285 0,22413299 ! tube morphogenesis GO:0035239 194 89 0,000 0,22202285 0,22404041 ! cellular defense response GO:0006968 123 89 0,000 0,22202285 0,2239479 ! regulation of neurological system process GO:0031644 175 89 0,000 0,22202285 0,22385548 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,22421712 0,22597459 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,22640526 0,22808579 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,22640526 0,22799177 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,22858729 0,23009425 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,23076322 0,23218886 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,23076322 0,23209327 ! vitamin metabolic process GO:0006766 153 93 0,000 0,23076322 0,23199776 ! sterol metabolic process GO:0016125 166 94 0,000 0,23293308 0,23408289 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,23293308 0,23398664 ! nucleosome organization GO:0034728 143 95 0,000 0,23509688 0,23606316 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,23509688 0,23596618 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,23509688 0,23586927 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,23509688 0,23577245 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,23509688 0,2356757 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,23509688 0,23557903 ! sex differentiation GO:0007548 171 96 0,000 0,23725464 0,23764374 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,23940637 0,23970072 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,24155209 0,24175 ! mRNA transport GO:0051028 185 100 0,000 0,24582557 0,24592623 ! hormone metabolic process GO:0042445 171 100 0,000 0,24582557 0,24582557