pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6119-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 12 6 3,000 1,509E-09 3,631E-06 ! establishment of nucleus localization GO:0040023 16 8 3,000 7,007E-09 8,429E-06 ! nucleus localization GO:0051647 19 11 3,000 3,279E-08 2,63E-05 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 6,432E-07 3,869E-04 GO:0031272|regulation of pseudopodium assembly, ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 6,583E-07 3,168E-04 ! interphase GO:0051325 213 98 5,000 7,912E-07 3,173E-04 ! cell cycle arrest GO:0007050 213 100 5,000 8,913E-07 3,064E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 1,123E-06 3,377E-04 ! macrophage differentiation GO:0030225 11 7 2,000 1,123E-06 3,002E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 1,482E-06 3,567E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,676E-06 3,666E-04 ! ER overload response GO:0006983 12 8 2,000 1,793E-06 3,594E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,793E-06 3,318E-04 ! negative regulation of protein complex assembly GO:0031333 59 29 3,000 2,257E-06 3,879E-04 ! cellular response to extracellular stimulus GO:0031668 48 29 3,000 2,257E-06 3,621E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 2,575E-06 3,872E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 2,772E-06 3,924E-04 ! regulation of caspase activity GO:0043281 122 72 4,000 3,684E-06 4,924E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 3,684E-06 4,664E-04 ! regulation of endopeptidase activity GO:0052548 125 74 4,000 4,219E-06 5,076E-04 ! sequestering of metal ion GO:0051238 14 11 2,000 5,245E-06 6,009E-04 ! regulation of embryonic development GO:0045995 27 11 2,000 5,245E-06 5,736E-04 ! regulation of peptidase activity GO:0052547 134 79 4,000 5,829E-06 6,097E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 6,977E-06 6,994E-04 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 6,977E-06 6,714E-04 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,03E-05 9,533E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,133E-05 1,01E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 1,149E-05 9,872E-04 ! maintenance of location in cell GO:0051651 97 44 3,000 1,243E-05 1,031E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 1,297E-05 1,04E-03 ! detection of bacterium GO:0016045 18 15 2,000 1,433E-05 1,112E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 1,487E-05 1,118E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,487E-05 1,084E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,759E-05 1,245E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 1,759E-05 1,209E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,131E-05 1,424E-03 ! microspike assembly GO:0030035 36 17 2,000 2,131E-05 1,386E-03 ! response to UV GO:0009411 104 53 3,000 2,623E-05 1,661E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 3,504E-05 2,161E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 3,504E-05 2,107E-03 ! maintenance of location GO:0051235 118 57 3,000 3,504E-05 2,056E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 3,548E-05 2,033E-03 ! cellular response to starvation GO:0009267 33 20 2,000 3,548E-05 1,985E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,548E-05 1,94E-03 ! establishment of organelle localization GO:0051656 109 59 3,000 4,017E-05 2,148E-03 ! detection of biotic stimulus GO:0009595 29 21 2,000 4,13E-05 2,16E-03 ! regulation of protein complex assembly GO:0043254 117 61 3,000 4,583E-05 2,346E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,771E-05 2,391E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 4,771E-05 2,342E-03 ! viral reproductive process GO:0022415 126 62 3,000 4,887E-05 2,352E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 5,473E-05 2,582E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 5,473E-05 2,533E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 6,241E-05 2,833E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 6,241E-05 2,781E-03 ! protein tetramerization GO:0051262 52 24 2,000 6,241E-05 2,73E-03 ! viral reproduction GO:0016032 134 68 3,000 7,03E-05 3,021E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 7,075E-05 2,986E-03 ! response to starvation GO:0042594 42 25 2,000 7,075E-05 2,935E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 7,075E-05 2,885E-03 ! negative regulation of cell development GO:0010721 73 25 2,000 7,075E-05 2,837E-03 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 2,000 7,075E-05 2,791E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 7,075E-05 2,746E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 7,979E-05 3,047E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 7,979E-05 3E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 8,956E-05 3,315E-03 ! iron ion transport GO:0006826 59 27 2,000 8,956E-05 3,265E-03 ! organelle localization GO:0051640 136 74 3,000 9,787E-05 3,515E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,001E-04 3,541E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,02E-04 3,557E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,02E-04 3,507E-03 ! transepithelial chloride transport GO:0030321 9 5 1,000 1,02E-04 3,457E-03 GO:0070633|transepithelial transport, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,02E-04 3,409E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 1,02E-04 3,363E-03 ! steroid biosynthetic process GO:0006694 131 76 3,000 1,086E-04 3,531E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 1,086E-04 3,484E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 1,114E-04 3,525E-03 ! protein oligomerization GO:0051259 139 78 3,000 1,201E-04 3,754E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 1,363E-04 4,206E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,501E-04 4,572E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,501E-04 4,514E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 1,527E-04 4,536E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 1,527E-04 4,481E-03 ! male sex determination GO:0030238 15 6 1,000 1,527E-04 4,427E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 1,527E-04 4,374E-03 GO:0045686|negative regulation of glial cell differentiation, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,527E-04 4,323E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,527E-04 4,272E-03 ! regulation of viral transcription GO:0046782 10 6 1,000 1,527E-04 4,223E-03 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,647E-04 4,504E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,802E-04 4,873E-03 ! regulation of protein transport GO:0051223 154 87 3,000 1,834E-04 4,902E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 3,000 1,916E-04 5,067E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 1,967E-04 5,144E-03 ! regulation of cell adhesion GO:0030155 212 89 3,000 2,002E-04 5,179E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,133E-04 5,461E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,133E-04 5,403E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,133E-04 5,347E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,133E-04 5,292E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,133E-04 5,238E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,133E-04 5,185E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,133E-04 5,133E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,133E-04 5,082E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 2,324E-04 5,482E-03 ! negative regulation of DNA binding GO:0043392 68 37 2,000 2,324E-04 5,429E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,324E-04 5,377E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 2,677E-04 6,134E-03 ! regulation of protein localization GO:0032880 176 97 3,000 2,785E-04 6,322E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,839E-04 6,383E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,839E-04 6,324E-03 ! glycine catabolic process GO:0006546 13 8 1,000 2,839E-04 6,266E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 2,839E-04 6,209E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,839E-04 6,153E-03 ! negative regulation of binding GO:0051100 72 40 2,000 2,935E-04 6,304E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,642E-04 7,755E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,642E-04 7,687E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,642E-04 7,62E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,642E-04 7,554E-03 ! receptor clustering GO:0043113 18 9 1,000 3,642E-04 7,489E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,642E-04 7,426E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,642E-04 7,364E-03 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 3,642E-04 7,302E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 4,166E-04 8,284E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,446E-04 8,769E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 4,446E-04 8,697E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 4,446E-04 8,627E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,543E-04 8,744E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,543E-04 8,675E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 4,543E-04 8,607E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,543E-04 8,539E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 4,543E-04 8,473E-03 GO:0045685|regulation of glial cell differentiation, ! positive regulation of viral reproduction GO:0048524 18 10 1,000 4,543E-04 8,408E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,543E-04 8,344E-03 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 4,543E-04 8,281E-03 ! activation of caspase activity GO:0006919 84 48 2,000 5,043E-04 9,122E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 5,043E-04 9,054E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 5,359E-04 9,551E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,541E-04 9,802E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,541E-04 9,731E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,541E-04 9,66E-03 ! neuroblast proliferation GO:0007405 24 11 1,000 5,541E-04 9,591E-03 ! nucleosome positioning GO:0016584 15 11 1,000 5,541E-04 9,522E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 5,688E-04 9,705E-03 ! viral infectious cycle GO:0019058 99 51 2,000 6,029E-04 0,01021546 ! chromatin remodeling GO:0006338 109 51 2,000 6,029E-04 0,01014402 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 6,029E-04 0,01007358 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,635E-04 0,01100962 ! virus-host interaction GO:0019048 29 12 1,000 6,635E-04 0,01093421 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,635E-04 0,01085983 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 6,635E-04 0,01078645 ! hippocampus development GO:0021766 26 12 1,000 6,635E-04 0,01071406 ! entry into host cell GO:0030260 32 12 1,000 6,635E-04 0,01064263 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 6,635E-04 0,01057215 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,635E-04 0,0105026 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 6,635E-04 0,01043395 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of caspase activity GO:0043280 95 55 2,000 7,525E-04 0,01175646 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 7,525E-04 0,01168061 ! response to X-ray GO:0010165 25 13 1,000 7,825E-04 0,01206853 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 7,825E-04 0,01199166 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,825E-04 0,01191576 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,825E-04 0,01184082 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,825E-04 0,01176681 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 7,825E-04 0,01169373 ! regulation of DNA replication GO:0006275 101 56 2,000 7,932E-04 0,01178104 ! positive regulation of cell migration GO:0030335 126 57 2,000 8,354E-04 0,01233052 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 9,11E-04 0,01336503 ! regulation of mRNA processing GO:0050684 24 14 1,000 9,11E-04 0,01328403 ! negative regulation of caspase activity GO:0043154 22 14 1,000 9,11E-04 0,01320401 ! bone mineralization GO:0030282 17 14 1,000 9,11E-04 0,01312494 ! response to gamma radiation GO:0010332 28 14 1,000 9,11E-04 0,01304681 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 9,11E-04 0,01296961 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 9,11E-04 0,01289332 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,018E-03 0,01432315 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,049E-03 0,01467309 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,049E-03 0,01458827 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 1,118E-03 0,01545947 ! detection of external stimulus GO:0009581 91 63 2,000 1,118E-03 0,01537113 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,17E-03 0,01599821 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,196E-03 0,01626137 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,196E-03 0,01617002 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 1,196E-03 0,01607968 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,196E-03 0,01599035 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 1,196E-03 0,01590201 ! biomineral formation GO:0031214 20 16 1,000 1,196E-03 0,01581463 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,196E-03 0,01572821 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,196E-03 0,01564273 ! myeloid cell differentiation GO:0030099 111 65 2,000 1,224E-03 0,01591932 ! cell projection assembly GO:0030031 120 66 2,000 1,279E-03 0,0165492 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,336E-03 0,01719229 ! activation of MAPK activity GO:0000187 115 67 2,000 1,336E-03 0,01710085 ! signal complex assembly GO:0007172 41 17 1,000 1,353E-03 0,01722325 ! limbic system development GO:0021761 36 17 1,000 1,353E-03 0,0171326 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 1,353E-03 0,0170429 ! glycine metabolic process GO:0006544 28 17 1,000 1,353E-03 0,01695414 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,353E-03 0,01686629 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 1,000 1,353E-03 0,01677935 ! negative regulation of cell size GO:0045792 134 69 2,000 1,455E-03 0,01794829 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,519E-03 0,018645 ! centrosome cycle GO:0007098 25 18 1,000 1,519E-03 0,01855035 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,519E-03 0,01845667 ! lipid phosphorylation GO:0046834 35 19 1,000 1,694E-03 0,02048138 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,694E-03 0,02037897 ! neuromuscular junction development GO:0007528 34 19 1,000 1,694E-03 0,02027759 ! G1 phase GO:0051318 40 19 1,000 1,694E-03 0,0201772 ! axon guidance GO:0007411 139 73 2,000 1,711E-03 0,02027718 ! regulation of transcription factor activity GO:0051090 126 74 2,000 1,779E-03 0,02098159 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 2,000 1,779E-03 0,02087925 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,878E-03 0,02193775 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,878E-03 0,02183177 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,878E-03 0,02172681 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,878E-03 0,02162285 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,878E-03 0,02151988 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,878E-03 0,02141789 ! cell aging GO:0007569 44 21 1,000 2,072E-03 0,02351141 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 2,072E-03 0,02340103 ! activation of protein kinase activity GO:0032147 147 79 2,000 2,145E-03 0,02411794 ! protein import into nucleus GO:0006606 158 80 2,000 2,224E-03 0,02488326 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,274E-03 0,02533048 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,274E-03 0,02521375 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,274E-03 0,02509809 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,274E-03 0,02498348 ! activation of JUN kinase activity GO:0007257 42 22 1,000 2,274E-03 0,02486992 ! protein stabilization GO:0050821 39 22 1,000 2,274E-03 0,02475739 ! nuclear import GO:0051170 161 81 2,000 2,304E-03 0,02496754 ! regulation of neuron differentiation GO:0045664 167 81 2,000 2,304E-03 0,02485558 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,386E-03 0,02562478 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,485E-03 0,02657744 ! viral genome replication GO:0019079 41 23 1,000 2,485E-03 0,02645985 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,485E-03 0,02634328 GO:0010810|regulation of cell-substrate adhesion, ! barbed-end actin filament capping GO:0051016 50 23 1,000 2,485E-03 0,02622774 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 1,000 2,485E-03 0,02611321 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,485E-03 0,02599967 ! regulation of viral reproduction GO:0050792 38 23 1,000 2,485E-03 0,02588712 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,485E-03 0,02577554 ! negative regulation of transport GO:0051051 153 84 2,000 2,555E-03 0,02638278 ! negative regulation of growth GO:0045926 155 84 2,000 2,555E-03 0,02627003 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,706E-03 0,02770172 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,706E-03 0,02758434 ! pallium development GO:0021543 49 24 1,000 2,706E-03 0,02746795 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,706E-03 0,02735254 ! protein localization in nucleus GO:0034504 176 87 2,000 2,822E-03 0,02841344 ! myelination GO:0042552 45 25 1,000 2,935E-03 0,02942159 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 2,935E-03 0,0292995 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,935E-03 0,02917843 ! receptor metabolic process GO:0043112 46 25 1,000 2,935E-03 0,02905836 ! somitogenesis GO:0001756 43 25 1,000 2,935E-03 0,02893926 ! ossification GO:0001503 188 90 2,000 3,107E-03 0,03050811 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 3,173E-03 0,03103095 ! negative regulation of actin filament polymerization GO:0030837 53 26 1,000 3,173E-03 0,03090532 ! initiation of viral infection GO:0019059 57 26 1,000 3,173E-03 0,0307807 ! microtubule organizing center organization GO:0031023 39 26 1,000 3,173E-03 0,03065708 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,173E-03 0,03053445 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,173E-03 0,0304128 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 3,173E-03 0,03029212 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 3,173E-03 0,03017239 ! bone development GO:0060348 189 91 2,000 3,205E-03 0,0303599 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,419E-03 0,032263 ! protein amino acid acylation GO:0043543 55 27 1,000 3,419E-03 0,03213697 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,419E-03 0,03201192 ! base-excision repair GO:0006284 41 27 1,000 3,419E-03 0,03188785 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 3,419E-03 0,03176473 ! negative regulation of protein polymerization GO:0032272 55 27 1,000 3,419E-03 0,03164256 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,419E-03 0,03152132 ! transcription initiation GO:0006352 153 94 2,000 3,512E-03 0,03225078 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 3,675E-03 0,03361747 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 3,675E-03 0,03349013 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,675E-03 0,03336375 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 3,675E-03 0,03323833 ! detection of stimulus GO:0051606 151 96 2,000 3,726E-03 0,03357713 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 3,836E-03 0,03443965 ! regulation of pH GO:0006885 43 29 1,000 3,939E-03 0,0352285 ! tissue homeostasis GO:0001894 48 29 1,000 3,939E-03 0,03509802 GO:0048871|multicellular organismal homeostasis, ! skeletal muscle tissue development GO:0007519 186 99 2,000 4,062E-03 0,03606457 GO:0060538|skeletal muscle organ development, ! ensheathment of neurons GO:0007272 57 30 1,000 4,211E-03 0,03725052 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 4,211E-03 0,03711407 ! regulation of B cell activation GO:0050864 50 30 1,000 4,211E-03 0,03697862 ! serine family amino acid metabolic process GO:0009069 49 31 1,000 4,492E-03 0,03930286 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 4,492E-03 0,03916046 GO:0043433|negative regulation of transcription factor activity, ! response to ionizing radiation GO:0010212 65 32 1,000 4,782E-03 0,04153344 ! peripheral nervous system development GO:0007422 64 32 1,000 4,782E-03 0,04138404 ! DNA damage checkpoint GO:0000077 71 33 1,000 5,08E-03 0,04380442 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 5,08E-03 0,04364798 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 5,386E-03 0,04611448 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,7E-03 0,04863416 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 5,7E-03 0,0484623 ! telencephalon development GO:0021537 68 35 1,000 5,7E-03 0,04829166 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,7E-03 0,04812222 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 6,023E-03 0,05066885 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 6,023E-03 0,0504923 ! DNA integrity checkpoint GO:0031570 75 36 1,000 6,023E-03 0,05031698 ! negative regulation of cell activation GO:0050866 65 36 1,000 6,023E-03 0,05014287 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,354E-03 0,05271521 ! regulation of protein stability GO:0031647 73 37 1,000 6,354E-03 0,05253406 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,693E-03 0,05514747 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,693E-03 0,05495925 ! carbohydrate homeostasis GO:0033500 53 38 1,000 6,693E-03 0,05477232 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,693E-03 0,05458665 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 7,04E-03 0,05722334 ! learning GO:0007612 77 39 1,000 7,04E-03 0,05703067 ! segmentation GO:0035282 67 39 1,000 7,04E-03 0,0568393 ! regulation of action potential in neuron GO:0019228 73 39 1,000 7,04E-03 0,0566492 ! maintenance of protein location GO:0045185 91 40 1,000 7,395E-03 0,05930809 ! gliogenesis GO:0042063 88 41 1,000 7,758E-03 0,0620129 ! regulation of T cell proliferation GO:0042129 71 41 1,000 7,758E-03 0,06180756 ! T cell differentiation GO:0030217 81 41 1,000 7,758E-03 0,06160357 ! keratinocyte differentiation GO:0030216 62 41 1,000 7,758E-03 0,06140093 ! regulation of T cell differentiation GO:0045580 70 41 1,000 7,758E-03 0,06119962 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 8,129E-03 0,06391617 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 8,129E-03 0,06370797 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 8,129E-03 0,06350113 ! double-strand break repair GO:0006302 81 44 1,000 8,894E-03 0,06925497 ! B cell differentiation GO:0030183 107 44 1,000 8,894E-03 0,06903156 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 9,289E-03 0,07186014 ! epidermal cell differentiation GO:0009913 68 46 1,000 9,691E-03 0,07472987 ! endosome transport GO:0016197 108 47 1,000 0,01010029 0,07763995 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01010029 0,07739269 ! JNK cascade GO:0007254 91 47 1,000 0,01010029 0,07714699 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,01010029 0,07690286 ! protein homooligomerization GO:0051260 76 47 1,000 0,01010029 0,07666026 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,01051751 0,07957589 ! mitochondrial transport GO:0006839 82 48 1,000 0,01051751 0,07932643 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01051751 0,07907854 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01051751 0,07883219 ! regulation of action potential GO:0001508 95 49 1,000 0,01094226 0,08176112 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01094226 0,08150799 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,01094226 0,08125642 ! regulation of ossification GO:0030278 117 50 1,000 0,01137449 0,08420623 ! histone modification GO:0016570 91 50 1,000 0,01137449 0,08394793 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01137449 0,0836912 ! positive regulation of binding GO:0051099 78 51 1,000 0,01181415 0,08666109 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,01181415 0,08639768 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,01181415 0,08613587 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01226118 0,08912507 ! positive regulation of growth GO:0045927 90 52 1,000 0,01226118 0,08885662 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01226118 0,08858978 ! synapse organization GO:0050808 85 52 1,000 0,01226118 0,08832454 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,01271554 0,09132413 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01271554 0,09105233 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,01271554 0,09078214 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01317717 0,09379961 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01317717 0,09352292 ! chloride transport GO:0006821 90 55 1,000 0,01364602 0,09656569 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01364602 0,09628251 ! aging GO:0007568 103 55 1,000 0,01364602 0,09600098 ! heart morphogenesis GO:0003007 97 55 1,000 0,01364602 0,0957211 ! RNA elongation GO:0006354 79 55 1,000 0,01364602 0,09544284 ! regulation of actin filament length GO:0030832 105 56 1,000 0,01412205 0,09848598 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01412205 0,09820134 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01412205 0,09791833 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01460521 0,10097738 ! muscle fiber development GO:0048747 112 57 1,000 0,01460521 0,10068804 ! lipid modification GO:0030258 97 57 1,000 0,01460521 0,10040036 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01460521 0,10011432 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01509543 0,10318071 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01509543 0,10288842 ! regulation of cellular component size GO:0032535 109 59 1,000 0,01559268 0,10597739 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01600152 0,10844972 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01600152 0,10814509 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01600152 0,10784216 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01600152 0,10754092 ! neuron fate determination GO:0048664 7 5 0,000 0,01600152 0,10724137 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01600152 0,10694347 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01600152 0,10664723 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01600152 0,10635263 ! polyol transport GO:0015791 12 5 0,000 0,01600152 0,10605964 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01600152 0,10576827 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01600152 0,10547849 ! response to superoxide GO:0000303 10 5 0,000 0,01600152 0,1051903 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01600152 0,10490368 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01600152 0,10461862 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01600152 0,1043351 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01600152 0,10405311 ! female meiosis GO:0007143 7 5 0,000 0,01600152 0,10377264 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01600152 0,10349368 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01600152 0,10321622 ! cobalt ion transport GO:0006824 11 5 0,000 0,01600152 0,10294024 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01600152 0,10266573 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01600152 0,10239269 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01600152 0,10212109 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01600152 0,10185093 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01600152 0,10158219 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01600152 0,10131487 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01600152 0,10104895 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01600152 0,10078443 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01600152 0,10052128 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01600152 0,10025951 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01600152 0,09999909 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01600152 0,09974003 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01600152 0,0994823 ! negative chemotaxis GO:0050919 14 5 0,000 0,01600152 0,0992259 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01600152 0,09897082 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01600152 0,09871705 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01600152 0,09846458 ! behavioral response to pain GO:0048266 9 5 0,000 0,01600152 0,09821339 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01600152 0,09796349 ! Notch receptor processing GO:0007220 8 5 0,000 0,01600152 0,09771485 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01600152 0,09746747 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01600152 0,09722134 ! micturition GO:0060073 9 5 0,000 0,01600152 0,09697645 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01600152 0,09673279 ! copulation GO:0007620 9 5 0,000 0,01600152 0,09649035 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01600152 0,09624913 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01600152 0,0960091 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01600152 0,09577027 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01600152 0,09553263 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01600152 0,09529616 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01600152 0,09506087 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01600152 0,09482673 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01600152 0,09459374 ! grooming behavior GO:0007625 6 5 0,000 0,01600152 0,09436189 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01600152 0,09413117 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01600152 0,09390159 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01600152 0,09367312 ! response to protozoan GO:0001562 10 5 0,000 0,01600152 0,09344575 ! lymph vessel development GO:0001945 10 5 0,000 0,01600152 0,09321949 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01600152 0,09299432 ! endochondral ossification GO:0001958 16 5 0,000 0,01600152 0,09277024 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01600152 0,09254724 ! parathyroid gland development GO:0060017 13 5 0,000 0,01600152 0,0923253 ! anagen GO:0042640 6 5 0,000 0,01600152 0,09210443 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01600152 0,09188461 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01600152 0,09166583 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01600152 0,0914481 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01600152 0,0912314 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01600152 0,09101572 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01600152 0,09080106 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01600152 0,09058741 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01600152 0,09037477 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01600152 0,09016312 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01600152 0,08995245 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01600152 0,08974278 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01600152 0,08953407 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01600152 0,08932634 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01600152 0,08911956 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01600152 0,08891374 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01600152 0,08870887 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01600152 0,08850494 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01600152 0,08830195 ! histidine catabolic process GO:0006548 6 5 0,000 0,01600152 0,08809989 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01600152 0,08789875 ! microvillus organization GO:0032528 7 5 0,000 0,01600152 0,08769852 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01600152 0,08749921 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01600152 0,08730079 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01600152 0,08710328 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01600152 0,08690666 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01600152 0,08671092 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01600152 0,08651607 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01600152 0,08632209 ! polyol catabolic process GO:0046174 7 5 0,000 0,01600152 0,08612897 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01600152 0,08593672 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01600152 0,08574532 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01600152 0,08555478 ! muscle cell migration GO:0014812 8 5 0,000 0,01600152 0,08536508 ! mitochondrial fission GO:0000266 8 5 0,000 0,01600152 0,08517622 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01600152 0,08498819 ! mRNA transcription GO:0009299 9 5 0,000 0,01600152 0,08480099 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01600152 0,08461462 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01600152 0,08442906 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01600152 0,08424431 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01600152 0,08406037 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01600152 0,08387723 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01600152 0,08369489 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01600152 0,08351334 ! response to food GO:0032094 6 5 0,000 0,01600152 0,08333258 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01600152 0,08315259 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01600152 0,08297338 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01600152 0,08279495 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01600152 0,08261728 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01600152 0,08244037 ! forebrain neuron development GO:0021884 13 5 0,000 0,01600152 0,08226421 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01600152 0,08208881 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01600152 0,08191415 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01600152 0,08174023 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01600152 0,08156706 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01600152 0,08139461 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01600152 0,08122289 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01600152 0,0810519 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01600152 0,08088162 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01600152 0,08071206 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01600152 0,0805432 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01600152 0,08037505 ! basic amino acid transport GO:0015802 11 5 0,000 0,01600152 0,08020761 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01600152 0,08004085 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01600152 0,07987479 ! depyrimidination GO:0045008 10 5 0,000 0,01600152 0,07970942 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01600152 0,07954473 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01600152 0,07938072 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01600152 0,07921739 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01600152 0,07905472 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01600152 0,07889273 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01600152 0,07873139 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01600152 0,07857072 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01600152 0,07841069 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01600152 0,07825132 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01600152 0,0780926 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01600152 0,07793452 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01600152 0,07777707 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01600152 0,07762026 ! response to arsenic GO:0046685 10 5 0,000 0,01600152 0,07746409 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01600152 0,07730854 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01600152 0,07715361 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01600152 0,0769993 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01600152 0,07684561 ! response to cadmium ion GO:0046686 7 5 0,000 0,01600152 0,07669253 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01600152 0,07654006 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01600152 0,0763882 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01600152 0,07623693 ! decidualization GO:0046697 11 5 0,000 0,01600152 0,07608627 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01600152 0,07593619 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01600152 0,07578671 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01600152 0,07563782 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01600152 0,07548951 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01600152 0,07534178 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01600152 0,07519463 ! neural tube patterning GO:0021532 7 5 0,000 0,01600152 0,07504805 ! embryonic cleavage GO:0040016 6 5 0,000 0,01600152 0,07490204 ! peroxisome fission GO:0016559 5 5 0,000 0,01600152 0,0747566 ! histone demethylation GO:0016577 10 5 0,000 0,01600152 0,07461173 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01600152 0,07446741 ! mitotic recombination GO:0006312 9 5 0,000 0,01600152 0,07432365 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01600152 0,07418044 ! metaphase plate congression GO:0051310 7 5 0,000 0,01600152 0,07403779 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01600152 0,07389568 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01600152 0,07375412 ! enteric nervous system development GO:0048484 8 5 0,000 0,01600152 0,0736131 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01600152 0,07347262 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01600152 0,07333267 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01600152 0,07319325 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01600152 0,07305437 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01600152 0,072916 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01600152 0,07277817 ! plasminogen activation GO:0031639 5 5 0,000 0,01600152 0,07264085 ! B cell homeostasis GO:0001782 13 5 0,000 0,01600152 0,07250405 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01600152 0,07236776 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01600152 0,07223199 ! metaphase GO:0051323 8 5 0,000 0,01600152 0,07209672 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01600152 0,07196196 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01600152 0,07182771 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01600152 0,07169395 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01600152 0,07156069 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01600152 0,07142792 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01600152 0,07129565 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01600152 0,07116386 ! response to redox state GO:0051775 5 5 0,000 0,01600152 0,07103257 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01600152 0,07090175 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01600152 0,07077142 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01600152 0,07064156 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01600152 0,07051218 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01600152 0,07038327 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01600152 0,07025484 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01600152 0,07012687 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01600152 0,06999936 ! striatum development GO:0021756 9 5 0,000 0,01600152 0,06987232 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01600152 0,06974574 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01600152 0,06961962 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01600152 0,06949395 ! glial cell migration GO:0008347 11 5 0,000 0,01600152 0,06936874 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01600152 0,06924398 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01600152 0,06911966 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01600152 0,06899579 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01600152 0,06887236 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01600152 0,06874938 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01600152 0,06862683 ! neuroprotection GO:0043526 6 5 0,000 0,01600152 0,06850472 ! neural plate development GO:0001840 8 5 0,000 0,01600152 0,06838304 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01600152 0,06826179 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01600152 0,06814097 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01600152 0,06802058 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01600152 0,06790062 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01600152 0,06778107 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01600152 0,06766195 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01600152 0,06754325 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01600152 0,06742496 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01600152 0,06730708 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01600152 0,06718962 ! spindle assembly GO:0051225 6 5 0,000 0,01600152 0,06707256 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01600152 0,06695591 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01600152 0,06683967 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01600152 0,06672383 ! drug metabolic process GO:0017144 6 5 0,000 0,01600152 0,06660839 ! stem cell division GO:0017145 11 5 0,000 0,01600152 0,06649335 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01600152 0,06637871 ! organ regeneration GO:0031100 7 5 0,000 0,01600152 0,06626446 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01600152 0,0661506 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01600152 0,06603714 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01600152 0,06592406 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,01609691 0,06620369 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01712608 0,07031631 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,01765094 0,0723478 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01917128 0,07844574 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01917128 0,07831256 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01917128 0,07817982 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01917128 0,07804754 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01917128 0,0779157 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01917128 0,07778431 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01917128 0,07765336 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01917128 0,07752285 ! sleep GO:0030431 13 6 0,000 0,01917128 0,07739278 ! response to oxygen radical GO:0000305 11 6 0,000 0,01917128 0,07726314 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01917128 0,07713394 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01917128 0,07700517 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01917128 0,07687683 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01917128 0,07674891 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01917128 0,07662142 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01917128 0,07649436 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01917128 0,07636771 ! forebrain regionalization GO:0021871 8 6 0,000 0,01917128 0,07624148 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01917128 0,07611567 ! male meiosis GO:0007140 7 6 0,000 0,01917128 0,07599027 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01917128 0,07586529 ! response to zinc ion GO:0010043 9 6 0,000 0,01917128 0,07574072 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01917128 0,07561655 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01917128 0,07549279 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01917128 0,07536944 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01917128 0,07524649 ! malate metabolic process GO:0006108 11 6 0,000 0,01917128 0,07512394 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01917128 0,07500178 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01917128 0,07488003 ! protein refolding GO:0042026 15 6 0,000 0,01917128 0,07475866 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01917128 0,0746377 ! opsonization GO:0008228 8 6 0,000 0,01917128 0,07451712 ! mating behavior GO:0007617 7 6 0,000 0,01917128 0,07439693 ! neuron remodeling GO:0016322 15 6 0,000 0,01917128 0,07427713 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01917128 0,07415771 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01917128 0,07403868 ! equilibrioception GO:0050957 14 6 0,000 0,01917128 0,07392003 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01917128 0,07380175 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01917128 0,07368386 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01917128 0,07356634 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01917128 0,0734492 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01917128 0,07333243 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01917128 0,07321603 ! toxin metabolic process GO:0009404 11 6 0,000 0,01917128 0,07309999 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01917128 0,07298433 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01917128 0,07286903 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01917128 0,07275409 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01917128 0,07263952 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01917128 0,07252531 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01917128 0,07241145 ! thymic T cell selection GO:0045061 12 6 0,000 0,01917128 0,07229796 ! protein lipoylation GO:0009249 10 6 0,000 0,01917128 0,07218481 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01917128 0,07207203 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01917128 0,07195959 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01917128 0,0718475 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01917128 0,07173576 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01917128 0,07162437 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01917128 0,07151333 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01917128 0,07140263 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01917128 0,07129227 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01917128 0,07118225 ! hyperosmotic response GO:0006972 9 6 0,000 0,01917128 0,07107257 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01917128 0,07096322 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01917128 0,07085422 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01917128 0,07074555 ! urea metabolic process GO:0019627 7 6 0,000 0,01917128 0,07063721 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01917128 0,0705292 ! neutrophil activation GO:0042119 8 6 0,000 0,01917128 0,07042152 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01917128 0,07031417 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01917128 0,07020715 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01917128 0,07010045 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01917128 0,06999408 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01917128 0,06988802 ! neuron apoptosis GO:0051402 9 6 0,000 0,01917128 0,06978229 ! nucleoside salvage GO:0043174 9 6 0,000 0,01917128 0,06967688 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01917128 0,06957179 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01917128 0,06946701 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01917128 0,06936255 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01917128 0,0692584 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01917128 0,06915457 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01917128 0,06905104 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01917128 0,06894783 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01917128 0,06884492 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01917128 0,06874232 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01917128 0,06864002 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01917128 0,06853803 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01917128 0,06843634 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01917128 0,06833496 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01917128 0,06823387 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01917128 0,06813308 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01917128 0,06803259 ! monocyte differentiation GO:0030224 12 6 0,000 0,01917128 0,0679324 ! neural nucleus development GO:0048857 14 6 0,000 0,01917128 0,06783249 ! response to UV-C GO:0010225 11 6 0,000 0,01917128 0,06773289 ! astrocyte development GO:0014002 15 6 0,000 0,01917128 0,06763357 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01917128 0,06753455 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01917128 0,06743581 ! interaction with symbiont GO:0051702 13 6 0,000 0,01917128 0,06733737 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01917128 0,06723921 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01917128 0,06714133 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01917128 0,06704374 ! response to copper ion GO:0046688 10 6 0,000 0,01917128 0,06694644 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01917128 0,06684941 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01917128 0,06675267 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01917128 0,06665621 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01917128 0,06656002 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01917128 0,06646412 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01917128 0,06636848 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01917128 0,06627313 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01917128 0,06617804 ! hair follicle maturation GO:0048820 7 6 0,000 0,01917128 0,06608323 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01917128 0,06598869 ! Schwann cell development GO:0014044 15 6 0,000 0,01917128 0,06589442 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01917128 0,06580042 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01917128 0,06570669 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01917128 0,06561322 ! subpallium development GO:0021544 10 6 0,000 0,01917128 0,06552002 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01917128 0,06542709 ! histone ubiquitination GO:0016574 8 6 0,000 0,01917128 0,06533441 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01917128 0,065242 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01917128 0,06514985 ! G2 phase GO:0051319 16 6 0,000 0,01917128 0,06505796 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01917128 0,06496633 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01917128 0,06487496 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01917128 0,06478384 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01917128 0,06469298 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01917128 0,06460238 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01917128 0,06451202 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01917128 0,06442192 ! receptor internalization GO:0031623 10 6 0,000 0,01917128 0,06433207 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01917128 0,06424247 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01917128 0,06415312 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01917128 0,06406402 ! protein deubiquitination GO:0016579 14 6 0,000 0,01917128 0,06397517 ! protein destabilization GO:0031648 9 6 0,000 0,01917128 0,06388656 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01917128 0,0637982 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01917128 0,06371008 GO:0045625|regulation of T-helper 1 cell differentiation, ! progesterone metabolic process GO:0042448 10 6 0,000 0,01917128 0,0636222 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01917128 0,06353457 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01917128 0,06344717 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01917128 0,06336002 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01917128 0,06327311 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01917128 0,06318643 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01917128 0,06309999 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01917128 0,06301379 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01917128 0,06292783 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01917128 0,06284209 ! catecholamine transport GO:0051937 9 6 0,000 0,01917128 0,06275659 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01917128 0,06267133 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01917128 0,06258629 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01917128 0,06250149 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01917128 0,06241691 ! maternal placenta development GO:0001893 12 6 0,000 0,01917128 0,06233256 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01917128 0,06224844 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01917128 0,06216455 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01917128 0,06208088 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01917128 0,06199744 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01917128 0,06191422 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01917128 0,06183123 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01917128 0,06174846 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01926599 0,06197054 ! actin filament organization GO:0007015 148 66 1,000 0,01926599 0,06188781 ! lung development GO:0030324 144 67 1,000 0,01981767 0,06357509 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,01981767 0,06349044 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01981767 0,06340601 ! regulation of lipase activity GO:0060191 130 68 1,000 0,02037595 0,06510561 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,02094076 0,06682158 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,02094076 0,06673307 ! antigen processing and presentation GO:0019882 104 69 1,000 0,02094076 0,0666448 ! respiratory tube development GO:0030323 150 70 1,000 0,02151207 0,06837257 ! amine catabolic process GO:0009310 117 71 1,000 0,02208983 0,07011625 ! B cell activation GO:0042113 160 71 1,000 0,02208983 0,07002387 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,02208983 0,06993174 ! tRNA transcription GO:0009304 14 7 0,000 0,02233093 0,07060214 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02233093 0,07050948 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02233093 0,07041707 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02233093 0,0703249 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02233093 0,07023298 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02233093 0,07014129 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02233093 0,07004984 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02233093 0,06995863 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02233093 0,06986766 ! prostate gland development GO:0030850 13 7 0,000 0,02233093 0,06977692 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02233093 0,06968642 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02233093 0,06959615 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02233093 0,06950612 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02233093 0,06941631 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02233093 0,06932674 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02233093 0,06923741 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02233093 0,0691483 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02233093 0,06905942 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02233093 0,06897077 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02233093 0,06888234 ! glycolipid transport GO:0046836 10 7 0,000 0,02233093 0,06879415 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02233093 0,06870617 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02233093 0,06861843 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02233093 0,0685309 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02233093 0,0684436 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02233093 0,06835652 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02233093 0,06826967 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02233093 0,06818303 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02233093 0,06809661 ! mRNA stabilization GO:0048255 18 7 0,000 0,02233093 0,06801041 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02233093 0,06792443 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02233093 0,06783867 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02233093 0,06775312 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02233093 0,06766779 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02233093 0,06758268 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02233093 0,06749777 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02233093 0,06741308 ! lipoprotein transport GO:0042953 14 7 0,000 0,02233093 0,06732861 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02233093 0,06724434 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02233093 0,06716028 ! rhythmic behavior GO:0007622 15 7 0,000 0,02233093 0,06707644 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02233093 0,0669928 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02233093 0,06690937 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02233093 0,06682615 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02233093 0,06674314 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02233093 0,06666033 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02233093 0,06657773 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02233093 0,06649533 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02233093 0,06641314 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02233093 0,06633114 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02233093 0,06624936 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02233093 0,06616777 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02233093 0,06608638 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02233093 0,06600519 ! spinal cord patterning GO:0021511 13 7 0,000 0,02233093 0,06592421 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02233093 0,06584342 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02233093 0,06576282 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02233093 0,06568243 ! adrenal gland development GO:0030325 17 7 0,000 0,02233093 0,06560223 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02233093 0,06552223 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02233093 0,06544242 ! ovulation GO:0030728 9 7 0,000 0,02233093 0,06536281 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02233093 0,06528339 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02233093 0,06520416 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02233093 0,06512512 ! microtubule nucleation GO:0007020 20 7 0,000 0,02233093 0,06504628 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02233093 0,06496763 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02233093 0,06488916 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02233093 0,06481089 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02233093 0,0647328 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02233093 0,06465491 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02233093 0,0645772 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02233093 0,06449967 ! galactose metabolic process GO:0006012 13 7 0,000 0,02233093 0,06442233 ! vesicle fusion GO:0006906 17 7 0,000 0,02233093 0,06434518 ! response to dietary excess GO:0002021 8 7 0,000 0,02233093 0,06426821 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02233093 0,06419143 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02233093 0,06411483 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02233093 0,06403841 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02233093 0,06396218 ! organ growth GO:0035265 15 7 0,000 0,02233093 0,06388612 ! purine salvage GO:0043101 10 7 0,000 0,02233093 0,06381025 ! nucleoside transport GO:0015858 8 7 0,000 0,02233093 0,06373455 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02233093 0,06365904 ! parturition GO:0007567 14 7 0,000 0,02233093 0,0635837 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02233093 0,06350854 ! rRNA modification GO:0000154 14 7 0,000 0,02233093 0,06343356 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02233093 0,06335876 ! spindle checkpoint GO:0031577 15 7 0,000 0,02233093 0,06328413 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02233093 0,06320968 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02233093 0,0631354 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02233093 0,0630613 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02233093 0,06298737 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02233093 0,06291362 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02233093 0,06284003 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02233093 0,06276662 ! fibrinolysis GO:0042730 10 7 0,000 0,02233093 0,06269338 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02233093 0,06262031 ! eating behavior GO:0042755 7 7 0,000 0,02233093 0,06254741 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02233093 0,06247468 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02233093 0,06240212 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02233093 0,06232973 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02233093 0,06225751 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02233093 0,06218545 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02233093 0,06211356 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02233093 0,06204183 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02233093 0,06197027 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02233093 0,06189888 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02233093 0,06182765 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02233093 0,06175658 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02233093 0,06168568 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02233093 0,06161494 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02233093 0,06154436 ! regulation of meiosis GO:0040020 12 7 0,000 0,02233093 0,06147394 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02233093 0,06140369 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02233093 0,06133359 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02233093 0,06126366 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02233093 0,06119388 ! transcription termination GO:0006353 13 7 0,000 0,02233093 0,06112426 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02233093 0,0610548 ! anaphase GO:0051322 17 7 0,000 0,02233093 0,0609855 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02233093 0,06091636 ! axonal fasciculation GO:0007413 18 7 0,000 0,02233093 0,06084737 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02233093 0,06077854 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02233093 0,06070986 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02233093 0,06064134 ! diuresis GO:0030146 12 7 0,000 0,02233093 0,06057297 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02233093 0,06050476 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02233093 0,0604367 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02233093 0,06036879 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02233093 0,06030104 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02233093 0,06023344 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02233093 0,06016599 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02233093 0,06009869 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02233093 0,06003154 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02233093 0,05996454 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02233093 0,05989769 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02233093 0,05983099 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02233093 0,05976444 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02233093 0,05969803 ! lymph node development GO:0048535 10 7 0,000 0,02233093 0,05963177 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02233093 0,05956566 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02233093 0,0594997 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02233093 0,05943388 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02233093 0,05936821 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02233093 0,05930268 ! adult feeding behavior GO:0008343 9 7 0,000 0,02233093 0,0592373 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02233093 0,05917206 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02233093 0,05910696 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02233093 0,05904201 ! muscle adaptation GO:0043500 14 7 0,000 0,02233093 0,0589772 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02233093 0,05891253 ! retina homeostasis GO:0001895 12 7 0,000 0,02233093 0,058848 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02233093 0,05878362 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02233093 0,05871937 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02233093 0,05865527 ! protein prenylation GO:0018342 18 7 0,000 0,02233093 0,05859131 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02233093 0,05852748 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02233093 0,05846379 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02233093 0,05840025 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02267398 0,05923301 ! respiratory system development GO:0060541 153 72 1,000 0,02267398 0,05916876 ! learning or memory GO:0007611 147 73 1,000 0,02326449 0,06064395 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,02386131 0,06213238 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02446439 0,06363387 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02446439 0,06356516 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02548052 0,06613389 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02548052 0,06606263 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02548052 0,06599152 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02548052 0,06592056 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02548052 0,06584975 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02548052 0,0657791 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02548052 0,0657086 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02548052 0,06563824 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02548052 0,06556804 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02548052 0,06549799 ! meiotic prophase I GO:0007128 13 8 0,000 0,02548052 0,06542809 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02548052 0,06535834 ! oligopeptide transport GO:0006857 15 8 0,000 0,02548052 0,06528873 ! UTP metabolic process GO:0046051 8 8 0,000 0,02548052 0,06521928 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02548052 0,06514997 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02548052 0,06508081 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02548052 0,06501179 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02548052 0,06494292 ! succinate metabolic process GO:0006105 14 8 0,000 0,02548052 0,0648742 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02548052 0,06480562 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02548052 0,06473719 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02548052 0,0646689 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02548052 0,06460076 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02548052 0,06453276 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02548052 0,0644649 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02548052 0,06439719 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02548052 0,06432961 ! reflex GO:0060004 16 8 0,000 0,02548052 0,06426218 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02548052 0,06419489 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02548052 0,06412774 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02548052 0,06406073 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02548052 0,06399386 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02548052 0,06392713 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02548052 0,06386054 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02548052 0,06379409 ! pigment granule organization GO:0048753 16 8 0,000 0,02548052 0,06372778 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02548052 0,0636616 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02548052 0,06359556 ! histidine metabolic process GO:0006547 16 8 0,000 0,02548052 0,06352966 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02548052 0,06346389 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02548052 0,06339826 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02548052 0,06333277 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02548052 0,06326741 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02548052 0,06320219 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02548052 0,0631371 ! melanin metabolic process GO:0006582 15 8 0,000 0,02548052 0,06307214 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02548052 0,06300732 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02548052 0,06294263 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02548052 0,06287807 ! macrophage activation GO:0042116 12 8 0,000 0,02548052 0,06281365 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02548052 0,06274936 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02548052 0,06268519 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02548052 0,06262116 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02548052 0,06255727 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02548052 0,0624935 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02548052 0,06242986 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02548052 0,06236635 ! osteoblast development GO:0002076 16 8 0,000 0,02548052 0,06230297 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02548052 0,06223972 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02548052 0,06217659 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02548052 0,0621136 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02548052 0,06205073 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02548052 0,06198799 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02548052 0,06192537 ! response to UV-B GO:0010224 16 8 0,000 0,02548052 0,06186289 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02548052 0,06180052 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02548052 0,06173829 ! intermediate filament organization GO:0045109 12 8 0,000 0,02548052 0,06167618 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02548052 0,06161419 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02548052 0,06155233 ! cellular extravasation GO:0045123 12 8 0,000 0,02548052 0,06149059 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02548052 0,06142898 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02548052 0,06136749 ! response to antibiotic GO:0046677 11 8 0,000 0,02548052 0,06130612 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02548052 0,06124488 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02548052 0,06118375 ! DNA topological change GO:0006265 12 8 0,000 0,02548052 0,06112275 ! response to tropane GO:0014073 15 8 0,000 0,02548052 0,06106187 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02548052 0,06100111 ! melanosome transport GO:0032402 13 8 0,000 0,02548052 0,06094048 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02548052 0,06087996 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02548052 0,06081956 ! mast cell activation GO:0045576 14 8 0,000 0,02548052 0,06075929 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02548052 0,06069913 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02548052 0,06063909 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02548052 0,06057917 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02548052 0,06051937 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02548052 0,06045968 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02548052 0,06040012 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02548052 0,06034067 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02548052 0,06028134 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02548052 0,06022212 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02548052 0,06016302 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02548052 0,06010404 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02548052 0,06004517 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02548052 0,05998642 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02548052 0,05992778 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02548052 0,05986926 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02548052 0,05981085 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02548052 0,05975255 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02548052 0,05969437 ! hormone catabolic process GO:0042447 17 8 0,000 0,02548052 0,0596363 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02548052 0,05957835 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02548052 0,05952051 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02548052 0,05946277 ! ATP catabolic process GO:0006200 11 8 0,000 0,02548052 0,05940516 ! blastocyst growth GO:0001832 19 8 0,000 0,02548052 0,05934765 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02548052 0,05929025 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02548052 0,05923297 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02548052 0,05917579 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02548052 0,05911873 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02548052 0,05906177 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02548052 0,05900493 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02548052 0,05894819 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02548052 0,05889157 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02548052 0,05883505 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02548052 0,05877864 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02548052 0,05872234 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02548052 0,05866614 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02548052 0,05861006 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02548052 0,05855408 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02548052 0,05849821 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02548052 0,05844244 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02548052 0,05838678 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,02568916 0,05880888 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02568916 0,05875297 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,02631076 0,06011747 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02631076 0,06006043 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,02693844 0,06143496 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02693844 0,06137678 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,02693844 0,06131872 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,02757215 0,06270189 ! inorganic anion transport GO:0015698 138 80 1,000 0,02757215 0,06264268 ! T cell activation GO:0042110 168 81 1,000 0,02821186 0,0640356 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02821186 0,06397525 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,02821186 0,06391501 ! axon extension GO:0048675 15 9 0,000 0,02862005 0,06477879 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02862005 0,06471791 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02862005 0,06465714 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02862005 0,06459648 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02862005 0,06453594 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02862005 0,06447552 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02862005 0,0644152 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02862005 0,064355 ! phosphate transport GO:0006817 19 9 0,000 0,02862005 0,06429491 ! reproductive behavior GO:0019098 19 9 0,000 0,02862005 0,06423494 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02862005 0,06417507 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02862005 0,06411532 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02862005 0,06405568 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02862005 0,06399615 ! GTP metabolic process GO:0046039 9 9 0,000 0,02862005 0,06393672 ! RNA methylation GO:0001510 15 9 0,000 0,02862005 0,06387741 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02862005 0,06381821 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02862005 0,06375912 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02862005 0,06370014 ! artery development GO:0060840 24 9 0,000 0,02862005 0,06364127 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02862005 0,0635825 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02862005 0,06352385 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02862005 0,0634653 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02862005 0,06340686 ! chemosensory behavior GO:0007635 20 9 0,000 0,02862005 0,06334853 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02862005 0,06329031 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02862005 0,06323219 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02862005 0,06317418 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02862005 0,06311627 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02862005 0,06305847 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02862005 0,06300078 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02862005 0,06294319 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02862005 0,06288571 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02862005 0,06282833 ! protein targeting to ER GO:0045047 22 9 0,000 0,02862005 0,06277106 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02862005 0,06271389 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02862005 0,06265683 ! T cell selection GO:0045058 23 9 0,000 0,02862005 0,06259987 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02862005 0,06254301 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02862005 0,06248625 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02862005 0,0624296 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02862005 0,06237305 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02862005 0,06231661 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02862005 0,06226026 ! mannose metabolic process GO:0006013 13 9 0,000 0,02862005 0,06220402 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02862005 0,06214788 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02862005 0,06209184 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02862005 0,0620359 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02862005 0,06198006 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02862005 0,06192433 ! ruffle organization GO:0031529 15 9 0,000 0,02862005 0,06186869 ! retinol metabolic process GO:0042572 18 9 0,000 0,02862005 0,06181315 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02862005 0,06175771 ! behavioral fear response GO:0001662 22 9 0,000 0,02862005 0,06170238 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02862005 0,06164714 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02862005 0,061592 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02862005 0,06153695 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02862005 0,06148201 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02862005 0,06142717 ! segment specification GO:0007379 13 9 0,000 0,02862005 0,06137242 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02862005 0,06131777 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02862005 0,06126321 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02862005 0,06120876 ! response to amine stimulus GO:0014075 13 9 0,000 0,02862005 0,0611544 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02862005 0,06110013 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02862005 0,06104597 ! erythrocyte development GO:0048821 15 9 0,000 0,02862005 0,0609919 ! gas homeostasis GO:0033483 16 9 0,000 0,02862005 0,06093792 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02862005 0,06088404 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02862005 0,06083026 ! renal water homeostasis GO:0003091 14 9 0,000 0,02862005 0,06077657 ! postreplication repair GO:0006301 22 9 0,000 0,02862005 0,06072297 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02862005 0,06066947 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02862005 0,06061607 ! icosanoid secretion GO:0032309 15 9 0,000 0,02862005 0,06056275 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02862005 0,06050954 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02862005 0,06045641 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02862005 0,06040338 ! regulation of cell division GO:0051302 15 9 0,000 0,02862005 0,06035044 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02862005 0,06029759 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02862005 0,06024484 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02862005 0,06019218 ! sterol catabolic process GO:0016127 11 9 0,000 0,02862005 0,06013961 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02862005 0,06008713 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02862005 0,06003474 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02862005 0,05998245 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02862005 0,05993025 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02862005 0,05987813 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02862005 0,05982611 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02862005 0,05977418 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02862005 0,05972233 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02862005 0,05967058 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02862005 0,05961892 ! purine base metabolic process GO:0006144 21 9 0,000 0,02862005 0,05956735 ! pigment granule transport GO:0051904 17 9 0,000 0,02862005 0,05951586 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02862005 0,05946447 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02862005 0,05941316 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02862005 0,05936194 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02862005 0,05931081 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02862005 0,05925977 ! mitochondrion localization GO:0051646 15 9 0,000 0,02862005 0,05920882 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,02885752 0,05964878 ! response to drug GO:0042493 143 82 1,000 0,02885752 0,05959758 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,02885752 0,05954647 ! response to oxygen levels GO:0070482 176 83 1,000 0,02950907 0,06083876 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02950907 0,06078667 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,03016649 0,06208775 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,03016649 0,06203468 ! nucleosome assembly GO:0006334 122 85 1,000 0,03082973 0,06334442 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,03082973 0,06329037 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,03149873 0,06460865 ! mitochondrion organization GO:0007005 148 86 1,000 0,03149873 0,06455362 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03174958 0,06501234 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03174958 0,06495706 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03174958 0,06490187 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03174958 0,06484677 ! synapsis GO:0007129 13 10 0,000 0,03174958 0,06479177 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03174958 0,06473686 ! N-glycan processing GO:0006491 20 10 0,000 0,03174958 0,06468205 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03174958 0,06462733 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03174958 0,0645727 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03174958 0,06451816 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03174958 0,06446371 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03174958 0,06440936 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03174958 0,0643551 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03174958 0,06430092 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03174958 0,06424684 ! androgen metabolic process GO:0008209 17 10 0,000 0,03174958 0,06419286 ! phospholipid efflux GO:0033700 16 10 0,000 0,03174958 0,06413896 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03174958 0,06408515 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03174958 0,06403143 ! lung alveolus development GO:0048286 26 10 0,000 0,03174958 0,0639778 ! pathogenesis GO:0009405 13 10 0,000 0,03174958 0,06392427 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03174958 0,06387082 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03174958 0,06381746 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03174958 0,06376419 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03174958 0,06371101 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03174958 0,06365792 ! endoderm development GO:0007492 16 10 0,000 0,03174958 0,06360491 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03174958 0,063552 ! arginine catabolic process GO:0006527 13 10 0,000 0,03174958 0,06349917 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03174958 0,06344643 ! proline metabolic process GO:0006560 13 10 0,000 0,03174958 0,06339377 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03174958 0,06334121 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03174958 0,06328873 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03174958 0,06323634 ! V(D)J recombination GO:0033151 28 10 0,000 0,03174958 0,06318404 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03174958 0,06313182 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03174958 0,06307968 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03174958 0,06302764 ! B cell proliferation GO:0042100 18 10 0,000 0,03174958 0,06297568 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03174958 0,0629238 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03174958 0,06287202 ! multicellular organism growth GO:0035264 18 10 0,000 0,03174958 0,06282031 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03174958 0,06276869 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03174958 0,06271716 ! epithelial cell development GO:0002064 20 10 0,000 0,03174958 0,06266571 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03174958 0,06261434 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03174958 0,06256306 ! macroautophagy GO:0016236 17 10 0,000 0,03174958 0,06251186 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03174958 0,06246075 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03174958 0,06240972 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03174958 0,06235877 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03174958 0,06230791 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03174958 0,06225713 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03174958 0,06220643 ! brain morphogenesis GO:0048854 23 10 0,000 0,03174958 0,06215582 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03174958 0,06210528 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03174958 0,06205483 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03174958 0,06200446 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03174958 0,06195418 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03174958 0,06190397 ! response to dsRNA GO:0043331 20 10 0,000 0,03174958 0,06185384 ! DNA ligation GO:0006266 19 10 0,000 0,03174958 0,0618038 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03174958 0,06175384 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03174958 0,06170396 ! melanosome localization GO:0032400 16 10 0,000 0,03174958 0,06165416 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03174958 0,06160443 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03174958 0,06155479 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03174958 0,06150523 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03174958 0,06145575 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03174958 0,06140635 ! mRNA cleavage GO:0006379 17 10 0,000 0,03174958 0,06135703 ! protein sumoylation GO:0016925 15 10 0,000 0,03174958 0,06130778 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03174958 0,06125862 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03174958 0,06120953 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03174958 0,06116053 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03174958 0,0611116 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03174958 0,06106275 ! salivary gland development GO:0007431 27 10 0,000 0,03174958 0,06101398 ! prophase GO:0051324 15 10 0,000 0,03174958 0,06096528 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03174958 0,06091667 ! apical protein localization GO:0045176 15 10 0,000 0,03174958 0,06086813 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03174958 0,06081966 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03174958 0,06077128 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03174958 0,06072297 ! midbrain development GO:0030901 13 10 0,000 0,03174958 0,06067474 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03174958 0,06062659 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03174958 0,06057851 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03174958 0,06053051 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03174958 0,06048258 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03174958 0,06043473 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03174958 0,06038696 ! detection of calcium ion GO:0005513 23 10 0,000 0,03174958 0,06033926 ! oocyte development GO:0048599 17 10 0,000 0,03174958 0,06029163 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03174958 0,06024408 ! blastocyst formation GO:0001825 17 10 0,000 0,03174958 0,06019661 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03174958 0,06014921 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03174958 0,06010189 ! activation of innate immune response GO:0002218 12 10 0,000 0,03174958 0,06005464 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03174958 0,06000746 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03174958 0,05996036 ! response to nicotine GO:0035094 20 10 0,000 0,03174958 0,05991333 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03174958 0,05986638 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03174958 0,0598195 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03174958 0,05977269 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,03217347 0,06052335 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,03217347 0,06047607 ! gland development GO:0048732 206 88 1,000 0,03285389 0,06170684 ! regulation of neurological system process GO:0031644 148 88 1,000 0,03285389 0,06165871 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,03423162 0,0641943 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,03423162 0,0641443 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03486913 0,06528804 ! respiratory burst GO:0045730 17 11 0,000 0,03486913 0,06523728 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03486913 0,06518659 ! neuron fate specification GO:0048665 17 11 0,000 0,03486913 0,06513597 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03486913 0,06508544 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03486913 0,06503499 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03486913 0,06498461 ! thyroid gland development GO:0030878 26 11 0,000 0,03486913 0,06493432 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03486913 0,0648841 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03486913 0,06483395 ! response to pain GO:0048265 24 11 0,000 0,03486913 0,06478389 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03486913 0,0647339 ! T cell proliferation GO:0042098 26 11 0,000 0,03486913 0,06468399 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03486913 0,06463416 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03486913 0,0645844 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03486913 0,06453472 ! bone resorption GO:0045453 16 11 0,000 0,03486913 0,06448512 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03486913 0,06443559 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03486913 0,06438614 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03486913 0,06433676 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03486913 0,06428746 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03486913 0,06423824 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03486913 0,06418909 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03486913 0,06414001 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03486913 0,06409101 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03486913 0,06404209 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03486913 0,06399324 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03486913 0,06394446 ! UV protection GO:0009650 19 11 0,000 0,03486913 0,06389576 ! adult heart development GO:0007512 14 11 0,000 0,03486913 0,06384714 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03486913 0,06379858 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03486913 0,0637501 ! temperature homeostasis GO:0001659 17 11 0,000 0,03486913 0,0637017 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03486913 0,06365337 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03486913 0,06360511 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03486913 0,06355692 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03486913 0,06350881 ! regulation of organ growth GO:0046620 13 11 0,000 0,03486913 0,06346077 ! pigment granule localization GO:0051875 20 11 0,000 0,03486913 0,0634128 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03486913 0,06336491 ! vasoconstriction GO:0042310 18 11 0,000 0,03486913 0,06331708 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03486913 0,06326933 ! embryonic axis specification GO:0000578 18 11 0,000 0,03486913 0,06322165 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03486913 0,06317405 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03486913 0,06312651 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03486913 0,06307905 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03486913 0,06303166 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03486913 0,06298434 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03486913 0,06293709 ! zymogen activation GO:0031638 15 11 0,000 0,03486913 0,06288991 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03486913 0,0628428 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03486913 0,06279576 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03486913 0,06274879 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03486913 0,0627019 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03486913 0,06265507 ! acid secretion GO:0046717 18 11 0,000 0,03486913 0,06260831 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03486913 0,06256162 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03486913 0,062515 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03486913 0,06246846 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03486913 0,06242198 ! oocyte differentiation GO:0009994 18 11 0,000 0,03486913 0,06237557 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03486913 0,06232922 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03486913 0,06228295 ! cholesterol efflux GO:0033344 19 11 0,000 0,03486913 0,06223675 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03486913 0,06219061 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03486913 0,06214454 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03486913 0,06209855 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03486913 0,06205262 ! embryonic gut development GO:0048566 15 11 0,000 0,03486913 0,06200675 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03486913 0,06196096 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03486913 0,06191523 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03486913 0,06186957 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03486913 0,06182398 ! defense response to fungus GO:0050832 13 11 0,000 0,03486913 0,06177845 ! developmental induction GO:0031128 19 11 0,000 0,03486913 0,06173299 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03486913 0,0616876 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03486913 0,06164227 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03486913 0,06159702 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03486913 0,06155182 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03486913 0,0615067 ! nucleosome organization GO:0034728 138 92 1,000 0,03563159 0,06280557 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,03633981 0,06400701 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03633981 0,06396019 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03705346 0,06516858 ! forebrain development GO:0030900 188 95 1,000 0,0377725 0,06638468 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03797874 0,06669842 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03797874 0,06664977 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03797874 0,06660119 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03797874 0,06655269 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03797874 0,06650425 ! cartilage condensation GO:0001502 20 12 0,000 0,03797874 0,06645588 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03797874 0,06640759 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03797874 0,06635936 ! protein complex disassembly GO:0043241 27 12 0,000 0,03797874 0,0663112 GO:0043624|cellular protein complex disassembly, ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03797874 0,06626312 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03797874 0,0662151 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03797874 0,06616715 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03797874 0,06611928 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03797874 0,06607147 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03797874 0,06602373 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03797874 0,06597606 ! drug transport GO:0015893 16 12 0,000 0,03797874 0,06592846 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03797874 0,06588092 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03797874 0,06583346 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03797874 0,06578606 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03797874 0,06573873 ! focal adhesion formation GO:0048041 35 12 0,000 0,03797874 0,06569147 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03797874 0,06564428 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03797874 0,06559716 ! forebrain cell migration GO:0021885 21 12 0,000 0,03797874 0,0655501 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03797874 0,06550311 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03797874 0,06545619 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03797874 0,06540933 ! fear response GO:0042596 26 12 0,000 0,03797874 0,06536255 ! monoamine transport GO:0015844 18 12 0,000 0,03797874 0,06531583 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03797874 0,06526917 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03797874 0,06522258 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03797874 0,06517606 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03797874 0,06512961 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03797874 0,06508322 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03797874 0,0650369 ! protein homotetramerization GO:0051289 21 12 0,000 0,03797874 0,06499064 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03797874 0,06494445 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03797874 0,06489832 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03797874 0,06485226 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03797874 0,06480627 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03797874 0,06476034 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03797874 0,06471448 ! cranial nerve development GO:0021545 20 12 0,000 0,03797874 0,06466868 ! fucose catabolic process GO:0019317 22 12 0,000 0,03797874 0,06462294 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03797874 0,06457727 ! histone methylation GO:0016571 26 12 0,000 0,03797874 0,06453167 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03797874 0,06448613 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03797874 0,06444065 ! gland morphogenesis GO:0022612 29 12 0,000 0,03797874 0,06439524 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03797874 0,06434989 ! T cell homeostasis GO:0043029 25 12 0,000 0,03797874 0,0643046 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03797874 0,06425938 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03797874 0,06421422 ! spleen development GO:0048536 22 12 0,000 0,03797874 0,06416913 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03797874 0,0641241 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03797874 0,06407913 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03797874 0,06403423 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03797874 0,06398938 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03797874 0,0639446 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03797874 0,06389989 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03797874 0,06385523 ! response to cold GO:0009409 17 12 0,000 0,03797874 0,06381064 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03797874 0,06376611 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03797874 0,06372165 ! protein ubiquitination GO:0016567 217 97 1,000 0,03922659 0,06576946 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,03996156 0,06695509 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,04070175 0,06814781 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04107842 0,06873066 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04107842 0,06868289 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04107842 0,0686352 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04107842 0,06858757 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04107842 0,06854 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04107842 0,06849251 ! lipid localization GO:0010876 28 13 0,000 0,04107842 0,06844507 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04107842 0,06839771 ! organelle fusion GO:0048284 32 13 0,000 0,04107842 0,0683504 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04107842 0,06830317 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04107842 0,068256 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04107842 0,06820889 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04107842 0,06816185 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04107842 0,06811488 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04107842 0,06806796 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04107842 0,06802112 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04107842 0,06797434 ! methionine metabolic process GO:0006555 27 13 0,000 0,04107842 0,06792762 ! plasma membrane organization GO:0007009 24 13 0,000 0,04107842 0,06788097 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04107842 0,06783438 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04107842 0,06778785 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04107842 0,06774139 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04107842 0,06769499 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04107842 0,06764866 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04107842 0,06760238 ! exocrine system development GO:0035272 32 13 0,000 0,04107842 0,06755618 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04107842 0,06751003 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04107842 0,06746395 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04107842 0,06741793 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04107842 0,06737197 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04107842 0,06732608 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04107842 0,06728025 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04107842 0,06723448 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04107842 0,06718877 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04107842 0,06714313 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04107842 0,06709755 ! ribosome assembly GO:0042255 17 13 0,000 0,04107842 0,06705203 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04107842 0,06700657 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04107842 0,06696117 ! chromatin silencing GO:0006342 26 13 0,000 0,04107842 0,06691583 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04107842 0,06687056 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04107842 0,06682534 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04107842 0,06678019 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04107842 0,0667351 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04107842 0,06669007 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04107842 0,0666451 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04107842 0,06660019 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04107842 0,06655534 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04107842 0,06651056 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04107842 0,06646583 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04107842 0,06642116 ! embryonic placenta development GO:0001892 23 13 0,000 0,04107842 0,06637655 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04107842 0,066332 ! insulin secretion GO:0030073 23 13 0,000 0,04107842 0,06628752 ! actin filament polymerization GO:0030041 24 13 0,000 0,04107842 0,06624309 ! acrosome reaction GO:0007340 18 13 0,000 0,04107842 0,06619872 ! rRNA transcription GO:0009303 25 14 0,000 0,04416822 0,07113035 ! lactation GO:0007595 26 14 0,000 0,04416822 0,07108277 ! reproductive cellular process GO:0048610 20 14 0,000 0,04416822 0,07103526 ! tRNA modification GO:0006400 20 14 0,000 0,04416822 0,07098781 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04416822 0,07094042 ! regulation of S phase GO:0033261 23 14 0,000 0,04416822 0,07089309 ! water transport GO:0006833 21 14 0,000 0,04416822 0,07084583 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04416822 0,07079863 ! non-recombinational repair GO:0000726 25 14 0,000 0,04416822 0,0707515 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04416822 0,07070442 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04416822 0,07065741 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04416822 0,07061046 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04416822 0,07056358 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04416822 0,07051675 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04416822 0,07046999 ! palate development GO:0060021 31 14 0,000 0,04416822 0,07042329 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04416822 0,07037665 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04416822 0,07033008 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04416822 0,07028356 ! arginine metabolic process GO:0006525 17 14 0,000 0,04416822 0,07023711 ! regulation of heart rate GO:0002027 24 14 0,000 0,04416822 0,07019072 ! organic alcohol transport GO:0015850 29 14 0,000 0,04416822 0,07014439 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04416822 0,07009812 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04416822 0,07005191 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04416822 0,07000576 ! L-amino acid transport GO:0015807 30 14 0,000 0,04416822 0,06995968 ! stem cell development GO:0048864 43 14 0,000 0,04416822 0,06991365 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04416822 0,06986768 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04416822 0,06982178 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04416822 0,06977593 ! cerebellum development GO:0021549 21 14 0,000 0,04416822 0,06973015 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04416822 0,06968443 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04416822 0,06963876 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04416822 0,06959316 ! cofactor transport GO:0051181 26 14 0,000 0,04416822 0,06954761 ! NADP metabolic process GO:0006739 24 14 0,000 0,04416822 0,06950212 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04416822 0,0694567 ! intestinal absorption GO:0050892 25 14 0,000 0,04416822 0,06941133 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04416822 0,06936602 ! oxygen transport GO:0015671 21 14 0,000 0,04416822 0,06932078 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04416822 0,06927559 ! male genitalia development GO:0030539 24 14 0,000 0,04416822 0,06923045 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04416822 0,06918538 ! regulation of axon extension GO:0030516 37 14 0,000 0,04416822 0,06914037 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04416822 0,06909541 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04724817 0,07386556 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04724817 0,0738176 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04724817 0,0737697 ! superoxide anion generation GO:0042554 20 15 0,000 0,04724817 0,07372186 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04724817 0,07367408 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04724817 0,07362636 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04724817 0,07357871 ! copper ion transport GO:0006825 20 15 0,000 0,04724817 0,07353111 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04724817 0,07348358 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04724817 0,07343611 ! sulfate transport GO:0008272 23 15 0,000 0,04724817 0,0733887 ! response to cAMP GO:0051591 22 15 0,000 0,04724817 0,07334136 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04724817 0,07329407 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04724817 0,07324685 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04724817 0,07319968 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04724817 0,07315258 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04724817 0,07310553 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04724817 0,07305855 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04724817 0,07301163 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04724817 0,07296476 ! pituitary gland development GO:0021983 29 15 0,000 0,04724817 0,07291796 ! vesicle coating GO:0006901 33 15 0,000 0,04724817 0,07287122 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04724817 0,07282454 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04724817 0,07277792 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04724817 0,07273135 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04724817 0,07268485 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04724817 0,0726384 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04724817 0,07259202 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04724817 0,07254569 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04724817 0,07249943 ! histone deacetylation GO:0016575 20 15 0,000 0,04724817 0,07245322 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04724817 0,07240707 ! tissue regeneration GO:0042246 26 15 0,000 0,04724817 0,07236098 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04724817 0,07231495 ! water homeostasis GO:0030104 27 15 0,000 0,04724817 0,07226898 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04724817 0,07222306 ! muscle maintenance GO:0046716 26 15 0,000 0,04724817 0,07217721 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04724817 0,07213141 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04724817 0,07208567 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04724817 0,07203999 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04724817 0,07199437 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04724817 0,0719488 ! cell killing GO:0001906 29 15 0,000 0,04724817 0,07190329 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04724817 0,07185784 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04724817 0,07181245 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04724817 0,07176711 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04724817 0,07172183 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04724817 0,07167661 ! peptide hormone processing GO:0016486 23 15 0,000 0,04724817 0,07163145 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0503183 0,07623793 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0503183 0,07618995 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0503183 0,07614203 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0503183 0,07609417 ! bone remodeling GO:0046849 27 16 0,000 0,0503183 0,07604637 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0503183 0,07599864 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0503183 0,07595096 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0503183 0,07590334 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0503183 0,07585578 ! startle response GO:0001964 28 16 0,000 0,0503183 0,07580828 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0503183 0,07576084 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0503183 0,07571346 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0503183 0,07566614 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0503183 0,07561888 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0503183 0,07557168 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0503183 0,07552453 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0503183 0,07547745 ! response to osmotic stress GO:0006970 25 16 0,000 0,0503183 0,07543042 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0503183 0,07538345 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0503183 0,07533654 ! fructose metabolic process GO:0006000 25 16 0,000 0,0503183 0,07528969 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0503183 0,0752429 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0503183 0,07519617 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0503183 0,07514949 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0503183 0,07510287 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0503183 0,07505631 ! axon cargo transport GO:0008088 43 16 0,000 0,0503183 0,07500981 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0503183 0,07496336 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0503183 0,07491697 ! DNA replication initiation GO:0006270 27 16 0,000 0,0503183 0,07487064 ! neuron recognition GO:0008038 35 16 0,000 0,0503183 0,07482437 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0503183 0,07477815 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0503183 0,07473199 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0503183 0,07468589 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0503183 0,07463984 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0503183 0,07459385 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0503183 0,07454792 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0503183 0,07450205 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0503183 0,07445623 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0503183 0,07441046 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0503183 0,07436476 ! defense response to virus GO:0051607 37 16 0,000 0,0503183 0,07431911 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05337863 0,07879079 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05337863 0,07874248 ! metencephalon development GO:0022037 30 17 0,000 0,05337863 0,07869423 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05337863 0,07864604 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05337863 0,07859791 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05337863 0,07854984 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05337863 0,07850183 ! endothelial cell migration GO:0043542 28 17 0,000 0,05337863 0,07845387 ! inositol metabolic process GO:0006020 28 17 0,000 0,05337863 0,07840598 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05337863 0,07835814 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05337863 0,07831036 ! glial cell development GO:0021782 27 17 0,000 0,05337863 0,07826264 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05337863 0,07821498 ! adult walking behavior GO:0007628 33 17 0,000 0,05337863 0,07816737 ! heart looping GO:0001947 30 17 0,000 0,05337863 0,07811982 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05337863 0,07807233 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05337863 0,0780249 ! myoblast differentiation GO:0045445 45 17 0,000 0,05337863 0,07797753 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05337863 0,07793021 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05337863 0,07788295 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05337863 0,07783575 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05337863 0,07778861 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05337863 0,07774152 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05337863 0,07769449 ! NAD metabolic process GO:0019674 29 17 0,000 0,05337863 0,07764752 ! membrane budding GO:0006900 37 17 0,000 0,05337863 0,0776006 ! DNA integration GO:0015074 29 17 0,000 0,05337863 0,07755374 ! regulation of protein binding GO:0043393 33 17 0,000 0,05337863 0,07750693 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05337863 0,07746019 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05337863 0,0774135 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05337863 0,07736686 ! genitalia development GO:0048806 30 17 0,000 0,05337863 0,07732028 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05337863 0,07727376 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05337863 0,07722729 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05337863 0,07718088 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05337863 0,07713453 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05337863 0,07708823 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05337863 0,07704199 ! steroid catabolic process GO:0006706 31 17 0,000 0,05337863 0,0769958 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05337863 0,07694967 ! gas transport GO:0015669 25 17 0,000 0,05337863 0,07690359 ! organic cation transport GO:0015695 31 17 0,000 0,05337863 0,07685756 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05337863 0,0768116 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05337863 0,07676568 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05337863 0,07671983 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05337863 0,07667402 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05337863 0,07662828 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05642921 0,08095926 ! neuron maturation GO:0042551 42 18 0,000 0,05642921 0,08091101 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05642921 0,08086282 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05642921 0,08081469 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05642921 0,08076661 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05642921 0,08071859 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05642921 0,08067063 ! memory GO:0007613 31 18 0,000 0,05642921 0,08062273 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05642921 0,08057488 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05642921 0,08052709 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05642921 0,08047935 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05642921 0,08043168 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05642921 0,08038406 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05642921 0,08033649 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05642921 0,08028898 ! response to retinoic acid GO:0032526 26 18 0,000 0,05642921 0,08024153 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05642921 0,08019414 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05642921 0,0801468 ! response to fungus GO:0009620 21 18 0,000 0,05642921 0,08009951 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05642921 0,08005228 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05642921 0,08000511 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05642921 0,07995799 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05642921 0,07991093 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05642921 0,07986392 ! vitamin transport GO:0051180 27 18 0,000 0,05642921 0,07981697 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05642921 0,07977008 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05642921 0,07972324 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05642921 0,07967645 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05642921 0,07962972 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05642921 0,07958304 ! nerve development GO:0021675 28 18 0,000 0,05642921 0,07953642 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05642921 0,07948985 ! protein secretion GO:0009306 39 19 0,000 0,05947005 0,08372437 ! positive regulation of translation GO:0045727 30 19 0,000 0,05947005 0,0836754 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05947005 0,0836265 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05947005 0,08357765 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05947005 0,08352886 ! skin development GO:0043588 36 19 0,000 0,05947005 0,08348013 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05947005 0,08343145 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05947005 0,08338283 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05947005 0,08333427 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05947005 0,08328576 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05947005 0,08323731 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05947005 0,08318892 ! cerebral cortex development GO:0021987 36 19 0,000 0,05947005 0,08314058 ! pigmentation during development GO:0048066 41 19 0,000 0,05947005 0,0830923 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05947005 0,08304408 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05947005 0,08299591 ! heme metabolic process GO:0042168 36 19 0,000 0,05947005 0,08294779 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05947005 0,08289973 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05947005 0,08285173 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05947005 0,08280379 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05947005 0,0827559 ! peptide cross-linking GO:0018149 37 19 0,000 0,05947005 0,08270806 ! protein export from nucleus GO:0006611 36 19 0,000 0,05947005 0,08266028 ! heart process GO:0003015 30 19 0,000 0,05947005 0,08261255 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05947005 0,08256488 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05947005 0,08251727 ! visual learning GO:0008542 36 19 0,000 0,05947005 0,08246971 ! cellular pigmentation GO:0033059 36 19 0,000 0,05947005 0,0824222 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05947005 0,08237475 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05947005 0,08232735 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05947005 0,08228001 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05947005 0,08223273 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05947005 0,08218549 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05947005 0,08213831 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05947005 0,08209119 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05947005 0,08204412 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05947005 0,0819971 ! cilium assembly GO:0042384 37 19 0,000 0,05947005 0,08195014 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05947005 0,08190323 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0625012 0,08602853 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0625012 0,08597935 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0625012 0,08593022 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0625012 0,08588114 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0625012 0,08583212 ! response to vitamin GO:0033273 31 20 0,000 0,0625012 0,08578316 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0625012 0,08573425 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0625012 0,0856854 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0625012 0,0856366 ! response to alkaloid GO:0043279 38 20 0,000 0,0625012 0,08558786 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0625012 0,08553918 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0625012 0,08549055 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0625012 0,08544198 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0625012 0,08539346 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0625012 0,08534499 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0625012 0,08529658 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0625012 0,08524823 ! body fluid secretion GO:0007589 31 20 0,000 0,0625012 0,08519993 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0625012 0,08515169 ! peptide secretion GO:0002790 35 20 0,000 0,0625012 0,0851035 ! stem cell differentiation GO:0048863 53 20 0,000 0,0625012 0,08505536 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0625012 0,08500728 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0625012 0,08495925 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0625012 0,08491128 ! sensory perception of pain GO:0019233 30 20 0,000 0,0625012 0,08486336 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0625012 0,0848155 ! diencephalon development GO:0021536 34 20 0,000 0,0625012 0,08476769 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0625012 0,08471993 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0625012 0,08467223 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0625012 0,08462458 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0625012 0,08457698 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0625012 0,08452944 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0625012 0,08448195 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0625012 0,08443452 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0625012 0,08438714 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0625012 0,08433981 ! regulation of glucose import GO:0046324 29 20 0,000 0,0625012 0,08429253 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0625012 0,08424531 ! actin filament-based movement GO:0030048 43 20 0,000 0,0625012 0,08419814 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0625012 0,08415102 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0625012 0,08410396 ! negative regulation of translation GO:0017148 29 20 0,000 0,0625012 0,08405695 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0625012 0,08400999 ! regulation of cell killing GO:0031341 42 21 0,000 0,06552267 0,08802208 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06552267 0,08797296 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06552267 0,0879239 ! hormone secretion GO:0046879 38 21 0,000 0,06552267 0,08787489 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06552267 0,08782593 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06552267 0,08777703 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06552267 0,08772819 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06552267 0,08767939 ! axis specification GO:0009798 38 21 0,000 0,06552267 0,08763066 ! ovarian follicle development GO:0001541 35 21 0,000 0,06552267 0,08758197 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06552267 0,08753334 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06552267 0,08748477 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06552267 0,08743625 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06552267 0,08738778 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06552267 0,08733936 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06552267 0,087291 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06552267 0,0872427 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06552267 0,08719444 ! cytolysis GO:0019835 24 21 0,000 0,06552267 0,08714624 ! vasodilation GO:0042311 39 21 0,000 0,06552267 0,08709809 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06552267 0,08705 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06552267 0,08700196 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06552267 0,08695397 ! oogenesis GO:0048477 36 21 0,000 0,06552267 0,08690604 ! DNA modification GO:0006304 34 21 0,000 0,06552267 0,08685815 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06552267 0,08681033 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,06552267 0,08676255 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06552267 0,08671482 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06552267 0,08666715 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06552267 0,08661953 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06552267 0,08657197 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06552267 0,08652445 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06552267 0,08647699 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06552267 0,08642958 ! collagen catabolic process GO:0030574 28 21 0,000 0,06552267 0,08638222 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06552267 0,08633491 ! gut development GO:0048565 39 21 0,000 0,06552267 0,08628766 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06853451 0,09020461 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06853451 0,0901553 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06853451 0,09010603 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06853451 0,09005682 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06853451 0,09000766 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06853451 0,08995856 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06853451 0,08990951 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06853451 0,08986051 ! regeneration GO:0031099 41 22 0,000 0,06853451 0,08981157 ! keratinization GO:0031424 28 22 0,000 0,06853451 0,08976268 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06853451 0,08971384 ! sensory perception of taste GO:0050909 28 22 0,000 0,06853451 0,08966505 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06853451 0,08961632 ! vacuolar transport GO:0007034 36 22 0,000 0,06853451 0,08956765 ! lysosome organization GO:0007040 41 22 0,000 0,06853451 0,08951902 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06853451 0,08947045 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06853451 0,08942193 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06853451 0,08937346 ! fucose metabolic process GO:0006004 39 22 0,000 0,06853451 0,08932505 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06853451 0,08927668 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06853451 0,08922837 ! ureteric bud development GO:0001657 43 22 0,000 0,06853451 0,08918012 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06853451 0,08913191 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06853451 0,08908376 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06853451 0,08903566 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06853451 0,08898761 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06853451 0,08893961 ! sarcomere organization GO:0045214 30 22 0,000 0,06853451 0,08889166 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06853451 0,08884377 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06853451 0,08879593 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06853451 0,08874813 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06853451 0,0887004 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07153674 0,09253624 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07153674 0,09248651 ! gluconeogenesis GO:0006094 33 23 0,000 0,07153674 0,09243684 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07153674 0,09238723 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07153674 0,09233766 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07153674 0,09228815 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07153674 0,09223869 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07153674 0,09218929 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07153674 0,09213994 ! visual behavior GO:0007632 42 23 0,000 0,07153674 0,09209064 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07153674 0,09204139 ! response to ethanol GO:0045471 46 23 0,000 0,07153674 0,0919922 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07153674 0,09194306 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07153674 0,09189397 ! peroxisome organization GO:0007031 37 23 0,000 0,07153674 0,09184493 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07153674 0,09179595 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07153674 0,09174702 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07153674 0,09169814 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07153674 0,09164931 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07153674 0,09160053 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07153674 0,09155181 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07153674 0,09150314 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07153674 0,09145452 ! fatty acid transport GO:0015908 44 23 0,000 0,07153674 0,09140595 ! platelet activation GO:0030168 37 23 0,000 0,07153674 0,09135743 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07153674 0,09130897 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07153674 0,09126055 ! hormone transport GO:0009914 40 23 0,000 0,07153674 0,09121219 ! cell-cell recognition GO:0009988 25 23 0,000 0,07153674 0,09116388 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07153674 0,09111562 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07153674 0,09106741 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07153674 0,09101925 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07153674 0,09097114 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0745294 0,09472675 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,0745294 0,09467673 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0745294 0,09462677 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0745294 0,09457686 ! vesicle docking GO:0048278 47 24 0,000 0,0745294 0,09452701 ! spinal cord development GO:0021510 47 24 0,000 0,0745294 0,0944772 ! vacuole organization GO:0007033 43 24 0,000 0,0745294 0,09442745 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0745294 0,09437775 ! digestive system process GO:0022600 39 24 0,000 0,0745294 0,09432811 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0745294 0,09427851 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0745294 0,09422897 ! regulation of behavior GO:0050795 43 24 0,000 0,0745294 0,09417948 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0745294 0,09413004 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0745294 0,09408066 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0745294 0,09403132 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0745294 0,09398204 ! membrane depolarization GO:0051899 39 24 0,000 0,0745294 0,09393281 ! pentose metabolic process GO:0019321 35 24 0,000 0,0745294 0,09388363 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,0745294 0,0938345 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0745294 0,09378542 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0745294 0,0937364 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0745294 0,09368742 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0745294 0,0936385 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0745294 0,09358963 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0745294 0,09354081 ! regulation of amine transport GO:0051952 40 24 0,000 0,0745294 0,09349204 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0775125 0,09718347 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0775125 0,09713286 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0775125 0,09708229 ! phototransduction GO:0007602 33 25 0,000 0,0775125 0,09703178 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0775125 0,09698132 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,0775125 0,09693092 ! sperm motility GO:0030317 31 25 0,000 0,0775125 0,09688056 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0775125 0,09683026 ! chromosome condensation GO:0030261 45 25 0,000 0,0775125 0,09678001 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0775125 0,09672982 ! neural crest cell development GO:0014032 54 25 0,000 0,0775125 0,09667967 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0775125 0,09662958 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0775125 0,09657954 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0775125 0,09652955 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0775125 0,09647961 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0775125 0,09642972 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0775125 0,09637989 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,0775125 0,09633011 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0775125 0,09628037 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0775125 0,09623069 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,0775125 0,09618107 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0775125 0,09613149 ! telomere organization GO:0032200 43 25 0,000 0,0775125 0,09608196 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0775125 0,09603248 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0775125 0,09598306 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08048609 0,09961396 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08048609 0,09956275 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08048609 0,09951159 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08048609 0,09946047 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08048609 0,09940942 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08048609 0,09935841 ! molting cycle process GO:0022404 50 26 0,000 0,08048609 0,09930746 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,08048609 0,09925656 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08048609 0,09920571 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,08048609 0,09915491 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,08048609 0,09910417 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,08048609 0,09905348 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,08048609 0,09900283 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08048609 0,09895225 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08048609 0,09890171 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08048609 0,09885122 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,08048609 0,09880079 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08048609 0,09875041 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08048609 0,09870007 ! blastocyst development GO:0001824 49 26 0,000 0,08048609 0,09864979 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08048609 0,09859956 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08048609 0,09854939 ! neuron fate commitment GO:0048663 48 27 0,000 0,0834502 0,10212674 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0834502 0,10207482 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0834502 0,10202296 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0834502 0,10197114 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0834502 0,10191938 ! fat cell differentiation GO:0045444 50 27 0,000 0,0834502 0,10186767 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0834502 0,10181601 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0834502 0,10176441 ! autophagy GO:0006914 41 27 0,000 0,0834502 0,10171286 ! male gonad development GO:0008584 44 27 0,000 0,0834502 0,10166136 ! response to toxin GO:0009636 47 27 0,000 0,0834502 0,10160991 ! primary neural tube formation GO:0014020 51 27 0,000 0,0834502 0,10155851 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0834502 0,10150717 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0834502 0,10145588 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0834502 0,10140464 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0834502 0,10135345 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0834502 0,10130231 ! circadian rhythm GO:0007623 50 28 0,000 0,08640485 0,10483614 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08640485 0,1047833 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08640485 0,10473051 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08640485 0,10467777 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08640485 0,10462509 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08640485 0,10457246 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08640485 0,10451989 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08640485 0,10446737 ! synaptogenesis GO:0007416 42 28 0,000 0,08640485 0,1044149 ! lipid oxidation GO:0034440 43 28 0,000 0,08640485 0,10436248 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08640485 0,10431012 ! translational initiation GO:0006413 65 29 0,000 0,08935007 0,10781156 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08935007 0,10775752 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08935007 0,10770354 ! catechol metabolic process GO:0009712 54 29 0,000 0,08935007 0,1076496 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08935007 0,10759573 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08935007 0,1075419 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,08935007 0,10748813 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08935007 0,10743441 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08935007 0,10738075 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,08935007 0,10732714 ! cell fate determination GO:0001709 60 29 0,000 0,08935007 0,10727358 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08935007 0,10722008 ! detection of light stimulus GO:0009583 38 29 0,000 0,08935007 0,10716663 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08935007 0,10711323 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08935007 0,10705989 ! regulation of coagulation GO:0050818 46 29 0,000 0,08935007 0,1070066 ! phenol metabolic process GO:0018958 55 30 0,000 0,09228589 0,11046759 ! zinc ion transport GO:0006829 45 30 0,000 0,09228589 0,11041265 ! membrane docking GO:0022406 61 30 0,000 0,09228589 0,11035778 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09228589 0,11030296 ! cell junction assembly GO:0034329 78 30 0,000 0,09228589 0,11024819 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09228589 0,11019347 ! acute-phase response GO:0006953 49 30 0,000 0,09228589 0,11013881 ! myofibril assembly GO:0030239 47 30 0,000 0,09228589 0,11008421 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,09228589 0,11002966 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09228589 0,10997516 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,09228589 0,10992072 ! phospholipid transport GO:0015914 51 30 0,000 0,09228589 0,10986633 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09228589 0,10981199 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09228589 0,10975771 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09228589 0,10970348 ! eye morphogenesis GO:0048592 60 30 0,000 0,09228589 0,10964931 ! response to heat GO:0009408 50 30 0,000 0,09228589 0,10959519 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09521234 0,11301475 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09521234 0,11295902 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09521234 0,11290335 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09521234 0,11284773 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09521234 0,11279217 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09521234 0,11273666 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09521234 0,11268121 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09521234 0,11262581 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09521234 0,11257047 ! ovulation cycle process GO:0022602 49 31 0,000 0,09521234 0,11251518 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09521234 0,11245994 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09521234 0,11240476 ! peptide transport GO:0015833 55 31 0,000 0,09521234 0,11234963 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09521234 0,11229456 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09521234 0,11223954 ! mesoderm formation GO:0001707 69 31 0,000 0,09521234 0,11218457 ! natural killer cell activation GO:0030101 45 31 0,000 0,09521234 0,11212966 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09521234 0,1120748 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09521234 0,11202 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09521234 0,11196525 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09812946 0,11533927 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09812946 0,11528295 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09812946 0,11522669 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09812946 0,11517048 ! cholesterol transport GO:0030301 56 32 0,000 0,09812946 0,11511433 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09812946 0,11505823 ! spliceosome assembly GO:0000245 67 32 0,000 0,09812946 0,11500219 ! spindle organization GO:0007051 46 32 0,000 0,09812946 0,1149462 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09812946 0,11489026 ! metanephros development GO:0001656 74 32 0,000 0,09812946 0,11483438 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09812946 0,11477855 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09812946 0,11472278 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09812946 0,11466706 ! muscle cell development GO:0055001 49 32 0,000 0,09812946 0,1146114 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09812946 0,11455579 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09812946 0,11450024 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09812946 0,11444473 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09812946 0,11438929 ! ovulation cycle GO:0042698 51 32 0,000 0,09812946 0,11433389 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09812946 0,11427855 ! hindbrain development GO:0030902 61 32 0,000 0,09812946 0,11422326 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09812946 0,11416803 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09812946 0,11411285 ! gene silencing GO:0016458 65 32 0,000 0,09812946 0,11405772 ! post-embryonic development GO:0009791 69 33 0,000 0,10103727 0,11738082 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10103727 0,11732417 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10103727 0,11726757 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10103727 0,11721103 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10103727 0,11715454 ! cell fate specification GO:0001708 52 33 0,000 0,10103727 0,11709811 ! sterol transport GO:0015918 57 33 0,000 0,10103727 0,11704173 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10103727 0,11698541 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10103727 0,11692914 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10103727 0,11687292 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10103727 0,11681676 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,1039358 0,12011025 ! glial cell differentiation GO:0010001 63 34 0,000 0,1039358 0,12005259 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,1039358 0,11999498 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,1039358 0,11993743 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,1039358 0,11987993 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,1039358 0,11982249 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,1039358 0,11976511 ! mismatch repair GO:0006298 46 34 0,000 0,1039358 0,11970777 ! spermatid development GO:0007286 63 34 0,000 0,1039358 0,1196505 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,1039358 0,11959328 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,1039358 0,11953611 ! placenta development GO:0001890 53 34 0,000 0,1039358 0,119479 ! regulation of muscle development GO:0048634 70 35 0,000 0,10682508 0,12274171 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,10682508 0,12268313 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10682508 0,12262459 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10682508 0,12256612 ! odontogenesis GO:0042476 66 35 0,000 0,10682508 0,1225077 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10682508 0,12244933 ! female gonad development GO:0008585 58 35 0,000 0,10682508 0,12239102 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10682508 0,12233277 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,10682508 0,12227457 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10682508 0,12221643 ! neural tube formation GO:0001841 67 35 0,000 0,10682508 0,12215834 ! vesicle localization GO:0051648 64 35 0,000 0,10682508 0,12210031 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10970514 0,12533266 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10970514 0,12527317 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10970514 0,12521374 ! cell junction organization GO:0034330 86 36 0,000 0,10970514 0,12515437 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10970514 0,12509506 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10970514 0,1250358 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10970514 0,1249766 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10970514 0,12491745 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10970514 0,12485836 ! aerobic respiration GO:0009060 55 36 0,000 0,10970514 0,12479933 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,10970514 0,12474035 ! embryonic organ development GO:0048568 57 36 0,000 0,10970514 0,12468142 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10970514 0,12462256 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11257601 0,12782345 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11257601 0,12776315 ! meiosis I GO:0007127 65 37 0,000 0,11257601 0,12770292 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11257601 0,12764273 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11257601 0,12758261 ! organic anion transport GO:0015711 68 37 0,000 0,11257601 0,12752254 ! tissue remodeling GO:0048771 76 37 0,000 0,11257601 0,12746253 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11257601 0,12740258 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11257601 0,12734268 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11257601 0,12728284 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,11257601 0,12722305 ! pigment metabolic process GO:0042440 80 37 0,000 0,11257601 0,12716333 ! spermatid differentiation GO:0048515 66 37 0,000 0,11257601 0,12710365 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11543772 0,13027352 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11543772 0,13021245 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11543772 0,13015143 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11543772 0,13009047 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11543772 0,13002956 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,11543772 0,12996872 ! lipid homeostasis GO:0055088 67 38 0,000 0,11543772 0,12990793 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11543772 0,12984719 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11543772 0,12978652 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11543772 0,1297259 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11543772 0,12966534 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11543772 0,12960483 ! glucan metabolic process GO:0044042 62 38 0,000 0,11543772 0,12954438 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11829029 0,13268365 ! ear morphogenesis GO:0042471 60 39 0,000 0,11829029 0,13262183 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11829029 0,13256006 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11829029 0,13249834 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11829029 0,13243669 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11829029 0,13237509 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11829029 0,13231355 ! RNA modification GO:0009451 57 39 0,000 0,11829029 0,13225206 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11829029 0,13219064 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,12113376 0,1353054 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,12113376 0,13524261 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,12113376 0,13517988 ! feeding behavior GO:0007631 59 40 0,000 0,12113376 0,13511721 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,12113376 0,1350546 ! mesenchymal cell development GO:0014031 87 40 0,000 0,12113376 0,13499204 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,12113376 0,13492955 ! cytokinesis GO:0000910 72 40 0,000 0,12113376 0,13486711 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12396815 0,13795901 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12396815 0,13789523 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12396815 0,1378315 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12396815 0,13776784 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12396815 0,13770423 ! female gamete generation GO:0007292 61 41 0,000 0,12396815 0,13764069 ! polyol metabolic process GO:0019751 66 41 0,000 0,12396815 0,1375772 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12396815 0,13751377 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,1267935 0,14058302 ! regulation of tube size GO:0035150 71 42 0,000 0,1267935 0,14051827 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,1267935 0,14045357 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,1267935 0,14038893 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,1267935 0,14032436 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,1267935 0,14025984 ! neuron migration GO:0001764 79 42 0,000 0,1267935 0,14019538 ! regulation of protein secretion GO:0050708 71 42 0,000 0,1267935 0,14013098 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12960982 0,14317779 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12960982 0,14311209 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12960982 0,14304644 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12960982 0,14298085 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12960982 0,14291532 ! glucose transport GO:0015758 65 43 0,000 0,12960982 0,14284986 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12960982 0,14278445 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,12960982 0,1427191 ! neural tube development GO:0021915 77 43 0,000 0,12960982 0,14265381 ! striated muscle contraction GO:0006941 77 43 0,000 0,12960982 0,14258859 ! phagocytosis GO:0006909 90 43 0,000 0,12960982 0,14252342 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12960982 0,14245831 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13241716 0,14547748 ! hexose transport GO:0008645 67 44 0,000 0,13241716 0,14541109 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13241716 0,14534475 ! male sex differentiation GO:0046661 76 44 0,000 0,13241716 0,14527847 ! biopolymer methylation GO:0043414 84 44 0,000 0,13241716 0,14521226 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13241716 0,1451461 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,13241716 0,14508 ! developmental growth GO:0048589 82 44 0,000 0,13241716 0,14501397 ! glycolysis GO:0006096 65 45 0,000 0,13521554 0,14801118 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13521554 0,14794387 ! leukocyte migration GO:0050900 68 45 0,000 0,13521554 0,14787663 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13521554 0,14780944 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13521554 0,14774232 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13521554 0,14767525 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13521554 0,14760825 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13521554 0,14754131 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13521554 0,14747442 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13521554 0,1474076 ! cell growth GO:0016049 84 45 0,000 0,13521554 0,14734084 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13800498 0,15031235 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,13800498 0,15024433 ! pigmentation GO:0043473 100 46 0,000 0,13800498 0,15017638 ! positive regulation of defense response GO:0031349 76 47 0,000 0,14078551 0,15313289 ! response to calcium ion GO:0051592 81 47 0,000 0,14078551 0,15306369 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,14078551 0,15299456 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,14078551 0,15292548 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,14078551 0,15285647 ! methylation GO:0032259 90 47 0,000 0,14078551 0,15278753 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14355717 0,15572523 ! cellular component disassembly GO:0022411 86 48 0,000 0,14355717 0,15565505 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14355717 0,15558494 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14355717 0,15551489 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14355717 0,1554449 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,14355717 0,15537497 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14631998 0,15829401 ! regulation of ion transport GO:0043269 77 49 0,000 0,14631998 0,15822287 ! peptide metabolic process GO:0006518 76 49 0,000 0,14631998 0,15815179 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14631998 0,15808077 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14631998 0,15800982 ! endocrine system development GO:0035270 104 49 0,000 0,14631998 0,15793893 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,14631998 0,15786811 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,14631998 0,15779735 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14631998 0,15772665 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14631998 0,15765602 ! neuromuscular process GO:0050905 99 50 0,000 0,14907397 0,16055147 ! inner ear development GO:0048839 79 50 0,000 0,14907397 0,16047963 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14907397 0,16040786 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14907397 0,16033616 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,15181917 0,16321578 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15181917 0,16314289 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15181917 0,16307006 ! excretion GO:0007588 83 51 0,000 0,15181917 0,16299729 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,15181917 0,16292459 ! vesicle organization GO:0016050 107 51 0,000 0,15181917 0,16285195 ! regulation of cell shape GO:0008360 125 51 0,000 0,15181917 0,16277938 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15181917 0,16270687 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,1545556 0,1655658 ! membrane fusion GO:0006944 110 52 0,000 0,1545556 0,16549211 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,1545556 0,1654185 ! amino acid activation GO:0043038 92 52 0,000 0,1545556 0,16534494 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,1545556 0,16527146 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1572833 0,16811355 ! RNA catabolic process GO:0006401 93 53 0,000 0,1572833 0,1680389 ! regulation of translational initiation GO:0006446 82 53 0,000 0,1572833 0,16796432 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,1572833 0,1678898 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,1572833 0,16781535 ! cell maturation GO:0048469 100 53 0,000 0,1572833 0,16774096 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,16000228 0,17056512 ! cell recognition GO:0008037 85 54 0,000 0,16000228 0,17048959 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,16000228 0,17041411 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,16000228 0,17033871 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,16000228 0,17026337 ! glucose catabolic process GO:0006007 82 55 0,000 0,16271258 0,17307094 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,16271258 0,17299446 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16271258 0,17291805 ! gastrulation GO:0007369 112 55 0,000 0,16271258 0,17284171 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,16271258 0,17276543 ! nuclear export GO:0051168 97 55 0,000 0,16271258 0,17268922 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,16271258 0,17261308 ! sensory perception of smell GO:0007608 80 56 0,000 0,16541423 0,17540177 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16541423 0,17532451 ! proton transport GO:0015992 94 56 0,000 0,16541423 0,1752473 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,16541423 0,17517017 ! hydrogen transport GO:0006818 97 58 0,000 0,17079166 0,18078519 ! regulation of endocytosis GO:0030100 91 58 0,000 0,17079166 0,18070569 ! adult behavior GO:0030534 99 58 0,000 0,17079166 0,18062626 ! positive regulation of secretion GO:0051047 95 59 0,000 0,17346751 0,18337558 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,17346751 0,18329505 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17346751 0,18321458 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17346751 0,18313419 ! DNA catabolic process GO:0006308 86 59 0,000 0,17346751 0,18305387 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,17346751 0,18297362 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1761348 0,18570567 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1761348 0,18562433 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1761348 0,18554306 ! camera-type eye development GO:0043010 116 60 0,000 0,1761348 0,18546186 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,1761348 0,18538073 ! kidney development GO:0001822 122 60 0,000 0,1761348 0,18529967 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,17879358 0,18801458 ! mesoderm development GO:0007498 119 61 0,000 0,17879358 0,18793244 ! tRNA processing GO:0008033 89 61 0,000 0,17879358 0,18785038 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,17879358 0,18776838 ! ear development GO:0043583 103 62 0,000 0,18144387 0,19046857 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,18144387 0,1903855 ! gonad development GO:0008406 98 62 0,000 0,18144387 0,19030251 ! regulation of mitosis GO:0007088 105 63 0,000 0,18408569 0,19298918 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,18408569 0,19290513 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,18408569 0,19282115 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18671907 0,19549438 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18671907 0,19540935 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18671907 0,19532439 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18671907 0,1952395 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,18671907 0,19515469 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18934405 0,19781232 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18934405 0,19772646 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18934405 0,19764068 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,18934405 0,19755498 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19196063 0,20019821 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19196063 0,20011147 ! secondary metabolic process GO:0019748 116 66 0,000 0,19196063 0,20002481 ! developmental maturation GO:0021700 116 66 0,000 0,19196063 0,19993822 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,19456886 0,20256714 ! chromosome segregation GO:0007059 113 67 0,000 0,19456886 0,20247953 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,19456886 0,20239199 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,19456886 0,20230453 ! hexose catabolic process GO:0019320 104 67 0,000 0,19456886 0,20221714 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,19456886 0,20212982 ! adaptive immune response GO:0002250 119 67 0,000 0,19456886 0,20204259 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,19456886 0,20195542 ! amino acid transport GO:0006865 125 68 0,000 0,19716875 0,20456577 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19716875 0,20447759 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19716875 0,20438949 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,19716875 0,20430147 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19716875 0,20421352 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,19716875 0,20412565 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19976034 0,20671973 ! urogenital system development GO:0001655 137 69 0,000 0,19976034 0,20663086 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19976034 0,20654206 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19976034 0,20645334 ! appendage morphogenesis GO:0035107 135 70 0,000 0,20234365 0,20903341 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 0,000 0,2049187 0,21160275 ! appendage development GO:0048736 136 71 0,000 0,2049187 0,21151197 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,2049187 0,21142127 ! regulation of immune effector process GO:0002697 137 71 0,000 0,2049187 0,21133065 ! acute inflammatory response GO:0002526 113 72 0,000 0,20748553 0,21388611 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,20748553 0,21379451 ! carbohydrate transport GO:0008643 110 72 0,000 0,20748553 0,21370299 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,20748553 0,21361155 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,20748553 0,21352018 ! regulation of blood pressure GO:0008217 125 73 0,000 0,21004416 0,21606081 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,21004416 0,21596848 ! fertilization GO:0009566 90 73 0,000 0,21004416 0,21587622 ! neurotransmitter transport GO:0006836 123 74 0,000 0,21259461 0,21840419 ! meiosis GO:0007126 121 74 0,000 0,21259461 0,21831098 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,21259461 0,21821784 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,21259461 0,21812479 ! eye development GO:0001654 143 74 0,000 0,21259461 0,21803181 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,21513691 0,22054512 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21513691 0,22045119 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,21513691 0,22035734 ! meiotic cell cycle GO:0051321 122 75 0,000 0,21513691 0,22026357 ! rhythmic process GO:0048511 128 75 0,000 0,21513691 0,22016988 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21767108 0,22266863 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,21767108 0,222574 ! defense response to bacterium GO:0042742 89 76 0,000 0,21767108 0,22247945 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21767108 0,22238498 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,22019716 0,22487027 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,22019716 0,22477487 ! blood coagulation GO:0007596 146 78 0,000 0,22271516 0,22724881 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,22271516 0,22715247 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,22522512 0,2296151 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,22522512 0,22951785 ! response to metal ion GO:0010038 140 80 0,000 0,22772706 0,23196922 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22772706 0,23187106 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22772706 0,23177297 ! digestion GO:0007586 112 81 0,000 0,230221 0,23421215 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,230221 0,23411315 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,230221 0,23401425 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,23270697 0,23644129 ! response to nutrient GO:0007584 125 82 0,000 0,23270697 0,23634148 ! hemostasis GO:0007599 158 84 0,000 0,23765509 0,24126504 ! regulation of ligase activity GO:0051340 142 84 0,000 0,23765509 0,24116329 ! response to unfolded protein GO:0006986 131 85 0,000 0,2401173 0,24355912 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2401173 0,24345648 ! amine biosynthetic process GO:0009309 138 86 0,000 0,24257164 0,24584135 ! response to inorganic substance GO:0010035 153 86 0,000 0,24257164 0,24573783 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,24257164 0,24563441 ! tube morphogenesis GO:0035239 176 86 0,000 0,24257164 0,24553107 ! alcohol catabolic process GO:0046164 130 86 0,000 0,24257164 0,24542782 ! amine transport GO:0015837 155 86 0,000 0,24257164 0,24532466 ! cellular respiration GO:0045333 135 88 0,000 0,2474568 0,25016011 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,2474568 0,25005504 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2474568 0,24995006 ! cellular defense response GO:0006968 114 89 0,000 0,24988767 0,25229951 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,24988767 0,25219368 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,25231077 0,25453238 ! sex differentiation GO:0007548 145 90 0,000 0,25231077 0,2544257 ! sterol metabolic process GO:0016125 152 91 0,000 0,25472613 0,25675369 ! response to protein stimulus GO:0051789 149 91 0,000 0,25472613 0,25664617 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,25472613 0,25653874 ! regulation of defense response GO:0031347 149 92 0,000 0,25713376 0,25885516 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25713376 0,25874689 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25713376 0,25863872 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,25953369 0,26094361 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25953369 0,26083461 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,25953369 0,26072571 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,26192595 0,26301913 ! female pregnancy GO:0007565 164 94 0,000 0,26192595 0,2629094 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,26431056 0,26519233 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,26668755 0,26746571 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,26668755 0,26735427 ! positive regulation of immune response GO:0050778 156 96 0,000 0,26668755 0,26724292 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,26905694 0,26950499 ! hormone metabolic process GO:0042445 157 97 0,000 0,26905694 0,26939284 ! response to virus GO:0009615 160 98 0,000 0,27141874 0,27164455 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,27141874 0,2715316 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,273773 0,273773