pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6111-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regionalization GO:0003002 70 69 5,000 1,75E-06 3,225E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 3,000 2,89E-06 2,663E-03 ! positive regulation of growth GO:0045927 23 23 3,000 6,499E-06 3,993E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 7,33E-06 3,377E-03 GO:0033674|positive regulation of kinase activity, ! pattern specification process GO:0007389 96 94 5,000 1,075E-05 3,963E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 1,473E-05 4,526E-03 ! hindbrain development GO:0030902 11 11 2,000 2,488E-05 6,552E-03 ! proximal/distal pattern formation GO:0009954 11 11 2,000 2,488E-05 5,733E-03 ! negative regulation of translation GO:0017148 12 12 2,000 3,305E-05 6,768E-03 ! regulation of cell migration GO:0030334 71 71 4,000 3,91E-05 7,207E-03 ! negative regulation of signal transduction GO:0009968 71 71 4,000 3,91E-05 6,552E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 4,107E-05 6,307E-03 ! positive regulation of DNA replication GO:0045740 14 13 2,000 4,28E-05 6,068E-03 ! negative regulation of cell communication GO:0010648 76 76 4,000 5,439E-05 7,16E-03 ! limb development GO:0060173 39 39 3,000 5,667E-05 6,962E-03 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! positive regulation of cell motion GO:0051272 39 39 3,000 5,667E-05 6,527E-03 ! regulation of locomotion GO:0040012 79 79 4,000 6,555E-05 7,107E-03 ! regulation of cell motion GO:0051270 79 79 4,000 6,555E-05 6,712E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 6,758E-05 6,555E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 8,286E-05 7,635E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 9,849E-05 8,644E-03 ! pigmentation GO:0043473 17 17 2,000 1,002E-04 8,396E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 1,094E-04 8,763E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 1,198E-04 9,201E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 1,198E-04 8,833E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,403E-04 9,946E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 1,417E-04 9,675E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 1,519E-04 9,999E-03 ! anterior/posterior pattern formation GO:0009952 51 50 3,000 1,519E-04 9,654E-03 ! regulation of cell growth GO:0001558 97 96 4,000 1,661E-04 0,01020233 ! establishment or maintenance of cell polarity GO:0007163 21 20 2,000 1,661E-04 9,876E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 1,661E-04 9,567E-03 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 2,000 1,931E-04 0,01078238 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 1,931E-04 0,01046525 ! response to hormone stimulus GO:0009725 102 100 4,000 2,013E-04 0,01059982 ! positive regulation of transcription factor activity GO:0051091 22 22 2,000 2,227E-04 0,01140088 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 2,227E-04 0,01109275 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 2,897E-04 0,01405082 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 1,000 2,94E-04 0,01389247 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 2,94E-04 0,01354516 ! filopodium assembly GO:0046847 7 5 1,000 2,94E-04 0,01321479 GO:0030035|microspike assembly, ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 2,94E-04 0,01290015 ! hippocampus development GO:0021766 6 5 1,000 2,94E-04 0,01260015 ! thymic T cell selection GO:0045061 5 5 1,000 2,94E-04 0,01231378 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 2,94E-04 0,01204014 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 1,000 2,94E-04 0,0117784 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! tyrosine metabolic process GO:0006570 5 5 1,000 2,94E-04 0,0115278 ! corticosteroid receptor signaling pathway GO:0031958 5 5 1,000 2,94E-04 0,01128764 GO:0042921|glucocorticoid receptor signaling pathway, ! protein heterooligomerization GO:0051291 5 5 1,000 2,94E-04 0,01105728 ! positive regulation of phagocytosis GO:0050766 5 5 1,000 2,94E-04 0,01083613 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 1,000 2,94E-04 0,01062366 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 1,000 2,94E-04 0,01041936 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 1,000 2,94E-04 0,01022276 ! DNA methylation GO:0006306 5 5 1,000 2,94E-04 0,01003345 GO:0006305|DNA alkylation, ! peptidyl-lysine modification GO:0018205 5 5 1,000 2,94E-04 9,851E-03 ! pyrimidine base metabolic process GO:0006206 5 5 1,000 2,94E-04 9,675E-03 ! muscle adaptation GO:0043500 5 5 1,000 2,94E-04 9,505E-03 ! nucleus localization GO:0051647 5 5 1,000 2,94E-04 9,341E-03 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 3,000 3,092E-04 9,658E-03 ! positive regulation of DNA binding GO:0043388 26 25 2,000 3,288E-04 0,01010016 ! axonogenesis GO:0007409 66 62 3,000 3,509E-04 0,010602 ! positive regulation of binding GO:0051099 27 26 2,000 3,703E-04 0,01100722 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 3,703E-04 0,0108325 ! response to insulin stimulus GO:0032868 28 26 2,000 3,703E-04 0,01066325 ! positive regulation of protein metabolic process GO:0051247 64 64 3,000 3,965E-04 0,01124318 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 4,394E-04 0,01227086 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 4,394E-04 0,01208771 GO:0018409|peptide or protein amino-terminal blocking, ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 1,000 4,394E-04 0,01190995 GO:0016446|somatic hypermutation of immunoglobulin genes, ! virus-host interaction GO:0019048 6 6 1,000 4,394E-04 0,01173734 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 4,394E-04 0,01156967 ! retina development in camera-type eye GO:0060041 6 6 1,000 4,394E-04 0,01140671 ! cartilage condensation GO:0001502 7 6 1,000 4,394E-04 0,01124829 ! succinate metabolic process GO:0006105 7 6 1,000 4,394E-04 0,0110942 ! limbic system development GO:0021761 7 6 1,000 4,394E-04 0,01094428 ! positive regulation of cell growth GO:0030307 6 6 1,000 4,394E-04 0,01079836 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,394E-04 0,01065627 GO:0070667|negative regulation of mast cell proliferation, ! regulation of phagocytosis GO:0050764 6 6 1,000 4,394E-04 0,01051788 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,394E-04 0,01038303 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 1,000 4,394E-04 0,0102516 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 4,394E-04 0,01012346 ! multicellular organismal aging GO:0010259 6 6 1,000 4,394E-04 9,998E-03 ! nitric oxide mediated signal transduction GO:0007263 6 6 1,000 4,394E-04 9,877E-03 ! negative regulation of BMP signaling pathway GO:0030514 6 6 1,000 4,394E-04 9,758E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 4,394E-04 9,641E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 4,394E-04 9,528E-03 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 4,463E-04 9,563E-03 ! negative regulation of protein metabolic process GO:0051248 66 66 3,000 4,463E-04 9,453E-03 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 3,000 4,727E-04 9,9E-03 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of translation GO:0006417 69 69 3,000 5,29E-04 0,01095387 ! cell part morphogenesis GO:0032990 75 70 3,000 5,588E-04 0,01144336 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 2,000 5,695E-04 0,01153348 ! skeletal system morphogenesis GO:0048705 31 30 2,000 5,695E-04 0,01140812 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 6,131E-04 0,01214921 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 6,131E-04 0,01201996 ! keratinocyte proliferation GO:0043616 7 7 1,000 6,131E-04 0,01189343 ! regulation of mRNA processing GO:0050684 7 7 1,000 6,131E-04 0,01176954 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 6,131E-04 0,01164821 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 6,131E-04 0,01152935 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! cranial nerve development GO:0021545 7 7 1,000 6,131E-04 0,01141289 ! autonomic nervous system development GO:0048483 7 7 1,000 6,131E-04 0,01129876 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 6,131E-04 0,01118689 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 6,131E-04 0,01107722 ! negative regulation of T cell activation GO:0050868 7 7 1,000 6,131E-04 0,01096967 ! aging GO:0007568 32 31 2,000 6,281E-04 0,01113058 ! regulation of DNA replication GO:0006275 32 31 2,000 6,281E-04 0,01102457 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 6,904E-04 0,01200447 ! kidney development GO:0001822 32 32 2,000 6,904E-04 0,01189228 ! activation of protein kinase activity GO:0032147 35 33 2,000 7,566E-04 0,01291112 ! positive regulation of multicellular organismal process GO:0051240 76 76 3,000 7,636E-04 0,01291149 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 8,023E-04 0,01344198 ! embryonic forelimb morphogenesis GO:0035115 8 8 1,000 8,146E-04 0,01352481 ! T cell selection GO:0045058 8 8 1,000 8,146E-04 0,01340405 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 1,000 8,146E-04 0,01328543 ! phosphagen metabolic process GO:0006599 8 8 1,000 8,146E-04 0,01316889 GO:0006600|creatine metabolic process, ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 8,146E-04 0,01305438 ! sex determination GO:0007530 8 8 1,000 8,146E-04 0,01294184 ! immunoglobulin production during immune response GO:0002381 8 8 1,000 8,146E-04 0,01283123 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 8,146E-04 0,01272249 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 8,146E-04 0,01261558 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 8,146E-04 0,01251045 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 8,267E-04 0,01259116 ! regulation of protein modification process GO:0031399 79 78 3,000 8,423E-04 0,0127246 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 9,007E-04 0,01349617 ! neuron projection development GO:0031175 85 80 3,000 9,266E-04 0,01377195 ! MAPKKK cascade GO:0000165 82 81 3,000 9,709E-04 0,01431485 ! embryonic limb morphogenesis GO:0030326 36 36 2,000 9,789E-04 0,01431794 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 9,789E-04 0,0142052 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of cell size GO:0045793 9 9 1,000 1,044E-03 0,01502704 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,044E-03 0,01491055 ! cortical actin cytoskeleton organization GO:0030866 10 9 1,000 1,044E-03 0,01479586 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 1,000 1,044E-03 0,01468291 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 1,000 1,044E-03 0,01457168 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 1,000 1,044E-03 0,01446211 ! cerebral cortex development GO:0021987 9 9 1,000 1,044E-03 0,01435419 ! pigmentation during development GO:0048066 9 9 1,000 1,044E-03 0,01424786 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 1,000 1,044E-03 0,0141431 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 1,044E-03 0,01403986 ! negative regulation of caspase activity GO:0043154 9 9 1,000 1,044E-03 0,01393812 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,044E-03 0,01383785 GO:0060675|ureteric bud morphogenesis, ! regulation of dephosphorylation GO:0035303 9 9 1,000 1,044E-03 0,01373901 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,044E-03 0,01364157 ! histone acetylation GO:0016573 9 9 1,000 1,044E-03 0,0135455 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 1,044E-03 0,01345078 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 1,000 1,044E-03 0,01335737 ! regulation of transcription factor activity GO:0051090 38 37 2,000 1,061E-03 0,01348816 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 1,061E-03 0,01339578 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 1,061E-03 0,01330465 ! negative regulation of kinase activity GO:0033673 38 38 2,000 1,148E-03 0,01429295 ! urogenital system development GO:0001655 38 38 2,000 1,148E-03 0,01419703 ! axon guidance GO:0007411 39 38 2,000 1,148E-03 0,01410238 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 1,148E-03 0,01400899 ! positive regulation of protein modification process GO:0031401 39 39 2,000 1,239E-03 0,0150193 ! activation of MAPK activity GO:0000187 39 39 2,000 1,239E-03 0,01492114 ! heart development GO:0007507 90 87 3,000 1,269E-03 0,01518136 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,3E-03 0,01545778 ! cortical cytoskeleton organization GO:0030865 11 10 1,000 1,3E-03 0,01535869 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,3E-03 0,01526087 ! forelimb morphogenesis GO:0035136 10 10 1,000 1,3E-03 0,01516428 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,3E-03 0,01506891 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,3E-03 0,01497473 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 1,3E-03 0,01488172 ! plasma membrane organization GO:0007009 10 10 1,000 1,3E-03 0,01478985 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 1,3E-03 0,01469912 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! neuromuscular junction development GO:0007528 10 10 1,000 1,3E-03 0,01460949 ! protein export from nucleus GO:0006611 10 10 1,000 1,3E-03 0,01452095 ! positive regulation of biomineral formation GO:0070169 10 10 1,000 1,3E-03 0,01443347 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 1,000 1,3E-03 0,01434704 ! negative regulation of neuron differentiation GO:0045665 10 10 1,000 1,3E-03 0,01426164 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 1,3E-03 0,01417726 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 1,000 1,3E-03 0,01409386 ! nerve development GO:0021675 10 10 1,000 1,3E-03 0,01401144 ! protein stabilization GO:0050821 10 10 1,000 1,3E-03 0,01392998 ! negative regulation of transferase activity GO:0051348 40 40 2,000 1,334E-03 0,01421194 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 1,334E-03 0,01413026 ! brain development GO:0007420 91 90 3,000 1,439E-03 0,01515552 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 1,583E-03 0,01658068 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 1,583E-03 0,016487 ! skin development GO:0043588 11 11 1,000 1,583E-03 0,01639438 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,583E-03 0,01630279 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 1,583E-03 0,01621222 ! interaction with host GO:0051701 11 11 1,000 1,583E-03 0,01612265 ! oogenesis GO:0048477 11 11 1,000 1,583E-03 0,01603406 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,583E-03 0,01594645 GO:0006109|regulation of carbohydrate metabolic process, ! endocrine process GO:0050886 11 11 1,000 1,583E-03 0,01585978 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 1,583E-03 0,01577405 ! somatic diversification of immunoglobulins GO:0016445 11 11 1,000 1,583E-03 0,01568925 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,583E-03 0,01560535 ! regulation of DNA binding GO:0051101 47 45 2,000 1,88E-03 0,01842934 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 1,88E-03 0,01833183 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 1,893E-03 0,01836662 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 1,893E-03 0,01827045 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,893E-03 0,0181753 ! positive regulation of endocytosis GO:0045807 12 12 1,000 1,893E-03 0,01808112 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 1,000 1,893E-03 0,01798792 ! renal system process GO:0003014 12 12 1,000 1,893E-03 0,01789568 ! pallium development GO:0021543 13 12 1,000 1,893E-03 0,01780437 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 1,893E-03 0,01771399 ! somitogenesis GO:0001756 13 12 1,000 1,893E-03 0,01762453 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 1,000 1,893E-03 0,01753596 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 1,971E-03 0,0181649 ! regulation of catabolic process GO:0009894 48 47 2,000 2,132E-03 0,01954812 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 1,000 2,23E-03 0,02034553 GO:0016444|somatic cell DNA recombination, ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 2,23E-03 0,0202453 ! negative regulation of protein modification process GO:0031400 13 13 1,000 2,23E-03 0,02014606 ! regulation of DNA recombination GO:0000018 13 13 1,000 2,23E-03 0,02004779 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 2,23E-03 0,01995047 ! ureteric bud development GO:0001657 13 13 1,000 2,23E-03 0,01985409 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,23E-03 0,01975864 ! coenzyme catabolic process GO:0009109 13 13 1,000 2,23E-03 0,0196641 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! nucleobase metabolic process GO:0009112 13 13 1,000 2,23E-03 0,01957046 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 1,000 2,23E-03 0,01947771 ! immunoglobulin production GO:0002377 13 13 1,000 2,23E-03 0,01938583 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,23E-03 0,01929482 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,23E-03 0,01920466 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 1,000 2,23E-03 0,01911533 ! tissue homeostasis GO:0001894 13 13 1,000 2,23E-03 0,01902684 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 2,23E-03 0,01893916 ! leukocyte differentiation GO:0002521 50 49 2,000 2,404E-03 0,02032411 ! cell cycle arrest GO:0007050 49 49 2,000 2,404E-03 0,0202313 ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,404E-03 0,02013934 GO:0060538|skeletal muscle organ development, ! acetyl-CoA metabolic process GO:0006084 14 14 1,000 2,593E-03 0,02162033 ! protein amino acid acylation GO:0043543 14 14 1,000 2,593E-03 0,02152294 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 2,593E-03 0,02142643 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 2,593E-03 0,02133077 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of vasoconstriction GO:0019229 14 14 1,000 2,593E-03 0,02123597 ! DNA modification GO:0006304 14 14 1,000 2,593E-03 0,02114201 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 2,593E-03 0,02104887 ! positive regulation of osteoblast differentiation GO:0045669 14 14 1,000 2,593E-03 0,02095655 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 2,981E-03 0,02399137 ! positive regulation of ossification GO:0045778 15 15 1,000 2,981E-03 0,02388706 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 2,981E-03 0,02378365 ! ovarian follicle development GO:0001541 15 15 1,000 2,981E-03 0,02368114 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 1,000 2,981E-03 0,0235795 ! regulation of biomineral formation GO:0070167 15 15 1,000 2,981E-03 0,02347873 GO:0030500|regulation of bone mineralization, ! somatic diversification of immune receptors GO:0002200 15 15 1,000 2,981E-03 0,02337882 ! negative regulation of cell activation GO:0050866 15 15 1,000 2,981E-03 0,02327976 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 3,395E-03 0,02640113 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 3,395E-03 0,02629021 ! segmentation GO:0035282 17 16 1,000 3,395E-03 0,0261802 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 3,395E-03 0,02607112 ! cofactor catabolic process GO:0051187 16 16 1,000 3,395E-03 0,02596294 ! reproductive developmental process GO:0003006 56 56 2,000 3,522E-03 0,02682377 ! regulation of binding GO:0051098 60 57 2,000 3,704E-03 0,02809067 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 3,834E-03 0,02896195 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 1,000 3,834E-03 0,02884374 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 3,834E-03 0,02872649 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 3,834E-03 0,02861018 ! myelination GO:0042552 17 17 1,000 3,834E-03 0,02849482 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 3,834E-03 0,02838038 ! tissue remodeling GO:0048771 17 17 1,000 3,834E-03 0,02826686 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 3,834E-03 0,02815424 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 3,834E-03 0,02804252 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 3,834E-03 0,02793168 ! cellular aromatic compound metabolic process GO:0006725 60 59 2,000 4,084E-03 0,02963255 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,299E-03 0,03106844 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 4,299E-03 0,03094708 ! meiosis I GO:0007127 18 18 1,000 4,299E-03 0,03082666 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 4,299E-03 0,03070718 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 1,000 4,299E-03 0,03058862 ! ensheathment of neurons GO:0007272 18 18 1,000 4,299E-03 0,03047097 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 1,000 4,299E-03 0,03035422 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 4,299E-03 0,03023837 ! cellular respiration GO:0045333 62 61 2,000 4,487E-03 0,03144354 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 4,487E-03 0,03132444 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 2,000 4,487E-03 0,03120623 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 4,697E-03 0,03254608 GO:0060429|epithelium development, ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 4,788E-03 0,03304784 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 4,788E-03 0,03292453 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 4,788E-03 0,03280213 ! metanephros development GO:0001656 19 19 1,000 4,788E-03 0,03268064 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 4,788E-03 0,03256005 ! cellular response to oxidative stress GO:0034599 19 19 1,000 4,788E-03 0,03244034 ! peripheral nervous system development GO:0007422 19 19 1,000 4,788E-03 0,03232151 ! regulation of protein stability GO:0031647 19 19 1,000 4,788E-03 0,03220355 ! neural tube development GO:0021915 21 20 1,000 5,301E-03 0,03552791 ! female gamete generation GO:0007292 20 20 1,000 5,301E-03 0,03539919 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 5,364E-03 0,03568812 ! striated muscle tissue development GO:0014706 69 67 2,000 5,838E-03 0,03870493 ! Ras protein signal transduction GO:0007265 69 67 2,000 5,838E-03 0,0385662 ! mammary gland development GO:0030879 23 21 1,000 5,839E-03 0,03843272 ! negative regulation of protein transport GO:0051224 21 21 1,000 5,839E-03 0,03829594 ! regulation of action potential in neuron GO:0019228 21 21 1,000 5,839E-03 0,03816014 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 5,839E-03 0,0380253 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 5,839E-03 0,03789141 ! cellular amide metabolic process GO:0043603 22 22 1,000 6,401E-03 0,04139029 ! embryonic skeletal system development GO:0048706 22 22 1,000 6,401E-03 0,04124557 ! ovulation cycle process GO:0022602 22 22 1,000 6,401E-03 0,04110186 ! pigment biosynthetic process GO:0046148 22 22 1,000 6,401E-03 0,04095914 ! sterol biosynthetic process GO:0016126 22 22 1,000 6,401E-03 0,04081742 ! biopolymer methylation GO:0043414 22 22 1,000 6,401E-03 0,04067667 GO:0032259|methylation, ! neuron migration GO:0001764 22 22 1,000 6,401E-03 0,04053688 ! aerobic respiration GO:0009060 22 22 1,000 6,401E-03 0,04039806 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 1,000 6,401E-03 0,04026018 ! wound healing GO:0042060 74 70 2,000 6,596E-03 0,04134792 ! muscle tissue development GO:0060537 72 70 2,000 6,596E-03 0,04120776 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 1,000 6,986E-03 0,04349629 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 6,986E-03 0,04334984 ! female gonad development GO:0008585 23 23 1,000 6,986E-03 0,04320437 ! cell projection assembly GO:0030031 25 23 1,000 6,986E-03 0,04305988 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 7,132E-03 0,04381519 ! regulation of action potential GO:0001508 24 24 1,000 7,595E-03 0,04650061 ! glucose homeostasis GO:0042593 24 24 1,000 7,595E-03 0,04634663 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 7,595E-03 0,04619367 ! ovulation cycle GO:0042698 24 24 1,000 7,595E-03 0,04604172 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 7,595E-03 0,04589076 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 7,595E-03 0,04574079 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 8,226E-03 0,04938466 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 8,226E-03 0,04922432 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 8,226E-03 0,04906501 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 8,226E-03 0,04890674 ! heart morphogenesis GO:0003007 25 25 1,000 8,226E-03 0,04874948 ! regulation of endocytosis GO:0030100 25 25 1,000 8,226E-03 0,04859324 ! negative regulation of immune system process GO:0002683 25 25 1,000 8,226E-03 0,04843799 ! JAK-STAT cascade GO:0007259 26 25 1,000 8,226E-03 0,04828372 ! positive regulation of cytokine production GO:0001819 25 25 1,000 8,226E-03 0,04813044 ! positive regulation of defense response GO:0031349 26 26 1,000 8,881E-03 0,05179634 ! glycolysis GO:0006096 26 26 1,000 8,881E-03 0,05163294 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 8,881E-03 0,05147057 ! negative regulation of cell migration GO:0030336 26 26 1,000 8,881E-03 0,05130923 ! regulation of T cell differentiation GO:0045580 26 26 1,000 8,881E-03 0,05114888 ! regulation of blood vessel size GO:0050880 27 26 1,000 8,881E-03 0,05098954 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 1,000 8,881E-03 0,05083119 ! synapse organization GO:0050808 26 26 1,000 8,881E-03 0,05067382 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 8,894E-03 0,05058871 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 9,558E-03 0,05420267 ! tube development GO:0035295 83 81 2,000 9,862E-03 0,05575184 ! lymphocyte activation GO:0046649 82 81 2,000 9,862E-03 0,05558134 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,01025789 0,05763808 GO:0007254|JNK cascade, ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01025789 0,05746289 ! histone modification GO:0016570 28 28 1,000 0,01025789 0,05728876 ! developmental growth GO:0048589 28 28 1,000 0,01025789 0,05711568 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01025789 0,05694365 ! cartilage development GO:0051216 29 28 1,000 0,01025789 0,05677265 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01097962 0,06058517 ! viral reproductive process GO:0022415 29 29 1,000 0,01097962 0,06040432 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01097962 0,06022454 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 0,01097962 0,06004584 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01097962 0,05986819 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 1,000 0,01097962 0,05969158 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01097962 0,05951602 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01097962 0,05934149 ! response to UV GO:0009411 29 29 1,000 0,01097962 0,05916797 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,01172321 0,06299087 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 1,000 0,01172321 0,06280776 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01172321 0,0626257 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01172321 0,06244471 ! regulation of ossification GO:0030278 30 30 1,000 0,01172321 0,06226475 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01172321 0,06208583 ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 0,01172321 0,06190793 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 1,000 0,01172321 0,06173105 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01172321 0,06155518 ! regulation of translational initiation GO:0006446 31 31 1,000 0,01248839 0,06538663 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01248839 0,0652014 ! nucleoside metabolic process GO:0009116 31 31 1,000 0,01248839 0,06501722 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01248839 0,06483407 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01248839 0,06465195 ! B cell activation GO:0042113 31 31 1,000 0,01248839 0,06447085 ! camera-type eye development GO:0043010 31 31 1,000 0,01248839 0,06429077 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,01248839 0,06411169 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01248839 0,0639336 ! muscle fiber development GO:0048747 32 32 1,000 0,01327492 0,06777194 ! glucose catabolic process GO:0006007 32 32 1,000 0,01327492 0,06758472 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01327492 0,06739854 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,01327492 0,06721338 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,01327492 0,06702923 ! nuclear export GO:0051168 32 32 1,000 0,01327492 0,06684609 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01327492 0,06666395 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01327492 0,0664828 ! maintenance of location GO:0051235 33 32 1,000 0,01327492 0,06630263 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,01392465 0,0693598 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,01392465 0,06917285 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,01408255 0,06976919 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,01408255 0,06958214 ! tissue morphogenesis GO:0048729 94 93 2,000 0,01433464 0,07063832 ! epidermis development GO:0008544 94 94 2,000 0,01475147 0,07249857 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01491104 0,0730879 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01491104 0,07289404 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,01491104 0,0727012 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,01491104 0,07250937 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,01491104 0,07231856 ! secondary metabolic process GO:0019748 34 34 1,000 0,01491104 0,07212874 ! viral reproduction GO:0016032 34 34 1,000 0,01491104 0,07193993 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,01576015 0,07583802 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01576015 0,07564053 GO:0048609|reproductive process in a multicellular organism, ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,01576015 0,07544406 ! blood circulation GO:0008015 99 98 2,000 0,01648761 0,07872192 GO:0003013|circulatory system process, ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,01662964 0,0791949 ! gonad development GO:0008406 36 36 1,000 0,01662964 0,07899079 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01662964 0,07878773 ! coagulation GO:0050817 39 36 1,000 0,01662964 0,07858571 GO:0007596|blood coagulation, ! ectoderm development GO:0007398 99 99 2,000 0,0169389 0,07984245 ! muscle organ development GO:0007517 102 100 2,000 0,01739713 0,08179313 ! hemopoiesis GO:0030097 104 100 2,000 0,01739713 0,081585 ! meiosis GO:0007126 37 37 1,000 0,01751927 0,08194926 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 1,000 0,01751927 0,08174179 ! lung development GO:0030324 38 37 1,000 0,01751927 0,08153537 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 0,01751927 0,08132999 ! eye development GO:0001654 37 37 1,000 0,01751927 0,08112564 ! ATP synthesis coupled electron transport GO:0042773 37 37 1,000 0,01751927 0,08092232 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,01751927 0,08072002 ! adaptive immune response GO:0002250 37 37 1,000 0,01751927 0,08051872 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! hexose catabolic process GO:0019320 38 38 1,000 0,01842879 0,08448822 ! meiotic cell cycle GO:0051321 38 38 1,000 0,01842879 0,08427857 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,01842879 0,08406996 ! hemostasis GO:0007599 42 39 1,000 0,01935799 0,08809079 ! respiratory tube development GO:0030323 40 39 1,000 0,01935799 0,08787382 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,01935799 0,08765791 ! fatty acid biosynthetic process GO:0006633 39 39 1,000 0,01935799 0,08744306 ! respiratory system development GO:0060541 40 39 1,000 0,01935799 0,08722926 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01935799 0,08701651 ! protein oligomerization GO:0051259 39 39 1,000 0,01935799 0,08680479 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02030661 0,0908376 ! organelle localization GO:0051640 41 40 1,000 0,02030661 0,09061765 ! regulation of caspase activity GO:0043281 41 41 1,000 0,02127445 0,09470725 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,02127445 0,09447904 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,02127445 0,09425193 ! respiratory electron transport chain GO:0022904 43 42 1,000 0,02226125 0,09838725 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02226125 0,09815188 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,02226125 0,09791762 ! protein ubiquitination GO:0016567 43 42 1,000 0,02226125 0,09768449 ! forebrain development GO:0030900 43 42 1,000 0,02226125 0,09745246 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,02226125 0,09722153 ! reproductive structure development GO:0048608 43 43 1,000 0,0232668 0,10137285 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,0232668 0,10113376 ! mitochondrion organization GO:0007005 44 43 1,000 0,0232668 0,1008958 ! alcohol catabolic process GO:0046164 43 43 1,000 0,0232668 0,10065896 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,02533324 0,10934231 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,02639369 0,11365319 ! tube morphogenesis GO:0035239 47 46 1,000 0,02639369 0,11338827 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,02639369 0,11312457 ! regulation of membrane potential GO:0042391 46 46 1,000 0,02639369 0,1128621 ! rRNA transcription GO:0009303 5 5 0,000 0,02732075 0,11655589 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02732075 0,11628671 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02732075 0,11601877 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02732075 0,11575206 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02732075 0,11548657 ! reproductive cellular process GO:0048610 5 5 0,000 0,02732075 0,1152223 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02732075 0,11495923 ! prostate gland development GO:0030850 5 5 0,000 0,02732075 0,11469737 ! metencephalon development GO:0022037 5 5 0,000 0,02732075 0,11443669 ! water transport GO:0006833 5 5 0,000 0,02732075 0,1141772 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02732075 0,11391888 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02732075 0,11366173 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02732075 0,11340573 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02732075 0,11315089 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02732075 0,11289719 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02732075 0,11264462 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02732075 0,11239318 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02732075 0,11214286 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02732075 0,11189365 ! CTP metabolic process GO:0046036 5 5 0,000 0,02732075 0,11164555 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02732075 0,11139855 ! GTP metabolic process GO:0046039 5 5 0,000 0,02732075 0,11115264 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02732075 0,11090781 ! mRNA stabilization GO:0048255 5 5 0,000 0,02732075 0,11066405 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02732075 0,11042137 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02732075 0,11017975 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02732075 0,10993918 ! social behavior GO:0035176 5 5 0,000 0,02732075 0,10969966 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02732075 0,10946118 ! memory GO:0007613 5 5 0,000 0,02732075 0,10922374 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02732075 0,10898733 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02732075 0,10875193 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02732075 0,10851755 ! response to lipid GO:0033993 5 5 0,000 0,02732075 0,10828418 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02732075 0,10805181 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02732075 0,10782044 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02732075 0,10759005 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02732075 0,10736065 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02732075 0,10713222 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02732075 0,10690477 ! heart looping GO:0001947 5 5 0,000 0,02732075 0,10667827 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02732075 0,10645274 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02732075 0,10622815 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02732075 0,10600452 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02732075 0,10578182 ! pH reduction GO:0045851 5 5 0,000 0,02732075 0,10556005 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02732075 0,10533921 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02732075 0,1051193 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02732075 0,1049003 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02732075 0,10468221 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02732075 0,10446503 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02732075 0,10424875 ! adrenal gland development GO:0030325 5 5 0,000 0,02732075 0,10403336 ! melanocyte differentiation GO:0030318 5 5 0,000 0,02732075 0,10381885 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02732075 0,10360524 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02732075 0,10339249 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02732075 0,10318062 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02732075 0,10296962 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02732075 0,10275948 GO:0033135|regulation of peptidyl-serine phosphorylation, ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02732075 0,10255019 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02732075 0,10234176 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02732075 0,10213417 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02732075 0,10192742 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02732075 0,1017215 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02732075 0,10151642 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02732075 0,10131216 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02732075 0,10110872 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02732075 0,1009061 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02732075 0,10070429 ! response to ATP GO:0033198 5 5 0,000 0,02732075 0,10050328 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02732075 0,10030308 ! regulation of appetite GO:0032098 5 5 0,000 0,02732075 0,10010367 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02732075 0,09990505 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02732075 0,09970722 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,02732075 0,09951017 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02732075 0,09931389 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02732075 0,0991184 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02732075 0,09892366 ! receptor clustering GO:0043113 5 5 0,000 0,02732075 0,0987297 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02732075 0,09853649 ! fear response GO:0042596 5 5 0,000 0,02732075 0,09834403 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02732075 0,09815233 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02732075 0,09796137 ! retinol metabolic process GO:0042572 5 5 0,000 0,02732075 0,09777115 ! temperature homeostasis GO:0001659 5 5 0,000 0,02732075 0,09758168 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02732075 0,09739293 ! parturition GO:0007567 5 5 0,000 0,02732075 0,09720491 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02732075 0,09701762 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02732075 0,09683105 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02732075 0,09664519 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02732075 0,09646005 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02732075 0,09627561 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02732075 0,09609188 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02732075 0,09590885 ! response to UV-B GO:0010224 5 5 0,000 0,02732075 0,09572651 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02732075 0,09554487 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02732075 0,09536391 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02732075 0,09518364 ! interaction with symbiont GO:0051702 5 5 0,000 0,02732075 0,09500405 ! cellular extravasation GO:0045123 5 5 0,000 0,02732075 0,09482513 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02732075 0,09464689 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02732075 0,09446931 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02732075 0,09429241 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02732075 0,09411616 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02732075 0,09394057 ! response to amine stimulus GO:0014075 5 5 0,000 0,02732075 0,09376563 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02732075 0,09359135 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02732075 0,09341771 ! neuron recognition GO:0008038 5 5 0,000 0,02732075 0,09324471 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02732075 0,09307236 ! decidualization GO:0046697 5 5 0,000 0,02732075 0,09290064 ! hair follicle maturation GO:0048820 5 5 0,000 0,02732075 0,09272955 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02732075 0,09255909 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02732075 0,09238926 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02732075 0,09222005 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02732075 0,09205145 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02732075 0,09188348 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02732075 0,09171611 ! postreplication repair GO:0006301 5 5 0,000 0,02732075 0,09154935 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02732075 0,0913832 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02732075 0,09121765 ! histone methylation GO:0016571 5 5 0,000 0,02732075 0,0910527 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02732075 0,09088835 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02732075 0,09072458 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02732075 0,09056141 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02732075 0,09039882 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02732075 0,09023682 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02732075 0,09007539 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02732075 0,08991454 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02732075 0,08975427 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02732075 0,08959456 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02732075 0,08943543 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02732075 0,08927685 ! sterol catabolic process GO:0016127 5 5 0,000 0,02732075 0,08911884 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02732075 0,08896139 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02732075 0,08880449 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02732075 0,08864814 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02732075 0,08849235 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02732075 0,0883371 ! zymogen activation GO:0031638 5 5 0,000 0,02732075 0,08818239 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02732075 0,08802822 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02732075 0,0878746 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02732075 0,08772151 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02732075 0,08756895 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02732075 0,08741692 ! nucleosome positioning GO:0016584 5 5 0,000 0,02732075 0,08726542 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02732075 0,08711444 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02732075 0,08696398 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02732075 0,08681404 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02732075 0,08666462 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02732075 0,08651571 ! NADPH regeneration GO:0006740 5 5 0,000 0,02732075 0,08636732 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02732075 0,08621943 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02732075 0,08607204 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02732075 0,08592516 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02732075 0,08577878 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02732075 0,0856329 ! sarcomere organization GO:0045214 5 5 0,000 0,02732075 0,08548751 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02732075 0,08534262 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02732075 0,08519821 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02732075 0,0850543 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02732075 0,08491087 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02732075 0,08476792 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02732075 0,08462545 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02732075 0,08448346 ! spleen development GO:0048536 5 5 0,000 0,02732075 0,08434195 ! male genitalia development GO:0030539 5 5 0,000 0,02732075 0,08420091 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02732075 0,08406034 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02732075 0,08392024 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02732075 0,08378061 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02732075 0,08364144 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02732075 0,08350273 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02732075 0,08336448 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02732075 0,08322669 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02732075 0,08308935 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02732075 0,08295246 ! ATP catabolic process GO:0006200 5 5 0,000 0,02732075 0,08281603 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02732075 0,08268004 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02732075 0,0825445 ! blastocyst formation GO:0001825 5 5 0,000 0,02732075 0,0824094 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02732075 0,08227475 ! embryonic gut development GO:0048566 5 5 0,000 0,02732075 0,08214053 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02732075 0,08200675 ! activation of innate immune response GO:0002218 5 5 0,000 0,02732075 0,08187341 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02732075 0,08174049 ! catecholamine transport GO:0051937 5 5 0,000 0,02732075 0,08160801 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02732075 0,08147596 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02732075 0,08134434 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02732075 0,08121314 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02732075 0,08108236 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02732075 0,080952 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02732075 0,08082206 ! defense response to fungus GO:0050832 5 5 0,000 0,02732075 0,08069254 ! lysogeny GO:0030069 5 5 0,000 0,02732075 0,08056343 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02732075 0,08043474 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02732075 0,08030645 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02732075 0,08017857 ! response to nicotine GO:0035094 5 5 0,000 0,02732075 0,0800511 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02732075 0,07992404 ! mitochondrion localization GO:0051646 5 5 0,000 0,02732075 0,07979738 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02732075 0,07967111 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,02747199 0,07998558 ! regulation of blood pressure GO:0008217 48 47 1,000 0,02747199 0,07985942 ! sex differentiation GO:0007548 47 47 1,000 0,02747199 0,07973366 ! rhythmic process GO:0048511 47 47 1,000 0,02747199 0,07960829 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,02856792 0,08265413 ! DNA recombination GO:0006310 48 48 1,000 0,02856792 0,08252458 ! gland development GO:0048732 51 49 1,000 0,02968128 0,08560657 ! regulation of defense response GO:0031347 50 50 1,000 0,03081184 0,08872848 ! negative regulation of transport GO:0051051 51 50 1,000 0,03081184 0,08859005 ! T cell activation GO:0042110 51 50 1,000 0,03081184 0,08845206 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,03081184 0,0883145 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03081184 0,08817737 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,0319594 0,09131964 ! protein maturation GO:0051604 51 51 1,000 0,0319594 0,09117828 ! axon extension GO:0048675 7 6 0,000 0,03269701 0,09313848 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03269701 0,09299475 ! tRNA modification GO:0006400 6 6 0,000 0,03269701 0,09285146 ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03269701 0,09270861 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03269701 0,0925662 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03269701 0,09242423 ! regulation of S phase GO:0033261 6 6 0,000 0,03269701 0,09228269 ! myotube differentiation GO:0014902 6 6 0,000 0,03269701 0,09214159 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03269701 0,09200091 ! bone remodeling GO:0046849 6 6 0,000 0,03269701 0,09186067 ! N-glycan processing GO:0006491 6 6 0,000 0,03269701 0,09172085 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03269701 0,09158146 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03269701 0,09144249 ! RNA methylation GO:0001510 6 6 0,000 0,03269701 0,09130394 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03269701 0,09116581 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03269701 0,09102809 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 0,000 0,03269701 0,0908908 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03269701 0,09075391 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03269701 0,09061744 ! androgen metabolic process GO:0008209 6 6 0,000 0,03269701 0,09048138 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03269701 0,09034572 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03269701 0,09021048 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03269701 0,09007563 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03269701 0,08994119 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03269701 0,08980715 ! pathogenesis GO:0009405 6 6 0,000 0,03269701 0,08967351 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03269701 0,08954026 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03269701 0,08940742 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03269701 0,08927496 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03269701 0,0891429 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03269701 0,08901122 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03269701 0,08887994 ! arginine metabolic process GO:0006525 6 6 0,000 0,03269701 0,08874904 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03269701 0,08861853 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03269701 0,0884884 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03269701 0,08835865 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03269701 0,08822928 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03269701 0,08810029 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03269701 0,08797168 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03269701 0,08784344 ! ER overload response GO:0006983 6 6 0,000 0,03269701 0,08771557 ! V(D)J recombination GO:0033151 6 6 0,000 0,03269701 0,08758808 ! focal adhesion formation GO:0048041 7 6 0,000 0,03269701 0,08746096 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03269701 0,0873342 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03269701 0,08720781 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03269701 0,08708179 ! regulation of heart rate GO:0002027 6 6 0,000 0,03269701 0,08695613 ! lipid digestion GO:0044241 6 6 0,000 0,03269701 0,08683083 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03269701 0,0867059 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03269701 0,08658132 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03269701 0,0864571 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03269701 0,08633324 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03269701 0,08620973 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03269701 0,08608657 ! ruffle organization GO:0031529 6 6 0,000 0,03269701 0,08596376 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,03269701 0,08584131 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03269701 0,0857192 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03269701 0,08559744 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03269701 0,08547603 ! L-amino acid transport GO:0015807 6 6 0,000 0,03269701 0,08535496 ! bone mineralization GO:0030282 6 6 0,000 0,03269701 0,08523423 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03269701 0,08511384 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03269701 0,08499379 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03269701 0,08487408 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,03269701 0,08475471 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03269701 0,08463567 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03269701 0,08451697 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03269701 0,0843986 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03269701 0,08428056 ! regulation of organ growth GO:0046620 6 6 0,000 0,03269701 0,08416285 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03269701 0,08404546 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03269701 0,08392841 ! response to dsRNA GO:0043331 6 6 0,000 0,03269701 0,08381168 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03269701 0,08369528 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03269701 0,08357919 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03269701 0,08346343 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03269701 0,08334799 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03269701 0,08323287 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03269701 0,08311807 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03269701 0,08300358 ! erythrocyte development GO:0048821 6 6 0,000 0,03269701 0,08288941 ! renal water homeostasis GO:0003091 6 6 0,000 0,03269701 0,08277555 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03269701 0,082662 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03269701 0,08254876 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03269701 0,08243584 ! ribosome assembly GO:0042255 6 6 0,000 0,03269701 0,08232322 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03269701 0,08221091 ! diencephalon development GO:0021536 6 6 0,000 0,03269701 0,08209891 ! fucose catabolic process GO:0019317 6 6 0,000 0,03269701 0,08198721 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03269701 0,08187581 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03269701 0,08176472 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03269701 0,08165393 ! regulation of cell division GO:0051302 6 6 0,000 0,03269701 0,08154343 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03269701 0,08143324 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03269701 0,08132334 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03269701 0,08121374 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03269701 0,08110444 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03269701 0,08099543 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03269701 0,08088671 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03269701 0,08077828 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03269701 0,08067014 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03269701 0,0805623 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03269701 0,08045474 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03269701 0,08034746 ! thymus development GO:0048538 6 6 0,000 0,03269701 0,08024048 ! lymph node development GO:0048535 6 6 0,000 0,03269701 0,08013377 ! organic cation transport GO:0015695 6 6 0,000 0,03269701 0,08002735 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03269701 0,07992122 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03269701 0,07981536 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03269701 0,07970979 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03269701 0,07960449 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03269701 0,07949947 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03269701 0,07939473 ! alditol metabolic process GO:0019400 6 6 0,000 0,03269701 0,07929026 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03269701 0,07918607 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03269701 0,07908215 ! maternal placenta development GO:0001893 6 6 0,000 0,03269701 0,0789785 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03269701 0,07887513 ! localization within membrane GO:0051668 6 6 0,000 0,03269701 0,07877202 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,03312373 0,07969587 ! response to light stimulus GO:0009416 53 52 1,000 0,03312373 0,07959196 ! response to hypoxia GO:0001666 53 53 1,000 0,03430464 0,08232219 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,03430464 0,08221514 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03430464 0,08210837 ! regulation of protein transport GO:0051223 53 53 1,000 0,03430464 0,08200187 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 0,0355019 0,0847539 ! sulfur metabolic process GO:0006790 55 54 1,000 0,0355019 0,08464425 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,03671533 0,08742422 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,03671533 0,08731142 ! extracellular structure organization GO:0043062 56 56 1,000 0,0379447 0,09011867 ! regulation of nervous system development GO:0051960 57 56 1,000 0,0379447 0,09000269 ! respiratory burst GO:0045730 7 7 0,000 0,03804434 0,09012303 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03804434 0,09000734 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03804434 0,08989195 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03804434 0,08977685 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03804434 0,08966204 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03804434 0,08954753 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03804434 0,08943331 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03804434 0,08931939 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03804434 0,08920575 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03804434 0,0890924 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03804434 0,08897934 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03804434 0,08886656 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03804434 0,08875407 ! axis specification GO:0009798 7 7 0,000 0,03804434 0,08864187 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03804434 0,08852995 ! visual behavior GO:0007632 7 7 0,000 0,03804434 0,08841831 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03804434 0,08830695 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,03804434 0,08819587 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03804434 0,08808507 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,03804434 0,08797455 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03804434 0,08786431 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,03804434 0,08775434 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03804434 0,08764465 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03804434 0,08753523 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03804434 0,08742608 ! digestive system development GO:0055123 7 7 0,000 0,03804434 0,08731721 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,03804434 0,08720861 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03804434 0,08710027 ! protein targeting to ER GO:0045047 8 7 0,000 0,03804434 0,08699221 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03804434 0,08688441 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03804434 0,08677688 ! endoderm development GO:0007492 7 7 0,000 0,03804434 0,08666962 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03804434 0,08656262 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03804434 0,08645588 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,03804434 0,08634941 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,03804434 0,0862432 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03804434 0,08613725 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03804434 0,08603156 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,03804434 0,08592613 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03804434 0,08582095 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03804434 0,08571604 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03804434 0,08561138 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03804434 0,08550697 ! response to X-ray GO:0010165 7 7 0,000 0,03804434 0,08540282 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,03804434 0,08529893 ! UV protection GO:0009650 7 7 0,000 0,03804434 0,08519528 ! DNA integration GO:0015074 7 7 0,000 0,03804434 0,08509189 ! myofibril assembly GO:0030239 7 7 0,000 0,03804434 0,08498875 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03804434 0,08488586 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03804434 0,08478321 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03804434 0,08468082 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03804434 0,08457867 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03804434 0,08447677 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03804434 0,08437511 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03804434 0,0842737 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03804434 0,08417253 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,03804434 0,08407161 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03804434 0,08397092 ! axon cargo transport GO:0008088 7 7 0,000 0,03804434 0,08387048 ! eating behavior GO:0042755 7 7 0,000 0,03804434 0,08377027 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03804434 0,08367031 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03804434 0,08357058 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03804434 0,08347109 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03804434 0,08337184 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03804434 0,08327282 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03804434 0,08317404 ! induction of an organ GO:0001759 7 7 0,000 0,03804434 0,0830755 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03804434 0,08297718 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03804434 0,0828791 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03804434 0,08278125 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03804434 0,08268363 ! platelet activation GO:0030168 8 7 0,000 0,03804434 0,08258624 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03804434 0,08248908 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03804434 0,08239215 ! natural killer cell activation GO:0030101 7 7 0,000 0,03804434 0,08229544 ! response to gamma radiation GO:0010332 8 7 0,000 0,03804434 0,08219897 ! NADP metabolic process GO:0006739 7 7 0,000 0,03804434 0,08210272 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03804434 0,08200669 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03804434 0,08191089 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03804434 0,08181531 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,03804434 0,08171995 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03804434 0,08162482 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03804434 0,08152991 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03804434 0,08143521 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03804434 0,08134074 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03804434 0,08124649 ! cell-cell recognition GO:0009988 8 7 0,000 0,03804434 0,08115245 ! hormone catabolic process GO:0042447 7 7 0,000 0,03804434 0,08105863 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03804434 0,08096503 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03804434 0,08087165 ! oxygen transport GO:0015671 7 7 0,000 0,03804434 0,08077848 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03804434 0,08068552 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03804434 0,08059278 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03804434 0,08050025 ! regulation of axon extension GO:0030516 7 7 0,000 0,03804434 0,08040793 ! cell killing GO:0001906 7 7 0,000 0,03804434 0,08031583 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03804434 0,08022393 ! adult feeding behavior GO:0008343 7 7 0,000 0,03804434 0,08013225 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03804434 0,08004077 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03804434 0,07994951 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03804434 0,07985845 ! response to cold GO:0009409 7 7 0,000 0,03804434 0,0797676 ! regulation of protein localization GO:0032880 58 57 1,000 0,03918983 0,08207597 ! regulation of cell development GO:0060284 60 59 1,000 0,04172652 0,08728942 ! sterol metabolic process GO:0016125 59 59 1,000 0,04172652 0,08719045 ! immune effector process GO:0002252 59 59 1,000 0,04172652 0,08709171 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04336288 0,09040473 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04336288 0,09030258 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04336288 0,09020066 ! positive regulation of translation GO:0045727 8 8 0,000 0,04336288 0,09009897 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04336288 0,08999751 ! superoxide anion generation GO:0042554 8 8 0,000 0,04336288 0,08989627 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04336288 0,08979526 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04336288 0,08969448 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04336288 0,08959393 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04336288 0,0894936 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04336288 0,0893935 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04336288 0,08929361 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,04336288 0,08919396 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04336288 0,08909452 ! zinc ion transport GO:0006829 8 8 0,000 0,04336288 0,08899531 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04336288 0,08889631 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04336288 0,08879754 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04336288 0,08869898 ! lipid localization GO:0010876 8 8 0,000 0,04336288 0,08860065 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04336288 0,08850253 ! response to cAMP GO:0051591 8 8 0,000 0,04336288 0,08840463 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04336288 0,08830694 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04336288 0,08820948 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04336288 0,08811222 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04336288 0,08801518 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04336288 0,08791836 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04336288 0,08782174 ! sensory perception of taste GO:0050909 8 8 0,000 0,04336288 0,08772534 ! organelle fusion GO:0048284 8 8 0,000 0,04336288 0,08762915 ! pancreas development GO:0031016 8 8 0,000 0,04336288 0,08753317 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04336288 0,0874374 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04336288 0,08734184 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04336288 0,08724649 ! sperm motility GO:0030317 8 8 0,000 0,04336288 0,08715135 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04336288 0,08705641 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04336288 0,08696168 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04336288 0,08686716 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04336288 0,08677284 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04336288 0,08667873 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04336288 0,08658482 ! Golgi organization GO:0007030 8 8 0,000 0,04336288 0,08649111 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04336288 0,08639761 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04336288 0,0863043 ! fructose metabolic process GO:0006000 8 8 0,000 0,04336288 0,0862112 ! mannose metabolic process GO:0006013 9 8 0,000 0,04336288 0,0861183 ! NAD metabolic process GO:0019674 8 8 0,000 0,04336288 0,0860256 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04336288 0,0859331 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04336288 0,0858408 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,04336288 0,0857487 ! response to fungus GO:0009620 8 8 0,000 0,04336288 0,08565679 ! stem cell differentiation GO:0048863 8 8 0,000 0,04336288 0,08556508 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04336288 0,08547357 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04336288 0,08538225 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04336288 0,08529113 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04336288 0,0852002 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04336288 0,08510946 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04336288 0,08501892 ! vasoconstriction GO:0042310 8 8 0,000 0,04336288 0,08492857 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04336288 0,08483841 ! muscle cell development GO:0055001 8 8 0,000 0,04336288 0,08474845 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04336288 0,08465867 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04336288 0,08456908 ! sensory perception of pain GO:0019233 8 8 0,000 0,04336288 0,08447969 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04336288 0,08439048 ! mRNA cleavage GO:0006379 8 8 0,000 0,04336288 0,08430146 ! chromatin silencing GO:0006342 8 8 0,000 0,04336288 0,08421263 ! tissue regeneration GO:0042246 8 8 0,000 0,04336288 0,08412398 ! salivary gland development GO:0007431 8 8 0,000 0,04336288 0,08403553 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04336288 0,08394725 ! T cell homeostasis GO:0043029 8 8 0,000 0,04336288 0,08385917 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04336288 0,08377126 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,04336288 0,08368354 ! water homeostasis GO:0030104 8 8 0,000 0,04336288 0,08359601 ! cofactor transport GO:0051181 8 8 0,000 0,04336288 0,08350866 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04336288 0,08342149 ! acid secretion GO:0046717 8 8 0,000 0,04336288 0,0833345 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,04336288 0,08324769 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04336288 0,08316107 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04336288 0,08307462 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04336288 0,08298835 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04336288 0,08290227 ! regulation of RNA stability GO:0043487 8 8 0,000 0,04336288 0,08281636 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04336288 0,08273063 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04336288 0,08264507 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04336288 0,0825597 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04336288 0,08247449 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04336288 0,08238947 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04336288 0,08230462 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04336288 0,08221994 ! developmental induction GO:0031128 8 8 0,000 0,04336288 0,08213544 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04336288 0,08205111 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04336288 0,08196696 ! actin filament polymerization GO:0030041 9 8 0,000 0,04336288 0,08188298 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04336288 0,08179917 ! peptide hormone processing GO:0016486 8 8 0,000 0,04336288 0,08171553 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04336288 0,08163206 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04336288 0,08154876 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,0456447 0,08575247 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,0456447 0,08566515 ! regulation of secretion GO:0051046 65 63 1,000 0,04698014 0,08808179 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,04698014 0,08799228 ! glucose metabolic process GO:0006006 63 63 1,000 0,04698014 0,08790295 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,04832996 0,09033684 ! lactation GO:0007595 10 9 0,000 0,04865278 0,0908481 ! embryonic pattern specification GO:0009880 10 9 0,000 0,04865278 0,09075615 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,04865278 0,09066438 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,04865278 0,0905728 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,04865278 0,09048141 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,04865278 0,0903902 ! viral genome replication GO:0019079 9 9 0,000 0,04865278 0,09029917 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,04865278 0,09020833 ! copper ion transport GO:0006825 9 9 0,000 0,04865278 0,09011766 ! lipid phosphorylation GO:0046834 9 9 0,000 0,04865278 0,09002718 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,04865278 0,08993689 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,04865278 0,08984677 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,04865278 0,08975683 ! RNA polyadenylation GO:0043631 9 9 0,000 0,04865278 0,08966708 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,04865278 0,0895775 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,04865278 0,0894881 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,04865278 0,08939888 ! phospholipid efflux GO:0033700 9 9 0,000 0,04865278 0,08930984 ! response to alkaloid GO:0043279 10 9 0,000 0,04865278 0,08922097 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,04865278 0,08913228 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,04865278 0,08904377 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,04865278 0,08895543 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,04865278 0,08886727 ! response to ethanol GO:0045471 9 9 0,000 0,04865278 0,08877928 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,04865278 0,08869147 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,04865278 0,08860383 ! methionine metabolic process GO:0006555 9 9 0,000 0,04865278 0,08851636 ! glutamine metabolic process GO:0006541 9 9 0,000 0,04865278 0,08842907 ! response to osmotic stress GO:0006970 9 9 0,000 0,04865278 0,08834195 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,04865278 0,088255 ! central nervous system neuron development GO:0021954 10 9 0,000 0,04865278 0,08816822 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,04865278 0,08808161 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,04865278 0,08799517 ! L-glutamate transport GO:0015813 9 9 0,000 0,04865278 0,0879089 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,04865278 0,0878228 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,04865278 0,08773686 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,04865278 0,0876511 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,04865278 0,0875655 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,04865278 0,08748007 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,04865278 0,08739481 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,04865278 0,08730971 ! DNA replication initiation GO:0006270 9 9 0,000 0,04865278 0,08722478 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,04865278 0,08714002 GO:0006692|prostanoid metabolic process, ! regulation of cellular pH GO:0030641 9 9 0,000 0,04865278 0,08705541 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,04865278 0,08697098 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,04865278 0,0868867 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,04865278 0,08680259 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,04865278 0,08671864 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,04865278 0,08663486 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,04865278 0,08655123 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,04865278 0,08646777 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,04865278 0,08638447 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,04865278 0,08630132 ! collagen catabolic process GO:0030574 9 9 0,000 0,04865278 0,08621834 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,04865278 0,08613552 ! purine base metabolic process GO:0006144 9 9 0,000 0,04865278 0,08605286 ! gas transport GO:0015669 9 9 0,000 0,04865278 0,08597035 ! cholesterol efflux GO:0033344 9 9 0,000 0,04865278 0,085888 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,04865278 0,08580581 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,04865278 0,08572378 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,04865278 0,08564191 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,04865278 0,08556019 ! defense response to virus GO:0051607 9 9 0,000 0,04865278 0,08547862 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,04865278 0,08539721 ! actin filament-based movement GO:0030048 9 9 0,000 0,04865278 0,08531596 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,04865278 0,08523486 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,05246377 0,09182405 ! response to radiation GO:0009314 70 68 1,000 0,0538692 0,09419443 ! regulation of cell size GO:0008361 68 68 1,000 0,0538692 0,09410515 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0539142 0,09409457 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0539142 0,09400555 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0539142 0,0939167 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0539142 0,09382801 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0539142 0,0937395 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,0539142 0,09365115 ! neuron maturation GO:0042551 10 10 0,000 0,0539142 0,09356296 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0539142 0,09347495 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,0539142 0,09338709 GO:0045767|regulation of anti-apoptosis, ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0539142 0,09329941 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0539142 0,09321188 ! hormone secretion GO:0046879 10 10 0,000 0,0539142 0,09312452 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0539142 0,09303733 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0539142 0,0929503 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,0539142 0,09286343 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0539142 0,09277672 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0539142 0,09269017 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0539142 0,09260379 ! glial cell development GO:0021782 10 10 0,000 0,0539142 0,09251757 ! phototransduction GO:0007602 11 10 0,000 0,0539142 0,0924315 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0539142 0,0923456 ! fat cell differentiation GO:0045444 10 10 0,000 0,0539142 0,09225986 ! myoblast differentiation GO:0045445 10 10 0,000 0,0539142 0,09217427 ! centrosome cycle GO:0007098 10 10 0,000 0,0539142 0,09208885 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0539142 0,09200358 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0539142 0,09191847 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0539142 0,09183352 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0539142 0,09174872 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,0539142 0,09166408 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0539142 0,0915796 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0539142 0,09149527 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,0539142 0,0914111 ! lysosomal transport GO:0007041 10 10 0,000 0,0539142 0,09132708 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0539142 0,09124322 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0539142 0,09115951 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0539142 0,09107595 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0539142 0,09099255 ! exocrine system development GO:0035272 10 10 0,000 0,0539142 0,0909093 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0539142 0,0908262 ! embryo implantation GO:0007566 11 10 0,000 0,0539142 0,09074326 ! regulation of protein binding GO:0043393 11 10 0,000 0,0539142 0,09066046 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0539142 0,09057782 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0539142 0,09049532 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,0539142 0,09041298 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0539142 0,09033079 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0539142 0,09024874 ! cytolysis GO:0019835 10 10 0,000 0,0539142 0,09016685 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0539142 0,0900851 ! histone deacetylation GO:0016575 10 10 0,000 0,0539142 0,0900035 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0539142 0,08992205 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0539142 0,08984075 ! gland morphogenesis GO:0022612 10 10 0,000 0,0539142 0,08975959 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0539142 0,08967858 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0539142 0,08959772 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0539142 0,089517 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0539142 0,08943642 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,0539142 0,089356 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0539142 0,08927571 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0539142 0,08919557 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0539142 0,08911558 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,0539142 0,08903572 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,0539142 0,08895601 ! gut development GO:0048565 10 10 0,000 0,0539142 0,08887645 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,0539142 0,08879702 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,0539142 0,08871774 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,0539142 0,0886386 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0539142 0,0885596 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0539142 0,08848074 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,0539142 0,08840202 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,05528806 0,09057413 ! positive regulation of transport GO:0051050 71 70 1,000 0,05672018 0,09283774 ! growth GO:0040007 70 70 1,000 0,05672018 0,09275537 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,05672018 0,09267314 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 1,000 0,05816538 0,09495022 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,05816538 0,09486619 GO:0006874|cellular calcium ion homeostasis, ! regulation of cell activation GO:0050865 71 71 1,000 0,05816538 0,09478231 ! protein secretion GO:0009306 11 11 0,000 0,05914728 0,0962972 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,05914728 0,09621221 ! negative regulation of defense response GO:0031348 11 11 0,000 0,05914728 0,09612737 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,05914728 0,09604267 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,05914728 0,09595813 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,05914728 0,09587373 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,05914728 0,09578948 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,05914728 0,09570538 ! signal complex assembly GO:0007172 11 11 0,000 0,05914728 0,09562143 ! microtubule-based transport GO:0010970 11 11 0,000 0,05914728 0,09553763 ! endothelial cell migration GO:0043542 11 11 0,000 0,05914728 0,09545397 ! peroxisomal transport GO:0043574 11 11 0,000 0,05914728 0,09537046 ! protein amino acid methylation GO:0006479 11 11 0,000 0,05914728 0,09528709 GO:0008213|protein amino acid alkylation, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,05914728 0,09520387 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,05914728 0,0951208 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,05914728 0,09503787 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,05914728 0,09495508 ! T cell proliferation GO:0042098 11 11 0,000 0,05914728 0,09487244 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,05914728 0,09478994 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,05914728 0,09470759 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,05914728 0,09462538 ! spinal cord development GO:0021510 11 11 0,000 0,05914728 0,09454331 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,05914728 0,09446138 ! smooth muscle contraction GO:0006939 11 11 0,000 0,05914728 0,0943796 ! cellular response to starvation GO:0009267 11 11 0,000 0,05914728 0,09429795 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,05914728 0,09421645 ! digestive system process GO:0022600 11 11 0,000 0,05914728 0,09413509 ! mitotic spindle organization GO:0007052 11 11 0,000 0,05914728 0,09405387 ! fucose metabolic process GO:0006004 11 11 0,000 0,05914728 0,09397279 ! membrane budding GO:0006900 11 11 0,000 0,05914728 0,09389185 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,05914728 0,09381104 ! monoamine transport GO:0015844 11 11 0,000 0,05914728 0,09373038 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,05914728 0,09364986 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,05914728 0,09356947 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,05914728 0,09348922 ! body fluid secretion GO:0007589 11 11 0,000 0,05914728 0,09340911 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,05914728 0,09332914 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,05914728 0,0932493 ! intermediate filament-based process GO:0045103 11 11 0,000 0,05914728 0,0931696 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,05914728 0,09309004 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,05914728 0,09301061 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,05914728 0,09293132 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,05914728 0,09285216 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,05914728 0,09277313 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,05914728 0,09269425 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,05914728 0,09261549 ! vitamin transport GO:0051180 11 11 0,000 0,05914728 0,09253687 ! muscle maintenance GO:0046716 12 11 0,000 0,05914728 0,09245838 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,05914728 0,09238003 ! steroid catabolic process GO:0006706 11 11 0,000 0,05914728 0,09230181 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,05914728 0,09222372 ! muscle system process GO:0003012 72 72 1,000 0,05962347 0,09288763 ! sensory organ development GO:0007423 72 72 1,000 0,05962347 0,09280917 ! regulation of cytokine production GO:0001817 72 72 1,000 0,05962347 0,09273085 ! electron transport chain GO:0022900 75 74 1,000 0,06257763 0,09724332 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,06257763 0,0971614 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,06407335 0,09939999 ! response to oxidative stress GO:0006979 76 75 1,000 0,06407335 0,09931639 ! translational initiation GO:0006413 12 12 0,000 0,06435217 0,09966475 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06435217 0,09958107 ! initiation of viral infection GO:0019059 12 12 0,000 0,06435217 0,09949752 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06435217 0,09941412 ! iron ion transport GO:0006826 13 12 0,000 0,06435217 0,09933086 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06435217 0,09924774 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06435217 0,09916476 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06435217 0,09908191 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06435217 0,09899921 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06435217 0,09891664 ! collagen metabolic process GO:0032963 12 12 0,000 0,06435217 0,09883421 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06435217 0,09875191 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06435217 0,09866976 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06435217 0,09858774 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06435217 0,09850585 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06435217 0,09842411 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06435217 0,0983425 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,06435217 0,09826102 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06435217 0,09817968 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,06435217 0,09809847 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06435217 0,0980174 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06435217 0,09793646 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06435217 0,09785565 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06435217 0,09777498 ! acute-phase response GO:0006953 12 12 0,000 0,06435217 0,09769444 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06435217 0,09761403 ! vacuolar transport GO:0007034 12 12 0,000 0,06435217 0,09753376 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06435217 0,09745361 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06435217 0,0973736 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06435217 0,09729372 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06435217 0,09721397 ! male gonad development GO:0008584 12 12 0,000 0,06435217 0,09713436 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06435217 0,09705487 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06435217 0,09697551 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06435217 0,09689628 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06435217 0,09681718 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06435217 0,09673821 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06435217 0,09665937 ! cell fate determination GO:0001709 12 12 0,000 0,06435217 0,09658066 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,06435217 0,09650207 ! G1 phase GO:0051318 13 12 0,000 0,06435217 0,09642362 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06435217 0,09634529 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06435217 0,09626709 ! detection of light stimulus GO:0009583 13 12 0,000 0,06435217 0,09618901 ! synaptogenesis GO:0007416 12 12 0,000 0,06435217 0,09611106 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06435217 0,09603324 ! hormone transport GO:0009914 12 12 0,000 0,06435217 0,09595554 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06435217 0,09587797 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06435217 0,09580052 ! spermatid differentiation GO:0048515 13 12 0,000 0,06435217 0,0957232 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06435217 0,09564601 ! neural tube closure GO:0001843 13 12 0,000 0,06435217 0,09556894 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,06435217 0,09549199 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06435217 0,09541516 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,06435217 0,09533846 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,06710119 0,09933132 ! metal ion homeostasis GO:0055065 78 78 1,000 0,06863297 0,10151731 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,06952902 0,10276021 ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,06952902 0,10267787 ! phenol metabolic process GO:0018958 13 13 0,000 0,06952902 0,10259567 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,06952902 0,10251359 ! gluconeogenesis GO:0006094 13 13 0,000 0,06952902 0,10243164 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,06952902 0,10234983 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,06952902 0,10226815 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,06952902 0,10218659 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,06952902 0,10210517 ! regeneration GO:0031099 13 13 0,000 0,06952902 0,10202387 ! keratinization GO:0031424 13 13 0,000 0,06952902 0,10194271 ! post-embryonic development GO:0009791 14 13 0,000 0,06952902 0,10186167 ! patterning of blood vessels GO:0001569 13 13 0,000 0,06952902 0,10178077 ! vasculogenesis GO:0001570 13 13 0,000 0,06952902 0,10169999 ! regulation of innate immune response GO:0045088 13 13 0,000 0,06952902 0,10161934 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,06952902 0,10153882 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,06952902 0,10145842 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,06952902 0,10137815 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,06952902 0,10129801 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,06952902 0,101218 ! autophagy GO:0006914 13 13 0,000 0,06952902 0,10113811 ! receptor metabolic process GO:0043112 14 13 0,000 0,06952902 0,10105835 ! actin filament bundle formation GO:0051017 13 13 0,000 0,06952902 0,10097871 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,06952902 0,1008992 ! cell aging GO:0007569 13 13 0,000 0,06952902 0,10081982 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,06952902 0,10074056 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,06952902 0,10066142 ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,06952902 0,10058241 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,06952902 0,10050352 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,06952902 0,10042475 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,06952902 0,10034611 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,06952902 0,1002676 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,06952902 0,1001892 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,06952902 0,10011093 ! vasodilation GO:0042311 14 13 0,000 0,06952902 0,10003278 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,06952902 0,09995475 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,06952902 0,09987684 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,06952902 0,09979906 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,06952902 0,09972139 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,06952902 0,09964385 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,06952902 0,09956642 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,06952902 0,09948912 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,06952902 0,09941194 ! cell-cell junction organization GO:0045216 13 13 0,000 0,06952902 0,09933487 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,06952902 0,09925793 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,06952902 0,0991811 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,06952902 0,0991044 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,06952902 0,09902781 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,06952902 0,09895134 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,06952902 0,09887499 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,06952902 0,09879876 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,06952902 0,09872264 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,06952902 0,09864664 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,06952902 0,09857076 ! blastocyst development GO:0001824 13 13 0,000 0,06952902 0,09849499 ! telomere organization GO:0032200 13 13 0,000 0,06952902 0,09841934 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,06952902 0,09834381 ! regulation of amine transport GO:0051952 13 13 0,000 0,06952902 0,09826839 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,06952902 0,09819309 ! nuclear transport GO:0051169 79 79 1,000 0,07017644 0,09903153 GO:0006913|nucleocytoplasmic transport, ! neuron fate commitment GO:0048663 14 14 0,000 0,07467798 0,10530338 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,07467798 0,10522287 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,07467798 0,10514249 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,07467798 0,10506223 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,07467798 0,10498209 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,07467798 0,10490207 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,07467798 0,10482218 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,07467798 0,1047424 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,07467798 0,10466275 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,07467798 0,10458322 ! vesicle docking GO:0048278 14 14 0,000 0,07467798 0,10450381 ! superoxide metabolic process GO:0006801 15 14 0,000 0,07467798 0,10442452 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,07467798 0,10434535 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,07467798 0,1042663 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,07467798 0,10418737 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,07467798 0,10410856 ! hair cycle GO:0042633 14 14 0,000 0,07467798 0,10402987 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,07467798 0,1039513 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,07467798 0,10387284 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,07467798 0,10379451 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,07467798 0,10371629 ! lysosome organization GO:0007040 14 14 0,000 0,07467798 0,10363819 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,07467798 0,10356021 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,07467798 0,10348234 ! peptide transport GO:0015833 14 14 0,000 0,07467798 0,1034046 ! primary neural tube formation GO:0014020 15 14 0,000 0,07467798 0,10332696 ! peptide cross-linking GO:0018149 14 14 0,000 0,07467798 0,10324945 ! regulation of behavior GO:0050795 14 14 0,000 0,07467798 0,10317205 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,07467798 0,10309477 ! base-excision repair GO:0006284 14 14 0,000 0,07467798 0,1030176 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,07467798 0,10294055 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,07467798 0,10286362 ! formation of primary germ layer GO:0001704 14 14 0,000 0,07467798 0,10278679 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,07467798 0,10271009 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,07467798 0,1026335 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,07467798 0,10255702 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,07467798 0,10248065 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,07467798 0,1024044 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,07467798 0,10232827 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,07467798 0,10225224 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,07467798 0,10217633 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,07646376 0,10454207 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,07646376 0,10446457 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,07806314 0,10657064 ! regulation of cellular localization GO:0060341 86 85 1,000 0,07967321 0,10868818 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,07967321 0,10860779 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,07967321 0,10852752 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,07967321 0,10844736 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,07979919 0,10853868 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,07979919 0,10845864 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,07979919 0,10837871 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,07979919 0,1082989 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,07979919 0,10821921 ! response to vitamin GO:0033273 15 15 0,000 0,07979919 0,10813964 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,07979919 0,10806018 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,07979919 0,10798084 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,07979919 0,10790162 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,07979919 0,10782251 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,07979919 0,10774352 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,07979919 0,10766465 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,07979919 0,10758589 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,07979919 0,10750724 ! heme metabolic process GO:0042168 15 15 0,000 0,07979919 0,10742871 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,07979919 0,1073503 ! chromosome condensation GO:0030261 15 15 0,000 0,07979919 0,107272 ! response to starvation GO:0042594 15 15 0,000 0,07979919 0,10719381 ! response to ionizing radiation GO:0010212 16 15 0,000 0,07979919 0,10711574 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,07979919 0,10703778 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,07979919 0,10695993 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,07979919 0,1068822 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,07979919 0,10680458 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,07979919 0,10672708 ! phospholipid transport GO:0015914 15 15 0,000 0,07979919 0,10664968 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,07979919 0,1065724 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,07979919 0,10649523 ! glutathione metabolic process GO:0006749 16 15 0,000 0,07979919 0,10641817 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,07979919 0,10634122 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,07979919 0,10626439 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,07979919 0,10618766 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,07979919 0,10611105 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,07979919 0,10603454 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 0,000 0,07979919 0,10595815 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,07979919 0,10588186 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,08129382 0,10778742 ! hexose metabolic process GO:0019318 87 86 1,000 0,08129382 0,10770993 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,0848928 0,11239758 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,0848928 0,11231689 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,0848928 0,11223632 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,0848928 0,11215587 ! learning GO:0007612 16 16 0,000 0,0848928 0,11207552 ! circadian rhythm GO:0007623 16 16 0,000 0,0848928 0,1119953 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,0848928 0,11191519 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,0848928 0,11183519 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,0848928 0,11175531 ! vacuole organization GO:0007033 16 16 0,000 0,0848928 0,11167554 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,0848928 0,11159589 ! vesicle targeting GO:0006903 17 16 0,000 0,0848928 0,11151635 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,0848928 0,11143692 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,0848928 0,1113576 ! iron ion homeostasis GO:0055072 16 16 0,000 0,0848928 0,1112784 ! positive regulation of cell development GO:0010720 16 16 0,000 0,0848928 0,11119931 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,0848928 0,11112034 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,0848928 0,11104147 ! cell fate specification GO:0001708 16 16 0,000 0,0848928 0,11096272 ! pentose metabolic process GO:0019321 16 16 0,000 0,0848928 0,11088408 ! fatty acid transport GO:0015908 16 16 0,000 0,0848928 0,11080555 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,0848928 0,11072713 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,0848928 0,11064882 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,0848928 0,11057062 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,0848928 0,11049254 ! polyol metabolic process GO:0019751 16 16 0,000 0,0848928 0,11041456 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,0848928 0,11033669 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,0848928 0,11025894 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,0848928 0,11018129 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,0848928 0,11010375 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,0848928 0,11002632 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,0848928 0,109949 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,0848928 0,10987179 ! regulation of coagulation GO:0050818 17 16 0,000 0,0848928 0,10979469 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,08621729 0,1114295 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,08787847 0,11349686 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,08954942 0,11557393 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,08995895 0,11602124 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,08995895 0,11594011 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,08995895 0,11585909 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,08995895 0,11577818 ! leukocyte adhesion GO:0007159 17 17 0,000 0,08995895 0,11569738 ! sensory perception of smell GO:0007608 17 17 0,000 0,08995895 0,1156167 ! glucose transport GO:0015758 17 17 0,000 0,08995895 0,11553613 ! cell junction assembly GO:0034329 18 17 0,000 0,08995895 0,11545568 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,08995895 0,11537533 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,08995895 0,1152951 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,08995895 0,11521498 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,08995895 0,11513497 ! neural crest cell development GO:0014032 19 17 0,000 0,08995895 0,11505507 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,08995895 0,11497528 ! negative regulation of cell development GO:0010721 18 17 0,000 0,08995895 0,1148956 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,08995895 0,11481603 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,08995895 0,11473658 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,08995895 0,11465723 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,08995895 0,11457799 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,08995895 0,11449886 ! adult locomotory behavior GO:0008344 17 17 0,000 0,08995895 0,11441984 ! embryonic organ development GO:0048568 17 17 0,000 0,08995895 0,11434093 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,08995895 0,11426213 ! liver development GO:0001889 17 17 0,000 0,08995895 0,11418344 ! gene silencing GO:0016458 17 17 0,000 0,08995895 0,11410485 ! regulation of response to stress GO:0080134 97 94 1,000 0,09461929 0,11993353 ! blood vessel development GO:0001568 95 94 1,000 0,09461929 0,1198511 ! cofactor metabolic process GO:0051186 95 94 1,000 0,09461929 0,11976878 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09499779 0,12016536 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,09499779 0,12008295 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09499779 0,12000064 ! membrane docking GO:0022406 18 18 0,000 0,09499779 0,11991845 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09499779 0,11983637 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,09499779 0,1197544 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,09499779 0,11967255 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09499779 0,1195908 ! hexose transport GO:0008645 18 18 0,000 0,09499779 0,11950917 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09499779 0,11942765 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,09499779 0,11934624 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,09499779 0,11926494 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,09499779 0,11918375 ! ceramide metabolic process GO:0006672 18 18 0,000 0,09499779 0,11910268 GO:0046519|sphingoid metabolic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,09499779 0,11902171 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09499779 0,11894085 ! B cell differentiation GO:0030183 18 18 0,000 0,09499779 0,1188601 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,09499779 0,11877947 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,09499779 0,11869894 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,09499779 0,11861852 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09499779 0,11853821 ! vasculature development GO:0001944 97 96 1,000 0,09804525 0,12225805 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,10000946 0,12462302 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10000946 0,12453881 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10000946 0,12445472 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,10000946 0,12437074 ! regulation of pH GO:0006885 19 19 0,000 0,10000946 0,12428688 ! feeding behavior GO:0007631 19 19 0,000 0,10000946 0,12420313 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,10000946 0,12411949 ! peroxisome organization GO:0007031 19 19 0,000 0,10000946 0,12403596 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10000946 0,12395255 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,10000946 0,12386925 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10000946 0,12378606 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10000946 0,12370298 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10000946 0,12362002 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10000946 0,12353716 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10000946 0,12345442 ! eye morphogenesis GO:0048592 19 19 0,000 0,10000946 0,12337178 ! regulation of cell shape GO:0008360 21 19 0,000 0,10000946 0,12328926 ! placenta development GO:0001890 19 19 0,000 0,10000946 0,12320685 ! response to heat GO:0009408 19 19 0,000 0,10000946 0,12312454 ! vesicle localization GO:0051648 20 19 0,000 0,10000946 0,12304235 ! endocytosis GO:0006897 99 98 1,000 0,1015067 0,1248011 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 1,000 0,1015067 0,12471789 ! regulation of muscle development GO:0048634 21 20 0,000 0,10499411 0,12891682 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,10499411 0,12883099 ! negative regulation of binding GO:0051100 21 20 0,000 0,10499411 0,12874527 ! organic ether metabolic process GO:0018904 20 20 0,000 0,10499411 0,12865967 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,10499411 0,12857418 ! nucleus organization GO:0006997 20 20 0,000 0,10499411 0,12848881 ! phagocytosis GO:0006909 21 20 0,000 0,10499411 0,12840354 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,10499411 0,1283184 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,10499411 0,12823336 ! protein targeting to membrane GO:0006612 22 20 0,000 0,10499411 0,12814844 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,10499411 0,12806363 ! chromatin remodeling GO:0006338 20 20 0,000 0,10499411 0,12797893 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,10499411 0,12789434 ! lipid oxidation GO:0034440 20 20 0,000 0,10499411 0,12780987 GO:0019395|fatty acid oxidation, ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,10499411 0,12772551 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,10499411 0,12764125 ! RNA modification GO:0009451 20 20 0,000 0,10499411 0,12755711 ! single fertilization GO:0007338 21 20 0,000 0,10499411 0,12747308 ! regulation of B cell activation GO:0050864 20 20 0,000 0,10499411 0,12738917 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,10500247 0,12731549 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,10995187 0,13322899 ! mRNA catabolic process GO:0006402 21 21 0,000 0,10995187 0,13314145 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,10995187 0,13305403 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,10995187 0,13296673 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,10995187 0,13287954 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,10995187 0,13279246 ! Notch signaling pathway GO:0007219 22 21 0,000 0,10995187 0,1327055 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,10995187 0,13261865 ! ear morphogenesis GO:0042471 21 21 0,000 0,10995187 0,13253191 ! organic anion transport GO:0015711 21 21 0,000 0,10995187 0,13244529 ! cholesterol transport GO:0030301 21 21 0,000 0,10995187 0,13235878 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,10995187 0,13227238 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,10995187 0,1321861 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,10995187 0,13209993 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,10995187 0,13201387 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,10995187 0,13192792 ! regulation of proteolysis GO:0030162 21 21 0,000 0,10995187 0,13184209 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,10995187 0,13175637 ! RNA export from nucleus GO:0006405 22 22 0,000 0,11488288 0,1375758 ! sister chromatid segregation GO:0000819 22 22 0,000 0,11488288 0,13748646 ! regulation of ion transport GO:0043269 22 22 0,000 0,11488288 0,13739724 ! odontogenesis GO:0042476 22 22 0,000 0,11488288 0,13730814 ! cell junction organization GO:0034330 23 22 0,000 0,11488288 0,13721915 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,11488288 0,13713028 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,11488288 0,13704152 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,11488288 0,13695288 ! spindle organization GO:0007051 22 22 0,000 0,11488288 0,13686435 ! cell chemotaxis GO:0060326 23 22 0,000 0,11488288 0,13677594 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,11488288 0,13668764 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,11488288 0,13659945 ! male sex differentiation GO:0046661 22 22 0,000 0,11488288 0,13651138 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,11488288 0,13642342 ! detection of external stimulus GO:0009581 23 22 0,000 0,11488288 0,13633558 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,11488288 0,13624784 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,11488288 0,13616023 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,11488288 0,13607272 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,11488288 0,13598532 ! cytokine production GO:0001816 22 22 0,000 0,11488288 0,13589804 ! cytokinesis GO:0000910 23 22 0,000 0,11488288 0,13581087 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,11978729 0,14151794 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,11978729 0,14142728 ! viral infectious cycle GO:0019058 23 23 0,000 0,11978729 0,14133674 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,11978729 0,14124631 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,11978729 0,141156 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,11978729 0,1410658 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,11978729 0,14097572 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,11978729 0,14088576 ! endocrine system development GO:0035270 23 23 0,000 0,11978729 0,14079591 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,11978729 0,14070617 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,11978729 0,14061655 ! lipid homeostasis GO:0055088 23 23 0,000 0,11978729 0,14052704 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,11978729 0,14043765 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,11978729 0,14034837 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,11978729 0,1402592 ! mitochondrial transport GO:0006839 24 24 0,000 0,12466524 0,14587812 ! gliogenesis GO:0042063 24 24 0,000 0,12466524 0,14578556 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,12466524 0,14569311 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,12466524 0,14560078 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,12466524 0,14550857 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,12466524 0,14541648 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,12466524 0,1453245 ! fertilization GO:0009566 25 24 0,000 0,12466524 0,14523264 ! maintenance of protein location GO:0045185 25 24 0,000 0,12466524 0,14514089 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,12466524 0,14504927 ! glucan metabolic process GO:0044042 25 24 0,000 0,12466524 0,14495775 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,12951686 0,15050415 ! negative regulation of secretion GO:0051048 26 25 0,000 0,12951686 0,15040931 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,12951686 0,15031459 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,12951686 0,15022 ! cellular component disassembly GO:0022411 26 25 0,000 0,12951686 0,15012552 ! endosome transport GO:0016197 25 25 0,000 0,12951686 0,15003116 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,12951686 0,14993692 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,12951686 0,1498428 ! excretion GO:0007588 25 25 0,000 0,12951686 0,14974879 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,12951686 0,14965491 ! gastrulation GO:0007369 25 25 0,000 0,12951686 0,14956114 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,12951686 0,14946749 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,1343423 0,15493921 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,1343423 0,15484231 ! cellular defense response GO:0006968 26 26 0,000 0,1343423 0,15474553 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1343423 0,15464888 ! double-strand break repair GO:0006302 27 26 0,000 0,1343423 0,15455234 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1343423 0,15445593 ! germ cell development GO:0007281 27 26 0,000 0,1343423 0,15435963 ! maintenance of location in cell GO:0051651 27 26 0,000 0,1343423 0,15426346 ! chloride transport GO:0006821 27 27 0,000 0,13914168 0,15967504 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,13914168 0,15957568 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,13914168 0,15947644 ! learning or memory GO:0007611 28 27 0,000 0,13914168 0,15937733 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,13914168 0,15927834 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,13914168 0,15917947 ! peptide metabolic process GO:0006518 29 27 0,000 0,13914168 0,15908072 ! activation of caspase activity GO:0006919 27 27 0,000 0,13914168 0,1589821 ! mesenchymal cell development GO:0014031 29 27 0,000 0,13914168 0,15888359 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,13914168 0,15878521 ! defense response to bacterium GO:0042742 27 27 0,000 0,13914168 0,15868696 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,13914168 0,15858882 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,13914168 0,1584908 ! cell growth GO:0016049 27 27 0,000 0,13914168 0,15839291 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,14391516 0,1637257 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,14391516 0,1636247 ! carbohydrate transport GO:0008643 28 28 0,000 0,14391516 0,16352382 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,14391516 0,16342306 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,14391516 0,16332243 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,14391516 0,16322193 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,14866285 0,16850285 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,14866285 0,16839929 ! leukocyte migration GO:0050900 30 29 0,000 0,14866285 0,16829585 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,14866285 0,16819254 ! tRNA processing GO:0008033 29 29 0,000 0,14866285 0,16808935 ! adult behavior GO:0030534 30 29 0,000 0,14866285 0,16798629 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,14866285 0,16788336 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,14866285 0,16778055 ! transition metal ion transport GO:0000041 31 30 0,000 0,15338491 0,17300391 ! RNA catabolic process GO:0006401 30 30 0,000 0,15338491 0,1728981 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,15338491 0,17279242 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,15338491 0,17268686 GO:0043280|positive regulation of caspase activity, ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,15338491 0,17258144 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,15338491 0,17247614 ! response to temperature stimulus GO:0009266 30 30 0,000 0,15338491 0,17237097 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,15338491 0,17226593 ! vesicle organization GO:0016050 30 30 0,000 0,15338491 0,17216102 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,15338491 0,17205623 ! membrane fusion GO:0006944 31 31 0,000 0,15808146 0,17721663 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,15808146 0,1771089 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,15808146 0,1770013 ! ion transmembrane transport GO:0034220 31 31 0,000 0,15808146 0,17689383 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,15808146 0,17678649 ! digestion GO:0007586 31 31 0,000 0,15808146 0,17667928 ! regulation of heart contraction GO:0008016 31 31 0,000 0,15808146 0,1765722 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,15808146 0,17646525 ! extracellular matrix organization GO:0030198 31 31 0,000 0,15808146 0,17635844 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,15808146 0,17625175 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,15808146 0,17614518 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,16275264 0,18124055 ! cell redox homeostasis GO:0045454 32 32 0,000 0,16275264 0,18113111 ! lipid modification GO:0030258 32 32 0,000 0,16275264 0,1810218 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,16275264 0,18091262 ! cell maturation GO:0048469 32 32 0,000 0,16275264 0,18080357 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,16275264 0,18069465 ! negative regulation of cell size GO:0045792 33 33 0,000 0,16739858 0,18574087 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,16739858 0,18562911 ! amino acid transport GO:0006865 33 33 0,000 0,16739858 0,18551749 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,16739858 0,185406 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,16739858 0,18529465 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,16739858 0,18518342 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,16739858 0,18507234 ! regulation of actin filament length GO:0030832 34 34 0,000 0,17201942 0,19006702 ! response to metal ion GO:0010038 34 34 0,000 0,17201942 0,18995314 ! ear development GO:0043583 34 34 0,000 0,17201942 0,18983939 ! muscle cell differentiation GO:0042692 35 34 0,000 0,17201942 0,18972578 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,17201942 0,18961231 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,17201942 0,18949897 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,17201942 0,18938577 ! detection of stimulus GO:0051606 36 34 0,000 0,17201942 0,18927271 ! acute inflammatory response GO:0002526 35 35 0,000 0,17661528 0,19421358 ! regulation of cellular component size GO:0032535 35 35 0,000 0,17661528 0,19409777 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,17661528 0,19398209 ! mesoderm development GO:0007498 35 35 0,000 0,17661528 0,19386656 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,17661528 0,19375116 ! inorganic anion transport GO:0015698 35 35 0,000 0,17661528 0,1936359 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,17661528 0,19352078 ! regulation of immune effector process GO:0002697 35 35 0,000 0,17661528 0,1934058 ! hydrogen transport GO:0006818 36 36 0,000 0,18118629 0,19829355 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,18118629 0,19817587 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,18118629 0,19805833 ! regulation of mitosis GO:0007088 37 36 0,000 0,18118629 0,19794093 GO:0051783|regulation of nuclear division, ! female pregnancy GO:0007565 37 36 0,000 0,18118629 0,19782366 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,18118629 0,19770654 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,18118629 0,19758955 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,18118629 0,1974727 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,18118629 0,19735599 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,18118629 0,19723942 ! activation of immune response GO:0002253 36 36 0,000 0,18118629 0,19712299 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,1857326 0,20194996 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of growth GO:0045926 37 37 0,000 0,1857326 0,20183089 ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,1857326 0,20171195 ! positive regulation of secretion GO:0051047 39 38 0,000 0,19025433 0,20650101 ! neurotransmitter transport GO:0006836 40 38 0,000 0,19025433 0,20637947 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,19025433 0,20625807 ! exocytosis GO:0006887 40 38 0,000 0,19025433 0,20613682 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,19025433 0,2060157 ! chromosome segregation GO:0007059 38 38 0,000 0,19025433 0,20589473 ! RNA elongation GO:0006354 38 38 0,000 0,19025433 0,2057739 ! regulation of neurological system process GO:0031644 38 38 0,000 0,19025433 0,20565321 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,1947516 0,21039109 ! response to unfolded protein GO:0006986 39 39 0,000 0,1947516 0,21026784 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,1947516 0,21014473 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,1947516 0,21002176 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,1947516 0,20989894 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,1947516 0,20977627 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,1947516 0,20965374 ! developmental maturation GO:0021700 39 39 0,000 0,1947516 0,20953135 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,19922455 0,21421869 ! DNA catabolic process GO:0006308 41 40 0,000 0,19922455 0,21409378 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,2036733 0,21874702 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,2036733 0,21861962 ! amine catabolic process GO:0009310 42 41 0,000 0,2036733 0,21849237 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,2036733 0,21836526 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,2036733 0,21823831 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,2036733 0,2181115 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,20809798 0,22272043 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,20809798 0,22259117 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,20809798 0,22246205 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,20809798 0,22233309 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,20809798 0,22220428 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,20809798 0,22207561 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,21249873 0,22664071 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,21249873 0,22650963 ! humoral immune response GO:0006959 44 44 0,000 0,21687565 0,23104152 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,21687565 0,23090805 ! mRNA transport GO:0051028 44 44 0,000 0,21687565 0,23077473 ! protein import into nucleus GO:0006606 44 44 0,000 0,21687565 0,23064156 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,21687565 0,23050855 ! vitamin metabolic process GO:0006766 44 44 0,000 0,21687565 0,23037569 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,21687565 0,23024299 ! amine biosynthetic process GO:0009309 46 45 0,000 0,22122889 0,23472933 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,22122889 0,23459427 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,22122889 0,23445937 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,22122889 0,23432462 ! nuclear import GO:0051170 45 45 0,000 0,22122889 0,23419003 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,22122889 0,23405559 ! protein processing GO:0016485 45 45 0,000 0,22122889 0,23392131 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,22555856 0,23836263 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,22555856 0,23822603 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,22555856 0,23808959 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,22555856 0,23795331 ! amine transport GO:0015837 47 47 0,000 0,22986479 0,24235744 ! calcium ion transport GO:0006816 48 48 0,000 0,2341477 0,24673197 ! actin filament organization GO:0007015 50 48 0,000 0,2341477 0,24659098 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,2341477 0,24645015 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,2341477 0,24630948 ! protein localization in nucleus GO:0034504 48 48 0,000 0,2341477 0,24616898 ! ossification GO:0001503 50 49 0,000 0,23840742 0,25050449 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,23840742 0,25036175 ! divalent metal ion transport GO:0070838 49 49 0,000 0,23840742 0,25021918 ! response to nutrient GO:0007584 49 49 0,000 0,23840742 0,25007676 ! response to bacterium GO:0009617 50 49 0,000 0,23840742 0,24993451 ! regulation of ligase activity GO:0051340 50 49 0,000 0,23840742 0,24979242 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,23840742 0,2496505 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,23840742 0,24950873 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 50 50 0,000 0,24264406 0,25379853 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,24264406 0,25365457 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,24264406 0,25351078 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,24264406 0,25336714 ! transcription initiation GO:0006352 50 50 0,000 0,24264406 0,25322367 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,24685776 0,25747529 ! positive regulation of immune response GO:0050778 51 51 0,000 0,24685776 0,25732966 ! rRNA metabolic process GO:0016072 51 51 0,000 0,24685776 0,2571842 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,24685776 0,2570389 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,24685776 0,25689376 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,24685776 0,25674878 ! RNA localization GO:0006403 52 52 0,000 0,25104862 0,2609603 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,25104862 0,26081319 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,25104862 0,26066626 ! cell fate commitment GO:0045165 52 52 0,000 0,25104862 0,26051949 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,25104862 0,26037288 ! sodium ion transport GO:0006814 53 53 0,000 0,25521677 0,26454697 ! tRNA metabolic process GO:0006399 53 53 0,000 0,25521677 0,26439826 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,25521677 0,26424973 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,25521677 0,26410136 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,25936234 0,26824062 ! response to virus GO:0009615 54 54 0,000 0,25936234 0,26809018 ! hormone metabolic process GO:0042445 55 54 0,000 0,25936234 0,2679399 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,25936234 0,2677898 ! nucleosome organization GO:0034728 55 55 0,000 0,26348543 0,27189454 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,26348543 0,27174239 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,26348543 0,27159041 ! in utero embryonic development GO:0001701 55 55 0,000 0,26348543 0,2714386 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,26758617 0,27550911 ! ATP metabolic process GO:0046034 57 57 0,000 0,27166468 0,2795522 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,27166468 0,2793962 ! innate immune response GO:0045087 58 58 0,000 0,27572107 0,28340988 ! dephosphorylation GO:0016311 60 59 0,000 0,27975545 0,28739649 ! carboxylic acid transport GO:0046942 59 59 0,000 0,27975545 0,28723638 GO:0015849|organic acid transport, ! protein localization in organelle GO:0033365 59 59 0,000 0,27975545 0,28707645 ! potassium ion transport GO:0006813 60 60 0,000 0,28376796 0,29103191 ! protein polymerization GO:0051258 65 60 0,000 0,28376796 0,29087005 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,28775869 0,29479671 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,28775869 0,29463293 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,29172778 0,29853098 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,29172778 0,29836531 ! protein import GO:0017038 62 62 0,000 0,29172778 0,29819983 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,29172778 0,29803453 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,29567532 0,30190006 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,29567532 0,3017329 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,29960144 0,30557025 ! angiogenesis GO:0001525 65 64 0,000 0,29960144 0,30540124 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,29960144 0,30523242 ! anion transport GO:0006820 65 65 0,000 0,30350624 0,30903978 ! regulation of hormone levels GO:0010817 66 65 0,000 0,30350624 0,30886913 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,30738984 0,31264872 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,30738984 0,31247627 ! DNA packaging GO:0006323 66 66 0,000 0,30738984 0,31230401 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,30738984 0,31213195 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,31125236 0,31588001 ! muscle contraction GO:0006936 67 67 0,000 0,31125236 0,31570616 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,3150939 0,31942687 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,3150939 0,31925127 ! sensory perception of sound GO:0007605 71 69 0,000 0,31891457 0,32294481 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 0,000 0,31891457 0,32276747 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,31891457 0,32259032 ! translational elongation GO:0006414 71 71 0,000 0,32649377 0,3300757 ! ribosome biogenesis GO:0042254 71 71 0,000 0,32649377 0,32989474 ! secretion by cell GO:0032940 75 72 0,000 0,3302525 0,33350979 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,3302525 0,33332714 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,34140658 0,34439645 ! microtubule-based movement GO:0007018 82 78 0,000 0,3523797 0,35527122 ! regulation of immune response GO:0050776 78 78 0,000 0,3523797 0,35507697 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,35959599 0,3621505 ! lipid catabolic process GO:0016042 82 81 0,000 0,36317472 0,3655549 ! ncRNA processing GO:0034470 83 83 0,000 0,37027386 0,37249712 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,38077829 0,38285564 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,38768625 0,38958874 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,38768625 0,38937643 ! chemotaxis GO:0006935 90 89 0,000 0,39111203 0,3926032 GO:0042330|taxis, ! negative regulation of cell cycle GO:0045786 92 91 0,000 0,3979077 0,39920735 ! DNA replication GO:0006260 91 91 0,000 0,3979077 0,39899015 ! visual perception GO:0007601 93 92 0,000 0,40127779 0,40215061 GO:0050953|sensory perception of light stimulus, ! positive regulation of immune system process GO:0002684 92 92 0,000 0,40127779 0,40193205 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,42111593 0,42157342 ! anti-apoptosis GO:0006916 100 99 0,000 0,42435946 0,42458984 ! response to other organism GO:0051707 101 100 0,000 0,42758528 0,42758528