pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6111-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! filopodium assembly GO:0046847 32 16 3,000 1,232E-06 2,964E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 4,000 1,376E-06 1,655E-03 ! microspike assembly GO:0030035 36 17 3,000 1,604E-06 1,287E-03 ! nuclear migration GO:0007097 12 6 2,000 2,748E-06 1,653E-03 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,748E-06 1,322E-03 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 4,79E-06 1,921E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 4,79E-06 1,646E-03 ! macrophage differentiation GO:0030225 11 7 2,000 4,79E-06 1,441E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 7,635E-06 2,041E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 7,635E-06 1,837E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 9,716E-06 2,125E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,141E-05 2,287E-03 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 1,219E-05 2,255E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 2,224E-05 3,822E-03 ! nucleus localization GO:0051647 19 11 2,000 2,224E-05 3,567E-03 ! cell projection assembly GO:0030031 120 66 4,000 2,497E-05 3,755E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,954E-05 4,18E-03 ! histone acetylation GO:0016573 26 12 2,000 2,954E-05 3,948E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 2,954E-05 3,74E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 4,105E-05 4,938E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 4,85E-05 5,557E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 4,85E-05 5,304E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 29 14 2,000 4,85E-05 5,073E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 4,85E-05 4,862E-03 ! activation of protein kinase activity GO:0032147 147 79 4,000 5,964E-05 5,74E-03 ! positive regulation of biomineral formation GO:0070169 30 15 2,000 6,039E-05 5,589E-03 ! dorsal/ventral pattern formation GO:0009953 68 41 3,000 6,193E-05 5,519E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 7,131E-05 6,127E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 8,966E-05 7,438E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 9,78E-05 7,843E-03 ! proximal/distal pattern formation GO:0009954 32 19 2,000 1,267E-04 9,83E-03 ! positive regulation of ossification GO:0045778 47 20 2,000 1,484E-04 0,01116081 ! protein amino acid acetylation GO:0006473 39 20 2,000 1,484E-04 0,01082261 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,484E-04 0,01050429 ! negative regulation of translation GO:0017148 29 20 2,000 1,484E-04 0,01020417 ! positive regulation of growth GO:0045927 90 52 3,000 1,584E-04 0,01058332 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 1,725E-04 0,01121834 ! cell cycle arrest GO:0007050 213 100 4,000 1,825E-04 0,01155465 ! aging GO:0007568 103 55 3,000 1,971E-04 0,01215871 ! positive regulation of bone remodeling GO:0046852 51 22 2,000 1,99E-04 0,01196954 GO:0034105|positive regulation of tissue remodeling, ! ureteric bud development GO:0001657 43 22 2,000 1,99E-04 0,0116776 ! regulation of DNA replication GO:0006275 101 56 3,000 2,114E-04 0,01210966 ! positive regulation of cell migration GO:0030335 126 57 3,000 2,264E-04 0,01266941 ! positive regulation of DNA replication GO:0045740 43 23 2,000 2,28E-04 0,01246583 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,28E-04 0,01218881 ! regulation of bone mineralization GO:0030500 49 23 2,000 2,28E-04 0,01192383 ! skeletal system morphogenesis GO:0048705 105 59 3,000 2,588E-04 0,01324771 ! positive regulation of helicase activity GO:0051096 11 5 1,000 2,673E-04 0,01339656 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,673E-04 0,01312316 ! protein maturation by protein folding GO:0022417 13 5 1,000 2,673E-04 0,01286069 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,673E-04 0,01260852 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,673E-04 0,01236605 ! valine metabolic process GO:0006573 10 5 1,000 2,673E-04 0,01213273 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 2,673E-04 0,01190805 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,673E-04 0,01169154 ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 2,673E-04 0,01148276 ! neural tube patterning GO:0021532 7 5 1,000 2,673E-04 0,01128131 ! sequestering of calcium ion GO:0051208 7 5 1,000 2,673E-04 0,01108681 ! phospholipid scrambling GO:0017121 8 5 1,000 2,673E-04 0,01089889 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 2,762E-04 0,01107379 ! kidney development GO:0001822 122 60 3,000 2,762E-04 0,01089225 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 2,938E-04 0,0114017 ! interaction with host GO:0051701 62 25 2,000 2,938E-04 0,01122072 ! regulation of biomineral formation GO:0070167 51 25 2,000 2,938E-04 0,01104539 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 2,943E-04 0,01089519 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 3,309E-04 0,01206153 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 3,309E-04 0,01188151 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 3,333E-04 0,0117919 ! positive regulation of cell motion GO:0051272 146 64 3,000 3,541E-04 0,01234579 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,708E-04 0,01274503 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 3,708E-04 0,01256552 ! protein amino acid acylation GO:0043543 55 27 2,000 3,708E-04 0,012391 ! fatty acid biosynthetic process GO:0006633 124 66 3,000 3,984E-04 0,0131303 ! cGMP-mediated signaling GO:0019934 13 6 1,000 3,995E-04 0,01298982 ! thymic T cell selection GO:0045061 12 6 1,000 3,995E-04 0,01281662 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 3,995E-04 0,01264798 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! male sex determination GO:0030238 15 6 1,000 3,995E-04 0,01248372 ! neural nucleus development GO:0048857 14 6 1,000 3,995E-04 0,01232367 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 3,995E-04 0,01216768 ! determination of adult lifespan GO:0008340 15 6 1,000 3,995E-04 0,01201558 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 4,137E-04 0,01228888 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 4,22E-04 0,01238127 ! negative regulation of kinase activity GO:0033673 131 68 3,000 4,465E-04 0,01294427 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 4,597E-04 0,0131669 ! sterol biosynthetic process GO:0016126 52 29 2,000 4,597E-04 0,013012 ! urogenital system development GO:0001655 137 69 3,000 4,721E-04 0,01320812 ! appendage morphogenesis GO:0035107 135 70 3,000 4,987E-04 0,01379185 GO:0035108|limb morphogenesis, ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 2,000 5,088E-04 0,01391166 ! appendage development GO:0048736 136 71 3,000 5,264E-04 0,0142293 GO:0060173|limb development, ! negative regulation of transferase activity GO:0051348 140 72 3,000 5,551E-04 0,01483896 ! regulation of helicase activity GO:0051095 15 7 1,000 5,574E-04 0,01473775 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,574E-04 0,01457755 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 5,574E-04 0,01442081 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 5,574E-04 0,01426739 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,574E-04 0,01411721 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 5,574E-04 0,01397016 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 5,574E-04 0,01382613 ! regulation of meiosis GO:0040020 12 7 1,000 5,574E-04 0,01368505 GO:0051445|regulation of meiotic cell cycle, ! regulation of respiratory burst GO:0060263 11 7 1,000 5,574E-04 0,01354682 ! muscle adaptation GO:0043500 14 7 1,000 5,574E-04 0,01341135 ! metanephros development GO:0001656 74 32 2,000 6,169E-04 0,01469534 ! BMP signaling pathway GO:0030509 64 32 2,000 6,169E-04 0,01455126 ! hindbrain development GO:0030902 61 32 2,000 6,169E-04 0,01440999 ! positive regulation of catabolic process GO:0009896 64 32 2,000 6,169E-04 0,01427143 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 7,386E-04 0,01692414 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 7,407E-04 0,01681185 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 7,407E-04 0,01665473 GO:0016446|somatic hypermutation of immunoglobulin genes, ! succinate metabolic process GO:0006105 14 8 1,000 7,407E-04 0,01650052 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,407E-04 0,01634914 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,407E-04 0,01620051 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 7,407E-04 0,01605456 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 7,407E-04 0,01591122 ! multicellular organismal aging GO:0010259 18 8 1,000 7,407E-04 0,01577041 ! regulation of developmental growth GO:0048638 15 9 1,000 9,49E-04 0,02002959 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,49E-04 0,01985542 ! regulation of glycolysis GO:0006110 21 9 1,000 9,49E-04 0,01968425 ! keratinocyte proliferation GO:0043616 14 9 1,000 9,49E-04 0,01951601 ! microtubule bundle formation GO:0001578 21 9 1,000 9,49E-04 0,01935062 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,49E-04 0,01918801 ! T cell selection GO:0045058 23 9 1,000 9,49E-04 0,01902811 ! phosphagen metabolic process GO:0006599 12 9 1,000 9,49E-04 0,01887085 GO:0006600|creatine metabolic process, ! motor axon guidance GO:0008045 16 9 1,000 9,49E-04 0,01871617 ! protein heterooligomerization GO:0051291 16 9 1,000 9,49E-04 0,01856401 ! retinal ganglion cell axon guidance GO:0031290 13 9 1,000 9,49E-04 0,0184143 ! musculoskeletal movement GO:0050881 14 9 1,000 9,49E-04 0,01826698 GO:0050879|multicellular organismal movement, ! regulation of telomere maintenance GO:0032204 14 9 1,000 9,49E-04 0,01812201 ! pyrimidine base metabolic process GO:0006206 17 9 1,000 9,49E-04 0,01797931 ! regulation of muscle adaptation GO:0043502 14 9 1,000 9,49E-04 0,01783885 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,025E-03 0,01912611 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,182E-03 0,02188039 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,182E-03 0,02171336 ! nucleobase biosynthetic process GO:0046112 24 10 1,000 1,182E-03 0,02154887 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,182E-03 0,02138685 GO:0045685|regulation of glial cell differentiation, ! positive regulation of phagocytosis GO:0050766 13 10 1,000 1,182E-03 0,02122724 ! midbrain development GO:0030901 13 10 1,000 1,182E-03 0,02107 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,182E-03 0,02091508 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,182E-03 0,02076241 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 1,374E-03 0,02396206 GO:0090047|positive regulation of transcription regulator activity, ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,44E-03 0,02492561 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,44E-03 0,02474757 ! blood vessel remodeling GO:0001974 29 11 1,000 1,44E-03 0,02457206 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 1,44E-03 0,02439902 ! DNA methylation GO:0006306 19 11 1,000 1,44E-03 0,02422839 GO:0006305|DNA alkylation, ! nitric oxide mediated signal transduction GO:0007263 23 11 1,000 1,44E-03 0,02406014 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 1,44E-03 0,02389421 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cardiac cell differentiation GO:0035051 31 11 1,000 1,44E-03 0,02373055 ! sequestering of metal ion GO:0051238 14 11 1,000 1,44E-03 0,02356912 ! lamellipodium assembly GO:0030032 20 11 1,000 1,44E-03 0,02340987 ! regulation of embryonic development GO:0045995 27 11 1,000 1,44E-03 0,02325275 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,448E-03 0,02321978 ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 1,566E-03 0,02494881 ! developmental growth GO:0048589 82 44 2,000 1,574E-03 0,0249075 ! leukocyte differentiation GO:0002521 202 96 3,000 1,627E-03 0,02559023 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,68E-03 0,02623998 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,722E-03 0,02673148 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 1,722E-03 0,02656012 ! virus-host interaction GO:0019048 29 12 1,000 1,722E-03 0,02639095 ! cartilage condensation GO:0001502 20 12 1,000 1,722E-03 0,02622392 ! hippocampus development GO:0021766 26 12 1,000 1,722E-03 0,02605899 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,722E-03 0,02589612 ! entry into host cell GO:0030260 32 12 1,000 1,722E-03 0,02573527 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 16 12 1,000 1,722E-03 0,02557641 ! cranial nerve development GO:0021545 20 12 1,000 1,722E-03 0,0254195 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 1,722E-03 0,0252645 ! autonomic nervous system development GO:0048483 24 12 1,000 1,722E-03 0,02511139 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,722E-03 0,02496011 GO:0042130|negative regulation of T cell proliferation, ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,79E-03 0,02578723 ! pigmentation GO:0043473 100 46 2,000 1,79E-03 0,02563374 ! skeletal muscle tissue development GO:0007519 186 99 3,000 1,822E-03 0,02593853 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA binding GO:0043388 73 47 2,000 1,905E-03 0,02695662 ! JNK cascade GO:0007254 91 47 2,000 1,905E-03 0,02679898 ! plasma membrane organization GO:0007009 24 13 1,000 2,028E-03 0,02837202 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,028E-03 0,02820801 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,028E-03 0,0280459 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,028E-03 0,02788564 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 2,028E-03 0,0277272 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 2,000 2,148E-03 0,02919479 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,276E-03 0,03076664 ! regulation of ossification GO:0030278 117 50 2,000 2,276E-03 0,03059476 ! histone modification GO:0016570 91 50 2,000 2,276E-03 0,03042478 ! retina development in camera-type eye GO:0060041 27 14 1,000 2,358E-03 0,03134735 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,358E-03 0,03117511 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 1,000 2,358E-03 0,03100475 ! negative regulation of caspase activity GO:0043154 22 14 1,000 2,358E-03 0,03083625 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,358E-03 0,03066957 ! positive regulation of binding GO:0051099 78 51 2,000 2,409E-03 0,03116489 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 2,409E-03 0,03099824 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 2,409E-03 0,03083335 ! covalent chromatin modification GO:0016569 101 52 2,000 2,547E-03 0,03242456 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 2,547E-03 0,0322539 ! cartilage development GO:0051216 90 52 2,000 2,547E-03 0,03208504 ! synapse organization GO:0050808 85 52 2,000 2,547E-03 0,03191793 ! positive regulation of cell size GO:0045793 27 15 1,000 2,712E-03 0,03380528 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 1,000 2,712E-03 0,03363102 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,712E-03 0,03345856 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 2,712E-03 0,03328785 ! heart morphogenesis GO:0003007 97 55 2,000 2,989E-03 0,03650993 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,089E-03 0,03753045 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,089E-03 0,03734185 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,089E-03 0,03715514 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,089E-03 0,03697029 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 3,089E-03 0,03678727 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,089E-03 0,03660605 GO:0031114|regulation of microtubule depolymerization, ! regulation of dephosphorylation GO:0035303 43 16 1,000 3,089E-03 0,03642661 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,089E-03 0,03624892 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of bone remodeling GO:0046850 137 57 2,000 3,309E-03 0,03864622 ! regulation of tissue remodeling GO:0034103 140 58 2,000 3,476E-03 0,04040375 ! limbic system development GO:0021761 36 17 1,000 3,488E-03 0,04035144 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 3,488E-03 0,04015837 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,488E-03 0,03996714 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 3,488E-03 0,03977772 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 1,000 3,488E-03 0,03959009 ! nucleobase metabolic process GO:0009112 37 17 1,000 3,488E-03 0,03940422 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,488E-03 0,03922009 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 3,488E-03 0,03903767 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 3,488E-03 0,03885694 ! establishment of organelle localization GO:0051656 109 59 2,000 3,648E-03 0,04045285 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 3,826E-03 0,04222621 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,911E-03 0,0429682 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 3,911E-03 0,04277289 GO:0050886|endocrine process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 3,911E-03 0,04257935 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 3,911E-03 0,04238755 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 3,911E-03 0,04219747 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 3,911E-03 0,04200909 ! nerve development GO:0021675 28 18 1,000 3,911E-03 0,04182238 ! regulation of protein complex assembly GO:0043254 117 61 2,000 4,009E-03 0,04267619 ! viral reproductive process GO:0022415 126 62 2,000 4,197E-03 0,04447972 ! regulation of homeostatic process GO:0032844 134 62 2,000 4,197E-03 0,04428463 ! skin development GO:0043588 36 19 1,000 4,356E-03 0,04576964 ! lipid phosphorylation GO:0046834 35 19 1,000 4,356E-03 0,04557064 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,356E-03 0,04537337 ! forelimb morphogenesis GO:0035136 32 19 1,000 4,356E-03 0,04517779 ! cerebral cortex development GO:0021987 36 19 1,000 4,356E-03 0,0449839 ! neuromuscular junction development GO:0007528 34 19 1,000 4,356E-03 0,04479166 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,356E-03 0,04460106 ! protein export from nucleus GO:0006611 36 19 1,000 4,356E-03 0,04441207 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 4,356E-03 0,04422468 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 4,356E-03 0,04403886 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 4,39E-03 0,044191 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 4,792E-03 0,04803995 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 2,000 4,792E-03 0,04784062 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 4,824E-03 0,04795929 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 4,824E-03 0,04776193 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 4,824E-03 0,04756618 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 4,824E-03 0,04737203 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 1,000 4,824E-03 0,04717946 ! negative regulation of T cell activation GO:0050868 40 20 1,000 4,824E-03 0,04698845 ! activation of MAPK activity GO:0000187 115 67 2,000 5,216E-03 0,05060253 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 5,216E-03 0,05039931 ! ovarian follicle development GO:0001541 35 21 1,000 5,313E-03 0,05113662 ! inactivation of MAPK activity GO:0000188 39 21 1,000 5,313E-03 0,05093289 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,313E-03 0,05073078 ! cell aging GO:0007569 44 21 1,000 5,313E-03 0,05053026 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 5,313E-03 0,05033132 ! regulation of vasoconstriction GO:0019229 39 21 1,000 5,313E-03 0,05013394 ! oogenesis GO:0048477 36 21 1,000 5,313E-03 0,04993811 ! DNA modification GO:0006304 34 21 1,000 5,313E-03 0,0497438 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 5,313E-03 0,04955099 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 5,313E-03 0,04935967 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 5,436E-03 0,05030402 ! viral reproduction GO:0016032 134 68 2,000 5,436E-03 0,05011129 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 5,825E-03 0,05349119 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 5,825E-03 0,05328781 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 5,825E-03 0,05308596 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 5,825E-03 0,05288563 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 5,825E-03 0,05268682 ! apoptotic nuclear changes GO:0030262 32 22 1,000 5,825E-03 0,05248949 ! renal system process GO:0003014 41 22 1,000 5,825E-03 0,05229363 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 5,825E-03 0,05209923 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,825E-03 0,05190627 ! protein stabilization GO:0050821 39 22 1,000 5,825E-03 0,05171473 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 6,358E-03 0,05623966 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,358E-03 0,05603366 ! regulation of DNA recombination GO:0000018 48 23 1,000 6,358E-03 0,05582915 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,358E-03 0,05562614 ! sex determination GO:0007530 47 23 1,000 6,358E-03 0,05542459 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 6,358E-03 0,05522451 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 1,000 6,358E-03 0,05502586 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 6,358E-03 0,05482863 GO:0006099|tricarboxylic acid cycle, ! regulation of caspase activity GO:0043281 122 72 2,000 6,372E-03 0,05475322 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 6,372E-03 0,05455837 ! axon guidance GO:0007411 139 73 2,000 6,62E-03 0,05648096 ! regulation of transcription factor activity GO:0051090 126 74 2,000 6,874E-03 0,05843825 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 6,874E-03 0,05823248 ! eye development GO:0001654 143 74 2,000 6,874E-03 0,05802815 ! organelle localization GO:0051640 136 74 2,000 6,874E-03 0,05782526 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 6,912E-03 0,05794799 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 6,912E-03 0,05774678 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 1,000 6,912E-03 0,05754696 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 6,912E-03 0,05734853 ! pallium development GO:0021543 49 24 1,000 6,912E-03 0,05715145 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 6,912E-03 0,05695573 ! protein tetramerization GO:0051262 52 24 1,000 6,912E-03 0,05676134 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 7,133E-03 0,05837468 ! steroid biosynthetic process GO:0006694 131 76 2,000 7,398E-03 0,06033933 ! regulation of catabolic process GO:0009894 161 76 2,000 7,398E-03 0,06013548 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 7,488E-03 0,0606592 ! myelination GO:0042552 45 25 1,000 7,488E-03 0,06045565 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 7,488E-03 0,06025345 ! coenzyme catabolic process GO:0009109 39 25 1,000 7,488E-03 0,06005261 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 7,488E-03 0,0598531 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 7,488E-03 0,05965491 ! immunoglobulin production GO:0002377 55 25 1,000 7,488E-03 0,05945803 GO:0002440|production of molecular mediator of immune response, ! initiation of viral infection GO:0019059 57 26 1,000 8,084E-03 0,06398276 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 8,084E-03 0,06377298 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 8,084E-03 0,06356457 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 8,084E-03 0,06335752 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 8,084E-03 0,06315182 ! cellular response to oxidative stress GO:0034599 39 26 1,000 8,084E-03 0,06294744 ! somatic diversification of immune receptors GO:0002200 56 26 1,000 8,084E-03 0,06274438 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 8,228E-03 0,06365757 ! regulation of peptidase activity GO:0052547 134 79 2,000 8,228E-03 0,06345354 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 8,228E-03 0,06325081 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 8,701E-03 0,0666734 ! regulation of chromosome organization GO:0033044 42 27 1,000 8,701E-03 0,06646174 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 8,701E-03 0,06625142 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 8,701E-03 0,06604242 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 8,811E-03 0,06666479 GO:0045937|positive regulation of phosphate metabolic process, ! dendrite development GO:0016358 59 28 1,000 9,339E-03 0,07043667 ! negative regulation of protein modification process GO:0031400 60 28 1,000 9,339E-03 0,07021656 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 9,339E-03 0,06999781 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 9,339E-03 0,06978043 ! synaptogenesis GO:0007416 42 28 1,000 9,339E-03 0,06956439 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 9,997E-03 0,07423384 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 9,997E-03 0,07400542 ! tissue homeostasis GO:0001894 48 29 1,000 9,997E-03 0,07377841 GO:0048871|multicellular organismal homeostasis, ! tube morphogenesis GO:0035239 176 86 2,000 0,01037143 0,07631089 ! mitochondrion organization GO:0007005 148 86 2,000 0,01037143 0,07607824 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01067427 0,07806171 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01067427 0,07782515 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 1,000 0,01067427 0,07759003 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01067427 0,07735633 ! cellular respiration GO:0045333 135 88 2,000 0,01103753 0,07974861 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01103753 0,07950985 ! regulation of DNA binding GO:0051101 155 88 2,000 0,01103753 0,0792725 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01137173 0,08142969 ! ovulation cycle process GO:0022602 49 31 1,000 0,01137173 0,08118806 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01137173 0,08094786 ! sterol metabolic process GO:0016125 152 91 2,000 0,0120821 0,08575085 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,01208872 0,08554545 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01208872 0,08529458 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01208872 0,08504518 ! ovulation cycle GO:0042698 51 32 1,000 0,01208872 0,08479724 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01208872 0,08455073 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01280897 0,08932867 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01282502 0,08918208 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01282502 0,08892508 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01358042 0,09389224 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01358042 0,09362321 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 0,01358042 0,09335571 ! mismatch repair GO:0006298 46 34 1,000 0,01358042 0,09308974 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 0,01358042 0,09282528 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01435471 0,09783973 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01435471 0,09756335 ! odontogenesis GO:0042476 66 35 1,000 0,01435471 0,09728852 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01435471 0,09701524 ! female gonad development GO:0008585 58 35 1,000 0,01435471 0,09674349 ! telencephalon development GO:0021537 68 35 1,000 0,01435471 0,09647325 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01435471 0,09620452 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01435471 0,09593729 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01514766 0,1009564 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 0,01514766 0,10067752 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01514766 0,10040017 ! aerobic respiration GO:0009060 55 36 1,000 0,01514766 0,10012434 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01514766 0,09985003 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01514766 0,09957721 ! meiosis I GO:0007127 65 37 1,000 0,01595906 0,10462533 ! tissue remodeling GO:0048771 76 37 1,000 0,01595906 0,10434102 ! regulation of protein stability GO:0031647 73 37 1,000 0,01595906 0,10405825 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,0167887 0,10917194 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,0167887 0,10887768 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,0167887 0,108585 ! mammary gland development GO:0030879 86 39 1,000 0,01763638 0,11376173 ! ear morphogenesis GO:0042471 60 39 1,000 0,01763638 0,11345756 ! segmentation GO:0035282 67 39 1,000 0,01763638 0,11315501 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01763638 0,11285406 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01850188 0,1180783 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,01850188 0,11776593 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01850188 0,1174552 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,01850188 0,11714611 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,019385 0,12241549 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,019385 0,12209503 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,019385 0,12177625 ! T cell differentiation GO:0030217 81 41 1,000 0,019385 0,12145912 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,019385 0,12114364 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,019385 0,1208298 ! female gamete generation GO:0007292 61 41 1,000 0,019385 0,12051758 ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02028553 0,12579118 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02028553 0,12546781 ! regulation of tube size GO:0035150 71 42 1,000 0,02028553 0,1251461 GO:0050880|regulation of blood vessel size, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02028553 0,12482603 ! neuron migration GO:0001764 79 42 1,000 0,02028553 0,1245076 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02120327 0,12980932 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02120327 0,12947985 ! neural tube development GO:0021915 77 43 1,000 0,02120327 0,12915206 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,02120327 0,12882592 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02213802 0,13416642 ! biopolymer methylation GO:0043414 84 44 1,000 0,02213802 0,13382932 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02213802 0,13349391 ! glycolysis GO:0006096 65 45 1,000 0,02308957 0,13888379 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02308957 0,13853744 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02308957 0,13819282 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 0,02308957 0,13784991 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 0,02405774 0,14327457 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02405774 0,14292081 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02405774 0,14256878 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02405774 0,14221849 ! positive regulation of defense response GO:0031349 76 47 1,000 0,02504232 0,14767605 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02504232 0,14731498 ! methylation GO:0032259 90 47 1,000 0,02504232 0,14695568 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02579637 0,15101231 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02579637 0,15064578 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02579637 0,15028102 ! neuron fate determination GO:0048664 7 5 0,000 0,02579637 0,14991802 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02579637 0,14955677 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02579637 0,14919726 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02579637 0,14883947 ! polyol transport GO:0015791 12 5 0,000 0,02579637 0,1484834 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02579637 0,14812902 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02579637 0,14777633 ! response to superoxide GO:0000303 10 5 0,000 0,02579637 0,14742532 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02579637 0,14707597 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02579637 0,14672827 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02579637 0,14638222 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02579637 0,14603779 ! female meiosis GO:0007143 7 5 0,000 0,02579637 0,14569498 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02579637 0,14535377 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02579637 0,14501416 ! cobalt ion transport GO:0006824 11 5 0,000 0,02579637 0,14467613 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02579637 0,14433967 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02579637 0,14400478 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02579637 0,14367144 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02579637 0,14333963 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02579637 0,14300935 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02579637 0,1426806 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02579637 0,14235335 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02579637 0,1420276 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02579637 0,14170333 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02579637 0,14138055 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02579637 0,14105923 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02579637 0,14073936 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02579637 0,14042095 ! negative chemotaxis GO:0050919 14 5 0,000 0,02579637 0,14010397 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02579637 0,13978842 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02579637 0,13947429 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02579637 0,13916157 ! behavioral response to pain GO:0048266 9 5 0,000 0,02579637 0,13885025 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02579637 0,13854031 ! Notch receptor processing GO:0007220 8 5 0,000 0,02579637 0,13823176 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02579637 0,13792458 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02579637 0,13761876 ! micturition GO:0060073 9 5 0,000 0,02579637 0,13731429 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02579637 0,13701117 ! copulation GO:0007620 9 5 0,000 0,02579637 0,13670938 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02579637 0,13640892 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02579637 0,13610978 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02579637 0,13581195 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02579637 0,13551541 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02579637 0,13522017 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02579637 0,13492622 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02579637 0,13463354 ! grooming behavior GO:0007625 6 5 0,000 0,02579637 0,13434212 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02579637 0,13405197 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02579637 0,13376306 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02579637 0,1334754 ! response to protozoan GO:0001562 10 5 0,000 0,02579637 0,13318897 ! lymph vessel development GO:0001945 10 5 0,000 0,02579637 0,13290377 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02579637 0,13261979 ! endochondral ossification GO:0001958 16 5 0,000 0,02579637 0,13233701 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02579637 0,13205545 ! parathyroid gland development GO:0060017 13 5 0,000 0,02579637 0,13177507 ! anagen GO:0042640 6 5 0,000 0,02579637 0,13149589 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02579637 0,13121789 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02579637 0,13094105 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02579637 0,13066539 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02579637 0,13039088 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02579637 0,13011753 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02579637 0,12984531 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02579637 0,12957424 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02579637 0,12930429 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02579637 0,12903547 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02579637 0,12876776 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02579637 0,12850116 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02579637 0,12823566 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02579637 0,12797126 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02579637 0,12770794 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02579637 0,12744571 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02579637 0,12718455 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02579637 0,12692446 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02579637 0,12666543 ! histidine catabolic process GO:0006548 6 5 0,000 0,02579637 0,12640745 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02579637 0,12615053 ! microvillus organization GO:0032528 7 5 0,000 0,02579637 0,12589464 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02579637 0,1256398 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02579637 0,12538598 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02579637 0,12513319 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02579637 0,12488141 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02579637 0,12463064 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02579637 0,12438088 ! polyol catabolic process GO:0046174 7 5 0,000 0,02579637 0,12413212 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02579637 0,12388435 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02579637 0,12363757 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02579637 0,12339177 ! muscle cell migration GO:0014812 8 5 0,000 0,02579637 0,12314694 ! mitochondrial fission GO:0000266 8 5 0,000 0,02579637 0,12290309 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02579637 0,1226602 ! mRNA transcription GO:0009299 9 5 0,000 0,02579637 0,12241826 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02579637 0,12217728 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02579637 0,12193725 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02579637 0,12169816 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02579637 0,12146 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02579637 0,12122277 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02579637 0,12098647 ! response to food GO:0032094 6 5 0,000 0,02579637 0,12075109 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02579637 0,12051662 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02579637 0,12028306 GO:0032881|regulation of polysaccharide metabolic process, ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02579637 0,12005041 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02579637 0,11981865 ! forebrain neuron development GO:0021884 13 5 0,000 0,02579637 0,11958778 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02579637 0,11935781 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02579637 0,11912871 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02579637 0,1189005 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02579637 0,11867315 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02579637 0,11844668 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02579637 0,11822107 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02579637 0,11799631 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02579637 0,11777241 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02579637 0,11754936 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02579637 0,11732715 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02579637 0,11710577 ! basic amino acid transport GO:0015802 11 5 0,000 0,02579637 0,11688524 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02579637 0,11666553 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02579637 0,11644664 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02579637 0,11622858 ! depyrimidination GO:0045008 10 5 0,000 0,02579637 0,11601133 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02579637 0,11579489 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02579637 0,11557926 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02579637 0,11536442 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02579637 0,11515039 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02579637 0,11493715 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02579637 0,11472469 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02579637 0,11451303 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02579637 0,11430214 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02579637 0,11409202 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02579637 0,11388268 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02579637 0,1136741 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02579637 0,11346629 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02579637 0,11325923 ! response to arsenic GO:0046685 10 5 0,000 0,02579637 0,11305293 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02579637 0,11284738 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02579637 0,11264258 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02579637 0,11243851 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02579637 0,11223519 ! response to cadmium ion GO:0046686 7 5 0,000 0,02579637 0,1120326 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02579637 0,11183074 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02579637 0,1116296 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02579637 0,11142919 ! decidualization GO:0046697 11 5 0,000 0,02579637 0,1112295 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02579637 0,11103052 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02579637 0,11083225 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02579637 0,11063469 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02579637 0,11043783 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02579637 0,11024167 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02579637 0,11004621 ! embryonic cleavage GO:0040016 6 5 0,000 0,02579637 0,10985143 ! peroxisome fission GO:0016559 5 5 0,000 0,02579637 0,10965735 ! histone demethylation GO:0016577 10 5 0,000 0,02579637 0,10946395 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02579637 0,10927123 ! mitotic recombination GO:0006312 9 5 0,000 0,02579637 0,10907919 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02579637 0,10888782 ! metaphase plate congression GO:0051310 7 5 0,000 0,02579637 0,10869713 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02579637 0,1085071 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02579637 0,10831773 ! enteric nervous system development GO:0048484 8 5 0,000 0,02579637 0,10812902 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02579637 0,10794097 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02579637 0,10775358 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02579637 0,10756683 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02579637 0,10738073 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02579637 0,10719527 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02579637 0,10701045 ! plasminogen activation GO:0031639 5 5 0,000 0,02579637 0,10682626 ! B cell homeostasis GO:0001782 13 5 0,000 0,02579637 0,10664271 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02579637 0,10645979 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02579637 0,1062775 ! metaphase GO:0051323 8 5 0,000 0,02579637 0,10609583 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02579637 0,10591478 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02579637 0,10573434 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02579637 0,10555452 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02579637 0,10537531 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02579637 0,10519671 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02579637 0,10501871 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02579637 0,10484132 ! response to redox state GO:0051775 5 5 0,000 0,02579637 0,10466452 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02579637 0,10448832 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02579637 0,10431271 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02579637 0,10413768 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02579637 0,10396325 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02579637 0,1037894 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02579637 0,10361613 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02579637 0,10344343 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02579637 0,10327131 ! striatum development GO:0021756 9 5 0,000 0,02579637 0,10309977 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02579637 0,10292879 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02579637 0,10275838 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02579637 0,10258853 ! glial cell migration GO:0008347 11 5 0,000 0,02579637 0,10241924 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02579637 0,10225051 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02579637 0,10208234 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02579637 0,10191471 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02579637 0,10174764 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02579637 0,10158111 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02579637 0,10141513 ! neuroprotection GO:0043526 6 5 0,000 0,02579637 0,10124969 ! neural plate development GO:0001840 8 5 0,000 0,02579637 0,10108479 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02579637 0,10092042 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02579637 0,10075659 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02579637 0,10059329 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02579637 0,10043052 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02579637 0,10026827 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02579637 0,10010655 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02579637 0,09994535 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02579637 0,09978466 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02579637 0,09962449 ! spindle assembly GO:0051225 6 5 0,000 0,02579637 0,09946484 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02579637 0,0993057 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02579637 0,09914706 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02579637 0,09898893 ! drug metabolic process GO:0017144 6 5 0,000 0,02579637 0,09883131 ! stem cell division GO:0017145 11 5 0,000 0,02579637 0,09867418 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02579637 0,09851756 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02579637 0,09836143 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02579637 0,09820579 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02579637 0,09805065 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,02604312 0,09883242 ! cellular component disassembly GO:0022411 86 48 1,000 0,02604312 0,09867678 ! activation of caspase activity GO:0006919 84 48 1,000 0,02604312 0,09852162 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,02604312 0,09836696 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02604312 0,09821278 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,02604312 0,09805908 ! regulation of action potential GO:0001508 95 49 1,000 0,02705995 0,10172849 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02705995 0,10156979 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,02705995 0,10141158 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,02705995 0,10125386 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,02705995 0,10109663 ! neuromuscular process GO:0050905 99 50 1,000 0,0280926 0,10479195 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,0280926 0,10462973 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,0280926 0,10446802 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,0280926 0,1043068 ! viral infectious cycle GO:0019058 99 51 1,000 0,0291409 0,10803238 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,0291409 0,10786618 ! chromatin remodeling GO:0006338 109 51 1,000 0,0291409 0,10770049 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,0291409 0,1075353 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 0,0291409 0,10737062 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03020466 0,11111989 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03087574 0,1134153 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03087574 0,11324241 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03087574 0,11307005 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03087574 0,11289821 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03087574 0,11272689 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03087574 0,11255609 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03087574 0,11238581 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03087574 0,11221605 ! sleep GO:0030431 13 6 0,000 0,03087574 0,11204679 ! response to oxygen radical GO:0000305 11 6 0,000 0,03087574 0,11187805 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03087574 0,11170981 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03087574 0,11154208 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03087574 0,11137485 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03087574 0,11120812 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03087574 0,11104189 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03087574 0,11087615 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03087574 0,11071091 ! forebrain regionalization GO:0021871 8 6 0,000 0,03087574 0,11054616 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03087574 0,11038191 ! male meiosis GO:0007140 7 6 0,000 0,03087574 0,11021813 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03087574 0,11005485 ! response to zinc ion GO:0010043 9 6 0,000 0,03087574 0,10989205 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03087574 0,10972972 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03087574 0,10956788 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03087574 0,10940651 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03087574 0,10924562 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03087574 0,1090852 ! malate metabolic process GO:0006108 11 6 0,000 0,03087574 0,10892525 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03087574 0,10876577 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03087574 0,10860676 ! protein refolding GO:0042026 15 6 0,000 0,03087574 0,10844821 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03087574 0,10829012 ! opsonization GO:0008228 8 6 0,000 0,03087574 0,10813249 ! mating behavior GO:0007617 7 6 0,000 0,03087574 0,10797532 ! neuron remodeling GO:0016322 15 6 0,000 0,03087574 0,10781861 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03087574 0,10766235 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03087574 0,10750655 ! equilibrioception GO:0050957 14 6 0,000 0,03087574 0,10735119 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03087574 0,10719628 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03087574 0,10704182 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03087574 0,1068878 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03087574 0,10673423 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03087574 0,10658109 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03087574 0,1064284 ! toxin metabolic process GO:0009404 11 6 0,000 0,03087574 0,10627614 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03087574 0,10612432 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03087574 0,10597293 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03087574 0,10582197 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03087574 0,10567144 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03087574 0,10552134 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03087574 0,10537166 ! protein lipoylation GO:0009249 10 6 0,000 0,03087574 0,10522241 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03087574 0,10507358 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03087574 0,10492517 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03087574 0,10477718 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03087574 0,10462961 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03087574 0,10448245 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03087574 0,10433571 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03087574 0,10418937 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03087574 0,10404345 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03087574 0,10389793 ! hyperosmotic response GO:0006972 9 6 0,000 0,03087574 0,10375282 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03087574 0,10360812 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03087574 0,10346382 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03087574 0,10331992 ! urea metabolic process GO:0019627 7 6 0,000 0,03087574 0,10317642 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03087574 0,10303332 ! neutrophil activation GO:0042119 8 6 0,000 0,03087574 0,10289061 ! regulation of appetite GO:0032098 9 6 0,000 0,03087574 0,1027483 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03087574 0,10260638 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03087574 0,10246486 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03087574 0,10232372 ! neuron apoptosis GO:0051402 9 6 0,000 0,03087574 0,10218297 ! nucleoside salvage GO:0043174 9 6 0,000 0,03087574 0,10204261 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03087574 0,10190264 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03087574 0,10176304 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03087574 0,10162383 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03087574 0,101485 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03087574 0,10134655 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03087574 0,10120848 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03087574 0,10107078 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03087574 0,10093345 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03087574 0,1007965 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03087574 0,10065992 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03087574 0,10052371 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03087574 0,10038787 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03087574 0,10025239 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03087574 0,10011728 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03087574 0,09998253 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03087574 0,09984815 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03087574 0,09971412 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03087574 0,09958046 ! response to UV-C GO:0010225 11 6 0,000 0,03087574 0,09944715 ! astrocyte development GO:0014002 15 6 0,000 0,03087574 0,0993142 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03087574 0,09918161 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03087574 0,09904936 ! interaction with symbiont GO:0051702 13 6 0,000 0,03087574 0,09891747 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03087574 0,09878593 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03087574 0,09865474 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03087574 0,0985239 ! response to copper ion GO:0046688 10 6 0,000 0,03087574 0,09839341 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03087574 0,09826326 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03087574 0,09813345 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03087574 0,09800399 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03087574 0,09787487 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03087574 0,09774608 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03087574 0,09761764 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03087574 0,09748953 ! hair follicle maturation GO:0048820 7 6 0,000 0,03087574 0,09736176 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03087574 0,09723432 ! Schwann cell development GO:0014044 15 6 0,000 0,03087574 0,09710722 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03087574 0,09698045 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03087574 0,09685401 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03087574 0,09672789 ! subpallium development GO:0021544 10 6 0,000 0,03087574 0,09660211 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03087574 0,09647665 ! histone ubiquitination GO:0016574 8 6 0,000 0,03087574 0,09635152 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03087574 0,09622671 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03087574 0,09610223 ! G2 phase GO:0051319 16 6 0,000 0,03087574 0,09597807 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03087574 0,09585422 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03087574 0,0957307 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03087574 0,09560749 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03087574 0,0954846 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03087574 0,09536203 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03087574 0,09523977 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03087574 0,09511783 ! receptor internalization GO:0031623 10 6 0,000 0,03087574 0,09499619 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03087574 0,09487487 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03087574 0,09475386 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03087574 0,09463315 ! protein deubiquitination GO:0016579 14 6 0,000 0,03087574 0,09451275 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03087574 0,09439266 ! protein destabilization GO:0031648 9 6 0,000 0,03087574 0,09427287 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03087574 0,09415339 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03087574 0,09403421 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03087574 0,09391533 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03087574 0,09379675 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03087574 0,09367846 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03087574 0,09356048 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03087574 0,0934428 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03087574 0,09332541 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03087574 0,09320831 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03087574 0,09309151 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03087574 0,092975 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03087574 0,09285878 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03087574 0,09274285 ! catecholamine transport GO:0051937 9 6 0,000 0,03087574 0,09262721 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03087574 0,09251186 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03087574 0,09239679 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03087574 0,09228202 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03087574 0,09216752 ! maternal placenta development GO:0001893 12 6 0,000 0,03087574 0,09205331 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03087574 0,09193938 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03087574 0,09182574 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03087574 0,09171237 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03087574 0,09159929 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03087574 0,09148648 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03087574 0,09137395 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03087574 0,0912617 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,03128368 0,09235402 ! regulation of translational initiation GO:0006446 82 53 1,000 0,03128368 0,09224084 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03128368 0,09212794 ! response to UV GO:0009411 104 53 1,000 0,03128368 0,09201532 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03237778 0,09511713 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03237778 0,09500114 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,03348677 0,09813542 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 1,000 0,03348677 0,09801603 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03348677 0,09789693 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,03348677 0,09777813 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,03348677 0,09765961 ! nuclear export GO:0051168 97 55 1,000 0,03348677 0,09754138 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03348677 0,09742343 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03461048 0,10057104 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,03574872 0,10375323 ! muscle fiber development GO:0048747 112 57 1,000 0,03574872 0,10362823 ! lipid modification GO:0030258 97 57 1,000 0,03574872 0,10350352 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03574872 0,10337912 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,03574872 0,10325502 ! maintenance of location GO:0051235 118 57 1,000 0,03574872 0,10313121 ! tRNA transcription GO:0009304 14 7 0,000 0,03592879 0,10352655 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03592879 0,10340272 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03592879 0,10327918 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03592879 0,10315593 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03592879 0,10303298 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03592879 0,10291032 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03592879 0,10278796 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03592879 0,10266588 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03592879 0,10254409 ! prostate gland development GO:0030850 13 7 0,000 0,03592879 0,1024226 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03592879 0,10230139 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03592879 0,10218046 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03592879 0,10205982 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03592879 0,10193947 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03592879 0,1018194 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03592879 0,10169961 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03592879 0,10158011 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03592879 0,10146088 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03592879 0,10134194 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03592879 0,10122327 ! glycolipid transport GO:0046836 10 7 0,000 0,03592879 0,10110488 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03592879 0,10098676 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03592879 0,10086893 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03592879 0,10075136 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03592879 0,10063408 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03592879 0,10051706 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03592879 0,10040031 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03592879 0,10028384 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03592879 0,10016764 ! mRNA stabilization GO:0048255 18 7 0,000 0,03592879 0,1000517 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03592879 0,09993604 ! fibril organization GO:0043206 16 7 0,000 0,03592879 0,09982064 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03592879 0,0997055 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03592879 0,09959063 ! lipoprotein transport GO:0042953 14 7 0,000 0,03592879 0,09947603 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03592879 0,09936169 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03592879 0,09924761 ! rhythmic behavior GO:0007622 15 7 0,000 0,03592879 0,0991338 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03592879 0,09902024 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03592879 0,09890695 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03592879 0,09879391 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03592879 0,09868113 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03592879 0,09856861 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03592879 0,09845634 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03592879 0,09834434 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03592879 0,09823258 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03592879 0,09812108 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03592879 0,09800983 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03592879 0,09789883 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03592879 0,09778809 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03592879 0,09767759 ! spinal cord patterning GO:0021511 13 7 0,000 0,03592879 0,09756735 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03592879 0,09745735 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03592879 0,0973476 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03592879 0,0972381 ! adrenal gland development GO:0030325 17 7 0,000 0,03592879 0,09712884 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03592879 0,09701983 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03592879 0,09691107 ! ovulation GO:0030728 9 7 0,000 0,03592879 0,09680254 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03592879 0,09669426 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03592879 0,09658622 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03592879 0,09647843 ! microtubule nucleation GO:0007020 20 7 0,000 0,03592879 0,09637087 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03592879 0,09626355 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03592879 0,09615647 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03592879 0,09604963 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03592879 0,09594303 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03592879 0,09583666 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03592879 0,09573053 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03592879 0,09562464 ! galactose metabolic process GO:0006012 13 7 0,000 0,03592879 0,09551897 ! vesicle fusion GO:0006906 17 7 0,000 0,03592879 0,09541354 ! response to dietary excess GO:0002021 8 7 0,000 0,03592879 0,09530835 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03592879 0,09520338 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03592879 0,09509865 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03592879 0,09499414 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03592879 0,09488987 ! organ growth GO:0035265 15 7 0,000 0,03592879 0,09478582 ! purine salvage GO:0043101 10 7 0,000 0,03592879 0,09468201 ! nucleoside transport GO:0015858 8 7 0,000 0,03592879 0,09457841 ! parturition GO:0007567 14 7 0,000 0,03592879 0,09447505 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03592879 0,09437191 ! rRNA modification GO:0000154 14 7 0,000 0,03592879 0,094269 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03592879 0,09416631 ! spindle checkpoint GO:0031577 15 7 0,000 0,03592879 0,09406384 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03592879 0,0939616 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03592879 0,09385958 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03592879 0,09375778 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03592879 0,0936562 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03592879 0,09355484 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03592879 0,0934537 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03592879 0,09335278 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03592879 0,09325207 ! fibrinolysis GO:0042730 10 7 0,000 0,03592879 0,09315158 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03592879 0,09305131 ! eating behavior GO:0042755 7 7 0,000 0,03592879 0,09295126 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03592879 0,09285142 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03592879 0,09275179 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03592879 0,09265238 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03592879 0,09255318 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03592879 0,09245419 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03592879 0,09235542 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03592879 0,09225685 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03592879 0,0921585 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03592879 0,09206035 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03592879 0,09196242 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03592879 0,09186469 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03592879 0,09176717 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03592879 0,09166985 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03592879 0,09157274 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03592879 0,09147584 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03592879 0,09137914 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03592879 0,09128265 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03592879 0,09118636 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03592879 0,09109027 ! transcription termination GO:0006353 13 7 0,000 0,03592879 0,09099439 ! response to tumor cell GO:0002347 13 7 0,000 0,03592879 0,09089871 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03592879 0,09080323 ! anaphase GO:0051322 17 7 0,000 0,03592879 0,09070794 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03592879 0,09061286 ! axonal fasciculation GO:0007413 18 7 0,000 0,03592879 0,09051798 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03592879 0,0904233 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03592879 0,09032881 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03592879 0,09023452 ! diuresis GO:0030146 12 7 0,000 0,03592879 0,09014043 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03592879 0,09004653 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03592879 0,08995283 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03592879 0,08985932 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03592879 0,08976601 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03592879 0,08967289 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03592879 0,08957997 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03592879 0,08948724 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03592879 0,0893947 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03592879 0,08930235 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03592879 0,08921019 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03592879 0,08911822 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03592879 0,08902644 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03592879 0,08893485 ! lymph node development GO:0048535 10 7 0,000 0,03592879 0,08884344 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03592879 0,08875223 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03592879 0,0886612 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03592879 0,08857036 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03592879 0,0884797 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03592879 0,08838923 ! adult feeding behavior GO:0008343 9 7 0,000 0,03592879 0,08829895 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03592879 0,08820885 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03592879 0,08811893 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03592879 0,0880292 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03592879 0,08793964 ! retina homeostasis GO:0001895 12 7 0,000 0,03592879 0,08785027 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03592879 0,08776109 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03592879 0,08767208 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03592879 0,08758325 ! protein prenylation GO:0018342 18 7 0,000 0,03592879 0,08749461 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03592879 0,08740614 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03592879 0,08731785 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03592879 0,08722974 ! regulation of endocytosis GO:0030100 91 58 1,000 0,03690132 0,08950057 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03690132 0,08941044 ! DNA catabolic process GO:0006308 86 59 1,000 0,03806808 0,09214467 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,03924884 0,09490725 ! camera-type eye development GO:0043010 116 60 1,000 0,03924884 0,09481197 ! glycerophospholipid biosynthetic process GO:0046474 105 61 1,000 0,04044343 0,09759968 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04095566 0,0987368 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04095566 0,09863797 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,04095566 0,09853933 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04095566 0,09844089 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04095566 0,09834264 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04095566 0,0982446 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04095566 0,09814674 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04095566 0,09804908 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04095566 0,09795162 ! meiotic prophase I GO:0007128 13 8 0,000 0,04095566 0,09785435 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04095566 0,09775727 ! oligopeptide transport GO:0006857 15 8 0,000 0,04095566 0,09766039 ! UTP metabolic process GO:0046051 8 8 0,000 0,04095566 0,09756369 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04095566 0,09746719 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04095566 0,09737088 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04095566 0,09727476 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04095566 0,09717883 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04095566 0,09708308 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04095566 0,09698753 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04095566 0,09689216 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04095566 0,09679698 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04095566 0,09670199 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04095566 0,09660719 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04095566 0,09651257 ! reflex GO:0060004 16 8 0,000 0,04095566 0,09641813 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04095566 0,09632388 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04095566 0,09622981 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04095566 0,09613593 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04095566 0,09604223 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04095566 0,09594871 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04095566 0,09585538 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04095566 0,09576223 ! pigment granule organization GO:0048753 16 8 0,000 0,04095566 0,09566925 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04095566 0,09557646 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04095566 0,09548385 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04095566 0,09539141 ! histidine metabolic process GO:0006547 16 8 0,000 0,04095566 0,09529916 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04095566 0,09520708 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04095566 0,09511518 ! glycine catabolic process GO:0006546 13 8 0,000 0,04095566 0,09502346 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04095566 0,09493192 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04095566 0,09484055 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04095566 0,09474936 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04095566 0,09465834 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04095566 0,09456749 ! melanin metabolic process GO:0006582 15 8 0,000 0,04095566 0,09447683 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04095566 0,09438633 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04095566 0,09429601 ! macrophage activation GO:0042116 12 8 0,000 0,04095566 0,09420586 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04095566 0,09411588 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04095566 0,09402608 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04095566 0,09393644 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04095566 0,09384698 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04095566 0,09375769 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04095566 0,09366856 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04095566 0,09357961 ! osteoblast development GO:0002076 16 8 0,000 0,04095566 0,09349083 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04095566 0,09340221 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04095566 0,09331376 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04095566 0,09322548 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04095566 0,09313736 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04095566 0,09304941 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04095566 0,09296163 ! response to UV-B GO:0010224 16 8 0,000 0,04095566 0,09287401 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04095566 0,09278656 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04095566 0,09269928 ! intermediate filament organization GO:0045109 12 8 0,000 0,04095566 0,09261215 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04095566 0,09252519 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04095566 0,0924384 ! cellular extravasation GO:0045123 12 8 0,000 0,04095566 0,09235176 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04095566 0,09226529 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04095566 0,09217898 ! response to antibiotic GO:0046677 11 8 0,000 0,04095566 0,09209283 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04095566 0,09200684 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04095566 0,09192102 ! DNA topological change GO:0006265 12 8 0,000 0,04095566 0,09183535 ! response to tropane GO:0014073 15 8 0,000 0,04095566 0,09174984 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04095566 0,09166449 ! melanosome transport GO:0032402 13 8 0,000 0,04095566 0,0915793 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04095566 0,09149427 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04095566 0,0914094 ! mast cell activation GO:0045576 14 8 0,000 0,04095566 0,09132468 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04095566 0,09124012 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04095566 0,09115572 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04095566 0,09107147 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04095566 0,09098738 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04095566 0,09090344 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04095566 0,09081966 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04095566 0,09073603 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04095566 0,09065256 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04095566 0,09056924 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04095566 0,09048607 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04095566 0,09040305 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04095566 0,09032019 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04095566 0,09023748 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04095566 0,09015492 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04095566 0,09007251 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04095566 0,08999026 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04095566 0,08990815 ! hormone catabolic process GO:0042447 17 8 0,000 0,04095566 0,08982619 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04095566 0,08974438 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04095566 0,08966272 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04095566 0,08958121 ! ATP catabolic process GO:0006200 11 8 0,000 0,04095566 0,08949985 ! blastocyst growth GO:0001832 19 8 0,000 0,04095566 0,08941863 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04095566 0,08933756 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04095566 0,08925664 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04095566 0,08917586 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04095566 0,08909523 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04095566 0,08901475 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04095566 0,08893441 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04095566 0,08885422 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04095566 0,08877417 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04095566 0,08869427 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04095566 0,08861451 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04095566 0,08853489 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04095566 0,08845541 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04095566 0,08837608 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04095566 0,08829689 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04095566 0,08821784 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04095566 0,08813894 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04095566 0,08806017 ! ear development GO:0043583 103 62 1,000 0,04165166 0,08947668 ! gonad development GO:0008406 98 62 1,000 0,04165166 0,08939686 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,04287336 0,09193699 ! detection of external stimulus GO:0009581 91 63 1,000 0,04287336 0,09185512 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,04410836 0,09441701 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,04410836 0,09433309 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,04410836 0,09424931 GO:0048609|reproductive process in a multicellular organism, ! axon extension GO:0048675 15 9 0,000 0,04595649 0,0981112 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04595649 0,09802422 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04595649 0,0979374 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04595649 0,09785073 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04595649 0,09776421 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04595649 0,09767785 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04595649 0,09759164 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04595649 0,09750558 ! phosphate transport GO:0006817 19 9 0,000 0,04595649 0,09741967 ! reproductive behavior GO:0019098 19 9 0,000 0,04595649 0,09733391 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04595649 0,09724831 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04595649 0,09716285 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04595649 0,09707755 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04595649 0,09699239 ! GTP metabolic process GO:0046039 9 9 0,000 0,04595649 0,09690738 ! RNA methylation GO:0001510 15 9 0,000 0,04595649 0,09682253 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04595649 0,09673782 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04595649 0,09665326 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04595649 0,09656884 ! artery development GO:0060840 24 9 0,000 0,04595649 0,09648458 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04595649 0,09640046 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04595649 0,09631648 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04595649 0,09623266 ! chemosensory behavior GO:0007635 20 9 0,000 0,04595649 0,09614898 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04595649 0,09606544 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04595649 0,09598205 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04595649 0,09589881 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04595649 0,09581571 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04595649 0,09573275 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04595649 0,09564993 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04595649 0,09556726 ! protein targeting to ER GO:0045047 22 9 0,000 0,04595649 0,09548474 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04595649 0,09540235 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04595649 0,09532011 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04595649 0,09523801 ! endosome organization GO:0007032 17 9 0,000 0,04595649 0,09515605 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04595649 0,09507423 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04595649 0,09499255 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04595649 0,09491101 ! mannose metabolic process GO:0006013 13 9 0,000 0,04595649 0,09482961 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04595649 0,09474835 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04595649 0,09466723 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04595649 0,09458625 ! receptor clustering GO:0043113 18 9 0,000 0,04595649 0,09450541 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04595649 0,0944247 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04595649 0,09434413 ! ruffle organization GO:0031529 15 9 0,000 0,04595649 0,0942637 ! retinol metabolic process GO:0042572 18 9 0,000 0,04595649 0,09418341 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04595649 0,09410325 ! behavioral fear response GO:0001662 22 9 0,000 0,04595649 0,09402323 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04595649 0,09394335 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04595649 0,0938636 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04595649 0,09378399 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04595649 0,09370451 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04595649 0,09362517 ! segment specification GO:0007379 13 9 0,000 0,04595649 0,09354596 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04595649 0,09346688 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04595649 0,09338794 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04595649 0,09330913 ! response to amine stimulus GO:0014075 13 9 0,000 0,04595649 0,09323046 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04595649 0,09315192 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04595649 0,09307351 ! erythrocyte development GO:0048821 15 9 0,000 0,04595649 0,09299523 ! gas homeostasis GO:0033483 16 9 0,000 0,04595649 0,09291708 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04595649 0,09283906 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04595649 0,09276118 ! renal water homeostasis GO:0003091 14 9 0,000 0,04595649 0,09268342 ! postreplication repair GO:0006301 22 9 0,000 0,04595649 0,0926058 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04595649 0,0925283 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04595649 0,09245094 ! icosanoid secretion GO:0032309 15 9 0,000 0,04595649 0,0923737 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04595649 0,0922966 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04595649 0,09221962 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04595649 0,09214277 ! regulation of cell division GO:0051302 15 9 0,000 0,04595649 0,09206605 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04595649 0,09198945 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04595649 0,09191299 ! sterol catabolic process GO:0016127 11 9 0,000 0,04595649 0,09183665 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04595649 0,09176044 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04595649 0,09168435 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04595649 0,09160839 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04595649 0,09153255 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04595649 0,09145684 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04595649 0,09138126 ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04595649 0,0913058 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04595649 0,09123047 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04595649 0,09115526 ! purine base metabolic process GO:0006144 21 9 0,000 0,04595649 0,09108017 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04595649 0,09100521 ! pigment granule transport GO:0051904 17 9 0,000 0,04595649 0,09093037 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04595649 0,09085565 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04595649 0,09078105 ! mitochondrion localization GO:0051646 15 9 0,000 0,04595649 0,09070658 ! lung development GO:0030324 144 67 1,000 0,0478915 0,09444833 ! hexose catabolic process GO:0019320 104 67 1,000 0,0478915 0,09437097 ! adaptive immune response GO:0002250 119 67 1,000 0,0478915 0,09429375 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,04917803 0,09674763 ! glycerolipid biosynthetic process GO:0045017 118 69 1,000 0,05047703 0,09922201 ! antigen processing and presentation GO:0019882 104 69 1,000 0,05047703 0,09914101 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,05093141 0,09995186 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05093141 0,0998704 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05093141 0,09978907 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05093141 0,09970787 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05093141 0,09962681 ! synapsis GO:0007129 13 10 0,000 0,05093141 0,09954588 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05093141 0,09946508 ! N-glycan processing GO:0006491 20 10 0,000 0,05093141 0,09938441 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05093141 0,09930387 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05093141 0,09922346 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05093141 0,09914319 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05093141 0,09906304 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05093141 0,09898302 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05093141 0,09890313 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05093141 0,09882337 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05093141 0,09874374 ! androgen metabolic process GO:0008209 17 10 0,000 0,05093141 0,09866423 ! phospholipid efflux GO:0033700 16 10 0,000 0,05093141 0,09858486 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05093141 0,09850561 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05093141 0,09842649 ! lung alveolus development GO:0048286 26 10 0,000 0,05093141 0,09834749 ! pathogenesis GO:0009405 13 10 0,000 0,05093141 0,09826863 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05093141 0,09818989 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05093141 0,09811127 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05093141 0,09803278 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05093141 0,09795442 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05093141 0,09787618 ! endoderm development GO:0007492 16 10 0,000 0,05093141 0,09779807 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05093141 0,09772008 ! arginine catabolic process GO:0006527 13 10 0,000 0,05093141 0,09764221 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05093141 0,09756447 ! proline metabolic process GO:0006560 13 10 0,000 0,05093141 0,09748686 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05093141 0,09740936 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05093141 0,09733199 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05093141 0,09725474 ! V(D)J recombination GO:0033151 28 10 0,000 0,05093141 0,09717762 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05093141 0,09710062 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05093141 0,09702373 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05093141 0,09694698 ! B cell proliferation GO:0042100 18 10 0,000 0,05093141 0,09687034 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05093141 0,09679382 ! multicellular organism growth GO:0035264 18 10 0,000 0,05093141 0,09671742 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05093141 0,09664115 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05093141 0,09656499 ! epithelial cell development GO:0002064 20 10 0,000 0,05093141 0,09648896 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05093141 0,09641304 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05093141 0,09633725 ! macroautophagy GO:0016236 17 10 0,000 0,05093141 0,09626157 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05093141 0,09618601 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05093141 0,09611057 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05093141 0,09603525 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05093141 0,09596004 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05093141 0,09588496 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05093141 0,09580999 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05093141 0,09573514 ! brain morphogenesis GO:0048854 23 10 0,000 0,05093141 0,0956604 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05093141 0,09558579 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05093141 0,09551128 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05093141 0,0954369 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05093141 0,09536263 ! response to dsRNA GO:0043331 20 10 0,000 0,05093141 0,09528847 ! DNA ligation GO:0006266 19 10 0,000 0,05093141 0,09521443 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05093141 0,09514051 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05093141 0,0950667 ! melanosome localization GO:0032400 16 10 0,000 0,05093141 0,09499301 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05093141 0,09491942 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05093141 0,09484596 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05093141 0,0947726 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05093141 0,09469936 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05093141 0,09462624 ! mRNA cleavage GO:0006379 17 10 0,000 0,05093141 0,09455322 ! protein sumoylation GO:0016925 15 10 0,000 0,05093141 0,09448032 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05093141 0,09440753 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05093141 0,09433486 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05093141 0,09426229 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05093141 0,09418984 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05093141 0,09411749 ! salivary gland development GO:0007431 27 10 0,000 0,05093141 0,09404526 ! prophase GO:0051324 15 10 0,000 0,05093141 0,09397314 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05093141 0,09390113 ! apical protein localization GO:0045176 15 10 0,000 0,05093141 0,09382923 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05093141 0,09375744 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05093141 0,09368576 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05093141 0,09361419 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05093141 0,09354273 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05093141 0,09347138 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05093141 0,09340013 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05093141 0,093329 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05093141 0,09325797 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05093141 0,09318705 ! detection of calcium ion GO:0005513 23 10 0,000 0,05093141 0,09311624 ! oocyte development GO:0048599 17 10 0,000 0,05093141 0,09304554 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05093141 0,09297494 ! blastocyst formation GO:0001825 17 10 0,000 0,05093141 0,09290446 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05093141 0,09283407 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05093141 0,0927638 ! activation of innate immune response GO:0002218 12 10 0,000 0,05093141 0,09269363 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05093141 0,09262357 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05093141 0,09255361 ! response to nicotine GO:0035094 20 10 0,000 0,05093141 0,09248376 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05093141 0,09241401 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05093141 0,09234437 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05093141 0,09227483 ! localization within membrane GO:0051668 20 10 0,000 0,05093141 0,0922054 ! respiratory tube development GO:0030323 150 70 1,000 0,05178833 0,09368626 ! reproductive structure development GO:0048608 113 71 1,000 0,05311177 0,09600821 ! B cell activation GO:0042113 160 71 1,000 0,05311177 0,09593613 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0544472 0,09827453 ! respiratory system development GO:0060541 153 72 1,000 0,0544472 0,09820087 ! regulation of blood pressure GO:0008217 125 73 1,000 0,05579444 0,10055538 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05588055 0,10063519 ! respiratory burst GO:0045730 17 11 0,000 0,05588055 0,10055992 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05588055 0,10048476 ! neuron fate specification GO:0048665 17 11 0,000 0,05588055 0,10040972 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05588055 0,10033478 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05588055 0,10025996 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,05588055 0,10018525 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,05588055 0,10011065 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05588055 0,10003617 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05588055 0,09996179 ! response to pain GO:0048265 24 11 0,000 0,05588055 0,09988752 ! T cell proliferation GO:0042098 26 11 0,000 0,05588055 0,09981337 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,05588055 0,09973932 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,05588055 0,09966539 ! bone resorption GO:0045453 16 11 0,000 0,05588055 0,09959156 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05588055 0,09951785 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05588055 0,09944424 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05588055 0,09937074 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05588055 0,09929735 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05588055 0,09922407 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05588055 0,09915089 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05588055 0,09907783 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05588055 0,09900487 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05588055 0,09893202 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05588055 0,09885927 ! lipid digestion GO:0044241 18 11 0,000 0,05588055 0,09878663 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05588055 0,0987141 ! UV protection GO:0009650 19 11 0,000 0,05588055 0,09864168 ! adult heart development GO:0007512 14 11 0,000 0,05588055 0,09856936 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,05588055 0,09849715 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05588055 0,09842504 ! temperature homeostasis GO:0001659 17 11 0,000 0,05588055 0,09835304 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05588055 0,09828115 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05588055 0,09820936 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05588055 0,09813767 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05588055 0,09806609 ! regulation of organ growth GO:0046620 13 11 0,000 0,05588055 0,09799461 ! pigment granule localization GO:0051875 20 11 0,000 0,05588055 0,09792324 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05588055 0,09785197 ! vasoconstriction GO:0042310 18 11 0,000 0,05588055 0,09778081 ! embryonic axis specification GO:0000578 18 11 0,000 0,05588055 0,09770974 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05588055 0,09763879 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05588055 0,09756793 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05588055 0,09749718 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05588055 0,09742653 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05588055 0,09735598 ! zymogen activation GO:0031638 15 11 0,000 0,05588055 0,09728553 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05588055 0,09721519 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05588055 0,09714495 ! nucleosome positioning GO:0016584 15 11 0,000 0,05588055 0,09707481 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05588055 0,09700477 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05588055 0,09693483 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05588055 0,09686499 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05588055 0,09679525 ! acid secretion GO:0046717 18 11 0,000 0,05588055 0,09672562 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05588055 0,09665608 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05588055 0,09658664 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05588055 0,09651731 ! oocyte differentiation GO:0009994 18 11 0,000 0,05588055 0,09644807 ! thymus development GO:0048538 27 11 0,000 0,05588055 0,09637893 ! cholesterol efflux GO:0033344 19 11 0,000 0,05588055 0,09630989 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05588055 0,09624095 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05588055 0,09617211 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05588055 0,09610337 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05588055 0,09603472 ! embryonic gut development GO:0048566 15 11 0,000 0,05588055 0,09596617 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05588055 0,09589772 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05588055 0,09582937 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05588055 0,09576112 ! defense response to fungus GO:0050832 13 11 0,000 0,05588055 0,09569296 ! developmental induction GO:0031128 19 11 0,000 0,05588055 0,0956249 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05588055 0,09555694 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05588055 0,09548907 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05588055 0,0954213 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05588055 0,09535362 ! meiosis GO:0007126 121 74 1,000 0,05715335 0,09745639 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,05715335 0,09738737 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,05715335 0,09731845 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,05852377 0,09958147 ! meiotic cell cycle GO:0051321 122 75 1,000 0,05852377 0,09951109 ! rhythmic process GO:0048511 128 75 1,000 0,05852377 0,09944082 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,05852377 0,09937064 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,05990554 0,10164509 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,05990554 0,10157346 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06080405 0,10302432 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06080405 0,10295182 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06080405 0,10287942 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,06080405 0,10280712 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06080405 0,10273493 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06080405 0,10266283 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06080405 0,10259084 ! protein complex disassembly GO:0043241 27 12 0,000 0,06080405 0,10251895 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06080405 0,10244716 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06080405 0,10237546 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06080405 0,10230387 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06080405 0,10223238 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06080405 0,10216099 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06080405 0,1020897 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06080405 0,10201851 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06080405 0,10194741 ! drug transport GO:0015893 16 12 0,000 0,06080405 0,10187642 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06080405 0,10180552 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06080405 0,10173473 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06080405 0,10166403 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06080405 0,10159343 ! focal adhesion formation GO:0048041 35 12 0,000 0,06080405 0,10152293 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06080405 0,10145252 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06080405 0,10138222 ! forebrain cell migration GO:0021885 21 12 0,000 0,06080405 0,10131201 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06080405 0,1012419 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06080405 0,10117188 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06080405 0,10110196 ! fear response GO:0042596 26 12 0,000 0,06080405 0,10103214 ! monoamine transport GO:0015844 18 12 0,000 0,06080405 0,10096241 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06080405 0,10089279 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06080405 0,10082325 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06080405 0,10075381 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06080405 0,10068447 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06080405 0,10061523 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06080405 0,10054607 ! protein homotetramerization GO:0051289 21 12 0,000 0,06080405 0,10047702 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06080405 0,10040806 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06080405 0,10033919 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06080405 0,10027042 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06080405 0,10020174 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06080405 0,10013315 ! fucose catabolic process GO:0019317 22 12 0,000 0,06080405 0,10006466 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,06080405 0,09999627 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06080405 0,09992796 ! gland morphogenesis GO:0022612 29 12 0,000 0,06080405 0,09985975 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06080405 0,09979164 ! T cell homeostasis GO:0043029 25 12 0,000 0,06080405 0,09972361 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06080405 0,09965568 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06080405 0,09958784 ! spleen development GO:0048536 22 12 0,000 0,06080405 0,09952009 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06080405 0,09945244 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06080405 0,09938488 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06080405 0,09931741 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06080405 0,09925003 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06080405 0,09918274 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06080405 0,09911554 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06080405 0,09904844 ! response to cold GO:0009409 17 12 0,000 0,06080405 0,09898142 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06080405 0,0989145 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06080405 0,09884766 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,06129851 0,09958422 ! blood coagulation GO:0007596 146 78 1,000 0,06270253 0,10179642 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,06270253 0,10172778 ! protein oligomerization GO:0051259 139 78 1,000 0,06270253 0,10165923 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06570203 0,10645056 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06570203 0,10637893 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06570203 0,10630739 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06570203 0,10623594 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06570203 0,1061646 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06570203 0,10609335 ! lipid localization GO:0010876 28 13 0,000 0,06570203 0,10602219 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06570203 0,10595113 ! organelle fusion GO:0048284 32 13 0,000 0,06570203 0,10588016 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06570203 0,10580929 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06570203 0,10573852 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06570203 0,10566784 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06570203 0,10559725 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06570203 0,10552676 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06570203 0,10545636 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06570203 0,10538606 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06570203 0,10531585 ! methionine metabolic process GO:0006555 27 13 0,000 0,06570203 0,10524573 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06570203 0,10517571 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06570203 0,10510577 ! Golgi organization GO:0007030 24 13 0,000 0,06570203 0,10503594 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06570203 0,10496619 ! response to X-ray GO:0010165 25 13 0,000 0,06570203 0,10489654 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06570203 0,10482698 ! exocrine system development GO:0035272 32 13 0,000 0,06570203 0,10475751 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06570203 0,10468814 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06570203 0,10461885 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06570203 0,10454966 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06570203 0,10448056 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06570203 0,10441155 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06570203 0,10434263 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06570203 0,1042738 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06570203 0,10420507 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06570203 0,10413642 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06570203 0,10406786 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06570203 0,1039994 ! ribosome assembly GO:0042255 17 13 0,000 0,06570203 0,10393102 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,06570203 0,10386274 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06570203 0,10379454 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06570203 0,10372643 ! chromatin silencing GO:0006342 26 13 0,000 0,06570203 0,10365842 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06570203 0,10359049 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06570203 0,10352265 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06570203 0,1034549 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06570203 0,10338724 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06570203 0,10331966 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06570203 0,10325218 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06570203 0,10318478 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06570203 0,10311747 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06570203 0,10305025 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06570203 0,10298312 ! embryonic placenta development GO:0001892 23 13 0,000 0,06570203 0,10291607 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06570203 0,10284911 ! insulin secretion GO:0030073 23 13 0,000 0,06570203 0,10278224 ! actin filament polymerization GO:0030041 24 13 0,000 0,06570203 0,10271545 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06570203 0,10264876 ! acrosome reaction GO:0007340 18 13 0,000 0,06570203 0,10258214 ! T cell activation GO:0042110 168 81 1,000 0,06697936 0,10450865 ! response to hypoxia GO:0001666 171 81 1,000 0,06697936 0,10444092 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,06697936 0,10437327 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,06842606 0,10655864 ! response to drug GO:0042493 143 82 1,000 0,06842606 0,10648972 ! response to oxygen levels GO:0070482 176 83 1,000 0,06988307 0,10868691 ! rRNA transcription GO:0009303 25 14 0,000 0,07057463 0,10969158 ! lactation GO:0007595 26 14 0,000 0,07057463 0,10962076 ! reproductive cellular process GO:0048610 20 14 0,000 0,07057463 0,10955004 ! tRNA modification GO:0006400 20 14 0,000 0,07057463 0,10947941 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07057463 0,10940887 ! regulation of S phase GO:0033261 23 14 0,000 0,07057463 0,10933842 ! water transport GO:0006833 21 14 0,000 0,07057463 0,10926806 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07057463 0,10919779 ! non-recombinational repair GO:0000726 25 14 0,000 0,07057463 0,10912761 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07057463 0,10905752 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07057463 0,10898752 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07057463 0,10891762 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07057463 0,1088478 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07057463 0,10877807 ! palate development GO:0060021 31 14 0,000 0,07057463 0,10870843 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,07057463 0,10863888 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07057463 0,10856941 ! arginine metabolic process GO:0006525 17 14 0,000 0,07057463 0,10850004 ! regulation of heart rate GO:0002027 24 14 0,000 0,07057463 0,10843076 ! organic alcohol transport GO:0015850 29 14 0,000 0,07057463 0,10836156 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07057463 0,10829245 ! embryo implantation GO:0007566 30 14 0,000 0,07057463 0,10822343 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07057463 0,1081545 ! L-amino acid transport GO:0015807 30 14 0,000 0,07057463 0,10808565 ! bone mineralization GO:0030282 17 14 0,000 0,07057463 0,1080169 ! stem cell development GO:0048864 43 14 0,000 0,07057463 0,10794823 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07057463 0,10787965 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07057463 0,10781115 ! cerebellum development GO:0021549 21 14 0,000 0,07057463 0,10774274 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07057463 0,10767442 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07057463 0,10760619 ! response to gamma radiation GO:0010332 28 14 0,000 0,07057463 0,10753804 ! cofactor transport GO:0051181 26 14 0,000 0,07057463 0,10746998 ! NADP metabolic process GO:0006739 24 14 0,000 0,07057463 0,107402 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07057463 0,10733411 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07057463 0,10726631 ! intestinal absorption GO:0050892 25 14 0,000 0,07057463 0,10719859 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07057463 0,10713095 ! oxygen transport GO:0015671 21 14 0,000 0,07057463 0,10706341 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07057463 0,10699594 ! male genitalia development GO:0030539 24 14 0,000 0,07057463 0,10692857 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07057463 0,10686127 ! regulation of axon extension GO:0030516 37 14 0,000 0,07057463 0,10679406 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07057463 0,10672694 ! hemostasis GO:0007599 158 84 1,000 0,07135023 0,10783207 ! negative regulation of transport GO:0051051 153 84 1,000 0,07135023 0,10776438 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,0728274 0,10992643 ! oxidative phosphorylation GO:0006119 133 86 1,000 0,07431445 0,11210067 ! alcohol catabolic process GO:0046164 130 86 1,000 0,07431445 0,11203043 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07542198 0,11362886 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07542198 0,11355775 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,07542198 0,11348673 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07542198 0,1134158 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07542198 0,11334496 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07542198 0,11327421 ! copper ion transport GO:0006825 20 15 0,000 0,07542198 0,11320355 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07542198 0,11313297 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07542198 0,11306248 ! sulfate transport GO:0008272 23 15 0,000 0,07542198 0,11299208 ! response to cAMP GO:0051591 22 15 0,000 0,07542198 0,11292177 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07542198 0,11285155 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07542198 0,11278141 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07542198 0,11271136 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07542198 0,11264139 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07542198 0,11257152 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07542198 0,11250173 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07542198 0,11243202 ! pituitary gland development GO:0021983 29 15 0,000 0,07542198 0,11236241 ! vesicle coating GO:0006901 33 15 0,000 0,07542198 0,11229288 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07542198 0,11222343 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07542198 0,11215407 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07542198 0,1120848 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07542198 0,11201561 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07542198 0,11194651 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07542198 0,11187749 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07542198 0,11180856 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07542198 0,11173971 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07542198 0,11167095 ! histone deacetylation GO:0016575 20 15 0,000 0,07542198 0,11160227 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07542198 0,11153367 ! tissue regeneration GO:0042246 26 15 0,000 0,07542198 0,11146516 ! water homeostasis GO:0030104 27 15 0,000 0,07542198 0,11139674 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07542198 0,1113284 ! muscle maintenance GO:0046716 26 15 0,000 0,07542198 0,11126014 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07542198 0,11119197 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07542198 0,11112387 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07542198 0,11105587 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07542198 0,11098794 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07542198 0,1109201 ! cell killing GO:0001906 29 15 0,000 0,07542198 0,11085234 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07542198 0,11078467 ! detection of bacterium GO:0016045 18 15 0,000 0,07542198 0,11071708 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07542198 0,11064957 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07542198 0,11058214 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07542198 0,11051479 ! peptide hormone processing GO:0016486 23 15 0,000 0,07542198 0,11044753 ! regulation of protein transport GO:0051223 154 87 1,000 0,07581123 0,11095001 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 1,000 0,07731759 0,11308579 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,07883341 0,11523279 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,07883341 0,11516283 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08024421 0,11715265 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08024421 0,11708161 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08024421 0,11701065 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08024421 0,11693978 ! bone remodeling GO:0046849 27 16 0,000 0,08024421 0,11686899 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08024421 0,11679829 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08024421 0,11672767 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08024421 0,11665714 ! startle response GO:0001964 28 16 0,000 0,08024421 0,1165867 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08024421 0,11651634 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08024421 0,11644606 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08024421 0,11637587 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08024421 0,11630577 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08024421 0,11623574 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08024421 0,11616581 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08024421 0,11609595 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08024421 0,11602618 ! response to osmotic stress GO:0006970 25 16 0,000 0,08024421 0,1159565 ! lysosomal transport GO:0007041 26 16 0,000 0,08024421 0,1158869 ! fructose metabolic process GO:0006000 25 16 0,000 0,08024421 0,11581738 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08024421 0,11574794 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,08024421 0,11567859 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08024421 0,11560932 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08024421 0,11554014 ! axon cargo transport GO:0008088 43 16 0,000 0,08024421 0,11547104 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08024421 0,11540202 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08024421 0,11533308 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08024421 0,11526422 ! DNA replication initiation GO:0006270 27 16 0,000 0,08024421 0,11519545 ! neuron recognition GO:0008038 35 16 0,000 0,08024421 0,11512676 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08024421 0,11505815 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08024421 0,11498962 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08024421 0,11492117 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08024421 0,11485281 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08024421 0,11478453 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08024421 0,11471632 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08024421 0,1146482 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08024421 0,11458016 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08024421 0,1145122 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08024421 0,11444432 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08024421 0,11437652 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08024421 0,1143088 ! defense response to virus GO:0051607 37 16 0,000 0,08024421 0,11424117 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,08035854 0,11433627 ! sex differentiation GO:0007548 145 90 1,000 0,08035854 0,1142687 ! regulation of defense response GO:0031347 149 92 1,000 0,08343618 0,11857498 ! phospholipid biosynthetic process GO:0008654 167 92 1,000 0,08343618 0,11850499 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08504145 0,1207137 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08504145 0,12064253 ! metencephalon development GO:0022037 30 17 0,000 0,08504145 0,12057144 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08504145 0,12050043 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,08504145 0,1204295 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08504145 0,12035866 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08504145 0,1202879 ! signal complex assembly GO:0007172 41 17 0,000 0,08504145 0,12021723 ! endothelial cell migration GO:0043542 28 17 0,000 0,08504145 0,12014664 ! inositol metabolic process GO:0006020 28 17 0,000 0,08504145 0,12007613 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08504145 0,1200057 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08504145 0,11993536 ! glial cell development GO:0021782 27 17 0,000 0,08504145 0,1198651 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08504145 0,11979492 ! adult walking behavior GO:0007628 33 17 0,000 0,08504145 0,11972482 ! heart looping GO:0001947 30 17 0,000 0,08504145 0,11965481 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08504145 0,11958488 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08504145 0,11951503 ! myoblast differentiation GO:0045445 45 17 0,000 0,08504145 0,11944526 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08504145 0,11937557 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,08504145 0,11930596 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,08504145 0,11923644 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08504145 0,11916699 ! glycine metabolic process GO:0006544 28 17 0,000 0,08504145 0,11909763 ! NAD metabolic process GO:0019674 29 17 0,000 0,08504145 0,11902835 ! membrane budding GO:0006900 37 17 0,000 0,08504145 0,11895914 ! DNA integration GO:0015074 29 17 0,000 0,08504145 0,11889002 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,08504145 0,11882098 ! regulation of protein binding GO:0043393 33 17 0,000 0,08504145 0,11875202 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08504145 0,11868314 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08504145 0,11861433 ! genitalia development GO:0048806 30 17 0,000 0,08504145 0,11854561 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08504145 0,11847697 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08504145 0,11840841 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,08504145 0,11833992 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,08504145 0,11827152 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08504145 0,11820319 ! steroid catabolic process GO:0006706 31 17 0,000 0,08504145 0,11813495 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08504145 0,11806678 ! gas transport GO:0015669 25 17 0,000 0,08504145 0,11799869 ! organic cation transport GO:0015695 31 17 0,000 0,08504145 0,11793068 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08504145 0,11786275 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,08504145 0,11779489 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08504145 0,11772711 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,08504145 0,11765942 ! transcription initiation GO:0006352 153 94 1,000 0,08654944 0,11967699 ! regulation of T cell activation GO:0050863 158 94 1,000 0,08654944 0,11960825 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,0881191 0,12170755 ! forebrain development GO:0030900 188 95 1,000 0,0881191 0,12163772 ! detection of stimulus GO:0051606 151 96 1,000 0,08969727 0,1237452 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,08981382 0,12383499 ! neuron maturation GO:0042551 42 18 0,000 0,08981382 0,12376407 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,08981382 0,12369322 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,08981382 0,12362246 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,08981382 0,12355178 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,08981382 0,12348118 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,08981382 0,12341066 ! memory GO:0007613 31 18 0,000 0,08981382 0,12334022 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,08981382 0,12326986 ! patterning of blood vessels GO:0001569 39 18 0,000 0,08981382 0,12319958 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,08981382 0,12312938 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,08981382 0,12305926 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,08981382 0,12298922 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,08981382 0,12291926 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08981382 0,12284938 ! response to retinoic acid GO:0032526 26 18 0,000 0,08981382 0,12277958 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,08981382 0,12270986 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,08981382 0,12264022 ! response to fungus GO:0009620 21 18 0,000 0,08981382 0,12257065 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,08981382 0,12250117 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,08981382 0,12243176 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,08981382 0,12236244 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,08981382 0,12229319 ! vitamin transport GO:0051180 27 18 0,000 0,08981382 0,12222402 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,08981382 0,12215492 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,08981382 0,12208591 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,08981382 0,12201697 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,08981382 0,12194812 ! protein ubiquitination GO:0016567 217 97 1,000 0,09128381 0,12387414 ! regulation of protein localization GO:0032880 176 97 1,000 0,09128381 0,12380431 ! interphase GO:0051325 213 98 1,000 0,0928786 0,12589629 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,09448152 0,12799692 ! protein secretion GO:0009306 39 19 0,000 0,09456146 0,12803314 ! positive regulation of translation GO:0045727 30 19 0,000 0,09456146 0,12796113 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09456146 0,1278892 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09456146 0,12781735 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09456146 0,12774558 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09456146 0,1276739 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09456146 0,12760229 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09456146 0,12753076 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09456146 0,12745932 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,09456146 0,12738795 ! pigmentation during development GO:0048066 41 19 0,000 0,09456146 0,12731667 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,09456146 0,12724546 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,09456146 0,12717433 ! heme metabolic process GO:0042168 36 19 0,000 0,09456146 0,12710329 ! actin filament bundle formation GO:0051017 42 19 0,000 0,09456146 0,12703232 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09456146 0,12696143 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09456146 0,12689062 ! peptide cross-linking GO:0018149 37 19 0,000 0,09456146 0,12681989 ! heart process GO:0003015 30 19 0,000 0,09456146 0,12674924 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09456146 0,12667867 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,09456146 0,12660817 ! cellular pigmentation GO:0033059 36 19 0,000 0,09456146 0,12653775 ! G1 phase GO:0051318 40 19 0,000 0,09456146 0,12646742 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09456146 0,12639716 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09456146 0,12632698 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09456146 0,12625687 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09456146 0,12618685 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09456146 0,1261169 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09456146 0,12604703 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09456146 0,12597723 ! cilium assembly GO:0042384 37 19 0,000 0,09456146 0,12590752 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09456146 0,12583788 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0992845 0,13205003 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0992845 0,13197707 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0992845 0,1319042 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0992845 0,1318314 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,0992845 0,13175869 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0992845 0,13168605 ! response to vitamin GO:0033273 31 20 0,000 0,0992845 0,1316135 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0992845 0,13154102 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0992845 0,13146863 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0992845 0,13139632 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0992845 0,13132408 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0992845 0,13125192 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0992845 0,13117985 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0992845 0,13110785 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0992845 0,13103593 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0992845 0,13096409 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0992845 0,13089233 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0992845 0,13082065 ! body fluid secretion GO:0007589 31 20 0,000 0,0992845 0,13074904 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0992845 0,13067752 ! peptide secretion GO:0002790 35 20 0,000 0,0992845 0,13060607 ! stem cell differentiation GO:0048863 53 20 0,000 0,0992845 0,1305347 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0992845 0,13046341 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0992845 0,13039219 ! sensory perception of pain GO:0019233 30 20 0,000 0,0992845 0,13032106 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0992845 0,13025 ! diencephalon development GO:0021536 34 20 0,000 0,0992845 0,13017902 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0992845 0,13010812 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0992845 0,13003729 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0992845 0,12996654 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0992845 0,12989587 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0992845 0,12982527 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0992845 0,12975475 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0992845 0,12968431 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0992845 0,12961395 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0992845 0,12954366 ! regulation of glucose import GO:0046324 29 20 0,000 0,0992845 0,12947344 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,0992845 0,1294033 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0992845 0,12933324 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0992845 0,12926326 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0992845 0,12919335 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0992845 0,12912351 ! regulation of cell killing GO:0031341 42 21 0,000 0,10398305 0,13516111 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10398305 0,13508813 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10398305 0,13501523 ! hormone secretion GO:0046879 38 21 0,000 0,10398305 0,1349424 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10398305 0,13486966 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10398305 0,13479699 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10398305 0,1347244 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10398305 0,13465189 ! axis specification GO:0009798 38 21 0,000 0,10398305 0,13457946 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10398305 0,13450711 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10398305 0,13443483 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10398305 0,13436263 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,10398305 0,13429051 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,10398305 0,13421846 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,10398305 0,1341465 ! cytolysis GO:0019835 24 21 0,000 0,10398305 0,13407461 ! vasodilation GO:0042311 39 21 0,000 0,10398305 0,13400279 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10398305 0,13393106 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,10398305 0,1338594 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,10398305 0,13378782 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10398305 0,13371631 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10398305 0,13364488 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10398305 0,13357353 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10398305 0,13350225 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,10398305 0,13343105 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10398305 0,13335992 ! collagen catabolic process GO:0030574 28 21 0,000 0,10398305 0,13328887 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10398305 0,1332179 ! gut development GO:0048565 39 21 0,000 0,10398305 0,133147 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10865725 0,13905816 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10865725 0,13898423 ! microtubule-based transport GO:0010970 54 22 0,000 0,10865725 0,13891038 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,10865725 0,13883661 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10865725 0,13876292 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10865725 0,1386893 ! regeneration GO:0031099 41 22 0,000 0,10865725 0,13861577 ! keratinization GO:0031424 28 22 0,000 0,10865725 0,13854231 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10865725 0,13846893 ! sensory perception of taste GO:0050909 28 22 0,000 0,10865725 0,13839563 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,10865725 0,1383224 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10865725 0,13824925 ! vacuolar transport GO:0007034 36 22 0,000 0,10865725 0,13817618 ! lysosome organization GO:0007040 41 22 0,000 0,10865725 0,13810319 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10865725 0,13803027 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10865725 0,13795743 ! fucose metabolic process GO:0006004 39 22 0,000 0,10865725 0,13788467 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10865725 0,13781199 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10865725 0,13773938 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10865725 0,13766684 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,10865725 0,13759439 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10865725 0,13752201 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10865725 0,1374497 ! sarcomere organization GO:0045214 30 22 0,000 0,10865725 0,13737748 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,10865725 0,13730532 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10865725 0,13723325 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10865725 0,13716125 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,10865725 0,13708932 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11330722 0,14288111 ! gluconeogenesis GO:0006094 33 23 0,000 0,11330722 0,14280627 ! viral genome replication GO:0019079 41 23 0,000 0,11330722 0,1427315 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11330722 0,14265681 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11330722 0,1425822 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11330722 0,14250767 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11330722 0,14243321 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11330722 0,14235883 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11330722 0,14228453 ! visual behavior GO:0007632 42 23 0,000 0,11330722 0,14221031 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,11330722 0,14213616 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,11330722 0,1420621 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11330722 0,14198811 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11330722 0,14191419 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11330722 0,14184036 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11330722 0,1417666 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11330722 0,14169291 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11330722 0,14161931 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,11330722 0,14154578 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11330722 0,14147232 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11330722 0,14139894 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11330722 0,14132564 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11330722 0,14125242 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11330722 0,14117927 ! fatty acid transport GO:0015908 44 23 0,000 0,11330722 0,14110619 ! platelet activation GO:0030168 37 23 0,000 0,11330722 0,14103319 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11330722 0,14096027 ! hormone transport GO:0009914 40 23 0,000 0,11330722 0,14088742 ! cell-cell recognition GO:0009988 25 23 0,000 0,11330722 0,14081465 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11330722 0,14074195 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11330722 0,14066933 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11330722 0,14059678 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,11793308 0,14626134 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11793308 0,14618598 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,11793308 0,14611071 ! vesicle docking GO:0048278 47 24 0,000 0,11793308 0,14603551 ! spinal cord development GO:0021510 47 24 0,000 0,11793308 0,14596039 ! vacuole organization GO:0007033 43 24 0,000 0,11793308 0,14588534 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11793308 0,14581038 ! digestive system process GO:0022600 39 24 0,000 0,11793308 0,14573549 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11793308 0,14566067 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11793308 0,14558594 ! regulation of behavior GO:0050795 43 24 0,000 0,11793308 0,14551128 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,11793308 0,1454367 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11793308 0,14536219 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,11793308 0,14528776 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,11793308 0,14521341 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11793308 0,14513913 ! membrane depolarization GO:0051899 39 24 0,000 0,11793308 0,14506493 ! pentose metabolic process GO:0019321 35 24 0,000 0,11793308 0,1449908 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,11793308 0,14491675 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11793308 0,14484277 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11793308 0,14476887 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11793308 0,14469505 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11793308 0,1446213 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11793308 0,14454763 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11793308 0,14447403 ! regulation of amine transport GO:0051952 40 24 0,000 0,11793308 0,14440051 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,12253497 0,14995886 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12253497 0,14988263 ! phototransduction GO:0007602 33 25 0,000 0,12253497 0,14980647 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12253497 0,14973038 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,12253497 0,14965438 ! sperm motility GO:0030317 31 25 0,000 0,12253497 0,14957845 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12253497 0,1495026 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,12253497 0,14942683 ! receptor metabolic process GO:0043112 46 25 0,000 0,12253497 0,14935113 ! chromosome condensation GO:0030261 45 25 0,000 0,12253497 0,14927551 ! response to starvation GO:0042594 42 25 0,000 0,12253497 0,14919996 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12253497 0,1491245 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,12253497 0,1490491 ! neural crest cell development GO:0014032 54 25 0,000 0,12253497 0,14897379 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 0,000 0,12253497 0,14889855 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12253497 0,14882339 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12253497 0,1487483 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12253497 0,14867329 ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12253497 0,14859835 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12253497 0,14852349 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12253497 0,1484487 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,12253497 0,14837399 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12253497 0,14829936 ! telomere organization GO:0032200 43 25 0,000 0,12253497 0,1482248 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12253497 0,14815032 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12253497 0,14807591 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12711299 0,15353106 ! embryonic pattern specification GO:0009880 44 26 0,000 0,12711299 0,15345402 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12711299 0,15337706 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12711299 0,15330018 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12711299 0,15322338 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,12711299 0,15314665 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,12711299 0,15307 ! molting cycle process GO:0022404 50 26 0,000 0,12711299 0,15299343 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,12711299 0,15291693 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12711299 0,15284051 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,12711299 0,15276417 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,12711299 0,1526879 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,12711299 0,15261171 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12711299 0,15253559 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12711299 0,15245955 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12711299 0,15238359 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,12711299 0,1523077 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,12711299 0,15223189 ! blastocyst development GO:0001824 49 26 0,000 0,12711299 0,15215615 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12711299 0,15208049 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12711299 0,1520049 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,12711299 0,15192939 ! neuron fate commitment GO:0048663 48 27 0,000 0,13166729 0,15729468 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,13166729 0,15721662 ! iron ion transport GO:0006826 59 27 0,000 0,13166729 0,15713864 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13166729 0,15706073 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13166729 0,1569829 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13166729 0,15690515 ! fat cell differentiation GO:0045444 50 27 0,000 0,13166729 0,15682747 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13166729 0,15674987 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,13166729 0,15667235 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13166729 0,15659491 ! autophagy GO:0006914 41 27 0,000 0,13166729 0,15651754 ! male gonad development GO:0008584 44 27 0,000 0,13166729 0,15644024 ! response to toxin GO:0009636 47 27 0,000 0,13166729 0,15636303 ! primary neural tube formation GO:0014020 51 27 0,000 0,13166729 0,15628589 ! base-excision repair GO:0006284 41 27 0,000 0,13166729 0,15620882 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13166729 0,15613183 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13166729 0,15605492 ! glutathione metabolic process GO:0006749 39 27 0,000 0,13166729 0,15597809 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13166729 0,15590133 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13166729 0,15582464 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,13619797 0,16110733 ! circadian rhythm GO:0007623 50 28 0,000 0,13619797 0,16102816 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,13619797 0,16094907 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13619797 0,16087006 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,13619797 0,16079113 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13619797 0,16071227 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,13619797 0,16063349 ! lipid oxidation GO:0034440 43 28 0,000 0,13619797 0,16055478 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13619797 0,16047616 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,13619797 0,16039761 ! translational initiation GO:0006413 65 29 0,000 0,14070516 0,16562457 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14070516 0,16554358 ! regulation of pH GO:0006885 43 29 0,000 0,14070516 0,16546267 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14070516 0,16538184 ! catechol metabolic process GO:0009712 54 29 0,000 0,14070516 0,16530108 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14070516 0,16522041 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14070516 0,16513981 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14070516 0,1650593 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,14070516 0,16497886 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,14070516 0,1648985 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,14070516 0,16481822 ! cell fate determination GO:0001709 60 29 0,000 0,14070516 0,16473801 ! detection of light stimulus GO:0009583 38 29 0,000 0,14070516 0,16465789 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,14070516 0,16457784 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,14070516 0,16449787 ! regulation of coagulation GO:0050818 46 29 0,000 0,14070516 0,16441798 ! phenol metabolic process GO:0018958 55 30 0,000 0,14518899 0,1695751 ! zinc ion transport GO:0006829 45 30 0,000 0,14518899 0,16949282 ! membrane docking GO:0022406 61 30 0,000 0,14518899 0,16941062 ! cell junction assembly GO:0034329 78 30 0,000 0,14518899 0,1693285 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14518899 0,16924646 ! acute-phase response GO:0006953 49 30 0,000 0,14518899 0,1691645 ! myofibril assembly GO:0030239 47 30 0,000 0,14518899 0,16908262 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14518899 0,16900082 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14518899 0,1689191 ! phospholipid transport GO:0015914 51 30 0,000 0,14518899 0,16883746 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14518899 0,16875589 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14518899 0,16867441 ! eye morphogenesis GO:0048592 60 30 0,000 0,14518899 0,168593 ! regulation of B cell activation GO:0050864 50 30 0,000 0,14518899 0,16851167 ! response to heat GO:0009408 50 30 0,000 0,14518899 0,16843042 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,14964956 0,17352137 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,14964956 0,17343779 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,14964956 0,17335428 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,14964956 0,17327086 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,14964956 0,17318752 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,14964956 0,17310425 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,14964956 0,17302107 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,14964956 0,17293797 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,14964956 0,17285494 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,14964956 0,172772 ! peptide transport GO:0015833 55 31 0,000 0,14964956 0,17268913 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,14964956 0,17260635 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,14964956 0,17252364 ! mesoderm formation GO:0001707 69 31 0,000 0,14964956 0,17244102 ! natural killer cell activation GO:0030101 45 31 0,000 0,14964956 0,17235847 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,14964956 0,172276 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,14964956 0,17219361 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,14964956 0,1721113 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,14964956 0,17202907 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,14964956 0,17194692 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15408701 0,17696102 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15408701 0,17687659 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15408701 0,17679225 ! cholesterol transport GO:0030301 56 32 0,000 0,15408701 0,17670798 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15408701 0,17662379 ! spliceosome assembly GO:0000245 67 32 0,000 0,15408701 0,17653969 ! spindle organization GO:0007051 46 32 0,000 0,15408701 0,17645566 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15408701 0,17637171 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15408701 0,17628785 ! response to ionizing radiation GO:0010212 65 32 0,000 0,15408701 0,17620406 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15408701 0,17612035 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,15408701 0,17603672 ! muscle cell development GO:0055001 49 32 0,000 0,15408701 0,17595318 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15408701 0,17586971 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15408701 0,17578632 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15408701 0,17570301 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15408701 0,17561977 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15408701 0,17553662 ! gene silencing GO:0016458 65 32 0,000 0,15408701 0,17545355 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,15850145 0,18039474 ! post-embryonic development GO:0009791 69 33 0,000 0,15850145 0,18030945 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,15850145 0,18022423 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15850145 0,1801391 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15850145 0,18005405 ! formation of primary germ layer GO:0001704 72 33 0,000 0,15850145 0,17996908 ! cell fate specification GO:0001708 52 33 0,000 0,15850145 0,17988419 ! sterol transport GO:0015918 57 33 0,000 0,15850145 0,17979938 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,15850145 0,17971465 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,15850145 0,17962999 ! adult locomotory behavior GO:0008344 59 33 0,000 0,15850145 0,17954542 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15850145 0,17946093 ! glial cell differentiation GO:0010001 63 34 0,000 0,16289299 0,18434644 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16289299 0,18425977 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,16289299 0,18417318 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16289299 0,18408668 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16289299 0,18400025 ! spermatid development GO:0007286 63 34 0,000 0,16289299 0,18391391 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,16289299 0,18382764 ! placenta development GO:0001890 53 34 0,000 0,16289299 0,18374146 ! regulation of muscle development GO:0048634 70 35 0,000 0,16726176 0,18858098 ! negative regulation of secretion GO:0051048 63 35 0,000 0,16726176 0,18849265 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,16726176 0,1884044 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,16726176 0,18831624 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,16726176 0,18822816 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 0,000 0,16726176 0,18814016 ! cytokine production GO:0001816 59 35 0,000 0,16726176 0,18805225 ! neural tube formation GO:0001841 67 35 0,000 0,16726176 0,18796441 ! vesicle localization GO:0051648 64 35 0,000 0,16726176 0,18787666 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,17160788 0,19266849 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,17160788 0,19257862 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 0,000 0,17160788 0,19248884 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17160788 0,19239914 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,17160788 0,19230953 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,17160788 0,19222 ! regulation of proteolysis GO:0030162 72 36 0,000 0,17160788 0,19213056 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,17160788 0,19204119 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,17160788 0,19195191 ! embryonic organ development GO:0048568 57 36 0,000 0,17160788 0,19186272 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,17160788 0,1917736 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17593146 0,19651397 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,17593146 0,19642278 ! sister chromatid segregation GO:0000819 58 37 0,000 0,17593146 0,19633168 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17593146 0,19624066 ! organic anion transport GO:0015711 68 37 0,000 0,17593146 0,19614972 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,17593146 0,19605887 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,17593146 0,1959681 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17593146 0,19587741 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,17593146 0,19578681 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17593146 0,1956963 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,17593146 0,19560587 ! pigment metabolic process GO:0042440 80 37 0,000 0,17593146 0,19551552 ! spermatid differentiation GO:0048515 66 37 0,000 0,17593146 0,19542525 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18023262 0,2001106 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18023262 0,2000183 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18023262 0,19992608 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18023262 0,19983395 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,18023262 0,1997419 ! lipid homeostasis GO:0055088 67 38 0,000 0,18023262 0,19964994 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18023262 0,19955806 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,18023262 0,19946627 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18023262 0,19937456 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18023262 0,19928294 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,18023262 0,1991914 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18023262 0,19909994 ! glucan metabolic process GO:0044042 62 38 0,000 0,18023262 0,19900857 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,18451146 0,20363972 ! learning GO:0007612 77 39 0,000 0,18451146 0,20354635 ! organic ether metabolic process GO:0018904 55 39 0,000 0,18451146 0,20345306 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,18451146 0,20335986 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18451146 0,20326675 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18451146 0,20317372 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18451146 0,20308078 ! RNA modification GO:0009451 57 39 0,000 0,18451146 0,20298792 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18451146 0,20289515 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,18876812 0,20748109 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18876812 0,20738635 ! feeding behavior GO:0007631 59 40 0,000 0,18876812 0,20729169 ! negative regulation of binding GO:0051100 72 40 0,000 0,18876812 0,20719712 ! maintenance of protein location GO:0045185 91 40 0,000 0,18876812 0,20710264 ! cytokinesis GO:0000910 72 40 0,000 0,18876812 0,20700825 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1930027 0,21155558 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1930027 0,21145924 ! gliogenesis GO:0042063 88 41 0,000 0,1930027 0,21136299 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1930027 0,21126683 ! polyol metabolic process GO:0019751 66 41 0,000 0,1930027 0,21117076 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19721531 0,21568184 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,19721531 0,21558384 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,19721531 0,21548594 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,19721531 0,21538813 ! regulation of protein secretion GO:0050708 71 42 0,000 0,19721531 0,2152904 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,19721531 0,21519276 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,20140608 0,21966592 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,20140608 0,21956639 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20140608 0,21946695 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,20140608 0,21936759 ! glucose transport GO:0015758 65 43 0,000 0,20140608 0,21926833 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,20140608 0,21916916 ! striated muscle contraction GO:0006941 77 43 0,000 0,20140608 0,21907008 ! phagocytosis GO:0006909 90 43 0,000 0,20140608 0,21897109 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20140608 0,21887218 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,2055751 0,22330189 ! hexose transport GO:0008645 67 44 0,000 0,2055751 0,22320112 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,2055751 0,22310045 ! double-strand break repair GO:0006302 81 44 0,000 0,2055751 0,22299986 ! B cell differentiation GO:0030183 107 44 0,000 0,2055751 0,22289936 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,2055751 0,22279896 ! maintenance of location in cell GO:0051651 97 44 0,000 0,2055751 0,22269864 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,2097225 0,22708926 ! leukocyte migration GO:0050900 68 45 0,000 0,2097225 0,2269871 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,2097225 0,22688504 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,2097225 0,22678307 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,2097225 0,22668119 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,2097225 0,2265794 ! cell growth GO:0016049 84 45 0,000 0,2097225 0,22647771 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21384838 0,23082961 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,21384838 0,2307261 ! response to calcium ion GO:0051592 81 47 0,000 0,21795286 0,23504912 ! endosome transport GO:0016197 108 47 0,000 0,21795286 0,23494381 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,21795286 0,2348386 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,21795286 0,23473348 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,21795286 0,23462845 ! protein homooligomerization GO:0051260 76 47 0,000 0,21795286 0,23452352 ! mitochondrial transport GO:0006839 82 48 0,000 0,22203605 0,23881034 ! Notch signaling pathway GO:0007219 96 48 0,000 0,22203605 0,23870363 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,22203605 0,23859702 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,22203605 0,2384905 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,22203605 0,23838408 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,22203605 0,23827776 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,22609805 0,24252871 ! regulation of ion transport GO:0043269 77 49 0,000 0,22609805 0,24242064 ! peptide metabolic process GO:0006518 76 49 0,000 0,22609805 0,24231265 ! response to temperature stimulus GO:0009266 76 49 0,000 0,22609805 0,24220477 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,22609805 0,24209698 ! endocrine system development GO:0035270 104 49 0,000 0,22609805 0,24198928 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,22609805 0,24188168 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,22609805 0,24177418 ! inner ear development GO:0048839 79 50 0,000 0,23013898 0,24598595 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,23415894 0,25017158 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,23415894 0,25006054 ! excretion GO:0007588 83 51 0,000 0,23415894 0,2499496 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,23415894 0,24983876 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,23415894 0,24972802 ! vesicle organization GO:0016050 107 51 0,000 0,23415894 0,24961737 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,23815804 0,25376805 ! membrane fusion GO:0006944 110 52 0,000 0,23815804 0,25365571 ! amino acid activation GO:0043038 92 52 0,000 0,23815804 0,25354347 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 0,000 0,24213639 0,25766482 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,24213639 0,25755091 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,24213639 0,2574371 ! cell maturation GO:0048469 100 53 0,000 0,24213639 0,25732339 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,24213639 0,25720979 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,24213639 0,25709628 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,2460941 0,26118324 ! cell recognition GO:0008037 85 54 0,000 0,2460941 0,26106808 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,2460941 0,26095303 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,2460941 0,26083807 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,2460941 0,26072321 ! chloride transport GO:0006821 90 55 0,000 0,25003128 0,26477784 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,25003128 0,26466135 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,25003128 0,26454497 ! gastrulation GO:0007369 112 55 0,000 0,25003128 0,26442868 ! RNA elongation GO:0006354 79 55 0,000 0,25003128 0,2643125 ! regulation of actin filament length GO:0030832 105 56 0,000 0,25394802 0,26833506 ! sensory perception of smell GO:0007608 80 56 0,000 0,25394802 0,26821727 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,25394802 0,26809958 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,25394802 0,26798199 ! proton transport GO:0015992 94 56 0,000 0,25394802 0,2678645 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,25394802 0,26774712 ! hydrogen transport GO:0006818 97 58 0,000 0,26172063 0,27582122 ! adult behavior GO:0030534 99 58 0,000 0,26172063 0,27570045 ! positive regulation of secretion GO:0051047 95 59 0,000 0,26557671 0,27964007 ! regulation of cellular component size GO:0032535 109 59 0,000 0,26557671 0,27951774 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,26557671 0,27939552 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,26557671 0,27927341 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,26557671 0,2791514 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,26941277 0,28305988 ! regulation of heart contraction GO:0008016 110 60 0,000 0,26941277 0,28293633 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,26941277 0,28281289 ! mesoderm development GO:0007498 119 61 0,000 0,27322893 0,28669377 ! tRNA processing GO:0008033 89 61 0,000 0,27322893 0,28656879 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,27322893 0,28644392 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,27702528 0,2902974 ! regulation of mitosis GO:0007088 105 63 0,000 0,28080192 0,29412687 GO:0051783|regulation of nuclear division, ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,28080192 0,29399888 ! cell redox homeostasis GO:0045454 102 64 0,000 0,28455896 0,2978029 ! single fertilization GO:0007338 75 64 0,000 0,28455896 0,29767342 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,2882965 0,30145214 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,2882965 0,30132119 ! germ cell development GO:0007281 118 65 0,000 0,2882965 0,30119035 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,29201464 0,30494237 ! actin filament organization GO:0007015 148 66 0,000 0,29201464 0,30481007 ! extracellular matrix organization GO:0030198 133 66 0,000 0,29201464 0,30467789 ! secondary metabolic process GO:0019748 116 66 0,000 0,29201464 0,30454583 ! developmental maturation GO:0021700 116 66 0,000 0,29201464 0,30441387 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,29571347 0,30813626 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,29571347 0,30800286 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,29571347 0,30786959 ! chromosome segregation GO:0007059 113 67 0,000 0,29571347 0,30773643 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,29571347 0,30760338 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,29571347 0,30747045 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,29571347 0,30733763 ! activation of immune response GO:0002253 105 67 0,000 0,29571347 0,30720493 ! amino acid transport GO:0006865 125 68 0,000 0,29939311 0,31089332 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,29939311 0,3107592 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,29939311 0,31062519 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,29939311 0,3104913 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,29939311 0,31035752 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,30305364 0,31401682 ! negative regulation of cell size GO:0045792 134 69 0,000 0,30305364 0,31388164 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,30305364 0,31374658 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,30305364 0,31361164 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,30305364 0,31347681 ! amine catabolic process GO:0009310 117 71 0,000 0,31031778 0,32085285 ! humoral immune response GO:0006959 109 71 0,000 0,31031778 0,32071503 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,31031778 0,32057732 ! regulation of immune effector process GO:0002697 137 71 0,000 0,31031778 0,32043974 ! acute inflammatory response GO:0002526 113 72 0,000 0,31392159 0,32402203 ! carbohydrate transport GO:0008643 110 72 0,000 0,31392159 0,32388309 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,31392159 0,32374426 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,31392159 0,32360555 ! learning or memory GO:0007611 147 73 0,000 0,31750669 0,32716107 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31750669 0,32702102 ! fertilization GO:0009566 90 73 0,000 0,31750669 0,32688109 ! transition metal ion transport GO:0000041 126 74 0,000 0,32107318 0,33041149 ! neurotransmitter transport GO:0006836 123 74 0,000 0,32107318 0,33027023 ! exocytosis GO:0006887 133 74 0,000 0,32107318 0,33012909 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,32462114 0,33363455 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,32462114 0,33349209 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,32815068 0,3369742 ! defense response to bacterium GO:0042742 89 76 0,000 0,32815068 0,33683044 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3316619 0,34028935 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,3316619 0,3401443 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,3316619 0,33999937 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,33515488 0,34343383 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,33515488 0,34328763 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,33862971 0,34669919 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,33862971 0,34655172 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,33862971 0,34640438 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,34208651 0,34979181 ! response to metal ion GO:0010038 140 80 0,000 0,34208651 0,34964322 ! muscle cell differentiation GO:0042692 159 80 0,000 0,34208651 0,34949475 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,34208651 0,34934641 ! protein import into nucleus GO:0006606 158 80 0,000 0,34208651 0,34919819 ! inorganic anion transport GO:0015698 138 80 0,000 0,34208651 0,3490501 ! digestion GO:0007586 112 81 0,000 0,34552535 0,35240949 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,34552535 0,35226016 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,34552535 0,35211096 ! nuclear import GO:0051170 161 81 0,000 0,34552535 0,35196189 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,34894633 0,35529617 ! response to nutrient GO:0007584 125 82 0,000 0,34894633 0,35514588 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,34894633 0,35499571 ! regulation of lyase activity GO:0051339 160 83 0,000 0,35234954 0,35830642 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,35573507 0,36159636 ! negative regulation of growth GO:0045926 155 84 0,000 0,35573507 0,36144366 ! regulation of ligase activity GO:0051340 142 84 0,000 0,35573507 0,36129108 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,35573507 0,36113864 ! response to unfolded protein GO:0006986 131 85 0,000 0,35910302 0,36440399 ! nucleosome assembly GO:0006334 122 85 0,000 0,35910302 0,36425036 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,35910302 0,36409687 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,36245347 0,36733911 ! response to inorganic substance GO:0010035 153 86 0,000 0,36245347 0,36718444 ! chromatin assembly GO:0031497 124 86 0,000 0,36245347 0,3670299 ! amine transport GO:0015837 155 86 0,000 0,36245347 0,3668755 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,36578652 0,37009351 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,36578652 0,36993794 ! protein localization in nucleus GO:0034504 176 87 0,000 0,36578652 0,36978251 ! regulation of neurological system process GO:0031644 148 88 0,000 0,36910226 0,37297775 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,36910226 0,37282117 ! cellular defense response GO:0006968 114 89 0,000 0,37240077 0,37599507 ! ossification GO:0001503 188 90 0,000 0,37568214 0,379149 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,37568214 0,37899003 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,37568214 0,37883119 ! bone development GO:0060348 189 91 0,000 0,37894646 0,3819628 ! response to protein stimulus GO:0051789 149 91 0,000 0,37894646 0,38180285 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,37894646 0,38164303 ! nucleosome organization GO:0034728 138 92 0,000 0,38219383 0,38475245 ! vitamin metabolic process GO:0006766 139 92 0,000 0,38219383 0,38459153 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,38542432 0,38768015 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,38542432 0,38751815 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,38542432 0,38735628 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,38542432 0,38719454 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,38863803 0,39026006 ! female pregnancy GO:0007565 164 94 0,000 0,38863803 0,39009725 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,39501544 0,39633326 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,39501544 0,39616805 ! positive regulation of immune response GO:0050778 156 96 0,000 0,39501544 0,39600298 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,39817931 0,39900851 ! hormone metabolic process GO:0042445 157 97 0,000 0,39817931 0,39884239 ! response to virus GO:0009615 160 98 0,000 0,40132674 0,40182777 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,40132674 0,40166062 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,40132674 0,40149361 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,40445781 0,40445781