pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6111-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! filopodium assembly GO:0046847 42 17 3,000 1,315E-06 3,212E-03 ! microspike assembly GO:0030035 46 18 3,000 1,684E-06 2,057E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 4,000 1,824E-06 1,485E-03 ! nuclear migration GO:0007097 13 6 2,000 2,361E-06 1,442E-03 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 2,361E-06 1,154E-03 GO:0031272|regulation of pseudopodium assembly, ! N-terminal protein amino acid acetylation GO:0006474 14 7 2,000 4,117E-06 1,676E-03 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 6,563E-06 2,29E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 6,563E-06 2,004E-03 ! establishment of nucleus localization GO:0040023 18 8 2,000 6,563E-06 1,781E-03 ! regulation of DNA metabolic process GO:0051052 188 97 5,000 9,208E-06 2,25E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 9,327E-06 2,071E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 9,808E-06 1,997E-03 ! macrophage differentiation GO:0030225 15 9 2,000 9,808E-06 1,843E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 2,000 1,913E-05 3,337E-03 ! nucleus localization GO:0051647 22 11 2,000 1,913E-05 3,115E-03 ! cell projection assembly GO:0030031 138 68 4,000 2,277E-05 3,477E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 2,541E-05 3,651E-03 ! histone acetylation GO:0016573 27 12 2,000 2,541E-05 3,448E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 2,541E-05 3,267E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 3,76E-05 4,592E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 4,173E-05 4,855E-03 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 32 14 2,000 4,173E-05 4,634E-03 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 4,173E-05 4,433E-03 ! activation of protein kinase activity GO:0032147 170 80 4,000 5,006E-05 5,096E-03 ! positive regulation of biomineral formation GO:0070169 33 15 2,000 5,198E-05 5,079E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 5,198E-05 4,884E-03 ! dorsal/ventral pattern formation GO:0009953 75 42 3,000 5,614E-05 5,079E-03 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 6,696E-05 5,842E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 3,000 7,387E-05 6,223E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 8,775E-05 7,146E-03 ! proximal/distal pattern formation GO:0009954 33 19 2,000 1,091E-04 8,597E-03 ! positive regulation of ossification GO:0045778 50 20 2,000 1,279E-04 9,763E-03 ! protein amino acid acetylation GO:0006473 41 20 2,000 1,279E-04 9,467E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,279E-04 9,188E-03 ! negative regulation of translation GO:0017148 32 20 2,000 1,279E-04 8,926E-03 ! positive regulation of growth GO:0045927 96 53 3,000 1,408E-04 9,552E-03 ! positive regulation of osteoblast differentiation GO:0045669 52 21 2,000 1,486E-04 9,815E-03 ! positive regulation of bone remodeling GO:0046852 54 22 2,000 1,715E-04 0,01102503 GO:0034105|positive regulation of tissue remodeling, ! ureteric bud development GO:0001657 50 22 2,000 1,715E-04 0,01074233 ! regulation of DNA replication GO:0006275 105 56 3,000 1,745E-04 0,01065951 ! positive regulation of DNA replication GO:0045740 44 23 2,000 1,965E-04 0,01170835 ! regulation of bone mineralization GO:0030500 54 23 2,000 1,965E-04 0,01142958 ! positive regulation of cell migration GO:0030335 137 58 3,000 2,001E-04 0,01136626 ! aging GO:0007568 112 58 3,000 2,001E-04 0,01110794 ! kidney development GO:0001822 133 60 3,000 2,282E-04 0,01238748 ! positive regulation of helicase activity GO:0051096 12 5 1,000 2,414E-04 0,01282149 ! phosphatidic acid metabolic process GO:0046473 6 5 1,000 2,414E-04 0,01254869 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 2,414E-04 0,01228726 ! protein maturation by protein folding GO:0022417 14 5 1,000 2,414E-04 0,0120365 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,414E-04 0,01179577 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,414E-04 0,01156448 ! valine metabolic process GO:0006573 12 5 1,000 2,414E-04 0,01134208 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 2,414E-04 0,01112808 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,414E-04 0,01092201 ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 2,414E-04 0,01072343 ! sequestering of calcium ion GO:0051208 7 5 1,000 2,414E-04 0,01053194 ! phospholipid scrambling GO:0017121 8 5 1,000 2,414E-04 0,01034716 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 2,533E-04 0,01067084 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 2,533E-04 0,01048998 ! interaction with host GO:0051701 66 25 2,000 2,533E-04 0,01031515 ! regulation of biomineral formation GO:0070167 56 25 2,000 2,533E-04 0,01014604 ! skeletal system morphogenesis GO:0048705 118 63 3,000 2,755E-04 0,01085671 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 2,853E-04 0,01106499 ! regulation of osteoblast differentiation GO:0045667 68 26 2,000 2,853E-04 0,0108921 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 2,928E-04 0,0110036 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 2,928E-04 0,01083688 ! positive regulation of cell motion GO:0051272 157 65 3,000 3,108E-04 0,01133148 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 3,198E-04 0,01149093 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 3,295E-04 0,01166795 ! fatty acid biosynthetic process GO:0006633 139 67 3,000 3,491E-04 0,01218457 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 3,569E-04 0,01228128 ! protein amino acid acylation GO:0043543 59 28 2,000 3,569E-04 0,01211071 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 3,569E-04 0,01194481 ! cGMP-mediated signaling GO:0019934 14 6 1,000 3,609E-04 0,0119162 ! thymic T cell selection GO:0045061 16 6 1,000 3,609E-04 0,01175731 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 3,609E-04 0,01160261 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! neural nucleus development GO:0048857 19 6 1,000 3,609E-04 0,01145193 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 3,609E-04 0,01130511 ! neural tube patterning GO:0021532 8 6 1,000 3,609E-04 0,01116201 ! determination of adult lifespan GO:0008340 17 6 1,000 3,609E-04 0,01102248 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 3,908E-04 0,01178553 ! urogenital system development GO:0001655 149 69 3,000 3,908E-04 0,01164181 ! negative regulation of kinase activity GO:0033673 145 70 3,000 4,129E-04 0,01215182 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 4,391E-04 0,01277163 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 2,000 4,391E-04 0,01262138 ! sterol biosynthetic process GO:0016126 56 30 2,000 4,391E-04 0,01247462 ! appendage morphogenesis GO:0035107 150 72 3,000 4,597E-04 0,01290833 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 151 73 3,000 4,845E-04 0,01344969 GO:0060173|limb development, ! regulation of helicase activity GO:0051095 16 7 1,000 5,037E-04 0,01382579 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,037E-04 0,01367217 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 5,037E-04 0,01352192 GO:0031958|corticosteroid receptor signaling pathway, ! oxaloacetate metabolic process GO:0006107 13 7 1,000 5,037E-04 0,01337495 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,037E-04 0,01323113 ! male sex determination GO:0030238 15 7 1,000 5,037E-04 0,01309037 ! negative regulation of DNA recombination GO:0045910 16 7 1,000 5,037E-04 0,01295258 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 5,037E-04 0,01281766 ! regulation of meiosis GO:0040020 12 7 1,000 5,037E-04 0,01268552 GO:0051445|regulation of meiotic cell cycle, ! muscle adaptation GO:0043500 13 7 1,000 5,037E-04 0,01255607 ! negative regulation of transferase activity GO:0051348 155 74 3,000 5,102E-04 0,01258999 ! metanephros development GO:0001656 81 32 2,000 5,326E-04 0,01301141 ! BMP signaling pathway GO:0030509 71 32 2,000 5,326E-04 0,01288258 ! hindbrain development GO:0030902 65 32 2,000 5,326E-04 0,01275628 ! positive regulation of catabolic process GO:0009896 72 32 2,000 5,326E-04 0,01263243 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 6,379E-04 0,0149846 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 6,694E-04 0,01557444 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 1,000 6,694E-04 0,01542751 GO:0016446|somatic hypermutation of immunoglobulin genes, ! succinate metabolic process GO:0006105 17 8 1,000 6,694E-04 0,01528333 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 6,694E-04 0,01514181 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 6,694E-04 0,0150029 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 6,694E-04 0,01486651 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 6,694E-04 0,01473258 ! multicellular organismal aging GO:0010259 20 8 1,000 6,694E-04 0,01460103 ! regulation of respiratory burst GO:0060263 12 8 1,000 6,694E-04 0,01447182 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 8,578E-04 0,01838336 ! regulation of glycolysis GO:0006110 20 9 1,000 8,578E-04 0,0182235 ! microtubule bundle formation GO:0001578 22 9 1,000 8,578E-04 0,0180664 ! middle ear morphogenesis GO:0042474 14 9 1,000 8,578E-04 0,01791199 ! T cell selection GO:0045058 27 9 1,000 8,578E-04 0,01776019 ! retinal ganglion cell axon guidance GO:0031290 14 9 1,000 8,578E-04 0,01761095 ! regulation of telomere maintenance GO:0032204 17 9 1,000 8,578E-04 0,01746419 ! pyrimidine base metabolic process GO:0006206 22 9 1,000 8,578E-04 0,01731986 ! regulation of muscle adaptation GO:0043502 14 9 1,000 8,578E-04 0,01717789 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 8,863E-04 0,01760401 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 1,069E-03 0,02105727 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,069E-03 0,02088882 ! phosphagen metabolic process GO:0006599 17 10 1,000 1,069E-03 0,02072303 GO:0006600|creatine metabolic process, ! nucleobase biosynthetic process GO:0046112 26 10 1,000 1,069E-03 0,02055986 ! motor axon guidance GO:0008045 22 10 1,000 1,069E-03 0,02039923 ! protein heterooligomerization GO:0051291 17 10 1,000 1,069E-03 0,0202411 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,069E-03 0,0200854 GO:0045685|regulation of glial cell differentiation, ! positive regulation of phagocytosis GO:0050766 14 10 1,000 1,069E-03 0,01993208 ! regulation of developmental growth GO:0048638 16 10 1,000 1,069E-03 0,01978108 ! midbrain development GO:0030901 14 10 1,000 1,069E-03 0,01963235 ! musculoskeletal movement GO:0050881 16 10 1,000 1,069E-03 0,01948584 GO:0050879|multicellular organismal movement, ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,069E-03 0,0193415 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,069E-03 0,01919928 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,204E-03 0,02146377 ! positive regulation of transcription factor activity GO:0051091 71 43 2,000 1,273E-03 0,02254114 GO:0090047|positive regulation of transcription regulator activity, ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 1,302E-03 0,02288463 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,302E-03 0,02272117 ! keratinocyte proliferation GO:0043616 19 11 1,000 1,302E-03 0,02256003 ! blood vessel remodeling GO:0001974 30 11 1,000 1,302E-03 0,02240115 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 1,302E-03 0,0222445 ! DNA methylation GO:0006306 19 11 1,000 1,302E-03 0,02209003 GO:0006305|DNA alkylation, ! nitric oxide mediated signal transduction GO:0007263 26 11 1,000 1,302E-03 0,02193768 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 1,000 1,302E-03 0,02178742 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cardiac cell differentiation GO:0035051 36 11 1,000 1,302E-03 0,02163921 ! sequestering of metal ion GO:0051238 15 11 1,000 1,302E-03 0,021493 ! regulation of embryonic development GO:0045995 35 11 1,000 1,302E-03 0,02134875 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 1,454E-03 0,02367272 ! developmental growth GO:0048589 88 45 2,000 1,454E-03 0,02351594 ! leukocyte differentiation GO:0002521 232 98 3,000 1,461E-03 0,02348059 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,549E-03 0,02473797 ! pigmentation GO:0043473 103 46 2,000 1,549E-03 0,02457733 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,557E-03 0,02454672 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 1,557E-03 0,02438937 ! virus-host interaction GO:0019048 30 12 1,000 1,557E-03 0,02423402 ! hippocampus development GO:0021766 29 12 1,000 1,557E-03 0,02408064 ! entry into host cell GO:0030260 34 12 1,000 1,557E-03 0,02392919 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 17 12 1,000 1,557E-03 0,02377964 ! cranial nerve development GO:0021545 23 12 1,000 1,557E-03 0,02363194 ! immunoglobulin production during immune response GO:0002381 24 12 1,000 1,557E-03 0,02348606 ! autonomic nervous system development GO:0048483 24 12 1,000 1,557E-03 0,02334197 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,557E-03 0,02319965 GO:0042130|negative regulation of T cell proliferation, ! lamellipodium assembly GO:0030032 24 12 1,000 1,557E-03 0,02305904 ! skeletal muscle tissue development GO:0007519 223 100 3,000 1,574E-03 0,02316125 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA binding GO:0043388 83 48 2,000 1,753E-03 0,02563702 ! cartilage condensation GO:0001502 22 13 1,000 1,835E-03 0,02667795 ! positive regulation of cell growth GO:0030307 24 13 1,000 1,835E-03 0,02652009 ! plasma membrane organization GO:0007009 27 13 1,000 1,835E-03 0,02636409 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 1,000 1,835E-03 0,02620991 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 1,835E-03 0,02605753 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,835E-03 0,02590691 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of fatty acid oxidation GO:0046320 34 13 1,000 1,835E-03 0,02575802 ! JNK cascade GO:0007254 106 49 2,000 1,86E-03 0,02596642 ! regulation of ossification GO:0030278 123 50 2,000 1,972E-03 0,02736767 ! regulation of cell projection organization GO:0031344 135 51 2,000 2,087E-03 0,02880943 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 2,000 2,087E-03 0,02864758 ! retina development in camera-type eye GO:0060041 28 14 1,000 2,133E-03 0,02911667 ! negative regulation of caspase activity GO:0043154 23 14 1,000 2,133E-03 0,02895491 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 2,133E-03 0,02879494 ! positive regulation of binding GO:0051099 88 52 2,000 2,207E-03 0,02962599 ! histone modification GO:0016570 104 52 2,000 2,207E-03 0,0294641 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 2,207E-03 0,02930397 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 2,331E-03 0,03078277 ! cartilage development GO:0051216 99 53 2,000 2,331E-03 0,03061727 ! synapse organization GO:0050808 102 53 2,000 2,331E-03 0,03045354 ! regulation of mRNA processing GO:0050684 26 15 1,000 2,454E-03 0,03188392 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 1,000 2,454E-03 0,03171523 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,454E-03 0,0315483 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 2,454E-03 0,03138313 ! covalent chromatin modification GO:0016569 115 54 2,000 2,459E-03 0,03129187 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,459E-03 0,03112973 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,795E-03 0,03519713 ! positive regulation of cell size GO:0045793 29 16 1,000 2,795E-03 0,03501664 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 2,795E-03 0,03483798 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 2,795E-03 0,03466114 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 1,000 2,795E-03 0,03448608 ! regulation of dephosphorylation GO:0035303 43 16 1,000 2,795E-03 0,03431278 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 2,795E-03 0,03414122 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of bone remodeling GO:0046850 143 57 2,000 2,87E-03 0,03488033 ! heart morphogenesis GO:0003007 105 57 2,000 2,87E-03 0,03470765 ! regulation of tissue remodeling GO:0034103 146 58 2,000 3,015E-03 0,03628917 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 3,157E-03 0,03781156 ! negative regulation of peptidase activity GO:0010466 28 17 1,000 3,157E-03 0,03762711 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,157E-03 0,03744445 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 3,157E-03 0,03726356 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 3,157E-03 0,03708441 GO:0031114|regulation of microtubule depolymerization, ! nucleobase metabolic process GO:0009112 43 17 1,000 3,157E-03 0,03690697 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 3,157E-03 0,03673123 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 3,157E-03 0,03655714 ! establishment of organelle localization GO:0051656 122 59 2,000 3,166E-03 0,03647815 ! limbic system development GO:0021761 40 18 1,000 3,541E-03 0,04060843 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 3,541E-03 0,04041867 GO:0050886|endocrine process, ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 3,541E-03 0,04023068 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 1,000 3,541E-03 0,04004443 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 3,541E-03 0,03985989 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 3,541E-03 0,03967705 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 3,541E-03 0,03949587 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 3,541E-03 0,03931635 ! nerve development GO:0021675 34 18 1,000 3,541E-03 0,03913844 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,541E-03 0,03896214 ! viral reproductive process GO:0022415 132 62 2,000 3,643E-03 0,03990971 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 3,643E-03 0,03973155 ! regulation of homeostatic process GO:0032844 148 62 2,000 3,643E-03 0,03955496 ! regulation of protein complex assembly GO:0043254 132 63 2,000 3,811E-03 0,04120002 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 3,944E-03 0,04244864 ! cerebral cortex development GO:0021987 40 19 1,000 3,944E-03 0,04226246 ! neuromuscular junction development GO:0007528 43 19 1,000 3,944E-03 0,04207791 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 3,944E-03 0,04189496 ! protein export from nucleus GO:0006611 40 19 1,000 3,944E-03 0,0417136 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 3,944E-03 0,0415338 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 1,000 3,944E-03 0,04135554 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 4,345E-03 0,04535932 ! skin development GO:0043588 42 20 1,000 4,368E-03 0,04541183 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 4,368E-03 0,0452194 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 4,368E-03 0,0450286 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 4,368E-03 0,04483941 ! response to alkaloid GO:0043279 38 20 1,000 4,368E-03 0,0446518 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 4,368E-03 0,04446575 ! negative regulation of T cell activation GO:0050868 41 20 1,000 4,368E-03 0,04428124 ! activation of MAPK activity GO:0000187 124 67 2,000 4,532E-03 0,04575056 ! embryonic limb morphogenesis GO:0030326 139 67 2,000 4,532E-03 0,04556229 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 126 67 2,000 4,532E-03 0,04537556 ! viral reproduction GO:0016032 142 68 2,000 4,724E-03 0,047106 ! lipid phosphorylation GO:0046834 43 21 1,000 4,812E-03 0,04779227 ! ovarian follicle development GO:0001541 39 21 1,000 4,812E-03 0,04759878 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 4,812E-03 0,04740685 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 4,812E-03 0,04721646 ! regulation of vasoconstriction GO:0019229 40 21 1,000 4,812E-03 0,0470276 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 4,812E-03 0,04684023 ! positive regulation of inflammatory response GO:0050729 41 21 1,000 4,812E-03 0,04665436 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 4,921E-03 0,04751845 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 5,277E-03 0,05075076 ! inactivation of MAPK activity GO:0000188 45 22 1,000 5,277E-03 0,05055174 ! apoptotic nuclear changes GO:0030262 34 22 1,000 5,277E-03 0,05035427 ! cell aging GO:0007569 48 22 1,000 5,277E-03 0,05015834 ! renal system process GO:0003014 42 22 1,000 5,277E-03 0,04996393 ! cholesterol biosynthetic process GO:0006695 39 22 1,000 5,277E-03 0,04977102 ! somatic diversification of immunoglobulins GO:0016445 55 22 1,000 5,277E-03 0,04957959 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 1,000 5,277E-03 0,04938963 ! protein stabilization GO:0050821 41 22 1,000 5,277E-03 0,04920112 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 5,33E-03 0,04950755 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 5,76E-03 0,05330553 ! regulation of DNA recombination GO:0000018 51 23 1,000 5,76E-03 0,05310438 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 5,76E-03 0,05290474 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 5,76E-03 0,05270659 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 1,000 5,76E-03 0,05250993 ! DNA modification GO:0006304 36 23 1,000 5,76E-03 0,05231472 ! acetyl-CoA catabolic process GO:0046356 37 23 1,000 5,76E-03 0,05212097 GO:0006099|tricarboxylic acid cycle, ! regulation of caspase activity GO:0043281 136 74 2,000 5,98E-03 0,05390759 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 5,98E-03 0,0537094 ! organelle localization GO:0051640 155 74 2,000 5,98E-03 0,05351266 ! regulation of transcription factor activity GO:0051090 137 75 2,000 6,207E-03 0,05533946 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 6,207E-03 0,05513823 ! eye development GO:0001654 155 75 2,000 6,207E-03 0,05493845 ! axon guidance GO:0007411 162 75 2,000 6,207E-03 0,05474012 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 6,264E-03 0,05504424 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 6,264E-03 0,05484695 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 6,264E-03 0,05465107 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 6,264E-03 0,05445658 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 6,264E-03 0,05426348 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 6,264E-03 0,05407173 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 6,264E-03 0,05388134 ! sex determination GO:0007530 48 24 1,000 6,264E-03 0,05369228 ! pallium development GO:0021543 56 24 1,000 6,264E-03 0,05350455 ! oogenesis GO:0048477 44 24 1,000 6,264E-03 0,05331812 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 6,264E-03 0,05313299 ! pyrimidine nucleoside metabolic process GO:0006213 34 24 1,000 6,264E-03 0,05294914 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 6,264E-03 0,05276655 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 6,676E-03 0,05604263 ! regulation of catabolic process GO:0009894 173 77 2,000 6,676E-03 0,05585071 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 6,786E-03 0,05658402 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 6,786E-03 0,05639155 ! immunoglobulin production GO:0002377 62 25 1,000 6,786E-03 0,0562004 GO:0002440|production of molecular mediator of immune response, ! protein tetramerization GO:0051262 57 25 1,000 6,786E-03 0,05601053 ! steroid biosynthetic process GO:0006694 146 79 2,000 7,165E-03 0,05893587 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 7,328E-03 0,0600759 ! myelination GO:0042552 50 26 1,000 7,328E-03 0,05987498 ! initiation of viral infection GO:0019059 60 26 1,000 7,328E-03 0,0596754 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 7,328E-03 0,05947714 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 7,328E-03 0,05928019 ! coenzyme catabolic process GO:0009109 42 26 1,000 7,328E-03 0,05908455 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 1,000 7,328E-03 0,05889019 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somatic diversification of immune receptors GO:0002200 63 26 1,000 7,328E-03 0,05869711 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 2,000 7,417E-03 0,05921796 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 7,675E-03 0,06107546 ! acetyl-CoA metabolic process GO:0006084 41 27 1,000 7,889E-03 0,06257246 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 7,889E-03 0,06236996 ! cellular response to oxidative stress GO:0034599 43 27 1,000 7,889E-03 0,06216877 ! regulation of chromosome organization GO:0033044 49 27 1,000 7,889E-03 0,06196887 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 7,889E-03 0,06177025 ! regulation of peptidase activity GO:0052547 150 82 2,000 7,938E-03 0,06195663 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 8,206E-03 0,06384563 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 8,468E-03 0,06567533 ! dendrite development GO:0016358 67 28 1,000 8,468E-03 0,0654675 ! negative regulation of protein modification process GO:0031400 66 28 1,000 8,468E-03 0,06526097 ! regulation of systemic arterial blood pressure GO:0003073 55 28 1,000 8,468E-03 0,06505575 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 9,066E-03 0,06943063 ! somitogenesis GO:0001756 52 29 1,000 9,066E-03 0,06921366 ! synaptogenesis GO:0007416 46 29 1,000 9,066E-03 0,06899804 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 9,066E-03 0,06878376 ! mitochondrion organization GO:0007005 159 87 2,000 9,332E-03 0,07058041 ! cellular respiration GO:0045333 143 88 2,000 9,627E-03 0,07258518 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 9,682E-03 0,07278082 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 9,682E-03 0,07255757 ! tissue homeostasis GO:0001894 50 30 1,000 9,682E-03 0,07233568 GO:0048871|multicellular organismal homeostasis, ! regulation of DNA binding GO:0051101 167 89 2,000 9,927E-03 0,0739356 ! tube morphogenesis GO:0035239 194 89 2,000 9,927E-03 0,07371087 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01023223 0,07574954 ! ovulation cycle process GO:0022602 55 31 1,000 0,0103166 0,07614334 ! iron ion homeostasis GO:0055072 60 31 1,000 0,0103166 0,07591399 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,0103166 0,07568602 ! ensheathment of neurons GO:0007272 64 31 1,000 0,0103166 0,07545942 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 1,000 0,0103166 0,07523416 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,0103166 0,07501025 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 0,01096886 0,07951612 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01096886 0,07928086 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01096886 0,079047 ! ovulation cycle GO:0042698 57 32 1,000 0,01096886 0,07881451 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01096886 0,07858338 ! sterol metabolic process GO:0016125 166 94 2,000 0,01150882 0,08221069 ! regulation of membrane potential GO:0042391 179 94 2,000 0,01150882 0,081971 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,01163887 0,08265629 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01163887 0,0824167 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01232643 0,08703316 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01303136 0,09174525 ! positive regulation of endocytosis GO:0045807 56 35 1,000 0,01303136 0,09148162 ! telencephalon development GO:0021537 81 35 1,000 0,01303136 0,09121949 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,01375346 0,09599914 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 1,000 0,01375346 0,09572563 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 0,01375346 0,09545369 ! positive regulation of cell development GO:0010720 85 36 1,000 0,01375346 0,09518328 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01375346 0,0949144 ! aerobic respiration GO:0009060 56 36 1,000 0,01375346 0,09464703 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 1,000 0,01375346 0,09438117 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01449255 0,09917452 ! odontogenesis GO:0042476 74 37 1,000 0,01449255 0,09889749 ! tissue remodeling GO:0048771 78 37 1,000 0,01449255 0,09862201 ! female gonad development GO:0008585 71 37 1,000 0,01449255 0,09834806 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 0,01449255 0,09807563 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01449255 0,0978047 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01449255 0,09753527 ! meiosis I GO:0007127 74 38 1,000 0,01524845 0,10234058 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,01524845 0,10206019 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,01524845 0,10178134 ! regulation of protein stability GO:0031647 77 38 1,000 0,01524845 0,10150401 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,01602098 0,10635667 GO:0042593|glucose homeostasis, ! mammary gland development GO:0030879 93 40 1,000 0,01680995 0,11129189 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01680995 0,1109911 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,01680995 0,11069194 ! mismatch repair GO:0006298 58 40 1,000 0,01680995 0,11039438 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01680995 0,11009841 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,01761519 0,1150639 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,01761519 0,11475706 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,01761519 0,11445186 ! mesenchymal cell development GO:0014031 94 41 1,000 0,01761519 0,11414827 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,01843651 0,11915446 ! ear morphogenesis GO:0042471 64 42 1,000 0,01843651 0,11884007 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01843651 0,11852733 ! T cell differentiation GO:0030217 93 42 1,000 0,01843651 0,11821623 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 0,01843651 0,11790677 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,01843651 0,11759892 ! regulation of tube size GO:0035150 76 43 1,000 0,01927374 0,12261911 GO:0050880|regulation of blood vessel size, ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,01927374 0,12230061 ! segmentation GO:0035282 78 43 1,000 0,01927374 0,12198377 ! neuron migration GO:0001764 85 43 1,000 0,01927374 0,12166857 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,0201267 0,12672558 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 0,0201267 0,1263998 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,0201267 0,1260757 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,0201267 0,12575326 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,0201267 0,12543246 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02099522 0,13051226 ! ATP synthesis coupled electron transport GO:0042773 69 45 1,000 0,02099522 0,13018101 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 1,000 0,02099522 0,12985144 ! biopolymer methylation GO:0043414 91 45 1,000 0,02099522 0,12952353 ! female gamete generation GO:0007292 71 45 1,000 0,02099522 0,12919728 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 0,02187912 0,13429825 ! glycolysis GO:0006096 71 46 1,000 0,02187912 0,13396166 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,02187912 0,13362675 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02187912 0,13329352 ! neural tube development GO:0021915 91 47 1,000 0,02277824 0,138426 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,02369241 0,14362419 ! positive regulation of defense response GO:0031349 88 48 1,000 0,02369241 0,14326869 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02369241 0,14291494 ! cellular component disassembly GO:0022411 89 48 1,000 0,02369241 0,14256293 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02369241 0,14221265 ! regulation of inflammatory response GO:0050727 84 48 1,000 0,02369241 0,14186409 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,02369241 0,14151724 ! methylation GO:0032259 97 48 1,000 0,02369241 0,14117207 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02451544 0,14572072 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02451544 0,14536703 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02451544 0,14501505 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02451544 0,14466478 ! neuron fate determination GO:0048664 7 5 0,000 0,02451544 0,14431619 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02451544 0,14396927 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02451544 0,14362402 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02451544 0,14328042 ! polyol transport GO:0015791 12 5 0,000 0,02451544 0,14293847 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02451544 0,14259814 ! response to superoxide GO:0000303 10 5 0,000 0,02451544 0,14225942 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02451544 0,14192232 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02451544 0,1415868 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02451544 0,14125287 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02451544 0,14092051 ! female meiosis GO:0007143 10 5 0,000 0,02451544 0,14058971 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02451544 0,14026046 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02451544 0,13993275 ! hypothalamus development GO:0021854 9 5 0,000 0,02451544 0,13960657 ! cobalt ion transport GO:0006824 11 5 0,000 0,02451544 0,1392819 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02451544 0,13895874 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02451544 0,13863708 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02451544 0,1383169 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02451544 0,1379982 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02451544 0,13768096 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02451544 0,13736518 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02451544 0,13705084 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02451544 0,13673794 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02451544 0,13642646 ! transposition GO:0032196 9 5 0,000 0,02451544 0,1361164 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02451544 0,13580775 ! negative chemotaxis GO:0050919 16 5 0,000 0,02451544 0,13550049 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02451544 0,13519462 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02451544 0,13489013 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02451544 0,134587 ! behavioral response to pain GO:0048266 10 5 0,000 0,02451544 0,13428524 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02451544 0,13398483 ! Notch receptor processing GO:0007220 11 5 0,000 0,02451544 0,13368575 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02451544 0,13338801 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02451544 0,13309159 ! micturition GO:0060073 9 5 0,000 0,02451544 0,13279649 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02451544 0,13250269 ! copulation GO:0007620 9 5 0,000 0,02451544 0,13221019 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02451544 0,13191898 ! bioluminescence GO:0008218 9 5 0,000 0,02451544 0,13162905 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02451544 0,13134039 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02451544 0,13105299 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02451544 0,13076685 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02451544 0,13048195 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02451544 0,1301983 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02451544 0,12991587 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02451544 0,12963467 ! grooming behavior GO:0007625 6 5 0,000 0,02451544 0,12935468 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02451544 0,1290759 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02451544 0,12879832 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02451544 0,12852193 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02451544 0,12824672 ! response to protozoan GO:0001562 13 5 0,000 0,02451544 0,12797269 ! lymph vessel development GO:0001945 10 5 0,000 0,02451544 0,12769982 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02451544 0,12742812 ! endochondral ossification GO:0001958 17 5 0,000 0,02451544 0,12715757 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02451544 0,12688817 ! single strand break repair GO:0000012 8 5 0,000 0,02451544 0,12661991 ! parathyroid gland development GO:0060017 14 5 0,000 0,02451544 0,12635278 ! anagen GO:0042640 7 5 0,000 0,02451544 0,12608677 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02451544 0,12582188 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02451544 0,12555811 ! cytokine secretion GO:0050663 15 5 0,000 0,02451544 0,12529543 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02451544 0,12503386 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02451544 0,12477337 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02451544 0,12451397 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02451544 0,12425564 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02451544 0,12399838 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02451544 0,12374218 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02451544 0,12348705 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02451544 0,12323296 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02451544 0,12297991 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02451544 0,1227279 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02451544 0,12247693 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02451544 0,12222697 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02451544 0,12197804 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02451544 0,12173012 ! microvillus organization GO:0032528 8 5 0,000 0,02451544 0,1214832 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02451544 0,12123728 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02451544 0,12099236 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02451544 0,12074842 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02451544 0,12050547 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02451544 0,12026349 ! polyol catabolic process GO:0046174 9 5 0,000 0,02451544 0,12002248 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02451544 0,11978243 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02451544 0,11954335 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02451544 0,11930521 ! muscle cell migration GO:0014812 8 5 0,000 0,02451544 0,11906803 ! mitochondrial fission GO:0000266 8 5 0,000 0,02451544 0,11883178 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02451544 0,11859647 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02451544 0,11836209 ! mRNA transcription GO:0009299 10 5 0,000 0,02451544 0,11812863 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02451544 0,1178961 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02451544 0,11766447 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02451544 0,11743376 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02451544 0,11720395 ! monocyte activation GO:0042117 10 5 0,000 0,02451544 0,11697503 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02451544 0,11674701 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02451544 0,11651988 ! response to food GO:0032094 6 5 0,000 0,02451544 0,11629363 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02451544 0,11606825 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02451544 0,11584375 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02451544 0,11562011 ! forebrain neuron development GO:0021884 13 5 0,000 0,02451544 0,11539734 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02451544 0,11517542 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02451544 0,11495435 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02451544 0,11473413 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02451544 0,11451476 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02451544 0,11429622 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02451544 0,11407851 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02451544 0,11386163 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02451544 0,11364557 ! lipid glycosylation GO:0030259 7 5 0,000 0,02451544 0,11343034 ! nucleobase transport GO:0015851 6 5 0,000 0,02451544 0,11321591 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02451544 0,1130023 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02451544 0,11278949 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02451544 0,11257748 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02451544 0,11236626 ! basic amino acid transport GO:0015802 12 5 0,000 0,02451544 0,11215584 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02451544 0,1119462 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02451544 0,11173735 ! actin nucleation GO:0045010 11 5 0,000 0,02451544 0,11152927 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02451544 0,11132197 ! depurination GO:0045007 5 5 0,000 0,02451544 0,11111543 ! depyrimidination GO:0045008 10 5 0,000 0,02451544 0,11090966 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02451544 0,11070465 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02451544 0,1105004 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02451544 0,1102969 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02451544 0,11009415 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02451544 0,10989214 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02451544 0,10969087 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02451544 0,10949034 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02451544 0,10929054 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02451544 0,10909147 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02451544 0,10889312 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02451544 0,10869549 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02451544 0,10849858 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02451544 0,10830238 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02451544 0,10810689 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02451544 0,1079121 ! response to arsenic GO:0046685 11 5 0,000 0,02451544 0,10771802 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02451544 0,10752463 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02451544 0,10733193 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02451544 0,10713992 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02451544 0,1069486 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02451544 0,10675796 ! response to mercury ion GO:0046689 8 5 0,000 0,02451544 0,106568 ! response to cadmium ion GO:0046686 7 5 0,000 0,02451544 0,10637872 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02451544 0,1061901 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02451544 0,10600215 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02451544 0,10581487 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02451544 0,10562825 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02451544 0,10544228 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02451544 0,10525697 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02451544 0,10507231 ! decidualization GO:0046697 11 5 0,000 0,02451544 0,1048883 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02451544 0,10470493 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02451544 0,10452219 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02451544 0,1043401 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02451544 0,10415864 ! embryonic cleavage GO:0040016 6 5 0,000 0,02451544 0,10397781 ! peroxisome fission GO:0016559 5 5 0,000 0,02451544 0,1037976 ! histone demethylation GO:0016577 13 5 0,000 0,02451544 0,10361802 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02451544 0,10343906 ! mitotic recombination GO:0006312 9 5 0,000 0,02451544 0,10326072 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02451544 0,10308299 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02451544 0,10290587 ! metaphase plate congression GO:0051310 7 5 0,000 0,02451544 0,10272936 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02451544 0,10255345 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02451544 0,10237815 ! enteric nervous system development GO:0048484 8 5 0,000 0,02451544 0,10220344 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02451544 0,10202933 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02451544 0,10185581 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02451544 0,10168288 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02451544 0,10151054 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02451544 0,10133878 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02451544 0,1011676 ! B cell homeostasis GO:0001782 13 5 0,000 0,02451544 0,10099699 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02451544 0,10082697 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02451544 0,10065751 ! metaphase GO:0051323 11 5 0,000 0,02451544 0,10048862 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02451544 0,1003203 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02451544 0,10015254 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02451544 0,09998534 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02451544 0,0998187 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02451544 0,09965261 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02451544 0,09948707 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02451544 0,09932208 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02451544 0,09915764 ! response to redox state GO:0051775 6 5 0,000 0,02451544 0,09899375 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02451544 0,09883039 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02451544 0,09866757 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02451544 0,09850529 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02451544 0,09834354 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02451544 0,09818232 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02451544 0,09802163 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02451544 0,09786147 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02451544 0,09770182 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02451544 0,0975427 ! striatum development GO:0021756 14 5 0,000 0,02451544 0,09738409 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02451544 0,097226 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02451544 0,09706842 ! glial cell migration GO:0008347 10 5 0,000 0,02451544 0,09691135 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02451544 0,09675479 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02451544 0,09659874 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02451544 0,09644318 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02451544 0,09628813 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02451544 0,09613357 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02451544 0,09597951 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02451544 0,09582595 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02451544 0,09567287 ! neuroprotection GO:0043526 8 5 0,000 0,02451544 0,09552028 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02451544 0,09536818 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02451544 0,09521656 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02451544 0,09506542 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02451544 0,09491477 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02451544 0,09476458 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02451544 0,09461488 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02451544 0,09446564 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02451544 0,09431688 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02451544 0,09416858 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02451544 0,09402075 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02451544 0,09387338 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02451544 0,09372647 ! spindle assembly GO:0051225 6 5 0,000 0,02451544 0,09358003 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02451544 0,09343404 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02451544 0,0932885 ! protein palmitoylation GO:0018345 12 5 0,000 0,02451544 0,09314342 ! drug metabolic process GO:0017144 7 5 0,000 0,02451544 0,09299878 ! stem cell division GO:0017145 11 5 0,000 0,02451544 0,0928546 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02451544 0,09271086 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02451544 0,09256757 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02451544 0,09242472 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02462144 0,09268133 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 0,02462144 0,09253875 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,02462144 0,0923966 ! regulation of action potential GO:0001508 102 50 1,000 0,02556518 0,09579102 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,02556518 0,09564433 ! activation of caspase activity GO:0006919 95 50 1,000 0,02556518 0,09549808 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,02556518 0,09535228 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,02556518 0,09520693 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02556518 0,09506202 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,02556518 0,09491755 ! viral infectious cycle GO:0019058 104 51 1,000 0,02652347 0,09832599 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02652347 0,09817701 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02652347 0,09802848 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02749612 0,10146982 ! respiratory electron transport chain GO:0022904 83 53 1,000 0,02848299 0,10495314 ! chromatin remodeling GO:0006338 122 53 1,000 0,02848299 0,10479508 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,02848299 0,10463749 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02934634 0,1076473 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02934634 0,10748591 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02934634 0,107325 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02934634 0,10716458 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02934634 0,10700463 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02934634 0,10684516 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02934634 0,10668616 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02934634 0,10652764 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02934634 0,10636959 ! response to oxygen radical GO:0000305 11 6 0,000 0,02934634 0,106212 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02934634 0,10605488 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02934634 0,10589823 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02934634 0,10574204 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02934634 0,1055863 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02934634 0,10543103 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02934634 0,10527621 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02934634 0,10512185 ! forebrain regionalization GO:0021871 9 6 0,000 0,02934634 0,10496794 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02934634 0,10481448 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02934634 0,10466146 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02934634 0,10450889 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02934634 0,10435677 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02934634 0,10420509 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02934634 0,10405385 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02934634 0,10390304 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02934634 0,10375268 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02934634 0,10360275 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02934634 0,10345325 ! malate metabolic process GO:0006108 13 6 0,000 0,02934634 0,10330418 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02934634 0,10315554 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02934634 0,10300733 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02934634 0,10285954 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02934634 0,10271218 ! protein refolding GO:0042026 15 6 0,000 0,02934634 0,10256524 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02934634 0,10241872 ! opsonization GO:0008228 8 6 0,000 0,02934634 0,10227261 ! mating behavior GO:0007617 7 6 0,000 0,02934634 0,10212692 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02934634 0,10198165 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02934634 0,10183679 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02934634 0,10169234 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02934634 0,1015483 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02934634 0,10140467 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02934634 0,10126144 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02934634 0,10111862 ! toxin metabolic process GO:0009404 11 6 0,000 0,02934634 0,1009762 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02934634 0,10083418 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02934634 0,10069256 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02934634 0,10055133 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02934634 0,10041051 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02934634 0,10027007 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02934634 0,10013003 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02934634 0,09999038 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02934634 0,09985112 ! protein lipoylation GO:0009249 10 6 0,000 0,02934634 0,09971224 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02934634 0,09957375 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02934634 0,09943565 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02934634 0,09929792 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02934634 0,09916058 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02934634 0,09902362 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02934634 0,09888704 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02934634 0,09875083 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02934634 0,09861499 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02934634 0,09847953 ! hyperosmotic response GO:0006972 10 6 0,000 0,02934634 0,09834445 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02934634 0,09820973 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02934634 0,09807538 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02934634 0,09794139 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02934634 0,09780778 ! urea metabolic process GO:0019627 7 6 0,000 0,02934634 0,09767452 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02934634 0,09754163 ! neutrophil activation GO:0042119 7 6 0,000 0,02934634 0,0974091 ! regulation of appetite GO:0032098 10 6 0,000 0,02934634 0,09727693 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02934634 0,09714512 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02934634 0,09701367 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02934634 0,09688257 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02934634 0,09675182 ! neuron apoptosis GO:0051402 15 6 0,000 0,02934634 0,09662143 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02934634 0,09649139 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02934634 0,09636169 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02934634 0,09623235 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02934634 0,09610335 ! carnitine transport GO:0015879 10 6 0,000 0,02934634 0,0959747 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02934634 0,09584639 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02934634 0,09571843 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02934634 0,0955908 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02934634 0,09546352 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02934634 0,09533657 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02934634 0,09520996 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02934634 0,09508369 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02934634 0,09495775 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02934634 0,09483214 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02934634 0,09470687 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02934634 0,09458193 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02934634 0,09445731 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,02934634 0,09433303 ! astrocyte development GO:0014002 16 6 0,000 0,02934634 0,09420907 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02934634 0,09408543 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02934634 0,09396212 ! interaction with symbiont GO:0051702 14 6 0,000 0,02934634 0,09383914 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02934634 0,09371647 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02934634 0,09359413 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02934634 0,0934721 ! response to copper ion GO:0046688 10 6 0,000 0,02934634 0,09335039 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02934634 0,093229 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02934634 0,09310792 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02934634 0,09298716 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02934634 0,09286671 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02934634 0,09274657 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02934634 0,09262675 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02934634 0,09250723 ! hair follicle maturation GO:0048820 8 6 0,000 0,02934634 0,09238802 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02934634 0,09226911 ! Schwann cell development GO:0014044 15 6 0,000 0,02934634 0,09215052 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02934634 0,09203222 ! response to pheromone GO:0019236 6 6 0,000 0,02934634 0,09191423 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02934634 0,09179654 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02934634 0,09167916 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02934634 0,09156207 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02934634 0,09144528 ! subpallium development GO:0021544 15 6 0,000 0,02934634 0,09132879 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02934634 0,0912126 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02934634 0,0910967 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02934634 0,09098109 ! G2 phase GO:0051319 16 6 0,000 0,02934634 0,09086578 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02934634 0,09075076 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02934634 0,09063603 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02934634 0,09052159 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02934634 0,09040744 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02934634 0,09029358 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02934634 0,09018 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02934634 0,09006671 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02934634 0,0899537 ! receptor internalization GO:0031623 11 6 0,000 0,02934634 0,08984098 ! plasminogen activation GO:0031639 9 6 0,000 0,02934634 0,08972854 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02934634 0,08961638 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02934634 0,0895045 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02934634 0,08939289 ! protein deubiquitination GO:0016579 16 6 0,000 0,02934634 0,08928157 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02934634 0,08917052 ! protein destabilization GO:0031648 9 6 0,000 0,02934634 0,08905975 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02934634 0,08894926 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02934634 0,08883903 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02934634 0,08872909 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02934634 0,08861941 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02934634 0,08851 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02934634 0,08840086 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02934634 0,088292 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02934634 0,0881834 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02934634 0,08807506 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02934634 0,087967 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02934634 0,08785919 ! neural plate development GO:0001840 9 6 0,000 0,02934634 0,08775165 ! catecholamine transport GO:0051937 9 6 0,000 0,02934634 0,08764438 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02934634 0,08753736 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02934634 0,08743061 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02934634 0,08732412 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02934634 0,08721788 ! maternal placenta development GO:0001893 12 6 0,000 0,02934634 0,08711191 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02934634 0,08700619 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02934634 0,08690073 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02934634 0,08679552 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02934634 0,08669057 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02934634 0,08658587 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02934634 0,08648142 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02934634 0,08637723 GO:0055081|anion homeostasis, ! regulation of angiogenesis GO:0045765 125 54 1,000 0,0294839 0,08667769 ! regulation of translational initiation GO:0006446 87 54 1,000 0,0294839 0,08657351 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,0294839 0,08646958 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 1,000 0,0294839 0,0863659 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,0294839 0,08626247 ! regulation of cell shape GO:0008360 142 54 1,000 0,0294839 0,08615928 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03049869 0,08901829 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 0,03049869 0,08891206 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03049869 0,08880609 ! response to UV GO:0009411 120 55 1,000 0,03049869 0,08870037 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03049869 0,0885949 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03152721 0,09147386 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,03152721 0,09136535 ! glucose catabolic process GO:0006007 88 56 1,000 0,03152721 0,09125709 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03152721 0,0911491 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,0325693 0,0940506 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,0325693 0,09393956 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 1,000 0,0325693 0,09382878 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0325693 0,09371826 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,0325693 0,09360801 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,0336248 0,09652806 ! maintenance of location GO:0051235 124 58 1,000 0,0336248 0,09641477 ! tRNA transcription GO:0009304 17 7 0,000 0,03415345 0,09781579 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03415345 0,09770125 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03415345 0,09758698 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03415345 0,09747298 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03415345 0,09735924 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03415345 0,09724577 ! sleep GO:0030431 16 7 0,000 0,03415345 0,09713256 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03415345 0,09701961 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03415345 0,09690693 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03415345 0,09679451 ! prostate gland development GO:0030850 14 7 0,000 0,03415345 0,09668235 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03415345 0,09657045 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03415345 0,09645881 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03415345 0,09634742 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03415345 0,0962363 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03415345 0,09612542 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03415345 0,09601481 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03415345 0,09590445 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03415345 0,09579434 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03415345 0,09568448 ! glycolipid transport GO:0046836 11 7 0,000 0,03415345 0,09557488 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03415345 0,09546552 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03415345 0,09535642 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03415345 0,09524757 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03415345 0,09513896 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03415345 0,0950306 ! mRNA stabilization GO:0048255 18 7 0,000 0,03415345 0,09492249 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03415345 0,09481462 ! fibril organization GO:0043206 17 7 0,000 0,03415345 0,094707 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03415345 0,09459962 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03415345 0,09449249 ! lipoprotein transport GO:0042953 14 7 0,000 0,03415345 0,0943856 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03415345 0,09427895 ! rhythmic behavior GO:0007622 17 7 0,000 0,03415345 0,09417254 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03415345 0,09406637 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03415345 0,09396044 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03415345 0,09385475 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03415345 0,09374929 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03415345 0,09364407 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03415345 0,09353909 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03415345 0,09343434 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03415345 0,09332983 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03415345 0,09322555 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03415345 0,09312151 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03415345 0,09301769 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03415345 0,09291411 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03415345 0,09281075 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03415345 0,09270763 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03415345 0,09260474 ! spinal cord patterning GO:0021511 14 7 0,000 0,03415345 0,09250207 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03415345 0,09239963 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03415345 0,09229742 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03415345 0,09219543 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03415345 0,09209367 ! adrenal gland development GO:0030325 17 7 0,000 0,03415345 0,09199214 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03415345 0,09189082 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03415345 0,09178973 ! ovulation GO:0030728 10 7 0,000 0,03415345 0,09168887 ! adenohypophysis development GO:0021984 11 7 0,000 0,03415345 0,09158822 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03415345 0,09148779 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03415345 0,09138759 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03415345 0,0912876 ! microtubule nucleation GO:0007020 21 7 0,000 0,03415345 0,09118783 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03415345 0,09108828 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03415345 0,09098895 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03415345 0,09088984 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03415345 0,09079093 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03415345 0,09069225 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03415345 0,09059378 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03415345 0,09049552 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03415345 0,09039747 ! galactose metabolic process GO:0006012 13 7 0,000 0,03415345 0,09029964 ! vesicle fusion GO:0006906 20 7 0,000 0,03415345 0,09020202 ! response to dietary excess GO:0002021 8 7 0,000 0,03415345 0,09010461 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03415345 0,09000741 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03415345 0,08991042 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03415345 0,08981364 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03415345 0,08971706 ! organ growth GO:0035265 15 7 0,000 0,03415345 0,0896207 ! nucleoside transport GO:0015858 11 7 0,000 0,03415345 0,08952454 ! nucleoside salvage GO:0043174 11 7 0,000 0,03415345 0,08942858 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03415345 0,08933284 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03415345 0,08923729 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,03415345 0,08914195 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03415345 0,08904682 ! rRNA modification GO:0000154 14 7 0,000 0,03415345 0,08895189 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03415345 0,08885716 ! spindle checkpoint GO:0031577 16 7 0,000 0,03415345 0,08876263 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03415345 0,0886683 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03415345 0,08857417 ! monocyte differentiation GO:0030224 16 7 0,000 0,03415345 0,08848024 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03415345 0,08838651 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03415345 0,08829298 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03415345 0,08819965 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03415345 0,08810651 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03415345 0,08801357 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03415345 0,08792083 ! fibrinolysis GO:0042730 11 7 0,000 0,03415345 0,08782828 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03415345 0,08773593 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03415345 0,08764377 ! eating behavior GO:0042755 8 7 0,000 0,03415345 0,0875518 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03415345 0,08746003 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03415345 0,08736845 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03415345 0,08727706 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03415345 0,08718586 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03415345 0,08709485 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03415345 0,08700403 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03415345 0,0869134 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03415345 0,08682296 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03415345 0,08673271 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03415345 0,08664265 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03415345 0,08655277 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03415345 0,08646308 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03415345 0,08637357 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03415345 0,08628425 ! histone ubiquitination GO:0016574 9 7 0,000 0,03415345 0,08619511 ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03415345 0,08610616 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03415345 0,08601739 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03415345 0,0859288 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03415345 0,0858404 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03415345 0,08575218 ! transcription termination GO:0006353 14 7 0,000 0,03415345 0,08566414 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03415345 0,08557628 ! anaphase GO:0051322 18 7 0,000 0,03415345 0,08548859 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03415345 0,08540109 ! axonal fasciculation GO:0007413 19 7 0,000 0,03415345 0,08531377 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03415345 0,08522663 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03415345 0,08513966 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03415345 0,08505287 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03415345 0,08496626 ! diuresis GO:0030146 12 7 0,000 0,03415345 0,08487983 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03415345 0,08479357 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03415345 0,08470748 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03415345 0,08462157 ! antibiotic transport GO:0042891 9 7 0,000 0,03415345 0,08453583 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03415345 0,08445027 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03415345 0,08436488 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03415345 0,08427967 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03415345 0,08419462 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03415345 0,08410975 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03415345 0,08402504 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03415345 0,08394051 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03415345 0,08385615 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03415345 0,08377196 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03415345 0,08368793 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03415345 0,08360408 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03415345 0,08352039 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03415345 0,08343687 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03415345 0,08335352 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03415345 0,08327033 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03415345 0,08318731 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03415345 0,08310445 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03415345 0,08302176 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03415345 0,08293923 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03415345 0,08285687 ! retina homeostasis GO:0001895 12 7 0,000 0,03415345 0,08277467 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03415345 0,08269263 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03415345 0,08261076 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03415345 0,08252905 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03415345 0,0824475 ! nuclear export GO:0051168 110 59 1,000 0,03469354 0,08366864 ! lipid modification GO:0030258 112 60 1,000 0,03577539 0,08619257 ! DNA catabolic process GO:0006308 94 60 1,000 0,03577539 0,08610765 ! regulation of endocytosis GO:0030100 104 60 1,000 0,03577539 0,0860229 ! camera-type eye development GO:0043010 126 61 1,000 0,03687017 0,08856817 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,03797774 0,09113912 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03893688 0,09334917 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03893688 0,09325765 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,03893688 0,09316631 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03893688 0,09307515 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03893688 0,09298417 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03893688 0,09289336 ! male meiosis GO:0007140 9 8 0,000 0,03893688 0,09280274 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03893688 0,09271229 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03893688 0,09262201 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03893688 0,09253191 ! meiotic prophase I GO:0007128 14 8 0,000 0,03893688 0,09244199 ! response to zinc ion GO:0010043 12 8 0,000 0,03893688 0,09235224 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03893688 0,09226266 ! oligopeptide transport GO:0006857 16 8 0,000 0,03893688 0,09217326 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03893688 0,09208403 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03893688 0,09199498 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03893688 0,09190609 ! signal peptide processing GO:0006465 12 8 0,000 0,03893688 0,09181738 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03893688 0,09172884 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03893688 0,09164047 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03893688 0,09155227 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03893688 0,09146424 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03893688 0,09137637 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03893688 0,09128868 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03893688 0,09120116 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03893688 0,0911138 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03893688 0,09102661 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03893688 0,09093958 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03893688 0,09085273 ! reflex GO:0060004 17 8 0,000 0,03893688 0,09076604 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03893688 0,09067951 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03893688 0,09059315 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03893688 0,09050695 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03893688 0,09042092 ! pigment granule organization GO:0048753 17 8 0,000 0,03893688 0,09033505 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03893688 0,09024934 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03893688 0,0901638 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03893688 0,09007841 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03893688 0,08999319 ! histidine catabolic process GO:0006548 10 8 0,000 0,03893688 0,08990813 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03893688 0,08982323 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03893688 0,08973849 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03893688 0,08965392 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,03893688 0,0895695 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03893688 0,08948523 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03893688 0,08940113 ! melanin metabolic process GO:0006582 17 8 0,000 0,03893688 0,08931719 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03893688 0,0892334 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03893688 0,08914977 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03893688 0,0890663 ! macrophage activation GO:0042116 13 8 0,000 0,03893688 0,08898298 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03893688 0,08889982 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03893688 0,08881681 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03893688 0,08873396 ! purine salvage GO:0043101 12 8 0,000 0,03893688 0,08865126 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03893688 0,08856872 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03893688 0,08848633 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03893688 0,08840409 ! osteoblast development GO:0002076 17 8 0,000 0,03893688 0,08832201 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03893688 0,08824008 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03893688 0,0881583 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03893688 0,08807667 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03893688 0,08799519 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03893688 0,08791387 ! response to UV-B GO:0010224 17 8 0,000 0,03893688 0,08783269 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03893688 0,08775166 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03893688 0,08767079 ! intermediate filament organization GO:0045109 12 8 0,000 0,03893688 0,08759006 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03893688 0,08750948 ! cellular extravasation GO:0045123 13 8 0,000 0,03893688 0,08742905 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03893688 0,08734876 ! response to antibiotic GO:0046677 11 8 0,000 0,03893688 0,08726863 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03893688 0,08718864 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03893688 0,0871088 ! DNA topological change GO:0006265 12 8 0,000 0,03893688 0,0870291 ! response to tropane GO:0014073 15 8 0,000 0,03893688 0,08694955 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03893688 0,08687014 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03893688 0,08679088 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03893688 0,08671176 ! mast cell activation GO:0045576 14 8 0,000 0,03893688 0,08663279 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03893688 0,08655396 ! gas homeostasis GO:0033483 14 8 0,000 0,03893688 0,08647528 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03893688 0,08639673 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03893688 0,08631833 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03893688 0,08624008 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03893688 0,08616196 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03893688 0,08608399 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03893688 0,08600615 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03893688 0,08592846 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03893688 0,08585091 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03893688 0,08577349 ! response to tumor cell GO:0002347 16 8 0,000 0,03893688 0,08569622 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03893688 0,08561909 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03893688 0,08554209 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03893688 0,08546523 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03893688 0,08538851 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03893688 0,08531193 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03893688 0,08523549 ! hormone catabolic process GO:0042447 17 8 0,000 0,03893688 0,08515918 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03893688 0,08508301 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03893688 0,08500697 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03893688 0,08493108 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03893688 0,08485531 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03893688 0,08477968 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03893688 0,08470419 ! adult feeding behavior GO:0008343 10 8 0,000 0,03893688 0,08462883 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03893688 0,0845536 ! ATP catabolic process GO:0006200 11 8 0,000 0,03893688 0,08447851 ! blastocyst growth GO:0001832 19 8 0,000 0,03893688 0,08440355 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03893688 0,08432873 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03893688 0,08425403 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03893688 0,08417947 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03893688 0,08410504 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03893688 0,08403075 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03893688 0,08395658 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03893688 0,08388254 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03893688 0,08380864 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03893688 0,08373486 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03893688 0,08366122 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03893688 0,0835877 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03893688 0,08351431 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03893688 0,08344106 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03893688 0,08336793 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03893688 0,08329493 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03893688 0,08322205 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03893688 0,0831493 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03893688 0,08307669 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03893688 0,08300419 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03893688 0,08293183 ! glycerophospholipid biosynthetic process GO:0046474 116 64 1,000 0,04023065 0,08561278 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,04137568 0,08797282 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,04137568 0,08789633 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,04137568 0,08781996 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,04137568 0,08774373 ! ear development GO:0043583 114 66 1,000 0,04253289 0,09011957 ! gonad development GO:0008406 115 66 1,000 0,04253289 0,09004147 ! axon extension GO:0048675 16 9 0,000 0,04369676 0,09242527 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04369676 0,09234532 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04369676 0,09226551 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04369676 0,09218583 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04369676 0,09210629 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04369676 0,09202689 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04369676 0,09194762 ! reproductive behavior GO:0019098 22 9 0,000 0,04369676 0,0918685 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04369676 0,0917895 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04369676 0,09171065 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04369676 0,09163192 ! UTP metabolic process GO:0046051 10 9 0,000 0,04369676 0,09155334 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04369676 0,09147489 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,04369676 0,09139657 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04369676 0,09131839 ! artery development GO:0060840 25 9 0,000 0,04369676 0,09124034 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04369676 0,09116242 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04369676 0,09108464 ! equilibrioception GO:0050957 20 9 0,000 0,04369676 0,09100698 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04369676 0,09092947 ! chemosensory behavior GO:0007635 21 9 0,000 0,04369676 0,09085208 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04369676 0,09077482 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04369676 0,0906977 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04369676 0,09062071 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04369676 0,09054384 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04369676 0,09046711 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04369676 0,09039051 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04369676 0,09031404 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04369676 0,09023769 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04369676 0,09016148 ! protein targeting to ER GO:0045047 25 9 0,000 0,04369676 0,09008539 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04369676 0,09000944 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04369676 0,08993361 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04369676 0,08985791 ! glycine catabolic process GO:0006546 15 9 0,000 0,04369676 0,08978233 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04369676 0,08970688 ! endosome organization GO:0007032 20 9 0,000 0,04369676 0,08963156 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04369676 0,08955637 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04369676 0,0894813 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04369676 0,08940636 ! mannose metabolic process GO:0006013 13 9 0,000 0,04369676 0,08933154 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04369676 0,08925685 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04369676 0,08918228 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04369676 0,08910784 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04369676 0,08903352 ! receptor clustering GO:0043113 20 9 0,000 0,04369676 0,08895933 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04369676 0,08888526 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04369676 0,08881131 ! retinol metabolic process GO:0042572 20 9 0,000 0,04369676 0,08873748 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04369676 0,08866378 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04369676 0,0885902 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04369676 0,08851674 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04369676 0,08844341 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04369676 0,08837019 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04369676 0,0882971 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04369676 0,08822413 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04369676 0,08815127 ! response to amine stimulus GO:0014075 13 9 0,000 0,04369676 0,08807854 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04369676 0,08800593 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04369676 0,08793344 ! erythrocyte development GO:0048821 17 9 0,000 0,04369676 0,08786106 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04369676 0,08778881 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04369676 0,08771667 ! renal water homeostasis GO:0003091 15 9 0,000 0,04369676 0,08764466 ! postreplication repair GO:0006301 25 9 0,000 0,04369676 0,08757276 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04369676 0,08750098 ! icosanoid secretion GO:0032309 15 9 0,000 0,04369676 0,08742931 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04369676 0,08735777 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04369676 0,08728634 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04369676 0,08721503 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04369676 0,08714383 ! sterol catabolic process GO:0016127 14 9 0,000 0,04369676 0,08707275 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04369676 0,08700179 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04369676 0,08693094 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04369676 0,08686021 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04369676 0,08678959 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04369676 0,08671908 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04369676 0,0866487 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04369676 0,08657842 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04369676 0,08650826 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04369676 0,08643821 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04369676 0,08636828 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04369676 0,08629846 ! purine base metabolic process GO:0006144 25 9 0,000 0,04369676 0,08622875 ! pigment granule transport GO:0051904 17 9 0,000 0,04369676 0,08615915 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04369676 0,08608967 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04369676 0,0860203 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04369676 0,08595104 ! mitochondrion localization GO:0051646 18 9 0,000 0,04369676 0,08588189 ! hexose catabolic process GO:0019320 113 68 1,000 0,04488331 0,08814302 ! detection of external stimulus GO:0009581 102 68 1,000 0,04488331 0,08807222 ! regulation of lipase activity GO:0060191 137 68 1,000 0,04488331 0,08800154 ! adaptive immune response GO:0002250 126 68 1,000 0,04488331 0,08793097 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! lung development GO:0030324 165 69 1,000 0,04607621 0,09019566 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,0484332 0,09473364 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0484332 0,09465785 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0484332 0,09458219 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0484332 0,09450664 ! associative learning GO:0008306 21 10 0,000 0,0484332 0,09443122 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,0484332 0,09435591 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0484332 0,09428073 ! phosphate transport GO:0006817 24 10 0,000 0,0484332 0,09420566 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0484332 0,09413072 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0484332 0,09405589 ! CTP metabolic process GO:0046036 11 10 0,000 0,0484332 0,09398119 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0484332 0,0939066 ! GTP metabolic process GO:0046039 11 10 0,000 0,0484332 0,09383213 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0484332 0,09375778 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0484332 0,09368354 ! social behavior GO:0035176 29 10 0,000 0,0484332 0,09360943 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0484332 0,09353543 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0484332 0,09346154 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0484332 0,09338778 ! androgen metabolic process GO:0008209 17 10 0,000 0,0484332 0,09331413 ! phospholipid efflux GO:0033700 19 10 0,000 0,0484332 0,09324059 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0484332 0,09316718 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0484332 0,09309387 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0484332 0,09302069 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0484332 0,09294761 ! lung alveolus development GO:0048286 26 10 0,000 0,0484332 0,09287466 ! pathogenesis GO:0009405 17 10 0,000 0,0484332 0,09280181 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0484332 0,09272909 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0484332 0,09265647 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0484332 0,09258397 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0484332 0,09251158 ! endoderm development GO:0007492 18 10 0,000 0,0484332 0,09243931 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0484332 0,09236715 ! arginine catabolic process GO:0006527 17 10 0,000 0,0484332 0,0922951 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0484332 0,09222316 ! proline metabolic process GO:0006560 13 10 0,000 0,0484332 0,09215133 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0484332 0,09207962 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0484332 0,09200802 ! V(D)J recombination GO:0033151 34 10 0,000 0,0484332 0,09193653 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0484332 0,09186515 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0484332 0,09179388 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0484332 0,09172272 ! B cell proliferation GO:0042100 19 10 0,000 0,0484332 0,09165168 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0484332 0,09158074 ! multicellular organism growth GO:0035264 19 10 0,000 0,0484332 0,09150991 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0484332 0,09143919 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0484332 0,09136858 ! ruffle organization GO:0031529 17 10 0,000 0,0484332 0,09129808 ! epithelial cell development GO:0002064 21 10 0,000 0,0484332 0,09122769 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0484332 0,09115741 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0484332 0,09108723 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0484332 0,09101716 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0484332 0,0909472 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0484332 0,09087735 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0484332 0,09080761 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0484332 0,09073797 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0484332 0,09066844 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0484332 0,09059901 ! brain morphogenesis GO:0048854 23 10 0,000 0,0484332 0,0905297 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0484332 0,09046048 ! segment specification GO:0007379 15 10 0,000 0,0484332 0,09039138 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0484332 0,09032238 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0484332 0,09025348 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0484332 0,09018469 ! response to dsRNA GO:0043331 23 10 0,000 0,0484332 0,090116 ! DNA ligation GO:0006266 18 10 0,000 0,0484332 0,09004742 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0484332 0,08997895 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0484332 0,08991057 ! melanosome localization GO:0032400 16 10 0,000 0,0484332 0,0898423 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0484332 0,08977414 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0484332 0,08970608 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0484332 0,08963812 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0484332 0,08957026 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0484332 0,08950251 ! induction of an organ GO:0001759 17 10 0,000 0,0484332 0,08943486 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0484332 0,08936731 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0484332 0,08929986 ! protein sumoylation GO:0016925 17 10 0,000 0,0484332 0,08923251 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0484332 0,08916527 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0484332 0,08909813 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0484332 0,08903109 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0484332 0,08896415 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0484332 0,08889731 ! salivary gland development GO:0007431 28 10 0,000 0,0484332 0,08883057 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0484332 0,08876393 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0484332 0,08869739 ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0484332 0,08863095 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0484332 0,08856461 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0484332 0,08849836 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0484332 0,08843222 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0484332 0,08836618 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0484332 0,08830023 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0484332 0,08823439 ! detection of calcium ion GO:0005513 24 10 0,000 0,0484332 0,08816864 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0484332 0,08810299 ! blastocyst formation GO:0001825 18 10 0,000 0,0484332 0,08803744 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0484332 0,08797198 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0484332 0,08790662 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0484332 0,08784136 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0484332 0,0877762 ! response to nicotine GO:0035094 20 10 0,000 0,0484332 0,08771113 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0484332 0,08764616 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0484332 0,08758128 ! respiratory tube development GO:0030323 171 72 1,000 0,04972398 0,08984888 ! B cell activation GO:0042113 179 72 1,000 0,04972398 0,08978247 ! glycerolipid biosynthetic process GO:0045017 130 73 1,000 0,05096245 0,09195072 ! respiratory system development GO:0060541 175 74 1,000 0,05221197 0,09413567 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05314632 0,09574959 ! respiratory burst GO:0045730 17 11 0,000 0,05314632 0,09567903 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05314632 0,09560858 ! neuron fate specification GO:0048665 18 11 0,000 0,05314632 0,09553823 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05314632 0,09546798 ! thyroid gland development GO:0030878 26 11 0,000 0,05314632 0,09539783 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,05314632 0,09532779 ! synapsis GO:0007129 14 11 0,000 0,05314632 0,09525785 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05314632 0,09518801 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05314632 0,09511828 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05314632 0,09504864 ! response to pain GO:0048265 27 11 0,000 0,05314632 0,09497911 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05314632 0,09490968 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05314632 0,09484036 ! bone resorption GO:0045453 16 11 0,000 0,05314632 0,09477113 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05314632 0,094702 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05314632 0,09463298 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05314632 0,09456406 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05314632 0,09449523 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05314632 0,09442651 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05314632 0,09435788 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05314632 0,09428936 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05314632 0,09422094 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05314632 0,09415261 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05314632 0,09408438 ! UV protection GO:0009650 20 11 0,000 0,05314632 0,09401626 ! adult heart development GO:0007512 16 11 0,000 0,05314632 0,09394823 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05314632 0,0938803 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05314632 0,09381246 ! macroautophagy GO:0016236 19 11 0,000 0,05314632 0,09374473 ! temperature homeostasis GO:0001659 18 11 0,000 0,05314632 0,09367709 ! behavioral fear response GO:0001662 27 11 0,000 0,05314632 0,09360955 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05314632 0,09354211 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05314632 0,09347476 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05314632 0,09340752 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05314632 0,09334037 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05314632 0,09327331 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05314632 0,09320635 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05314632 0,09313949 ! regulation of organ growth GO:0046620 14 11 0,000 0,05314632 0,09307272 ! pigment granule localization GO:0051875 20 11 0,000 0,05314632 0,09300605 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05314632 0,09293948 ! vasoconstriction GO:0042310 20 11 0,000 0,05314632 0,092873 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05314632 0,09280661 ! embryonic axis specification GO:0000578 19 11 0,000 0,05314632 0,09274032 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05314632 0,09267412 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05314632 0,09260802 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05314632 0,09254202 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05314632 0,0924761 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05314632 0,09241028 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05314632 0,09234456 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05314632 0,09227893 ! prophase GO:0051324 17 11 0,000 0,05314632 0,09221339 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05314632 0,09214794 ! nucleosome positioning GO:0016584 15 11 0,000 0,05314632 0,09208259 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05314632 0,09201733 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05314632 0,09195216 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05314632 0,09188708 ! apical protein localization GO:0045176 18 11 0,000 0,05314632 0,0918221 ! acid secretion GO:0046717 20 11 0,000 0,05314632 0,09175721 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05314632 0,09169241 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05314632 0,0916277 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05314632 0,09156308 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05314632 0,09149855 ! thymus development GO:0048538 29 11 0,000 0,05314632 0,09143412 ! cholesterol efflux GO:0033344 21 11 0,000 0,05314632 0,09136977 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05314632 0,09130552 ! oocyte development GO:0048599 20 11 0,000 0,05314632 0,09124136 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05314632 0,09117728 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05314632 0,0911133 ! embryonic gut development GO:0048566 19 11 0,000 0,05314632 0,0910494 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05314632 0,0909856 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05314632 0,09092188 ! activation of innate immune response GO:0002218 16 11 0,000 0,05314632 0,09085826 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05314632 0,09079472 ! lysogeny GO:0030069 22 11 0,000 0,05314632 0,09073127 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05314632 0,09066791 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05314632 0,09060464 ! reproductive structure development GO:0048608 131 75 1,000 0,05347239 0,09109696 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,05347239 0,09103348 ! rhythmic process GO:0048511 142 75 1,000 0,05347239 0,09097008 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,05474357 0,09306788 ! regulation of blood pressure GO:0008217 134 76 1,000 0,05474357 0,09300316 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,05474357 0,09293853 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,05602538 0,09504862 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,05602538 0,09498266 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,05602538 0,09491679 ! antigen processing and presentation GO:0019882 117 78 1,000 0,05731769 0,09703889 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05783622 0,09784894 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05783622 0,09778123 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,05783622 0,09771361 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,05783622 0,09764608 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05783622 0,09757864 ! protein complex disassembly GO:0043241 28 12 0,000 0,05783622 0,0975113 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05783622 0,09744405 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05783622 0,0973769 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05783622 0,09730983 ! T cell proliferation GO:0042098 32 12 0,000 0,05783622 0,09724286 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05783622 0,09717598 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05783622 0,09710919 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05783622 0,0970425 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05783622 0,09697589 ! drug transport GO:0015893 16 12 0,000 0,05783622 0,09690938 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05783622 0,09684296 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05783622 0,09677663 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05783622 0,09671039 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05783622 0,09664424 ! focal adhesion formation GO:0048041 37 12 0,000 0,05783622 0,09657818 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05783622 0,09651221 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05783622 0,09644633 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05783622 0,09638054 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05783622 0,09631484 ! lipid digestion GO:0044241 21 12 0,000 0,05783622 0,09624923 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05783622 0,09618371 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05783622 0,09611828 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05783622 0,09605294 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05783622 0,09598769 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05783622 0,09592252 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05783622 0,09585745 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05783622 0,09579246 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05783622 0,09572756 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05783622 0,09566275 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05783622 0,09559802 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05783622 0,09553339 ! fucose catabolic process GO:0019317 25 12 0,000 0,05783622 0,09546884 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05783622 0,09540437 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05783622 0,09534 ! zymogen activation GO:0031638 18 12 0,000 0,05783622 0,09527571 ! T cell homeostasis GO:0043029 28 12 0,000 0,05783622 0,09521151 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05783622 0,09514739 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05783622 0,09508336 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,05783622 0,09501942 ! oocyte differentiation GO:0009994 21 12 0,000 0,05783622 0,09495556 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05783622 0,09489179 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05783622 0,0948281 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,05783622 0,0947645 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05783622 0,09470099 ! defense response to fungus GO:0050832 15 12 0,000 0,05783622 0,09463756 ! developmental induction GO:0031128 22 12 0,000 0,05783622 0,09457421 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05783622 0,09451095 ! response to cold GO:0009409 17 12 0,000 0,05783622 0,09444778 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05783622 0,09438469 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05783622 0,09432168 ! localization within membrane GO:0051668 26 12 0,000 0,05783622 0,09425876 ! blood coagulation GO:0007596 151 79 1,000 0,05862036 0,09547303 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,05862036 0,09540942 ! protein oligomerization GO:0051259 149 79 1,000 0,05862036 0,0953459 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,05993326 0,09741646 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,05993326 0,09735169 ! meiosis GO:0007126 143 81 1,000 0,06125625 0,09943456 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 1,000 0,06125625 0,09936854 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06250302 0,10132374 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06250302 0,10125655 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06250302 0,10118945 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06250302 0,10112243 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06250302 0,10105551 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06250302 0,10098867 ! peroxisomal transport GO:0043574 28 13 0,000 0,06250302 0,10092193 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06250302 0,10085527 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06250302 0,1007887 ! organelle fusion GO:0048284 36 13 0,000 0,06250302 0,10072221 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06250302 0,10065582 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06250302 0,10058951 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06250302 0,10052329 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06250302 0,10045715 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06250302 0,10039111 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06250302 0,10032515 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06250302 0,10025927 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06250302 0,10019349 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06250302 0,10012779 ! methionine metabolic process GO:0006555 31 13 0,000 0,06250302 0,10006217 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06250302 0,09999664 ! Golgi organization GO:0007030 25 13 0,000 0,06250302 0,0999312 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06250302 0,09986584 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06250302 0,09980057 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06250302 0,09973539 ! exocrine system development GO:0035272 34 13 0,000 0,06250302 0,09967028 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06250302 0,09960527 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06250302 0,09954034 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06250302 0,09947549 ! L-glutamate transport GO:0015813 30 13 0,000 0,06250302 0,09941073 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06250302 0,09934605 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06250302 0,09928145 ! protein homotetramerization GO:0051289 24 13 0,000 0,06250302 0,09921694 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06250302 0,09915252 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06250302 0,09908817 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06250302 0,09902391 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06250302 0,09895974 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06250302 0,09889564 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06250302 0,09883163 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,06250302 0,09876771 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06250302 0,09870386 ! histone methylation GO:0016571 29 13 0,000 0,06250302 0,0986401 ! chromatin silencing GO:0006342 29 13 0,000 0,06250302 0,09857642 ! gland morphogenesis GO:0022612 31 13 0,000 0,06250302 0,09851282 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06250302 0,09844931 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06250302 0,09838587 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06250302 0,09832252 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06250302 0,09825925 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06250302 0,09819606 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06250302 0,09813295 ! spleen development GO:0048536 24 13 0,000 0,06250302 0,09806993 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06250302 0,09800698 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06250302 0,09794411 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06250302 0,09788133 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06250302 0,09781863 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06250302 0,097756 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06250302 0,09769346 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06250302 0,09763099 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06250302 0,09756861 ! insulin secretion GO:0030073 24 13 0,000 0,06250302 0,09750631 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06250302 0,09744408 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06250302 0,09738194 ! acrosome reaction GO:0007340 19 13 0,000 0,06250302 0,09731987 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06250302 0,09725788 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06250302 0,09719597 ! meiotic cell cycle GO:0051321 144 82 1,000 0,06258921 0,09726809 ! response to drug GO:0042493 149 83 1,000 0,063932 0,09929172 ! response to oxygen levels GO:0070482 183 83 1,000 0,063932 0,09922864 ! T cell activation GO:0042110 189 84 1,000 0,0652845 0,10126351 ! hemostasis GO:0007599 165 85 1,000 0,06664658 0,10331065 ! negative regulation of transport GO:0051051 164 85 1,000 0,06664658 0,10324514 ! cholesterol metabolic process GO:0008203 148 85 1,000 0,06664658 0,10317971 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,06664658 0,10311437 ! rRNA transcription GO:0009303 28 14 0,000 0,06714684 0,10382261 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06714684 0,10375694 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06714684 0,10369135 ! water transport GO:0006833 21 14 0,000 0,06714684 0,10362585 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06714684 0,10356043 ! non-recombinational repair GO:0000726 29 14 0,000 0,06714684 0,10349509 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06714684 0,10342984 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06714684 0,10336466 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06714684 0,10329957 ! lipid localization GO:0010876 32 14 0,000 0,06714684 0,10323456 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06714684 0,10316964 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,06714684 0,10310479 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06714684 0,10304003 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06714684 0,10297534 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06714684 0,10291074 ! arginine metabolic process GO:0006525 21 14 0,000 0,06714684 0,10284622 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06714684 0,10278178 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06714684 0,10271742 ! regulation of heart rate GO:0002027 25 14 0,000 0,06714684 0,10265314 ! fear response GO:0042596 34 14 0,000 0,06714684 0,10258894 ! organic alcohol transport GO:0015850 29 14 0,000 0,06714684 0,10252483 ! embryo implantation GO:0007566 30 14 0,000 0,06714684 0,10246079 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06714684 0,10239683 ! bone mineralization GO:0030282 18 14 0,000 0,06714684 0,10233295 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06714684 0,10226915 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06714684 0,10220543 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06714684 0,10214179 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06714684 0,10207823 ! regulation of cellular pH GO:0030641 27 14 0,000 0,06714684 0,10201475 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06714684 0,10195135 ! ribosome assembly GO:0042255 18 14 0,000 0,06714684 0,10188803 ! cerebellum development GO:0021549 23 14 0,000 0,06714684 0,10182478 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06714684 0,10176161 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06714684 0,10169852 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06714684 0,10163551 ! response to gamma radiation GO:0010332 30 14 0,000 0,06714684 0,10157258 ! NADP metabolic process GO:0006739 24 14 0,000 0,06714684 0,10150973 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06714684 0,10144695 ! oxygen transport GO:0015671 22 14 0,000 0,06714684 0,10138425 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06714684 0,10132163 ! male genitalia development GO:0030539 26 14 0,000 0,06714684 0,10125909 ! regulation of RNA stability GO:0043487 33 14 0,000 0,06714684 0,10119662 ! regulation of axon extension GO:0030516 43 14 0,000 0,06714684 0,10113423 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06714684 0,10107192 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06714684 0,10100968 ! alcohol catabolic process GO:0046164 142 87 1,000 0,06939896 0,10433333 ! regulation of protein transport GO:0051223 165 87 1,000 0,06939896 0,10426916 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,07078902 0,1062923 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07176778 0,10769575 ! lactation GO:0007595 30 15 0,000 0,07176778 0,10762964 ! reproductive cellular process GO:0048610 22 15 0,000 0,07176778 0,10756361 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07176778 0,10749766 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07176778 0,10743179 ! superoxide anion generation GO:0042554 22 15 0,000 0,07176778 0,10736601 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07176778 0,1073003 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07176778 0,10723467 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07176778 0,10716912 ! copper ion transport GO:0006825 22 15 0,000 0,07176778 0,10710366 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07176778 0,10703827 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07176778 0,10697296 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07176778 0,10690774 ! sulfate transport GO:0008272 27 15 0,000 0,07176778 0,10684259 ! response to cAMP GO:0051591 25 15 0,000 0,07176778 0,10677752 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07176778 0,10671253 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07176778 0,10664762 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07176778 0,10658279 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07176778 0,10651804 ! vesicle coating GO:0006901 38 15 0,000 0,07176778 0,10645336 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07176778 0,10638877 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07176778 0,10632425 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07176778 0,10625981 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07176778 0,10619545 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07176778 0,10613117 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07176778 0,10606696 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07176778 0,10600283 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07176778 0,10593878 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07176778 0,10587481 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07176778 0,10581092 ! histone deacetylation GO:0016575 24 15 0,000 0,07176778 0,1057471 ! water homeostasis GO:0030104 28 15 0,000 0,07176778 0,10568336 ! cofactor transport GO:0051181 30 15 0,000 0,07176778 0,10561969 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07176778 0,1055561 ! muscle maintenance GO:0046716 26 15 0,000 0,07176778 0,10549259 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07176778 0,10542916 ! intestinal absorption GO:0050892 31 15 0,000 0,07176778 0,1053658 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07176778 0,10530252 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07176778 0,10523931 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07176778 0,10517618 ! cell killing GO:0001906 32 15 0,000 0,07176778 0,10511312 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,07176778 0,10505014 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07176778 0,10498724 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07176778 0,10492441 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07176778 0,10486166 ! actin filament polymerization GO:0030041 27 15 0,000 0,07176778 0,10479898 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07176778 0,10473637 ! oxidative phosphorylation GO:0006119 152 90 1,000 0,07359624 0,10734067 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,07359624 0,10727662 ! gland development GO:0048732 220 91 1,000 0,07501316 0,10927678 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07636596 0,1111812 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07636596 0,11111498 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07636596 0,11104884 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07636596 0,11098278 ! bone remodeling GO:0046849 28 16 0,000 0,07636596 0,1109168 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07636596 0,11085089 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07636596 0,11078507 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07636596 0,11071932 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07636596 0,11065365 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07636596 0,11058806 ! startle response GO:0001964 28 16 0,000 0,07636596 0,11052254 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07636596 0,11045711 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07636596 0,11039175 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07636596 0,11032646 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07636596 0,11026126 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07636596 0,11019613 ! pituitary gland development GO:0021983 30 16 0,000 0,07636596 0,11013108 ! response to osmotic stress GO:0006970 27 16 0,000 0,07636596 0,11006611 ! lysosomal transport GO:0007041 31 16 0,000 0,07636596 0,11000121 ! fructose metabolic process GO:0006000 25 16 0,000 0,07636596 0,10993639 ! L-amino acid transport GO:0015807 33 16 0,000 0,07636596 0,10987164 ! stem cell development GO:0048864 46 16 0,000 0,07636596 0,10980698 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07636596 0,10974238 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,07636596 0,10967787 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07636596 0,10961343 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07636596 0,10954906 ! axon cargo transport GO:0008088 46 16 0,000 0,07636596 0,10948477 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07636596 0,10942056 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,07636596 0,10935642 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,07636596 0,10929236 ! DNA replication initiation GO:0006270 28 16 0,000 0,07636596 0,10922837 ! neuron recognition GO:0008038 40 16 0,000 0,07636596 0,10916445 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07636596 0,10910061 ! tissue regeneration GO:0042246 27 16 0,000 0,07636596 0,10903685 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07636596 0,10897316 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07636596 0,10890954 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,07636596 0,108846 ! biomineral formation GO:0031214 22 16 0,000 0,07636596 0,10878254 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07636596 0,10871914 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07636596 0,10865582 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07636596 0,10859258 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07636596 0,10852941 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07636596 0,10846631 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07636596 0,10840328 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07636596 0,10834033 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07636596 0,10827745 ! peptide hormone processing GO:0016486 27 16 0,000 0,07636596 0,10821465 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,0764388 0,10825506 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,07787302 0,11022236 ! regulation of defense response GO:0031347 171 95 1,000 0,08076678 0,11425202 ! phospholipid biosynthetic process GO:0008654 188 95 1,000 0,08076678 0,1141859 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,0809415 0,11436673 ! metencephalon development GO:0022037 32 17 0,000 0,0809415 0,11430063 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,0809415 0,11423459 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,0809415 0,11416864 ! signal complex assembly GO:0007172 47 17 0,000 0,0809415 0,11410276 ! endothelial cell migration GO:0043542 31 17 0,000 0,0809415 0,11403696 ! gene silencing by RNA GO:0031047 38 17 0,000 0,0809415 0,11397123 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,0809415 0,11390558 ! glial cell development GO:0021782 28 17 0,000 0,0809415 0,11384 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,0809415 0,1137745 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,0809415 0,11370907 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,0809415 0,11364372 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,0809415 0,11357845 ! myoblast differentiation GO:0045445 50 17 0,000 0,0809415 0,11351325 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,0809415 0,11344812 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,0809415 0,11338307 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,0809415 0,1133181 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,0809415 0,1132532 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,0809415 0,11318837 ! NAD metabolic process GO:0019674 33 17 0,000 0,0809415 0,11312362 ! membrane budding GO:0006900 42 17 0,000 0,0809415 0,11305894 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,0809415 0,11299433 ! regulation of protein binding GO:0043393 33 17 0,000 0,0809415 0,1129298 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,0809415 0,11286534 ! genitalia development GO:0048806 32 17 0,000 0,0809415 0,11280096 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,0809415 0,11273665 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,0809415 0,11267241 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,0809415 0,11260825 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,0809415 0,11254416 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,0809415 0,11248014 ! steroid catabolic process GO:0006706 34 17 0,000 0,0809415 0,11241619 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,0809415 0,11235232 ! gas transport GO:0015669 26 17 0,000 0,0809415 0,11228852 ! organic cation transport GO:0015695 32 17 0,000 0,0809415 0,11222479 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,0809415 0,11216114 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,0809415 0,11209755 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,0809415 0,11203404 ! sex differentiation GO:0007548 171 96 1,000 0,08222607 0,11374762 ! regulation of T cell activation GO:0050863 175 96 1,000 0,08222607 0,11368325 ! transcription initiation GO:0006352 171 97 1,000 0,08369349 0,1156466 ! regulation of protein localization GO:0032880 188 97 1,000 0,08369349 0,11558123 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,08516891 0,11755235 ! forebrain development GO:0030900 210 98 1,000 0,08516891 0,11748597 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,08549449 0,11786854 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08549449 0,11780206 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08549449 0,11773565 ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08549449 0,11766932 ! adult walking behavior GO:0007628 36 18 0,000 0,08549449 0,11760307 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08549449 0,11753689 ! heart looping GO:0001947 34 18 0,000 0,08549449 0,11747078 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08549449 0,11740475 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,08549449 0,11733879 ! centrosome cycle GO:0007098 26 18 0,000 0,08549449 0,11727291 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,08549449 0,1172071 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08549449 0,11714136 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,08549449 0,1170757 ! glycine metabolic process GO:0006544 30 18 0,000 0,08549449 0,11701011 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08549449 0,1169446 ! response to retinoic acid GO:0032526 31 18 0,000 0,08549449 0,11687916 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,08549449 0,11681379 ! DNA integration GO:0015074 32 18 0,000 0,08549449 0,11674849 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,08549449 0,11668327 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08549449 0,11661812 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08549449 0,11655304 ! neural crest cell migration GO:0001755 41 18 0,000 0,08549449 0,11648804 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08549449 0,11642311 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08549449 0,11635825 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08549449 0,11629346 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08549449 0,11622874 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08549449 0,1161641 ! detection of bacterium GO:0016045 22 18 0,000 0,08549449 0,11609953 ! defense response to virus GO:0051607 43 18 0,000 0,08549449 0,11603503 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08549449 0,1159706 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09002506 0,12204841 ! positive regulation of translation GO:0045727 31 19 0,000 0,09002506 0,12198072 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09002506 0,1219131 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09002506 0,12184556 ! neuron maturation GO:0042551 46 19 0,000 0,09002506 0,12177809 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09002506 0,1217107 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09002506 0,12164338 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09002506 0,12157614 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09002506 0,12150897 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09002506 0,12144187 ! inositol metabolic process GO:0006020 33 19 0,000 0,09002506 0,12137485 ! memory GO:0007613 34 19 0,000 0,09002506 0,1213079 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09002506 0,12124103 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09002506 0,12117423 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09002506 0,12110751 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09002506 0,12104085 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09002506 0,12097427 ! pigmentation during development GO:0048066 42 19 0,000 0,09002506 0,12090777 ! response to vitamin A GO:0033189 32 19 0,000 0,09002506 0,12084133 ! heme metabolic process GO:0042168 40 19 0,000 0,09002506 0,12077497 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09002506 0,12070869 ! response to fungus GO:0009620 26 19 0,000 0,09002506 0,12064247 ! peptide cross-linking GO:0018149 39 19 0,000 0,09002506 0,12057633 ! heart process GO:0003015 32 19 0,000 0,09002506 0,12051026 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09002506 0,12044427 ! visual learning GO:0008542 38 19 0,000 0,09002506 0,12037834 ! cellular pigmentation GO:0033059 37 19 0,000 0,09002506 0,12031249 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09002506 0,12024671 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09002506 0,120181 ! vitamin transport GO:0051180 31 19 0,000 0,09002506 0,12011536 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09002506 0,1200498 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09002506 0,1199843 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09002506 0,11991888 ! cilium assembly GO:0042384 38 19 0,000 0,09002506 0,11985353 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09002506 0,11978825 ! protein secretion GO:0009306 45 20 0,000 0,09453331 0,1257185 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09453331 0,1256501 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,09453331 0,12558178 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09453331 0,12551352 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09453331 0,12544535 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09453331 0,12537724 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,09453331 0,12530922 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09453331 0,12524126 ! response to vitamin GO:0033273 36 20 0,000 0,09453331 0,12517338 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,09453331 0,12510557 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09453331 0,12503784 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09453331 0,12497018 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,09453331 0,12490259 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09453331 0,12483507 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09453331 0,12476763 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,09453331 0,12470026 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,09453331 0,12463297 ! actin filament bundle formation GO:0051017 47 20 0,000 0,09453331 0,12456574 ! body fluid secretion GO:0007589 33 20 0,000 0,09453331 0,12449859 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,09453331 0,12443151 ! peptide secretion GO:0002790 38 20 0,000 0,09453331 0,1243645 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09453331 0,12429757 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09453331 0,12423071 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09453331 0,12416392 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09453331 0,1240972 ! cell-cell junction organization GO:0045216 43 20 0,000 0,09453331 0,12403055 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,09453331 0,12396397 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09453331 0,12389747 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09453331 0,12383104 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09453331 0,12376468 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09453331 0,12369838 ! regulation of glucose import GO:0046324 30 20 0,000 0,09453331 0,12363217 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09453331 0,12356602 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09453331 0,12349994 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09453331 0,12343393 ! regulation of cell killing GO:0031341 46 21 0,000 0,09901935 0,12922237 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,09901935 0,12915338 ! hormone secretion GO:0046879 39 21 0,000 0,09901935 0,12908446 ! cAMP metabolic process GO:0046058 41 21 0,000 0,09901935 0,12901562 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,09901935 0,12894685 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,09901935 0,12887815 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,09901935 0,12880952 ! smooth muscle contraction GO:0006939 48 21 0,000 0,09901935 0,12874097 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,09901935 0,12867249 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,09901935 0,12860409 ! plasma membrane fusion GO:0045026 33 21 0,000 0,09901935 0,12853575 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,09901935 0,12846749 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,09901935 0,1283993 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,09901935 0,12833119 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,09901935 0,12826314 ! diencephalon development GO:0021536 36 21 0,000 0,09901935 0,12819517 ! collagen fibril organization GO:0030199 62 21 0,000 0,09901935 0,12812727 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,09901935 0,12805944 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,09901935 0,12799168 ! collagen catabolic process GO:0030574 29 21 0,000 0,09901935 0,127924 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,09901935 0,12785639 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,09901935 0,12778885 ! sperm-egg recognition GO:0035036 23 21 0,000 0,09901935 0,12772137 ! actin filament-based movement GO:0030048 47 21 0,000 0,09901935 0,12765398 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,09901935 0,12758665 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,1034833 0,13326816 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,1034833 0,13319794 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,1034833 0,1331278 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,1034833 0,13305773 ! microtubule-based transport GO:0010970 59 22 0,000 0,1034833 0,13298774 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,1034833 0,13291782 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,1034833 0,13284797 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,1034833 0,1327782 ! cellular response to starvation GO:0009267 37 22 0,000 0,1034833 0,1327085 ! vacuolar transport GO:0007034 41 22 0,000 0,1034833 0,13263887 ! central nervous system neuron development GO:0021954 47 22 0,000 0,1034833 0,13256932 ! fucose metabolic process GO:0006004 44 22 0,000 0,1034833 0,13249984 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,1034833 0,13243043 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,1034833 0,1323611 ! stem cell differentiation GO:0048863 57 22 0,000 0,1034833 0,13229183 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,1034833 0,13222264 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,1034833 0,13215352 ! cytolysis GO:0019835 27 22 0,000 0,1034833 0,13208448 ! vasodilation GO:0042311 40 22 0,000 0,1034833 0,13201551 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,1034833 0,1319466 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,1034833 0,13187777 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,1034833 0,13180902 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,1034833 0,13174033 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,1034833 0,13167172 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,1034833 0,13160317 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,1034833 0,1315347 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,1034833 0,1314663 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,1034833 0,13139797 ! sarcomere organization GO:0045214 32 22 0,000 0,1034833 0,13132971 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,1034833 0,13126152 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,1034833 0,13119341 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,1034833 0,13112536 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,1034833 0,13105738 ! gut development GO:0048565 44 22 0,000 0,1034833 0,13098948 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,1034833 0,13092164 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,1034833 0,13085388 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,10792525 0,13640009 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10792525 0,13632956 ! gluconeogenesis GO:0006094 38 23 0,000 0,10792525 0,13625911 ! glycerol metabolic process GO:0006071 40 23 0,000 0,10792525 0,13618873 ! viral genome replication GO:0019079 44 23 0,000 0,10792525 0,13611842 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,10792525 0,13604818 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10792525 0,13597802 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,10792525 0,13590793 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10792525 0,13583791 ! regeneration GO:0031099 42 23 0,000 0,10792525 0,13576796 ! axis specification GO:0009798 43 23 0,000 0,10792525 0,13569808 ! visual behavior GO:0007632 46 23 0,000 0,10792525 0,13562828 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,10792525 0,13555855 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,10792525 0,13548889 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10792525 0,1354193 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10792525 0,13534978 ! peroxisome organization GO:0007031 43 23 0,000 0,10792525 0,13528034 ! lysosome organization GO:0007040 47 23 0,000 0,10792525 0,13521096 ! vesicle targeting GO:0006903 49 23 0,000 0,10792525 0,13514166 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,10792525 0,13507243 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10792525 0,13500326 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10792525 0,13493417 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10792525 0,13486515 ! fatty acid transport GO:0015908 47 23 0,000 0,10792525 0,1347962 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,10792525 0,13472733 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,10792525 0,13465852 ! hormone transport GO:0009914 41 23 0,000 0,10792525 0,13458978 ! cell-cell recognition GO:0009988 28 23 0,000 0,10792525 0,13452111 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10792525 0,13445251 ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,10792525 0,13438398 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11234531 0,1398164 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11234531 0,13974521 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11234531 0,1396741 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11234531 0,13960305 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11234531 0,13953208 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,11234531 0,13946118 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11234531 0,13939035 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11234531 0,13931959 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11234531 0,13924891 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,11234531 0,13917829 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11234531 0,13910775 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,11234531 0,13903728 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11234531 0,13896688 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,11234531 0,13889656 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11234531 0,1388263 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11234531 0,13875612 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11234531 0,138686 ! membrane depolarization GO:0051899 45 24 0,000 0,11234531 0,13861596 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11234531 0,13854599 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11234531 0,13847608 ! platelet activation GO:0030168 41 24 0,000 0,11234531 0,13840625 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,11234531 0,13833649 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11234531 0,1382668 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11234531 0,13819718 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11234531 0,13812763 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,11234531 0,13805815 ! regulation of amine transport GO:0051952 41 24 0,000 0,11234531 0,13798874 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,1167436 0,1433189 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,1167436 0,14324692 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,1167436 0,14317501 ! leukocyte adhesion GO:0007159 55 25 0,000 0,1167436 0,14310317 ! phototransduction GO:0007602 37 25 0,000 0,1167436 0,1430314 ! keratinization GO:0031424 37 25 0,000 0,1167436 0,14295971 ! vasculogenesis GO:0001570 49 25 0,000 0,1167436 0,14288808 ! vacuole organization GO:0007033 49 25 0,000 0,1167436 0,14281653 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,1167436 0,14274505 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,1167436 0,14267365 ! receptor metabolic process GO:0043112 53 25 0,000 0,1167436 0,14260231 ! chromosome condensation GO:0030261 48 25 0,000 0,1167436 0,14253104 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,1167436 0,14245985 ! regulation of behavior GO:0050795 48 25 0,000 0,1167436 0,14238873 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,1167436 0,14231767 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,1167436 0,14224669 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,1167436 0,14217578 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,1167436 0,14210494 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,1167436 0,14203417 ! liver development GO:0001889 55 25 0,000 0,1167436 0,14196347 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12112022 0,14721229 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12112022 0,14713908 ! molting cycle process GO:0022404 52 26 0,000 0,12112022 0,14706595 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12112022 0,14699289 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12112022 0,14691991 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,12112022 0,146847 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12112022 0,14677416 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12112022 0,14670139 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12112022 0,14662869 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12112022 0,14655607 ! digestive system process GO:0022600 49 26 0,000 0,12112022 0,14648351 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12112022 0,14641103 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12112022 0,14633862 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,12112022 0,14626629 ! neural crest cell development GO:0014032 59 26 0,000 0,12112022 0,14619402 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 83 26 0,000 0,12112022 0,14612183 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12112022 0,1460497 ! pentose metabolic process GO:0019321 43 26 0,000 0,12112022 0,14597765 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12112022 0,14590567 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12112022 0,14583376 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12112022 0,14576192 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,12112022 0,14569015 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 50 26 0,000 0,12112022 0,14561845 ! telomere organization GO:0032200 46 26 0,000 0,12112022 0,14554683 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12112022 0,14547527 ! neural tube closure GO:0001843 58 26 0,000 0,12112022 0,14540378 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,12112022 0,14533237 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,12112022 0,14526102 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12112022 0,14518974 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,12547527 0,15033649 ! embryonic pattern specification GO:0009880 49 27 0,000 0,12547527 0,15026279 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,12547527 0,15018917 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,12547527 0,15011562 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,12547527 0,15004214 ! iron ion transport GO:0006826 65 27 0,000 0,12547527 0,14996874 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,12547527 0,1498954 ! superoxide metabolic process GO:0006801 41 27 0,000 0,12547527 0,14982214 ! tube lumen formation GO:0035148 59 27 0,000 0,12547527 0,14974895 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,12547527 0,14967583 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,12547527 0,14960278 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,12547527 0,1495298 ! response to starvation GO:0042594 47 27 0,000 0,12547527 0,1494569 ! response to toxin GO:0009636 49 27 0,000 0,12547527 0,14938406 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,12547527 0,1493113 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,12547527 0,14923861 ! leukocyte proliferation GO:0070661 59 27 0,000 0,12547527 0,14916598 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,12980887 0,15424274 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,12980887 0,15416776 ! vesicle docking GO:0048278 55 28 0,000 0,12980887 0,15409284 ! circadian rhythm GO:0007623 56 28 0,000 0,12980887 0,15401801 ! fat cell differentiation GO:0045444 57 28 0,000 0,12980887 0,15394324 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,12980887 0,15386855 ! sperm motility GO:0030317 37 28 0,000 0,12980887 0,15379392 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,12980887 0,15371938 ! base-excision repair GO:0006284 41 28 0,000 0,12980887 0,1536449 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,12980887 0,1535705 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,12980887 0,15349616 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,12980887 0,1534219 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,12980887 0,15334771 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,12980887 0,1532736 ! glutathione metabolic process GO:0006749 42 28 0,000 0,12980887 0,15319955 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,12980887 0,15312558 ! lipid oxidation GO:0034440 48 28 0,000 0,12980887 0,15305168 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,12980887 0,15297785 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,12980887 0,15290409 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,13412111 0,15790741 ! translational initiation GO:0006413 66 29 0,000 0,13412111 0,15783135 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,13412111 0,15775536 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,13412111 0,15767944 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,13412111 0,1576036 ! autophagy GO:0006914 47 29 0,000 0,13412111 0,15752783 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,13412111 0,15745213 ! primary neural tube formation GO:0014020 61 29 0,000 0,13412111 0,15737651 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,13412111 0,15730095 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,13412111 0,15722547 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,13412111 0,15715006 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,13412111 0,15707473 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,13412111 0,15699947 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,13412111 0,15692427 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,13412111 0,15684915 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,13841211 0,16178985 ! phenol metabolic process GO:0018958 56 30 0,000 0,13841211 0,16171247 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,13841211 0,16163517 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,13841211 0,16155795 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,13841211 0,16148079 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,13841211 0,16140372 ! acute-phase response GO:0006953 50 30 0,000 0,13841211 0,16132671 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,13841211 0,16124978 ! myofibril assembly GO:0030239 50 30 0,000 0,13841211 0,16117292 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,13841211 0,16109613 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,13841211 0,16101942 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,13841211 0,16094278 ! cell fate determination GO:0001709 64 30 0,000 0,13841211 0,16086622 ! phospholipid transport GO:0015914 65 30 0,000 0,13841211 0,16078972 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,13841211 0,1607133 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,13841211 0,16063695 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,13841211 0,16056068 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 0,000 0,13841211 0,16048447 ! regulation of coagulation GO:0050818 52 30 0,000 0,13841211 0,16040834 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,14268196 0,16527834 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,14268196 0,16520001 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,14268196 0,16512176 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,14268196 0,16504357 ! cell junction assembly GO:0034329 85 31 0,000 0,14268196 0,16496547 ! regulation of innate immune response GO:0045088 57 31 0,000 0,14268196 0,16488743 ! peptide transport GO:0015833 60 31 0,000 0,14268196 0,16480947 ! male gonad development GO:0008584 56 31 0,000 0,14268196 0,16473158 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,14268196 0,16465377 ! detection of light stimulus GO:0009583 44 31 0,000 0,14268196 0,16457603 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,14268196 0,16449836 ! natural killer cell activation GO:0030101 50 31 0,000 0,14268196 0,16442077 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,14268196 0,16434325 ! eye morphogenesis GO:0048592 65 31 0,000 0,14268196 0,1642658 ! response to heat GO:0009408 54 31 0,000 0,14268196 0,16418843 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,14268196 0,16411112 ! collagen metabolic process GO:0032963 49 32 0,000 0,14693077 0,16891853 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,14693077 0,16883907 ! spindle organization GO:0007051 50 32 0,000 0,14693077 0,16875969 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,14693077 0,16868039 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,14693077 0,16860116 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,14693077 0,168522 ! muscle cell development GO:0055001 52 32 0,000 0,14693077 0,16844292 ! mesoderm formation GO:0001707 73 32 0,000 0,14693077 0,16836392 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,14693077 0,16828498 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,14693077 0,16820612 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,14693077 0,16812734 ! gene silencing GO:0016458 71 32 0,000 0,14693077 0,16804863 ! regulation of pH GO:0006885 56 33 0,000 0,15115864 0,17280326 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15115864 0,17272243 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,15115864 0,17264168 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15115864 0,17256101 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,15115864 0,17248041 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15115864 0,17239989 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,15115864 0,17231944 ! response to ionizing radiation GO:0010212 74 33 0,000 0,15115864 0,17223907 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,15115864 0,17215877 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,15115864 0,17207855 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15115864 0,1719984 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15115864 0,17191832 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15115864 0,17183833 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,15536568 0,17653877 ! glial cell differentiation GO:0010001 67 34 0,000 0,15536568 0,1764567 ! post-embryonic development GO:0009791 76 34 0,000 0,15536568 0,1763747 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,15536568 0,17629278 ! cholesterol transport GO:0030301 62 34 0,000 0,15536568 0,17621093 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,15536568 0,17612917 ! spliceosome assembly GO:0000245 75 34 0,000 0,15536568 0,17604747 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,15536568 0,17596586 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,15536568 0,17588432 ! formation of primary germ layer GO:0001704 76 34 0,000 0,15536568 0,17580285 ! cell fate specification GO:0001708 56 34 0,000 0,15536568 0,17572146 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,15536568 0,17564014 ! adult locomotory behavior GO:0008344 62 34 0,000 0,15536568 0,1755589 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,15955198 0,18020596 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,15955198 0,18012269 ! negative regulation of secretion GO:0051048 68 35 0,000 0,15955198 0,18003949 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,15955198 0,17995637 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,15955198 0,17987332 ! membrane docking GO:0022406 69 35 0,000 0,15955198 0,17979036 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,15955198 0,17970747 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,15955198 0,17962465 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,15955198 0,17954191 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,15955198 0,17945925 ! ceramide metabolic process GO:0006672 72 35 0,000 0,15955198 0,17937666 ! sterol transport GO:0015918 63 35 0,000 0,15955198 0,17929415 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,15955198 0,17921172 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,15955198 0,17912936 ! placenta development GO:0001890 53 35 0,000 0,15955198 0,17904708 ! vesicle localization GO:0051648 70 35 0,000 0,15955198 0,17896487 ! regulation of muscle development GO:0048634 82 36 0,000 0,16371765 0,18355311 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,16371765 0,18346891 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,16371765 0,18338479 ! protein targeting to membrane GO:0006612 75 36 0,000 0,16371765 0,18330075 ! regulation of proteolysis GO:0030162 77 36 0,000 0,16371765 0,18321678 ! cytokine production GO:0001816 68 36 0,000 0,16371765 0,18313289 ! embryonic organ development GO:0048568 67 36 0,000 0,16371765 0,18304907 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,16371765 0,18296534 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,1678628 0,18751203 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,1678628 0,18742633 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,1678628 0,18734071 ! sister chromatid segregation GO:0000819 65 37 0,000 0,1678628 0,18725516 ! actomyosin structure organization GO:0031032 68 37 0,000 0,1678628 0,1871697 ! cell junction organization GO:0034330 96 37 0,000 0,1678628 0,18708431 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,1678628 0,186999 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,1678628 0,18691377 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,17198751 0,19141935 ! organic anion transport GO:0015711 82 38 0,000 0,17198751 0,19133219 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,17198751 0,1912451 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,17198751 0,19115809 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,17198751 0,19107116 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,17198751 0,19098431 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,17198751 0,19089754 ! spermatid development GO:0007286 69 38 0,000 0,17198751 0,19081085 ! glycogen metabolic process GO:0005977 63 38 0,000 0,17198751 0,19072423 ! pigment metabolic process GO:0042440 87 38 0,000 0,17198751 0,1906377 ! neural tube formation GO:0001841 79 38 0,000 0,17198751 0,19055124 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,17609189 0,19501019 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,17609189 0,19492183 ! negative regulation of binding GO:0051100 71 39 0,000 0,17609189 0,19483355 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,17609189 0,19474535 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,17609189 0,19465723 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,17609189 0,19456919 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,17609189 0,19448123 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,17609189 0,19439335 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,17609189 0,19430555 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,17609189 0,19421783 ! glucan metabolic process GO:0044042 64 39 0,000 0,17609189 0,19413018 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,18017604 0,19854311 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,18017604 0,19845359 ! learning GO:0007612 82 40 0,000 0,18017604 0,19836416 ! lipid homeostasis GO:0055088 75 40 0,000 0,18017604 0,19827481 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,18017604 0,19818553 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,18017604 0,19809634 ! RNA export from nucleus GO:0006405 61 41 0,000 0,18424006 0,20247345 ! mRNA catabolic process GO:0006402 79 41 0,000 0,18424006 0,20238241 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,18424006 0,20229145 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,18424006 0,20220057 ! gliogenesis GO:0042063 91 41 0,000 0,18424006 0,20210978 ! feeding behavior GO:0007631 69 41 0,000 0,18424006 0,20201906 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,18424006 0,20192843 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,18424006 0,20183788 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,18424006 0,20174741 ! spermatid differentiation GO:0048515 73 41 0,000 0,18424006 0,20165702 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,18424006 0,20156672 ! RNA modification GO:0009451 64 41 0,000 0,18424006 0,20147649 ! organic ether metabolic process GO:0018904 59 42 0,000 0,18828405 0,20580669 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,18828405 0,20571464 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,18828405 0,20562268 ! regulation of protein secretion GO:0050708 77 42 0,000 0,18828405 0,2055308 ! cytokinesis GO:0000910 84 42 0,000 0,18828405 0,20543901 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,18828405 0,2053473 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,19230811 0,20964244 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,19230811 0,20954893 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,19230811 0,20945551 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,19230811 0,20936217 ! glucose transport GO:0015758 66 43 0,000 0,19230811 0,20926891 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,19230811 0,20917574 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,19230811 0,20908265 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,19230811 0,20898964 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,19230811 0,20889671 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,19230811 0,20880387 ! ion transmembrane transport GO:0034220 79 43 0,000 0,19230811 0,20871111 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,19230811 0,20861843 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,19631233 0,21286774 ! hexose transport GO:0008645 68 44 0,000 0,19631233 0,2127733 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,19631233 0,21267894 ! phagocytosis GO:0006909 105 44 0,000 0,19631233 0,21258467 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,19631233 0,21249048 ! double-strand break repair GO:0006302 85 44 0,000 0,19631233 0,21239638 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,20029681 0,21661138 ! B cell differentiation GO:0030183 124 45 0,000 0,20029681 0,21651553 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,20029681 0,21641977 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,20029681 0,21632409 ! polyol metabolic process GO:0019751 77 45 0,000 0,20029681 0,2162285 ! maintenance of location in cell GO:0051651 101 45 0,000 0,20029681 0,21613299 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,20426164 0,22031399 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,20426164 0,22021677 ! leukocyte migration GO:0050900 75 46 0,000 0,20426164 0,22011963 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,20426164 0,22002257 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,20426164 0,2199256 ! cell growth GO:0016049 90 46 0,000 0,20426164 0,21982872 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,20426164 0,21973192 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,20820694 0,22387744 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,21213278 0,2279984 ! mitochondrial transport GO:0006839 94 48 0,000 0,21213278 0,22789814 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,21213278 0,22779797 ! endosome transport GO:0016197 127 48 0,000 0,21213278 0,22769788 ! male sex differentiation GO:0046661 93 48 0,000 0,21213278 0,22759788 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,21213278 0,22749797 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,21213278 0,22739815 ! response to calcium ion GO:0051592 94 49 0,000 0,21603926 0,23148417 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,21603926 0,23138269 ! protein homooligomerization GO:0051260 84 49 0,000 0,21603926 0,2312813 ! regulation of ion transport GO:0043269 86 50 0,000 0,21992649 0,23533965 ! endocrine system development GO:0035270 109 50 0,000 0,21992649 0,23523661 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,21992649 0,23513366 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,21992649 0,2350308 ! peptide metabolic process GO:0006518 80 51 0,000 0,22379455 0,23905994 ! response to temperature stimulus GO:0009266 84 51 0,000 0,22379455 0,23895546 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,22764354 0,24295901 ! Notch signaling pathway GO:0007219 111 52 0,000 0,22764354 0,24285291 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,22764354 0,24274691 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,22764354 0,242641 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,22764354 0,24253518 ! excretion GO:0007588 87 52 0,000 0,22764354 0,24242945 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,22764354 0,24232382 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,22764354 0,24221828 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,22764354 0,24211283 ! amino acid activation GO:0043038 98 52 0,000 0,22764354 0,24200747 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! inner ear development GO:0048839 89 53 0,000 0,23147355 0,24597211 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,23147355 0,24586516 ! vesicle organization GO:0016050 127 53 0,000 0,23147355 0,24575831 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,23147355 0,24565155 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,23528467 0,24958769 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,23528467 0,24947937 ! membrane fusion GO:0006944 122 54 0,000 0,23528467 0,24937113 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,23528467 0,24926299 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,23528467 0,24915495 ! RNA catabolic process GO:0006401 103 55 0,000 0,23907701 0,25306115 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,23907701 0,25295155 ! cell recognition GO:0008037 98 55 0,000 0,23907701 0,25284205 ! cell maturation GO:0048469 107 55 0,000 0,23907701 0,25273264 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,23907701 0,25262333 ! RNA elongation GO:0006354 90 56 0,000 0,24285064 0,25649983 ! chloride transport GO:0006821 102 57 0,000 0,24660566 0,26035334 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,24660566 0,26024088 ! regulation of actin filament length GO:0030832 118 58 0,000 0,25034217 0,26406991 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,25034217 0,26395594 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,25034217 0,26384207 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,25034217 0,2637283 ! gastrulation GO:0007369 122 58 0,000 0,25034217 0,26361462 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,25034217 0,26350104 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,25034217 0,26338756 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,25775999 0,27107519 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,25775999 0,27095855 ! adult behavior GO:0030534 104 60 0,000 0,25775999 0,27084201 ! positive regulation of secretion GO:0051047 110 61 0,000 0,26144149 0,27459224 ! regulation of cellular component size GO:0032535 125 61 0,000 0,26144149 0,27447424 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,26144149 0,27435634 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,26144149 0,27423854 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,26144149 0,27412084 ! regulation of heart contraction GO:0008016 123 61 0,000 0,26144149 0,27400324 ! proton transport GO:0015992 117 61 0,000 0,26144149 0,27388575 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,26144149 0,27376835 ! tRNA processing GO:0008033 102 62 0,000 0,26510483 0,27748548 ! regulation of mitosis GO:0007088 112 63 0,000 0,2687501 0,28118051 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,2687501 0,28106015 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,2687501 0,28093988 ! hydrogen transport GO:0006818 121 64 0,000 0,2723774 0,28460991 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,2723774 0,28448823 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,2759868 0,28813493 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,2795784 0,29175994 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,28315228 0,29536337 ! chromosome segregation GO:0007059 127 67 0,000 0,28315228 0,29523731 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,28315228 0,29511135 ! secondary metabolic process GO:0019748 125 67 0,000 0,28315228 0,29498551 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,28670853 0,29856306 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,28670853 0,29843585 ! extracellular matrix organization GO:0030198 146 68 0,000 0,28670853 0,29830875 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,28670853 0,29818176 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,28670853 0,29805487 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,28670853 0,29792809 ! negative regulation of cell size GO:0045792 144 69 0,000 0,29024724 0,30147705 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,29024724 0,30134892 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,29024724 0,30122091 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,29024724 0,301093 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,29024724 0,3009652 ! developmental maturation GO:0021700 128 69 0,000 0,29024724 0,30083751 ! single fertilization GO:0007338 83 69 0,000 0,29024724 0,30070993 ! cell redox homeostasis GO:0045454 114 70 0,000 0,2937685 0,3042291 ! germ cell development GO:0007281 133 70 0,000 0,2937685 0,30410018 ! activation of immune response GO:0002253 120 70 0,000 0,2937685 0,30397138 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,2937685 0,30384269 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,29727238 0,30733662 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,29727238 0,30720661 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,29727238 0,30707671 ! carbohydrate transport GO:0008643 114 72 0,000 0,30075898 0,31054699 ! actin filament organization GO:0007015 167 72 0,000 0,30075898 0,31041579 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,30075898 0,3102847 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,30075898 0,31015373 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,30075898 0,31002286 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,30075898 0,3098921 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,30075898 0,30976146 ! humoral immune response GO:0006959 115 73 0,000 0,30422837 0,31320266 ! regulation of immune effector process GO:0002697 156 73 0,000 0,30422837 0,31307073 ! acute inflammatory response GO:0002526 118 74 0,000 0,30768065 0,31649003 ! amino acid transport GO:0006865 148 74 0,000 0,30768065 0,31635683 ! transition metal ion transport GO:0000041 143 75 0,000 0,3111159 0,31975437 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,3145342 0,32313164 ! learning or memory GO:0007611 161 76 0,000 0,3145342 0,32299581 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,3145342 0,3228601 ! amine catabolic process GO:0009310 136 77 0,000 0,31793563 0,32621451 ! neurotransmitter transport GO:0006836 142 77 0,000 0,31793563 0,32607756 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,31793563 0,32594072 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,31793563 0,325804 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,32132028 0,32913435 ! fertilization GO:0009566 99 78 0,000 0,32132028 0,32899641 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,32132028 0,32885858 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,32468822 0,33216639 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,32468822 0,33202735 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,32468822 0,33188842 ! muscle cell differentiation GO:0042692 178 81 0,000 0,33137434 0,33858115 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,33137434 0,3384396 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,33469268 0,34168584 ! protein import into nucleus GO:0006606 174 82 0,000 0,33469268 0,34154311 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,33799464 0,34476864 ! exocytosis GO:0006887 153 83 0,000 0,33799464 0,34462475 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,33799464 0,34448098 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,33799464 0,34433732 ! nuclear import GO:0051170 177 83 0,000 0,33799464 0,34419379 ! inorganic anion transport GO:0015698 156 83 0,000 0,33799464 0,34405038 ! response to metal ion GO:0010038 158 84 0,000 0,3412803 0,34725022 ! response to nutrient GO:0007584 135 84 0,000 0,3412803 0,34710565 ! digestion GO:0007586 130 84 0,000 0,3412803 0,34696121 ! regulation of ligase activity GO:0051340 147 84 0,000 0,3412803 0,34681688 ! negative regulation of growth GO:0045926 168 85 0,000 0,34454975 0,34999378 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,34454975 0,34984831 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,34454975 0,34970297 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,34780307 0,35285834 ! regulation of lyase activity GO:0051339 169 86 0,000 0,34780307 0,35271187 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,34780307 0,35256551 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,35104032 0,35569951 ! nucleosome assembly GO:0006334 126 87 0,000 0,35104032 0,35555204 ! amine biosynthetic process GO:0009309 146 88 0,000 0,3542616 0,35866602 ! sensory perception of smell GO:0007608 117 88 0,000 0,3542616 0,35851744 ! chromatin assembly GO:0031497 128 88 0,000 0,3542616 0,35836898 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,35746698 0,36146185 ! cellular defense response GO:0006968 123 89 0,000 0,35746698 0,3613123 ! protein localization in nucleus GO:0034504 192 89 0,000 0,35746698 0,36116288 ! regulation of neurological system process GO:0031644 175 89 0,000 0,35746698 0,36101358 ! response to inorganic substance GO:0010035 173 90 0,000 0,36065654 0,36408427 ! response to unfolded protein GO:0006986 139 90 0,000 0,36065654 0,36393388 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,36383036 0,36698496 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,36383036 0,3668335 ! defense response to bacterium GO:0042742 112 91 0,000 0,36383036 0,36668216 ! bone development GO:0060348 206 92 0,000 0,36698851 0,36971254 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,36698851 0,36956015 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,37013107 0,37257115 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,37013107 0,37241771 ! vitamin metabolic process GO:0006766 153 93 0,000 0,37013107 0,37226439 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,37325811 0,37525497 ! female pregnancy GO:0007565 166 94 0,000 0,37325811 0,3751006 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,37325811 0,37494637 ! nucleosome organization GO:0034728 143 95 0,000 0,37636972 0,37791666 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,37636972 0,37776139 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,37636972 0,37760626 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,37636972 0,37745124 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,37636972 0,37729636 ! response to protein stimulus GO:0051789 158 96 0,000 0,37946597 0,3802442 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,38254693 0,38317432 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,38561269 0,3860868 ! mRNA transport GO:0051028 185 100 0,000 0,39169886 0,39201979 ! positive regulation of immune response GO:0050778 175 100 0,000 0,39169886 0,39185926 ! hormone metabolic process GO:0042445 171 100 0,000 0,39169886 0,39169886