pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6110-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! amyloid precursor protein catabolic process GO:0042987 5 5 3,000 8,705E-09 1,604E-05 ! amyloid precursor protein metabolic process GO:0042982 7 7 3,000 6,034E-08 5,56E-05 ! membrane protein ectodomain proteolysis GO:0006509 7 7 3,000 6,034E-08 3,707E-05 GO:0033619|membrane protein proteolysis, ! glycoprotein catabolic process GO:0006516 13 12 3,000 8,327E-07 3,837E-04 ! Notch signaling pathway GO:0007219 22 21 3,000 9,635E-06 3,551E-03 ! protein maturation GO:0051604 51 51 4,000 1,996E-05 6,132E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 3,185E-05 8,386E-03 ! cellular response to starvation GO:0009267 11 11 2,000 4,446E-05 0,01024345 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 4,446E-05 9,105E-03 ! protein maturation by peptide bond cleavage GO:0051605 32 32 3,000 5,486E-05 0,01011029 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 7,635E-05 0,01279233 ! protein tetramerization GO:0051262 13 13 2,000 7,635E-05 0,01172631 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 9,672E-05 0,01371188 ! response to starvation GO:0042594 15 15 2,000 1,203E-04 0,01584111 ! protein oligomerization GO:0051259 39 39 3,000 1,213E-04 0,01489851 ! cellular response to nutrient levels GO:0031669 16 16 2,000 1,474E-04 0,01697984 ! positive regulation of catabolic process GO:0009896 16 16 2,000 1,474E-04 0,01598103 ! negative regulation of cell development GO:0010721 18 17 2,000 1,782E-04 0,01824173 GO:0050768|negative regulation of neurogenesis, ! regulation of cell projection organization GO:0031344 19 18 2,000 2,128E-04 0,02064099 ! meiosis I GO:0007127 18 18 2,000 2,128E-04 0,01960894 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 2,128E-04 0,01867518 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 2,000 2,128E-04 0,01782631 ! protein processing GO:0016485 45 45 3,000 2,133E-04 0,01709288 ! regulation of catabolic process GO:0009894 48 47 3,000 2,529E-04 0,01941918 ! heart development GO:0007507 90 87 4,000 2,625E-04 0,01935425 ! positive regulation of transferase activity GO:0051347 91 88 4,000 2,77E-04 0,01963309 GO:0033674|positive regulation of kinase activity, ! leukocyte differentiation GO:0002521 50 49 3,000 2,975E-04 0,02030544 ! skeletal muscle tissue development GO:0007519 50 49 3,000 2,975E-04 0,01958025 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 2,975E-04 0,01890507 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 3,218E-04 0,01976735 ! T cell activation GO:0042110 51 50 3,000 3,218E-04 0,01912969 ! negative regulation of hydrolase activity GO:0051346 21 21 2,000 3,42E-04 0,01969659 ! negative regulation of protein transport GO:0051224 21 21 2,000 3,42E-04 0,01909972 ! response to light stimulus GO:0009416 53 52 3,000 3,746E-04 0,02030432 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 3,941E-04 0,0207543 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 4,318E-04 0,02210616 ! filopodium assembly GO:0046847 7 5 1,000 4,318E-04 0,0215087 GO:0030035|microspike assembly, ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 4,318E-04 0,02094268 ! tyrosine metabolic process GO:0006570 5 5 1,000 4,318E-04 0,02040569 ! vesicle fusion GO:0006906 5 5 1,000 4,318E-04 0,01989555 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,318E-04 0,01941029 ! receptor clustering GO:0043113 5 5 1,000 4,318E-04 0,01894814 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 4,318E-04 0,01850749 ! cellular glucose homeostasis GO:0001678 5 5 1,000 4,318E-04 0,01808686 ! protein heterooligomerization GO:0051291 5 5 1,000 4,318E-04 0,01768493 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 1,000 4,318E-04 0,01730048 ! decidualization GO:0046697 5 5 1,000 4,318E-04 0,01693238 ! T cell lineage commitment GO:0002360 5 5 1,000 4,318E-04 0,01657962 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 1,000 4,318E-04 0,01624126 ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,318E-04 0,01591644 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 4,318E-04 0,01560435 ! musculoskeletal movement GO:0050881 5 5 1,000 4,318E-04 0,01530427 GO:0050879|multicellular organismal movement, ! blastocyst formation GO:0001825 5 5 1,000 4,318E-04 0,01501551 ! nucleus localization GO:0051647 5 5 1,000 4,318E-04 0,01473744 ! cell projection assembly GO:0030031 25 23 2,000 4,511E-04 0,01511742 ! ectoderm development GO:0007398 99 99 4,000 4,788E-04 0,01575652 ! hemopoiesis GO:0030097 104 100 4,000 5,015E-04 0,01621406 ! glucose homeostasis GO:0042593 24 24 2,000 5,132E-04 0,01630689 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 2,000 5,132E-04 0,0160305 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 5,804E-04 0,01782923 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 5,804E-04 0,01753695 ! heart morphogenesis GO:0003007 25 25 2,000 5,804E-04 0,01725409 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 6,45E-04 0,01886743 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 6,45E-04 0,01857263 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 6,45E-04 0,0182869 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 1,000 6,45E-04 0,01800982 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 6,45E-04 0,01774102 ! pathogenesis GO:0009405 6 6 1,000 6,45E-04 0,01748012 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 1,000 6,45E-04 0,01722679 ! L-phenylalanine metabolic process GO:0006558 6 6 1,000 6,45E-04 0,01698069 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 6 6 1,000 6,45E-04 0,01674153 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 6,45E-04 0,016509 GO:0070667|negative regulation of mast cell proliferation, ! purine base biosynthetic process GO:0009113 6 6 1,000 6,45E-04 0,01628285 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 6,45E-04 0,01606282 ! negative regulation of axonogenesis GO:0050771 7 6 1,000 6,45E-04 0,01584864 ! DNA unwinding during replication GO:0006268 6 6 1,000 6,45E-04 0,01564011 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 6,45E-04 0,01543699 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 6,45E-04 0,01523908 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 6,45E-04 0,01504618 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! maternal placenta development GO:0001893 6 6 1,000 6,45E-04 0,0148581 ! regulation of embryonic development GO:0045995 6 6 1,000 6,45E-04 0,01467467 ! localization within membrane GO:0051668 6 6 1,000 6,45E-04 0,01449571 ! double-strand break repair GO:0006302 27 26 2,000 6,531E-04 0,0145017 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 7,313E-04 0,01604495 ! negative regulation of cell projection organization GO:0031345 8 7 1,000 8,991E-04 0,01949438 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 8,991E-04 0,01926771 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 8,991E-04 0,01904624 GO:0000725|recombinational repair, ! endothelial cell differentiation GO:0045446 7 7 1,000 8,991E-04 0,0188298 ! regulation of mRNA processing GO:0050684 7 7 1,000 8,991E-04 0,01861823 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 8,991E-04 0,01841136 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 8,991E-04 0,01820904 ! regulation of intracellular pH GO:0051453 7 7 1,000 8,991E-04 0,01801112 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 8,991E-04 0,01781745 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of muscle contraction GO:0045932 7 7 1,000 8,991E-04 0,0176279 ! response to gamma radiation GO:0010332 8 7 1,000 8,991E-04 0,01744234 ! negative regulation of T cell activation GO:0050868 7 7 1,000 8,991E-04 0,01726065 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 9,051E-04 0,01719595 ! response to UV GO:0009411 29 29 2,000 9,051E-04 0,01702048 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 9,314E-04 0,0173395 ! striated muscle tissue development GO:0014706 69 67 3,000 9,857E-04 0,01816732 ! negative regulation of cell differentiation GO:0045596 68 67 3,000 9,857E-04 0,01798745 ! response to radiation GO:0009314 70 68 3,000 1,042E-03 0,01883236 ! skeletal muscle fiber development GO:0048741 31 31 2,000 1,103E-03 0,01973609 ! regulation of DNA replication GO:0006275 32 31 2,000 1,103E-03 0,01954632 ! regulation of intracellular transport GO:0032386 31 31 2,000 1,103E-03 0,01936016 ! muscle tissue development GO:0060537 72 70 3,000 1,162E-03 0,02020505 ! 'de novo' protein folding GO:0006458 8 8 1,000 1,194E-03 0,02056039 ! organelle fusion GO:0048284 8 8 1,000 1,194E-03 0,02037001 ! DNA duplex unwinding GO:0032508 8 8 1,000 1,194E-03 0,02018313 GO:0032392|DNA geometric change, ! Golgi organization GO:0007030 8 8 1,000 1,194E-03 0,01999965 ! sex determination GO:0007530 8 8 1,000 1,194E-03 0,01981947 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,194E-03 0,01964251 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,194E-03 0,01946868 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,194E-03 0,01929791 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 1,194E-03 0,0191301 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,194E-03 0,01896518 ! muscle fiber development GO:0048747 32 32 2,000 1,211E-03 0,01908248 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 1,211E-03 0,01892076 ! regulation of cell migration GO:0030334 71 71 3,000 1,225E-03 0,01897965 ! regulation of angiogenesis GO:0045765 35 34 2,000 1,448E-03 0,02223777 ! regulation of protein catabolic process GO:0042176 35 34 2,000 1,448E-03 0,02205398 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,528E-03 0,02308598 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,528E-03 0,02289829 ! glutamine metabolic process GO:0006541 9 9 1,000 1,528E-03 0,02271363 ! nucleobase biosynthetic process GO:0046112 9 9 1,000 1,528E-03 0,02253192 ! regulation of dephosphorylation GO:0035303 9 9 1,000 1,528E-03 0,02235309 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 1,000 1,528E-03 0,02217708 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,528E-03 0,02200382 ! regulation of cellular pH GO:0030641 9 9 1,000 1,528E-03 0,02183325 ! histone acetylation GO:0016573 9 9 1,000 1,528E-03 0,0216653 ! aromatic amino acid family catabolic process GO:0009074 9 9 1,000 1,528E-03 0,02149992 ! purine base metabolic process GO:0006144 9 9 1,000 1,528E-03 0,02133704 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,576E-03 0,0218429 ! positive regulation of cell migration GO:0030335 36 36 2,000 1,712E-03 0,02354062 ! regulation of lipase activity GO:0060191 36 36 2,000 1,712E-03 0,02336624 ! regulation of locomotion GO:0040012 79 79 3,000 1,823E-03 0,02470032 ! regulation of cell motion GO:0051270 79 79 3,000 1,823E-03 0,02452003 ! regulation of transcription factor activity GO:0051090 38 37 2,000 1,854E-03 0,02475932 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 2,000 1,854E-03 0,0245812 GO:0051327|M phase of meiotic cell cycle, ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 1,902E-03 0,0250403 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,902E-03 0,02486271 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 1,902E-03 0,02468762 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,902E-03 0,02451498 ! phototransduction GO:0007602 11 10 1,000 1,902E-03 0,02434474 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,902E-03 0,02417684 ! auditory receptor cell differentiation GO:0042491 10 10 1,000 1,902E-03 0,02401125 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,902E-03 0,02384791 ! fat cell differentiation GO:0045444 10 10 1,000 1,902E-03 0,02368677 ! myoblast differentiation GO:0045445 10 10 1,000 1,902E-03 0,0235278 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 1,902E-03 0,02337095 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! neuromuscular junction development GO:0007528 10 10 1,000 1,902E-03 0,02321617 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 1,902E-03 0,02306344 ! negative regulation of coagulation GO:0050819 11 10 1,000 1,902E-03 0,02291269 ! protein stabilization GO:0050821 10 10 1,000 1,902E-03 0,02276391 ! lymphocyte activation GO:0046649 82 81 3,000 1,999E-03 0,02376602 ! chromosome segregation GO:0007059 38 38 2,000 2,003E-03 0,0236691 ! meiotic cell cycle GO:0051321 38 38 2,000 2,003E-03 0,02351834 ! lymphocyte differentiation GO:0030098 39 39 2,000 2,16E-03 0,02519908 ! positive regulation of cell motion GO:0051272 39 39 2,000 2,16E-03 0,0250406 ! blood vessel morphogenesis GO:0048514 84 83 3,000 2,186E-03 0,02518346 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 2,315E-03 0,02649977 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 2,315E-03 0,02633619 ! signal complex assembly GO:0007172 11 11 1,000 2,315E-03 0,02617462 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,315E-03 0,02601502 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 2,315E-03 0,02585735 GO:0032388|positive regulation of intracellular transport, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 1,000 2,315E-03 0,02570159 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 2,315E-03 0,02554768 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 2,315E-03 0,02539561 ! G1/S transition checkpoint GO:0031575 12 11 1,000 2,315E-03 0,02524535 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 1,000 2,315E-03 0,02509684 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 1,000 2,315E-03 0,02495008 ! regulation of ARF GTPase activity GO:0032312 11 11 1,000 2,315E-03 0,02480502 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,315E-03 0,02466164 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,315E-03 0,0245199 GO:0006109|regulation of carbohydrate metabolic process, ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 2,315E-03 0,02437979 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 2,315E-03 0,02424127 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 2,49E-03 0,02592608 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 2,49E-03 0,02578043 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,766E-03 0,02848048 ! cell fate determination GO:0001709 12 12 1,000 2,766E-03 0,02832225 ! somitogenesis GO:0001756 13 12 1,000 2,766E-03 0,02816578 ! detection of light stimulus GO:0009583 13 12 1,000 2,766E-03 0,02801102 ! aromatic compound catabolic process GO:0019439 13 12 1,000 2,766E-03 0,02785795 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 2,766E-03 0,02770655 ! protein import into nucleus GO:0006606 44 44 2,000 3,059E-03 0,0304694 ! positive regulation of DNA replication GO:0045740 14 13 1,000 3,255E-03 0,03225447 ! negative regulation of protein modification process GO:0031400 13 13 1,000 3,255E-03 0,03208198 ! vasculogenesis GO:0001570 13 13 1,000 3,255E-03 0,03191134 ! mitochondrial membrane organization GO:0007006 13 13 1,000 3,255E-03 0,03174249 ! negative regulation of DNA replication GO:0008156 13 13 1,000 3,255E-03 0,03157543 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 3,255E-03 0,03141011 GO:0051384|response to glucocorticoid stimulus, ! receptor metabolic process GO:0043112 14 13 1,000 3,255E-03 0,03124652 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 3,255E-03 0,03108462 ! cell aging GO:0007569 13 13 1,000 3,255E-03 0,03092439 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 3,255E-03 0,0307658 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,255E-03 0,03060883 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 3,255E-03 0,03045346 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 3,255E-03 0,03029965 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleobase metabolic process GO:0009112 13 13 1,000 3,255E-03 0,03014739 ! regulation of axonogenesis GO:0050770 14 13 1,000 3,255E-03 0,02999666 ! negative regulation of phosphorylation GO:0042326 13 13 1,000 3,255E-03 0,02984742 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,255E-03 0,02969966 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 3,255E-03 0,02955335 ! blastocyst development GO:0001824 13 13 1,000 3,255E-03 0,02940849 ! tissue homeostasis GO:0001894 13 13 1,000 3,255E-03 0,02926503 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 1,000 3,255E-03 0,02912297 ! regulation of DNA binding GO:0051101 47 45 2,000 3,262E-03 0,02904052 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 3,262E-03 0,02890091 ! nuclear import GO:0051170 45 45 2,000 3,262E-03 0,02876262 ! blood vessel development GO:0001568 95 94 3,000 3,439E-03 0,03018414 ! vasculature development GO:0001944 97 96 3,000 3,71E-03 0,0324089 ! protein amino acid acylation GO:0043543 14 14 1,000 3,782E-03 0,03287505 ! regulation of neuron projection development GO:0010975 15 14 1,000 3,782E-03 0,03272071 ! mechanoreceptor differentiation GO:0042490 14 14 1,000 3,782E-03 0,03256781 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 3,782E-03 0,03241633 GO:0045936|negative regulation of phosphate metabolic process, ! base-excision repair GO:0006284 14 14 1,000 3,782E-03 0,03226625 ! response to organic cyclic substance GO:0014070 15 14 1,000 3,782E-03 0,03211756 ! regulation of blood coagulation GO:0030193 15 14 1,000 3,782E-03 0,03197023 ! protein localization in nucleus GO:0034504 48 48 2,000 3,921E-03 0,03299321 ! glycoprotein metabolic process GO:0009100 99 98 3,000 3,996E-03 0,03347304 ! cell cycle arrest GO:0007050 49 49 2,000 4,157E-03 0,0346651 ! muscle organ development GO:0007517 102 100 3,000 4,296E-03 0,03566072 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 4,345E-03 0,03590863 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 4,345E-03 0,03574832 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 4,345E-03 0,03558944 ! detection of stimulus involved in sensory perception GO:0050906 16 15 1,000 4,345E-03 0,03543196 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 4,345E-03 0,03527587 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 4,345E-03 0,03512116 ! response to ionizing radiation GO:0010212 16 15 1,000 4,345E-03 0,03496779 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 4,345E-03 0,03481575 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 4,345E-03 0,03466504 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 4,345E-03 0,03451562 ! protein homooligomerization GO:0051260 15 15 1,000 4,345E-03 0,03436748 ! negative regulation of transport GO:0051051 51 50 2,000 4,402E-03 0,03466724 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 4,402E-03 0,03451972 ! regulation of neurogenesis GO:0050767 51 50 2,000 4,402E-03 0,03437345 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 4,917E-03 0,03823674 ! cell fate commitment GO:0045165 52 52 2,000 4,917E-03 0,03807608 ! segmentation GO:0035282 17 16 1,000 4,945E-03 0,0381287 ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 1,000 4,945E-03 0,03796983 ! regulation of coagulation GO:0050818 17 16 1,000 4,945E-03 0,03781228 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 4,945E-03 0,03765603 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 4,945E-03 0,03750106 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 4,945E-03 0,03734737 ! regulation of protein transport GO:0051223 53 53 2,000 5,188E-03 0,03902551 GO:0070201|regulation of establishment of protein localization, ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 5,468E-03 0,04096219 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 5,58E-03 0,04163568 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 5,58E-03 0,04146779 ! myelination GO:0042552 17 17 1,000 5,58E-03 0,04130126 ! regulation of transmembrane transport GO:0034762 17 17 1,000 5,58E-03 0,04113605 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 5,58E-03 0,04097216 ! in utero embryonic development GO:0001701 55 55 2,000 5,756E-03 0,04209762 ! regulation of nervous system development GO:0051960 57 56 2,000 6,054E-03 0,0440992 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 6,251E-03 0,04535627 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 6,251E-03 0,0451784 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 6,251E-03 0,04500192 ! striated muscle contraction GO:0006941 18 18 1,000 6,251E-03 0,04482682 ! negative regulation of DNA binding GO:0043392 19 18 1,000 6,251E-03 0,04465307 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 6,251E-03 0,04448067 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! B cell differentiation GO:0030183 18 18 1,000 6,251E-03 0,04430959 ! ensheathment of neurons GO:0007272 18 18 1,000 6,251E-03 0,04413982 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 6,251E-03 0,04397134 ! regulation of binding GO:0051098 60 57 2,000 6,36E-03 0,04457157 ! regulation of protein localization GO:0032880 58 57 2,000 6,36E-03 0,04440274 ! DNA damage checkpoint GO:0000077 19 19 1,000 6,957E-03 0,0483823 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 6,957E-03 0,04820042 ! regulation of pH GO:0006885 19 19 1,000 6,957E-03 0,04801989 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 6,957E-03 0,04784071 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 6,957E-03 0,04766287 ! peripheral nervous system development GO:0007422 19 19 1,000 6,957E-03 0,04748634 ! regulation of protein stability GO:0031647 19 19 1,000 6,957E-03 0,04731111 ! placenta development GO:0001890 19 19 1,000 6,957E-03 0,04713717 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 7,001E-03 0,04726553 ! regulation of cell development GO:0060284 60 59 2,000 7,001E-03 0,04709303 ! cellular aromatic compound metabolic process GO:0006725 60 59 2,000 7,001E-03 0,04692179 ! protein localization in organelle GO:0033365 59 59 2,000 7,001E-03 0,04675178 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 7,679E-03 0,05109422 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 7,697E-03 0,05102731 ! negative regulation of binding GO:0051100 21 20 1,000 7,697E-03 0,05084441 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 7,697E-03 0,05066283 ! detection of abiotic stimulus GO:0009582 21 20 1,000 7,697E-03 0,05048253 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 7,697E-03 0,05030352 ! protein import GO:0017038 62 62 2,000 8,032E-03 0,05231045 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 8,395E-03 0,05447911 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 8,471E-03 0,05478058 ! mammary gland development GO:0030879 23 21 1,000 8,471E-03 0,05458904 ! DNA integrity checkpoint GO:0031570 21 21 1,000 8,471E-03 0,05439883 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 8,471E-03 0,05420995 ! regulation of action potential in neuron GO:0019228 21 21 1,000 8,471E-03 0,05402237 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 8,471E-03 0,05383609 ! angiogenesis GO:0001525 65 64 2,000 8,767E-03 0,05552521 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 9,279E-03 0,05856531 GO:0090047|positive regulation of transcription regulator activity, ! maintenance of protein location in cell GO:0032507 23 22 1,000 9,279E-03 0,05836543 ! spindle organization GO:0007051 22 22 1,000 9,279E-03 0,05816691 ! pigment biosynthetic process GO:0046148 22 22 1,000 9,279E-03 0,05796973 ! detection of external stimulus GO:0009581 23 22 1,000 9,279E-03 0,05777389 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 9,54E-03 0,0592001 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01011967 0,06258577 ! regulation of ARF protein signal transduction GO:0032012 23 23 1,000 0,01011967 0,06237645 ! positive regulation of growth GO:0045927 23 23 1,000 0,01011967 0,06216853 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,01011967 0,06196199 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01011967 0,06175682 ! response to nutrient levels GO:0031667 69 69 2,000 0,01077231 0,06552264 ! mitochondrial transport GO:0006839 24 24 1,000 0,01099299 0,06664501 ! regulation of action potential GO:0001508 24 24 1,000 0,01099299 0,0664265 ! maintenance of protein location GO:0045185 25 24 1,000 0,01099299 0,06620942 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01099299 0,06599375 ! wound healing GO:0042060 74 70 2,000 0,01120261 0,06703382 ! endosome transport GO:0016197 25 25 1,000 0,01189843 0,07096701 ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01189843 0,07073808 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01189843 0,07051063 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01189843 0,07028464 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,01209285 0,07120484 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,01209285 0,07097808 ! positive regulation of binding GO:0051099 27 26 1,000 0,01283554 0,07509811 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01283554 0,07486045 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01283554 0,0746243 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01283554 0,07438963 ! pigment metabolic process GO:0042440 26 26 1,000 0,01283554 0,07415644 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01283554 0,0739247 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01283554 0,0736944 ! synapse organization GO:0050808 26 26 1,000 0,01283554 0,07346554 ! learning or memory GO:0007611 28 27 1,000 0,01380388 0,07876332 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01380388 0,07852023 ! activation of caspase activity GO:0006919 27 27 1,000 0,01380388 0,07827863 ! inner ear development GO:0048839 27 27 1,000 0,01380388 0,07803851 ! glutamine family amino acid metabolic process GO:0009064 28 27 1,000 0,01380388 0,07779986 ! regulation of muscle contraction GO:0006937 28 28 1,000 0,01480301 0,08317666 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01480301 0,08292384 ! histone modification GO:0016570 28 28 1,000 0,01480301 0,08267256 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01480301 0,08242279 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01500303 0,08328489 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,01500303 0,08303479 ! nuclear transport GO:0051169 79 79 2,000 0,01552331 0,08565704 GO:0006913|nucleocytoplasmic transport, ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01583249 0,08710231 ! viral reproductive process GO:0022415 29 29 1,000 0,01583249 0,08684308 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01583249 0,08658538 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,01583249 0,08632921 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01583249 0,08607455 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01583249 0,08582139 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,01689188 0,09129544 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01689188 0,09102849 GO:0010863|positive regulation of phospholipase C activity, ! vesicle organization GO:0016050 30 30 1,000 0,01689188 0,0907631 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01689188 0,09049925 ! membrane fusion GO:0006944 31 31 1,000 0,01798077 0,09605381 ! B cell activation GO:0042113 31 31 1,000 0,01798077 0,0957762 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01798077 0,09550019 ! aging GO:0007568 32 31 1,000 0,01798077 0,09522576 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,01798077 0,09495291 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,01798077 0,09468162 ! regulation of cellular localization GO:0060341 86 85 2,000 0,01885857 0,09902091 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,01885857 0,0987396 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,01909873 0,09971377 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01909873 0,09943209 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01909873 0,099152 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01909873 0,09887348 ! maintenance of location GO:0051235 33 32 1,000 0,01909873 0,09859653 ! negative regulation of cell size GO:0045792 33 33 1,000 0,02024534 0,10422389 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,02024534 0,10393358 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02024534 0,10364487 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 0,02024534 0,10335777 ! response to metal ion GO:0010038 34 34 1,000 0,02142017 0,10905354 ! ear development GO:0043583 34 34 1,000 0,02142017 0,10875311 ! muscle cell differentiation GO:0042692 35 34 1,000 0,02142017 0,10845434 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,02142017 0,10815721 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02142017 0,10786169 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02142017 0,10756779 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 0,02142017 0,10727549 ! viral reproduction GO:0016032 34 34 1,000 0,02142017 0,10698477 ! detection of stimulus GO:0051606 36 34 1,000 0,02142017 0,10669562 ! regulation of Ras protein signal transduction GO:0046578 90 90 2,000 0,02191937 0,10888789 ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,02256236 0,11178071 ! mesoderm development GO:0007498 35 35 1,000 0,02262283 0,11177984 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,02262283 0,11148097 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02262283 0,11118368 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,02262283 0,11088798 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02262283 0,11059385 ! visual perception GO:0007601 93 92 2,000 0,02321562 0,11319152 GO:0050953|sensory perception of light stimulus, ! response to inorganic substance GO:0010035 36 36 1,000 0,02385291 0,11599184 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02385291 0,1156866 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,02385291 0,11538296 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02385291 0,11508091 ! coagulation GO:0050817 39 36 1,000 0,02385291 0,11478044 GO:0007596|blood coagulation, ! tissue morphogenesis GO:0048729 94 93 2,000 0,02387918 0,11460762 ! epidermis development GO:0008544 94 94 2,000 0,02455302 0,11753562 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02510999 0,11989045 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! response to drug GO:0042493 37 37 1,000 0,02510999 0,11958066 ! lung development GO:0030324 38 37 1,000 0,02510999 0,11927246 ! negative regulation of growth GO:0045926 37 37 1,000 0,02510999 0,11896585 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,02510999 0,11866081 ! cellular amino acid catabolic process GO:0009063 38 37 1,000 0,02510999 0,11835733 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,02510999 0,11805539 ! regulation of cell growth GO:0001558 97 96 2,000 0,02593156 0,12160779 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,02639369 0,12346083 ! axon guidance GO:0007411 39 38 1,000 0,02639369 0,12314827 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,02639369 0,12283729 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,0277036 0,1286089 ! hemostasis GO:0007599 42 39 1,000 0,0277036 0,12828576 ! activation of MAPK activity GO:0000187 39 39 1,000 0,0277036 0,12796425 ! respiratory tube development GO:0030323 40 39 1,000 0,0277036 0,12764434 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,0277036 0,12732602 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,0277036 0,12700929 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,0277036 0,12669413 ! respiratory system development GO:0060541 40 39 1,000 0,0277036 0,12638053 ! response to hormone stimulus GO:0009725 102 100 2,000 0,02881194 0,1311121 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,02881194 0,13078917 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02903934 0,13149754 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,02903934 0,13117524 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02903934 0,13085452 ! organelle localization GO:0051640 41 40 1,000 0,02903934 0,13053536 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03040051 0,13632151 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 0,03040051 0,13599063 ! amine catabolic process GO:0009310 42 41 1,000 0,03040051 0,13566136 ! regulation of caspase activity GO:0043281 41 41 1,000 0,03040051 0,13533367 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 0,03040051 0,13500757 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,03178674 0,14082441 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03178674 0,1404867 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,03178674 0,14015061 ! protein ubiquitination GO:0016567 43 42 1,000 0,03178674 0,13981612 ! rRNA transcription GO:0009303 5 5 0,000 0,03299564 0,14478803 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03299564 0,14444411 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03299564 0,14410183 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03299564 0,14376116 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03299564 0,1434221 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03299564 0,14308464 ! reproductive cellular process GO:0048610 5 5 0,000 0,03299564 0,14274876 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03299564 0,14241445 ! prostate gland development GO:0030850 5 5 0,000 0,03299564 0,14208171 ! metencephalon development GO:0022037 5 5 0,000 0,03299564 0,14175052 ! water transport GO:0006833 5 5 0,000 0,03299564 0,14142087 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03299564 0,14109274 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03299564 0,14076614 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03299564 0,14044104 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03299564 0,14011745 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03299564 0,13979534 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03299564 0,13947471 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03299564 0,13915554 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03299564 0,13883784 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03299564 0,13852158 ! CTP metabolic process GO:0046036 5 5 0,000 0,03299564 0,13820675 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03299564 0,13789336 ! GTP metabolic process GO:0046039 5 5 0,000 0,03299564 0,13758139 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03299564 0,13727082 ! mRNA stabilization GO:0048255 5 5 0,000 0,03299564 0,13696165 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03299564 0,13665387 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03299564 0,13634747 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03299564 0,13604244 ! social behavior GO:0035176 5 5 0,000 0,03299564 0,13573878 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03299564 0,13543646 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03299564 0,13513549 ! memory GO:0007613 5 5 0,000 0,03299564 0,13483586 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03299564 0,13453755 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03299564 0,13424056 ! response to lipid GO:0033993 5 5 0,000 0,03299564 0,13394487 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03299564 0,13365049 ! hippocampus development GO:0021766 6 5 0,000 0,03299564 0,1333574 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03299564 0,13306558 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03299564 0,13277505 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03299564 0,13248578 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03299564 0,13219777 ! heart looping GO:0001947 5 5 0,000 0,03299564 0,131911 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03299564 0,13162548 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03299564 0,13134119 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03299564 0,13105813 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03299564 0,13077628 ! pH reduction GO:0045851 5 5 0,000 0,03299564 0,13049565 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03299564 0,13021621 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03299564 0,12993797 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03299564 0,12966092 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03299564 0,12938505 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03299564 0,12911034 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03299564 0,12883681 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03299564 0,12856442 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03299564 0,12829319 ! adrenal gland development GO:0030325 5 5 0,000 0,03299564 0,1280231 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03299564 0,12775414 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03299564 0,12748631 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03299564 0,12721961 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03299564 0,12695401 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03299564 0,12668953 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03299564 0,12642614 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03299564 0,12616384 GO:0033135|regulation of peptidyl-serine phosphorylation, ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03299564 0,12590263 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03299564 0,1256425 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03299564 0,12538345 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03299564 0,12512546 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03299564 0,12486853 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03299564 0,12461265 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03299564 0,12435782 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03299564 0,12410402 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03299564 0,12385127 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03299564 0,12359954 ! response to ATP GO:0033198 5 5 0,000 0,03299564 0,12334883 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03299564 0,12309913 ! regulation of appetite GO:0032098 5 5 0,000 0,03299564 0,12285045 GO:0032095|regulation of response to food, ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03299564 0,12260277 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03299564 0,12235608 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03299564 0,12211039 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03299564 0,12186568 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03299564 0,12162194 ! fear response GO:0042596 5 5 0,000 0,03299564 0,12137919 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03299564 0,12113739 ! retinol metabolic process GO:0042572 5 5 0,000 0,03299564 0,12089656 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03299564 0,12065669 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03299564 0,12041777 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03299564 0,12017979 ! parturition GO:0007567 5 5 0,000 0,03299564 0,11994275 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03299564 0,11970664 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03299564 0,11947146 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03299564 0,1192372 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03299564 0,11900386 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03299564 0,11877143 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03299564 0,11853991 ! response to UV-B GO:0010224 5 5 0,000 0,03299564 0,11830928 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03299564 0,11807956 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03299564 0,11785072 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03299564 0,11762277 ! interaction with symbiont GO:0051702 5 5 0,000 0,03299564 0,1173957 ! cellular extravasation GO:0045123 5 5 0,000 0,03299564 0,1171695 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03299564 0,11694418 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03299564 0,11671972 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03299564 0,11649612 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03299564 0,11627337 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03299564 0,11605147 ! response to amine stimulus GO:0014075 5 5 0,000 0,03299564 0,11583042 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03299564 0,11561021 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03299564 0,11539084 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03299564 0,1151723 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03299564 0,11495458 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03299564 0,11473768 ! neuron recognition GO:0008038 5 5 0,000 0,03299564 0,1145216 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03299564 0,11430634 ! hair follicle maturation GO:0048820 5 5 0,000 0,03299564 0,11409188 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03299564 0,11387823 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03299564 0,11366537 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03299564 0,11345331 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03299564 0,11324203 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03299564 0,11303155 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03299564 0,11282184 ! postreplication repair GO:0006301 5 5 0,000 0,03299564 0,11261291 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03299564 0,11240475 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,03299564 0,11219737 ! histone methylation GO:0016571 5 5 0,000 0,03299564 0,11199074 ! DNA methylation GO:0006306 5 5 0,000 0,03299564 0,11178488 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03299564 0,11157977 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03299564 0,11137541 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03299564 0,1111718 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03299564 0,11096893 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03299564 0,1107668 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03299564 0,1105654 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03299564 0,11036474 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03299564 0,1101648 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03299564 0,10996559 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03299564 0,1097671 ! sterol catabolic process GO:0016127 5 5 0,000 0,03299564 0,10956932 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03299564 0,10937225 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03299564 0,10917589 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03299564 0,10898024 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03299564 0,10878528 ! zymogen activation GO:0031638 5 5 0,000 0,03299564 0,10859102 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03299564 0,10839745 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03299564 0,10820458 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03299564 0,10801238 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03299564 0,10782087 ! nucleosome positioning GO:0016584 5 5 0,000 0,03299564 0,10763004 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03299564 0,10743988 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03299564 0,10725039 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03299564 0,10706157 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03299564 0,10687341 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03299564 0,10668592 ! NADPH regeneration GO:0006740 5 5 0,000 0,03299564 0,10649908 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03299564 0,10631289 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03299564 0,10612735 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03299564 0,10594246 GO:0002688|regulation of leukocyte chemotaxis, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03299564 0,10575821 ! sarcomere organization GO:0045214 5 5 0,000 0,03299564 0,1055746 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03299564 0,10539163 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03299564 0,10520929 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03299564 0,10502759 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03299564 0,1048465 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03299564 0,10466605 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03299564 0,10448621 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03299564 0,10430698 ! spleen development GO:0048536 5 5 0,000 0,03299564 0,10412838 ! male genitalia development GO:0030539 5 5 0,000 0,03299564 0,10395038 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03299564 0,10377299 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03299564 0,1035962 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03299564 0,10342002 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03299564 0,10324443 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03299564 0,10306944 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03299564 0,10289505 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03299564 0,10272124 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03299564 0,10254801 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03299564 0,10237537 ! ATP catabolic process GO:0006200 5 5 0,000 0,03299564 0,10220331 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03299564 0,10203183 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03299564 0,10186092 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03299564 0,10169059 ! embryonic gut development GO:0048566 5 5 0,000 0,03299564 0,10152082 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03299564 0,10135162 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03299564 0,10118298 ! activation of innate immune response GO:0002218 5 5 0,000 0,03299564 0,1010149 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03299564 0,10084738 ! catecholamine transport GO:0051937 5 5 0,000 0,03299564 0,10068042 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03299564 0,100514 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03299564 0,10034814 ! muscle adaptation GO:0043500 5 5 0,000 0,03299564 0,10018282 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03299564 0,10001805 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03299564 0,09985381 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03299564 0,09969012 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03299564 0,09952696 ! defense response to fungus GO:0050832 5 5 0,000 0,03299564 0,09936433 ! lysogeny GO:0030069 5 5 0,000 0,03299564 0,09920224 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03299564 0,09904067 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03299564 0,09887963 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03299564 0,09871911 ! response to nicotine GO:0035094 5 5 0,000 0,03299564 0,09855911 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03299564 0,09839963 ! mitochondrion localization GO:0051646 5 5 0,000 0,03299564 0,09824067 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03299564 0,09808221 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,03319764 0,09852374 ! mitochondrion organization GO:0007005 44 43 1,000 0,03319764 0,09836534 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03319764 0,09820745 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,03609195 0,10659851 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,03757463 0,11080007 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,03757463 0,11062307 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,03757463 0,11044664 ! regulation of membrane potential GO:0042391 46 46 1,000 0,03757463 0,11027077 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03946578 0,11563662 ! axon extension GO:0048675 7 6 0,000 0,03946578 0,11545307 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03946578 0,11527011 ! tRNA modification GO:0006400 6 6 0,000 0,03946578 0,11508772 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03946578 0,1149059 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03946578 0,11472466 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03946578 0,114544 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03946578 0,11436389 ! regulation of S phase GO:0033261 6 6 0,000 0,03946578 0,11418436 ! myotube differentiation GO:0014902 6 6 0,000 0,03946578 0,11400539 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03946578 0,11382697 ! bone remodeling GO:0046849 6 6 0,000 0,03946578 0,11364912 ! N-glycan processing GO:0006491 6 6 0,000 0,03946578 0,11347182 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03946578 0,11329507 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03946578 0,11311888 ! RNA methylation GO:0001510 6 6 0,000 0,03946578 0,11294323 ! cartilage condensation GO:0001502 7 6 0,000 0,03946578 0,11276812 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03946578 0,11259356 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03946578 0,11241953 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,03946578 0,11224604 ! artery development GO:0060840 6 6 0,000 0,03946578 0,11207309 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03946578 0,11190067 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03946578 0,11172878 ! androgen metabolic process GO:0008209 6 6 0,000 0,03946578 0,11155742 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03946578 0,11138658 ! limbic system development GO:0021761 7 6 0,000 0,03946578 0,11121626 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03946578 0,11104647 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03946578 0,11087719 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03946578 0,11070843 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03946578 0,11054018 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03946578 0,11037244 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03946578 0,11020521 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03946578 0,11003848 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03946578 0,10987226 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03946578 0,10970654 ! arginine metabolic process GO:0006525 6 6 0,000 0,03946578 0,10954132 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03946578 0,1093766 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03946578 0,10921237 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03946578 0,10904863 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03946578 0,10888538 GO:0010833|telomere maintenance via telomere lengthening, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03946578 0,10872263 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03946578 0,10856035 ! V(D)J recombination GO:0033151 6 6 0,000 0,03946578 0,10839856 ! focal adhesion formation GO:0048041 7 6 0,000 0,03946578 0,10823726 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03946578 0,10807643 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03946578 0,10791608 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03946578 0,1077562 ! regulation of heart rate GO:0002027 6 6 0,000 0,03946578 0,1075968 ! lipid digestion GO:0044241 6 6 0,000 0,03946578 0,10743787 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03946578 0,10727941 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03946578 0,10712141 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03946578 0,10696388 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03946578 0,10680681 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03946578 0,1066502 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03946578 0,10649405 ! ruffle organization GO:0031529 6 6 0,000 0,03946578 0,10633836 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,03946578 0,10618312 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03946578 0,10602833 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03946578 0,105874 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03946578 0,10572011 ! L-amino acid transport GO:0015807 6 6 0,000 0,03946578 0,10556667 ! bone mineralization GO:0030282 6 6 0,000 0,03946578 0,10541368 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03946578 0,10526112 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03946578 0,10510901 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03946578 0,10495734 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,03946578 0,10480611 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03946578 0,1046553 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03946578 0,10450494 ! regulation of organ growth GO:0046620 6 6 0,000 0,03946578 0,104355 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03946578 0,1042055 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03946578 0,10405642 ! response to dsRNA GO:0043331 6 6 0,000 0,03946578 0,10390777 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03946578 0,10375954 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03946578 0,10361173 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03946578 0,10346435 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03946578 0,10331738 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03946578 0,10317083 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03946578 0,1030247 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03946578 0,10287898 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03946578 0,10273367 ! erythrocyte development GO:0048821 6 6 0,000 0,03946578 0,10258877 ! renal water homeostasis GO:0003091 6 6 0,000 0,03946578 0,10244428 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03946578 0,10230019 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03946578 0,10215651 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03946578 0,10201324 ! ribosome assembly GO:0042255 6 6 0,000 0,03946578 0,10187036 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03946578 0,10172788 ! diencephalon development GO:0021536 6 6 0,000 0,03946578 0,10158581 ! fucose catabolic process GO:0019317 6 6 0,000 0,03946578 0,10144412 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03946578 0,10130284 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03946578 0,10116194 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03946578 0,10102144 ! regulation of cell division GO:0051302 6 6 0,000 0,03946578 0,10088133 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03946578 0,1007416 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03946578 0,10060226 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03946578 0,10046331 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03946578 0,10032474 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03946578 0,10018655 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03946578 0,10004874 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03946578 0,09991131 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03946578 0,09977426 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03946578 0,09963758 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03946578 0,09950128 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03946578 0,09936535 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03946578 0,09922979 ! thymus development GO:0048538 6 6 0,000 0,03946578 0,0990946 ! lymph node development GO:0048535 6 6 0,000 0,03946578 0,09895978 ! organic cation transport GO:0015695 6 6 0,000 0,03946578 0,09882532 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03946578 0,09869123 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03946578 0,0985575 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03946578 0,09842414 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03946578 0,09829113 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03946578 0,09815848 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03946578 0,0980262 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03946578 0,09789426 ! alditol metabolic process GO:0019400 6 6 0,000 0,03946578 0,09776268 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03946578 0,09763146 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03946578 0,09750059 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03946578 0,09737006 ! actin filament organization GO:0007015 50 48 1,000 0,04060919 0,10005714 ! DNA recombination GO:0006310 48 48 1,000 0,04060919 0,09992355 ! ossification GO:0001503 50 49 1,000 0,04216036 0,10360205 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,04216036 0,10346409 ! nitrogen compound catabolic process GO:0044270 51 50 1,000 0,04373364 0,1071823 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,04373364 0,10703996 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,04373364 0,106898 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,04532868 0,11065002 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,04532868 0,11050366 GO:0051325|interphase, ! respiratory burst GO:0045730 7 7 0,000 0,04589356 0,11173294 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04589356 0,11158554 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04589356 0,11143852 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04589356 0,11129189 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04589356 0,11114565 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04589356 0,11099979 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04589356 0,11085431 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04589356 0,11070921 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04589356 0,1105645 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04589356 0,11042016 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04589356 0,11027619 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04589356 0,1101326 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04589356 0,10998939 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04589356 0,10984654 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04589356 0,10970407 ! axis specification GO:0009798 7 7 0,000 0,04589356 0,10956197 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04589356 0,10942023 ! visual behavior GO:0007632 7 7 0,000 0,04589356 0,10927886 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04589356 0,10913786 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04589356 0,10899722 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04589356 0,10885694 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04589356 0,10871702 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04589356 0,10857746 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04589356 0,10843826 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04589356 0,10829941 ! digestive system development GO:0055123 7 7 0,000 0,04589356 0,10816092 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04589356 0,10802278 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04589356 0,107885 ! protein targeting to ER GO:0045047 8 7 0,000 0,04589356 0,10774757 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04589356 0,10761048 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04589356 0,10747375 ! endoderm development GO:0007492 7 7 0,000 0,04589356 0,10733736 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04589356 0,10720132 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04589356 0,10706562 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04589356 0,10693026 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04589356 0,10679525 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04589356 0,10666058 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04589356 0,10652625 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04589356 0,10639225 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04589356 0,10625859 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04589356 0,10612527 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04589356 0,10599228 ! UV protection GO:0009650 7 7 0,000 0,04589356 0,10585962 ! DNA integration GO:0015074 7 7 0,000 0,04589356 0,1057273 ! myofibril assembly GO:0030239 7 7 0,000 0,04589356 0,10559531 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04589356 0,10546364 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04589356 0,1053323 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04589356 0,10520129 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04589356 0,10507061 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04589356 0,10494025 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04589356 0,10481021 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04589356 0,10468049 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04589356 0,1045511 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04589356 0,10442202 ! axon cargo transport GO:0008088 7 7 0,000 0,04589356 0,10429327 ! eating behavior GO:0042755 7 7 0,000 0,04589356 0,10416483 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04589356 0,1040367 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04589356 0,10390889 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04589356 0,1037814 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04589356 0,10365421 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04589356 0,10352734 ! cranial nerve development GO:0021545 7 7 0,000 0,04589356 0,10340078 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04589356 0,10327453 ! induction of an organ GO:0001759 7 7 0,000 0,04589356 0,10314858 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04589356 0,10302295 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04589356 0,10289761 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04589356 0,10277259 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04589356 0,10264786 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04589356 0,10252344 ! platelet activation GO:0030168 8 7 0,000 0,04589356 0,10239932 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04589356 0,1022755 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04589356 0,10215198 ! natural killer cell activation GO:0030101 7 7 0,000 0,04589356 0,10202876 ! NADP metabolic process GO:0006739 7 7 0,000 0,04589356 0,10190583 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04589356 0,1017832 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04589356 0,10166086 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04589356 0,10153882 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04589356 0,10141707 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04589356 0,10129562 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04589356 0,10117445 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04589356 0,10105357 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04589356 0,10093298 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04589356 0,10081268 ! cell-cell recognition GO:0009988 8 7 0,000 0,04589356 0,10069267 ! hormone catabolic process GO:0042447 7 7 0,000 0,04589356 0,10057294 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04589356 0,10045349 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04589356 0,10033433 ! oxygen transport GO:0015671 7 7 0,000 0,04589356 0,10021545 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04589356 0,10009685 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,04589356 0,09997853 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04589356 0,0998605 ! regulation of axon extension GO:0030516 7 7 0,000 0,04589356 0,09974274 ! cell killing GO:0001906 7 7 0,000 0,04589356 0,09962525 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04589356 0,09950805 ! adult feeding behavior GO:0008343 7 7 0,000 0,04589356 0,09939112 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04589356 0,09927446 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04589356 0,09915808 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04589356 0,09904197 ! response to cold GO:0009409 7 7 0,000 0,04589356 0,09892613 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,04694515 0,10107466 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,04694515 0,10095672 ! response to hypoxia GO:0001666 53 53 1,000 0,04858269 0,10435653 ! regulation of T cell activation GO:0050863 53 53 1,000 0,04858269 0,10423504 ! response to oxygen levels GO:0070482 55 54 1,000 0,05024097 0,10766756 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05191964 0,11113576 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,05191964 0,11100683 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,05191964 0,11087821 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,05227926 0,11151699 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05227926 0,11138807 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05227926 0,11125944 ! positive regulation of translation GO:0045727 8 8 0,000 0,05227926 0,11113112 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05227926 0,11100309 ! superoxide anion generation GO:0042554 8 8 0,000 0,05227926 0,11087535 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05227926 0,11074791 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05227926 0,11062076 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05227926 0,1104939 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05227926 0,11036733 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05227926 0,11024105 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,05227926 0,11011506 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05227926 0,10998936 ! zinc ion transport GO:0006829 8 8 0,000 0,05227926 0,10986394 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05227926 0,10973881 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05227926 0,10961397 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,05227926 0,10948941 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05227926 0,10936513 ! lipid localization GO:0010876 8 8 0,000 0,05227926 0,10924113 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,05227926 0,10911742 ! response to cAMP GO:0051591 8 8 0,000 0,05227926 0,10899398 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05227926 0,10887082 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05227926 0,10874794 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,05227926 0,10862534 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05227926 0,10850302 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05227926 0,10838097 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05227926 0,10825919 ! sensory perception of taste GO:0050909 8 8 0,000 0,05227926 0,10813769 ! pancreas development GO:0031016 8 8 0,000 0,05227926 0,10801646 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05227926 0,1078955 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,05227926 0,10777481 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05227926 0,10765439 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05227926 0,10753424 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05227926 0,10741436 ! sperm motility GO:0030317 8 8 0,000 0,05227926 0,10729474 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05227926 0,10717539 ! glycine metabolic process GO:0006544 8 8 0,000 0,05227926 0,10705631 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05227926 0,10693749 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05227926 0,10681893 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,05227926 0,10670064 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05227926 0,10658261 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05227926 0,10646484 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05227926 0,10634733 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,05227926 0,10623008 ! fructose metabolic process GO:0006000 8 8 0,000 0,05227926 0,10611308 ! mannose metabolic process GO:0006013 9 8 0,000 0,05227926 0,10599635 ! NAD metabolic process GO:0019674 8 8 0,000 0,05227926 0,10587987 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,05227926 0,10576364 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05227926 0,10564767 ! response to fungus GO:0009620 8 8 0,000 0,05227926 0,10553196 ! stem cell differentiation GO:0048863 8 8 0,000 0,05227926 0,1054165 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,05227926 0,10530129 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05227926 0,10518633 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05227926 0,10507162 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05227926 0,10495717 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05227926 0,10484296 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05227926 0,104729 ! vasoconstriction GO:0042310 8 8 0,000 0,05227926 0,10461529 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05227926 0,10450182 ! muscle cell development GO:0055001 8 8 0,000 0,05227926 0,1043886 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05227926 0,10427563 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05227926 0,1041629 ! sensory perception of pain GO:0019233 8 8 0,000 0,05227926 0,10405041 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05227926 0,10393817 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05227926 0,10382616 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05227926 0,1037144 ! chromatin silencing GO:0006342 8 8 0,000 0,05227926 0,10360288 ! tissue regeneration GO:0042246 8 8 0,000 0,05227926 0,1034916 ! salivary gland development GO:0007431 8 8 0,000 0,05227926 0,10338056 ! T cell homeostasis GO:0043029 8 8 0,000 0,05227926 0,10326975 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05227926 0,10315919 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,05227926 0,10304885 ! water homeostasis GO:0030104 8 8 0,000 0,05227926 0,10293876 ! cofactor transport GO:0051181 8 8 0,000 0,05227926 0,1028289 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05227926 0,10271927 ! acid secretion GO:0046717 8 8 0,000 0,05227926 0,10260988 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,05227926 0,10250072 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05227926 0,10239179 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05227926 0,1022831 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05227926 0,10217463 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,05227926 0,1020664 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05227926 0,10195839 ! regulation of RNA stability GO:0043487 8 8 0,000 0,05227926 0,10185061 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05227926 0,10174306 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05227926 0,10163574 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05227926 0,10152864 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05227926 0,10142177 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05227926 0,10131512 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05227926 0,1012087 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05227926 0,1011025 ! developmental induction GO:0031128 8 8 0,000 0,05227926 0,10099652 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05227926 0,10089076 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05227926 0,10078523 ! actin filament polymerization GO:0030041 9 8 0,000 0,05227926 0,10067992 ! peptide hormone processing GO:0016486 8 8 0,000 0,05227926 0,10057482 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05227926 0,10046995 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05227926 0,10036529 ! reproductive developmental process GO:0003006 56 56 1,000 0,05361837 0,10282899 ! extracellular structure organization GO:0043062 56 56 1,000 0,05361837 0,1027221 ! lactation GO:0007595 10 9 0,000 0,05862314 0,11219362 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05862314 0,11207723 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05862314 0,11196109 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05862314 0,11184519 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05862314 0,11172953 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05862314 0,1116141 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,05862314 0,11149892 ! viral genome replication GO:0019079 9 9 0,000 0,05862314 0,11138397 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05862314 0,11126926 ! copper ion transport GO:0006825 9 9 0,000 0,05862314 0,11115479 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05862314 0,11104055 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05862314 0,11092654 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05862314 0,11081277 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05862314 0,11069923 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05862314 0,11058593 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05862314 0,11047286 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05862314 0,11036001 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05862314 0,1102474 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05862314 0,11013502 ! phospholipid efflux GO:0033700 9 9 0,000 0,05862314 0,11002286 ! response to alkaloid GO:0043279 10 9 0,000 0,05862314 0,10991094 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05862314 0,10979924 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05862314 0,10968777 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,05862314 0,10957652 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05862314 0,1094655 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05862314 0,10935471 ! response to ethanol GO:0045471 9 9 0,000 0,05862314 0,10924414 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,05862314 0,10913379 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05862314 0,10902367 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05862314 0,10891376 ! methionine metabolic process GO:0006555 9 9 0,000 0,05862314 0,10880408 ! cerebral cortex development GO:0021987 9 9 0,000 0,05862314 0,10869462 ! response to osmotic stress GO:0006970 9 9 0,000 0,05862314 0,10858538 ! pigmentation during development GO:0048066 9 9 0,000 0,05862314 0,10847636 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05862314 0,10836756 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05862314 0,10825897 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05862314 0,1081506 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05862314 0,10804245 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05862314 0,10793452 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05862314 0,1078268 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,05862314 0,10771929 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,05862314 0,107612 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05862314 0,10750493 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05862314 0,10739806 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05862314 0,10729141 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05862314 0,10718497 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05862314 0,10707874 ! DNA replication initiation GO:0006270 9 9 0,000 0,05862314 0,10697273 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05862314 0,10686692 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05862314 0,10676132 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05862314 0,10665593 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05862314 0,10655074 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05862314 0,10644577 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05862314 0,106341 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05862314 0,10623643 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05862314 0,10613208 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,05862314 0,10602792 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05862314 0,10592397 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,05862314 0,10582023 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05862314 0,10571669 ! collagen catabolic process GO:0030574 9 9 0,000 0,05862314 0,10561335 ! gas transport GO:0015669 9 9 0,000 0,05862314 0,10551021 ! cholesterol efflux GO:0033344 9 9 0,000 0,05862314 0,10540727 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05862314 0,10530453 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05862314 0,105202 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05862314 0,10509966 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05862314 0,10499752 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,05862314 0,10489559 ! defense response to virus GO:0051607 9 9 0,000 0,05862314 0,10479384 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05862314 0,1046923 ! actin filament-based movement GO:0030048 9 9 0,000 0,05862314 0,10459095 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05862314 0,1044898 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,0606074 0,10792217 ! protein polymerization GO:0051258 65 60 1,000 0,0606074 0,107818 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,06240157 0,1109027 GO:0016054|organic acid catabolic process, ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,06421388 0,11401366 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 1,000 0,06421388 0,11390392 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,06421388 0,1137944 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,06421388 0,11368509 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06492548 0,1148346 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06492548 0,1147245 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06492548 0,11461461 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06492548 0,11450493 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06492548 0,11439546 ! neuron maturation GO:0042551 10 10 0,000 0,06492548 0,1142862 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06492548 0,11417715 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06492548 0,11406831 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06492548 0,11395967 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06492548 0,11385124 ! hormone secretion GO:0046879 10 10 0,000 0,06492548 0,11374302 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06492548 0,113635 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06492548 0,11352719 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,06492548 0,11341958 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06492548 0,11331217 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06492548 0,11320497 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06492548 0,11309797 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06492548 0,11299117 ! glial cell development GO:0021782 10 10 0,000 0,06492548 0,11288458 ! centrosome cycle GO:0007098 10 10 0,000 0,06492548 0,11277818 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06492548 0,11267199 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06492548 0,112566 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06492548 0,1124602 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,06492548 0,1123546 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,06492548 0,11224921 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,06492548 0,11214401 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06492548 0,112039 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06492548 0,11193419 ! plasma membrane organization GO:0007009 10 10 0,000 0,06492548 0,11182958 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,06492548 0,11172517 ! lysosomal transport GO:0007041 10 10 0,000 0,06492548 0,11162095 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06492548 0,11151692 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06492548 0,11141309 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06492548 0,11130945 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06492548 0,111206 ! exocrine system development GO:0035272 10 10 0,000 0,06492548 0,11110274 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,06492548 0,11099968 ! embryo implantation GO:0007566 11 10 0,000 0,06492548 0,11089681 ! regulation of protein binding GO:0043393 11 10 0,000 0,06492548 0,11079412 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06492548 0,11069163 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06492548 0,11058933 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06492548 0,11048722 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,06492548 0,11038529 ! protein export from nucleus GO:0006611 10 10 0,000 0,06492548 0,11028355 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06492548 0,110182 ! cytolysis GO:0019835 10 10 0,000 0,06492548 0,11008064 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06492548 0,10997946 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06492548 0,10987847 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,06492548 0,10977766 ! histone deacetylation GO:0016575 10 10 0,000 0,06492548 0,10967704 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06492548 0,10957661 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06492548 0,10947635 ! gland morphogenesis GO:0022612 10 10 0,000 0,06492548 0,10937628 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06492548 0,1092764 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06492548 0,10917669 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06492548 0,10907717 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06492548 0,10897783 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,06492548 0,10887867 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06492548 0,10877969 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06492548 0,10868088 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06492548 0,10858226 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06492548 0,10848382 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06492548 0,10838556 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06492548 0,10828747 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,06492548 0,10818956 ! nerve development GO:0021675 10 10 0,000 0,06492548 0,10809183 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,06492548 0,10799427 ! gut development GO:0048565 10 10 0,000 0,06492548 0,10789689 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06492548 0,10779969 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,06492548 0,10770266 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06492548 0,1076058 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06492548 0,10750912 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,06789164 0,11231984 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,06789164 0,1122191 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,06975649 0,11519823 ! protein secretion GO:0009306 11 11 0,000 0,07118653 0,11745459 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07118653 0,11734953 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07118653 0,11724466 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07118653 0,11713998 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07118653 0,11703548 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07118653 0,11693117 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07118653 0,11682705 ! skin development GO:0043588 11 11 0,000 0,07118653 0,11672311 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07118653 0,11661935 ! microtubule-based transport GO:0010970 11 11 0,000 0,07118653 0,11651578 ! endothelial cell migration GO:0043542 11 11 0,000 0,07118653 0,1164124 ! peroxisomal transport GO:0043574 11 11 0,000 0,07118653 0,1163092 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07118653 0,11620618 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,07118653 0,11610334 GO:0003015|heart process, ! dendrite development GO:0016358 11 11 0,000 0,07118653 0,11600068 ! T cell proliferation GO:0042098 11 11 0,000 0,07118653 0,11589821 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07118653 0,11579592 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,07118653 0,1156938 ! spinal cord development GO:0021510 11 11 0,000 0,07118653 0,11559187 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07118653 0,11549012 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07118653 0,11538854 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07118653 0,11528715 ! digestive system process GO:0022600 11 11 0,000 0,07118653 0,11518593 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07118653 0,11508489 ! fucose metabolic process GO:0006004 11 11 0,000 0,07118653 0,11498403 ! membrane budding GO:0006900 11 11 0,000 0,07118653 0,11488334 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,07118653 0,11478283 ! monoamine transport GO:0015844 11 11 0,000 0,07118653 0,11468249 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07118653 0,11458233 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07118653 0,11448235 ! body fluid secretion GO:0007589 11 11 0,000 0,07118653 0,11438254 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07118653 0,1142829 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07118653 0,11418344 ! membrane depolarization GO:0051899 11 11 0,000 0,07118653 0,11408415 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07118653 0,11398503 ! oogenesis GO:0048477 11 11 0,000 0,07118653 0,11388609 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07118653 0,11378731 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07118653 0,11368871 ! vitamin transport GO:0051180 11 11 0,000 0,07118653 0,11359028 ! muscle maintenance GO:0046716 12 11 0,000 0,07118653 0,11349202 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07118653 0,11339393 ! hindbrain development GO:0030902 11 11 0,000 0,07118653 0,113296 ! steroid catabolic process GO:0006706 11 11 0,000 0,07118653 0,11319825 ! endocrine process GO:0050886 11 11 0,000 0,07118653 0,11310067 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07118653 0,11300325 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07118653 0,112906 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07118653 0,11280892 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,07353663 0,116433 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! muscle contraction GO:0006936 67 67 1,000 0,07353663 0,11633306 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,07545132 0,11925968 ! regulation of cell size GO:0008361 68 68 1,000 0,07545132 0,11915749 ! sensory perception of sound GO:0007605 71 69 1,000 0,07738204 0,12210197 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,07738204 0,12199752 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,07738204 0,12189325 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,07738204 0,12178915 ! translational initiation GO:0006413 12 12 0,000 0,07740656 0,1217238 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,07740656 0,12162003 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,07740656 0,12151644 ! initiation of viral infection GO:0019059 12 12 0,000 0,07740656 0,12141302 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,07740656 0,12130978 ! iron ion transport GO:0006826 13 12 0,000 0,07740656 0,12120671 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,07740656 0,12110382 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,07740656 0,1210011 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,07740656 0,12089856 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,07740656 0,12079619 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,07740656 0,12069399 ! collagen metabolic process GO:0032963 12 12 0,000 0,07740656 0,12059197 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,07740656 0,12049012 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,07740656 0,12038844 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,07740656 0,12028693 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,07740656 0,12018559 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,07740656 0,12008443 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,07740656 0,11998343 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,07740656 0,1198826 ! actomyosin structure organization GO:0031032 12 12 0,000 0,07740656 0,11978195 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,07740656 0,11968146 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,07740656 0,11958114 ! retinoid metabolic process GO:0001523 12 12 0,000 0,07740656 0,11948099 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,07740656 0,119381 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,07740656 0,11928118 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,07740656 0,11918153 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,07740656 0,11908205 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,07740656 0,11898273 ! vacuolar transport GO:0007034 12 12 0,000 0,07740656 0,11888358 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,07740656 0,11878459 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,07740656 0,11868577 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,07740656 0,11858711 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,07740656 0,11848862 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,07740656 0,11839029 ! male gonad development GO:0008584 12 12 0,000 0,07740656 0,11829212 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,07740656 0,11819412 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,07740656 0,11809627 ! renal system process GO:0003014 12 12 0,000 0,07740656 0,11799859 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,07740656 0,11790107 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,07740656 0,11780371 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,07740656 0,11770652 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,07740656 0,11760948 ! pallium development GO:0021543 13 12 0,000 0,07740656 0,1175126 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,07740656 0,11741588 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,07740656 0,11731932 ! G1 phase GO:0051318 13 12 0,000 0,07740656 0,11722292 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,07740656 0,11712668 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,07740656 0,1170306 ! synaptogenesis GO:0007416 12 12 0,000 0,07740656 0,11693467 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,07740656 0,1168389 ! hormone transport GO:0009914 12 12 0,000 0,07740656 0,11674329 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,07740656 0,11664783 ! heme biosynthetic process GO:0006783 12 12 0,000 0,07740656 0,11655253 ! spermatid differentiation GO:0048515 13 12 0,000 0,07740656 0,11645739 GO:0007286|spermatid development, ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,07740656 0,1163624 ! neural tube closure GO:0001843 13 12 0,000 0,07740656 0,11626756 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,07740656 0,11617288 ! negative regulation of translation GO:0017148 12 12 0,000 0,07740656 0,11607835 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,07740656 0,11598398 ! positive regulation of transport GO:0051050 71 70 1,000 0,07932849 0,11876719 ! cell part morphogenesis GO:0032990 75 70 1,000 0,07932849 0,11867079 ! translational elongation GO:0006414 71 71 1,000 0,0812904 0,12150706 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,0812904 0,12140859 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,0812904 0,12131029 ! regulation of cell activation GO:0050865 71 71 1,000 0,0812904 0,12121214 ! muscle system process GO:0003012 72 72 1,000 0,08326747 0,12405978 ! sensory organ development GO:0007423 72 72 1,000 0,08326747 0,12395957 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,08358584 0,1243331 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08358584 0,12423283 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08358584 0,12413272 ! phenol metabolic process GO:0018958 13 13 0,000 0,08358584 0,12403278 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,08358584 0,12393299 ! gluconeogenesis GO:0006094 13 13 0,000 0,08358584 0,12383337 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08358584 0,1237339 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08358584 0,1236346 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08358584 0,12353545 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08358584 0,12343647 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,08358584 0,12333764 ! regeneration GO:0031099 13 13 0,000 0,08358584 0,12323897 ! keratinization GO:0031424 13 13 0,000 0,08358584 0,12314046 ! post-embryonic development GO:0009791 14 13 0,000 0,08358584 0,1230421 ! patterning of blood vessels GO:0001569 13 13 0,000 0,08358584 0,1229439 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,08358584 0,12284586 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08358584 0,12274798 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08358584 0,12265025 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08358584 0,12255267 ! autophagy GO:0006914 13 13 0,000 0,08358584 0,12245526 ! actin filament bundle formation GO:0051017 13 13 0,000 0,08358584 0,12235799 ! ureteric bud development GO:0001657 13 13 0,000 0,08358584 0,12226088 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,08358584 0,12216393 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08358584 0,12206712 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08358584 0,12197048 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,08358584 0,12187398 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08358584 0,12177764 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08358584 0,12168145 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08358584 0,12158541 ! vasodilation GO:0042311 14 13 0,000 0,08358584 0,12148952 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08358584 0,12139378 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08358584 0,1212982 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,08358584 0,12120276 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,08358584 0,12110748 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08358584 0,12101234 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08358584 0,12091736 ! immunoglobulin production GO:0002377 13 13 0,000 0,08358584 0,12082252 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08358584 0,12072783 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08358584 0,12063329 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,08358584 0,1205389 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,08358584 0,12044465 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,08358584 0,12035056 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08358584 0,12025661 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08358584 0,1201628 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08358584 0,12006914 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08358584 0,11997563 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08358584 0,11988227 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08358584 0,11978904 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,08358584 0,11969597 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08358584 0,11960304 ! telomere organization GO:0032200 13 13 0,000 0,08358584 0,11951025 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08358584 0,11941761 ! regulation of amine transport GO:0051952 13 13 0,000 0,08358584 0,11932511 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,08928691 0,12736516 ! response to oxidative stress GO:0006979 76 75 1,000 0,08928691 0,12726665 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,08928691 0,1271683 ! neuron fate commitment GO:0048663 14 14 0,000 0,08972463 0,12769305 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08972463 0,12759452 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08972463 0,12749614 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08972463 0,12739792 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08972463 0,12729984 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08972463 0,12720192 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08972463 0,12710415 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08972463 0,12700653 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08972463 0,12690905 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08972463 0,12681173 ! vesicle docking GO:0048278 14 14 0,000 0,08972463 0,12671456 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08972463 0,12661753 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08972463 0,12652065 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08972463 0,12642393 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08972463 0,12632735 ! hair cycle GO:0042633 14 14 0,000 0,08972463 0,12623091 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08972463 0,12613463 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08972463 0,12603849 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,08972463 0,12594249 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08972463 0,12584665 ! lysosome organization GO:0007040 14 14 0,000 0,08972463 0,12575095 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08972463 0,12565539 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08972463 0,12555998 ! peptide transport GO:0015833 14 14 0,000 0,08972463 0,12546472 ! primary neural tube formation GO:0014020 15 14 0,000 0,08972463 0,12536959 ! peptide cross-linking GO:0018149 14 14 0,000 0,08972463 0,12527462 ! regulation of behavior GO:0050795 14 14 0,000 0,08972463 0,12517978 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08972463 0,1250851 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08972463 0,12499055 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08972463 0,12489614 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08972463 0,12480188 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08972463 0,12470776 ! collagen fibril organization GO:0030199 14 14 0,000 0,08972463 0,12461379 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08972463 0,12451995 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08972463 0,12442626 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08972463 0,1243327 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08972463 0,12423929 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08972463 0,12414602 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08972463 0,12405289 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,08972463 0,12395989 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08972463 0,12386704 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,09132189 0,12597773 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,09337066 0,12870765 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,09337066 0,12861146 ! microtubule-based movement GO:0007018 82 78 1,000 0,09543297 0,13135397 ! metal ion homeostasis GO:0055065 78 78 1,000 0,09543297 0,13125594 ! regulation of immune response GO:0050776 78 78 1,000 0,09543297 0,13115806 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,09582318 0,13159622 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09582318 0,13149823 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09582318 0,13140039 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09582318 0,1313027 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09582318 0,13120515 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09582318 0,13110774 ! response to vitamin GO:0033273 15 15 0,000 0,09582318 0,13101048 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,09582318 0,13091337 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,09582318 0,13081639 ! ovarian follicle development GO:0001541 15 15 0,000 0,09582318 0,13071956 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09582318 0,13062288 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09582318 0,13052633 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09582318 0,13042993 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09582318 0,13033367 ! heme metabolic process GO:0042168 15 15 0,000 0,09582318 0,13023756 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09582318 0,13014158 ! chromosome condensation GO:0030261 15 15 0,000 0,09582318 0,13004575 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09582318 0,12995006 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09582318 0,12985451 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09582318 0,1297591 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09582318 0,12966382 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09582318 0,12956869 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09582318 0,1294737 ! phospholipid transport GO:0015914 15 15 0,000 0,09582318 0,12937885 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,09582318 0,12928414 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09582318 0,12918956 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09582318 0,12909512 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09582318 0,12900083 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,09582318 0,12890666 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09582318 0,12881264 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09582318 0,12871875 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09582318 0,128625 ! neuron projection development GO:0031175 85 80 1,000 0,09959713 0,13359353 ! MAPKKK cascade GO:0000165 82 81 1,000 0,10169847 0,13631293 ! tube development GO:0035295 83 81 1,000 0,10169847 0,13621387 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10188176 0,13636027 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,10188176 0,13626131 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10188176 0,1361625 ! learning GO:0007612 16 16 0,000 0,10188176 0,13606383 ! circadian rhythm GO:0007623 16 16 0,000 0,10188176 0,13596531 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10188176 0,13586692 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,10188176 0,13576868 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,10188176 0,13567058 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,10188176 0,13557263 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10188176 0,13547481 ! vesicle targeting GO:0006903 17 16 0,000 0,10188176 0,13537714 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10188176 0,1352796 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,10188176 0,13518221 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10188176 0,13508496 ! positive regulation of cell development GO:0010720 16 16 0,000 0,10188176 0,13498784 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,10188176 0,13489087 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,10188176 0,13479403 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,10188176 0,13469734 ! cell fate specification GO:0001708 16 16 0,000 0,10188176 0,13460078 ! pentose metabolic process GO:0019321 16 16 0,000 0,10188176 0,13450436 ! fatty acid transport GO:0015908 16 16 0,000 0,10188176 0,13440808 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10188176 0,13431194 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,10188176 0,13421593 ! cofactor catabolic process GO:0051187 16 16 0,000 0,10188176 0,13412006 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10188176 0,13402433 ! polyol metabolic process GO:0019751 16 16 0,000 0,10188176 0,13392874 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10188176 0,13383328 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10188176 0,13373795 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10188176 0,13364277 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10188176 0,13354772 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,10188176 0,1334528 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,10188176 0,13335802 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,10593839 0,13856951 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,10790062 0,14103606 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,10790062 0,1409361 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,10790062 0,14083629 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,10790062 0,14073662 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,10790062 0,14063709 ! leukocyte adhesion GO:0007159 17 17 0,000 0,10790062 0,1405377 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,10790062 0,14043845 ! sensory perception of smell GO:0007608 17 17 0,000 0,10790062 0,14033934 ! glucose transport GO:0015758 17 17 0,000 0,10790062 0,14024037 ! cell junction assembly GO:0034329 18 17 0,000 0,10790062 0,14014154 ! tissue remodeling GO:0048771 17 17 0,000 0,10790062 0,14004285 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,10790062 0,13994429 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,10790062 0,13984588 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,10790062 0,13974761 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,10790062 0,13964947 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,10790062 0,13955147 ! neural crest cell development GO:0014032 19 17 0,000 0,10790062 0,13945361 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,10790062 0,13935588 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,10790062 0,13925829 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,10790062 0,13916084 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,10790062 0,13906353 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,10790062 0,13896635 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,10790062 0,1388693 ! pigmentation GO:0043473 17 17 0,000 0,10790062 0,1387724 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,10790062 0,13867562 ! adult locomotory behavior GO:0008344 17 17 0,000 0,10790062 0,13857898 ! embryonic organ development GO:0048568 17 17 0,000 0,10790062 0,13848248 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,10790062 0,13838611 ! liver development GO:0001889 17 17 0,000 0,10790062 0,13828988 ! gene silencing GO:0016458 17 17 0,000 0,10790062 0,13819377 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,11022629 0,14107435 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11388001 0,14564945 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11388001 0,14554845 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11388001 0,14544758 ! membrane docking GO:0022406 18 18 0,000 0,11388001 0,14534686 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,11388001 0,14524627 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,11388001 0,14514582 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,11388001 0,14504552 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11388001 0,14494535 ! hexose transport GO:0008645 18 18 0,000 0,11388001 0,14484532 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,11388001 0,14474542 GO:0055092|sterol homeostasis, ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,11388001 0,14464567 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,11388001 0,14454605 GO:0046519|sphingoid metabolic process, ! telencephalon development GO:0021537 19 18 0,000 0,11388001 0,14444657 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11388001 0,14434722 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,11388001 0,14424802 ! BMP signaling pathway GO:0030509 18 18 0,000 0,11388001 0,14414894 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,11388001 0,14405001 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,11388001 0,14395121 ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,11674386 0,14747014 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,11893828 0,15013921 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,11982019 0,15114895 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,11982019 0,15104556 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,11982019 0,15094232 ! feeding behavior GO:0007631 19 19 0,000 0,11982019 0,15083922 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,11982019 0,15073626 ! peroxisome organization GO:0007031 19 19 0,000 0,11982019 0,15063343 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,11982019 0,15053075 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,11982019 0,15042821 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,11982019 0,15032581 ! metanephros development GO:0001656 19 19 0,000 0,11982019 0,15022355 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,11982019 0,15012142 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,11982019 0,15001944 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,11982019 0,14991759 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,11982019 0,14981589 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,11982019 0,14971432 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,11982019 0,14961288 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,11982019 0,14951159 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,11982019 0,14941043 ! eye morphogenesis GO:0048592 19 19 0,000 0,11982019 0,14930941 ! regulation of cell shape GO:0008360 21 19 0,000 0,11982019 0,14920852 ! response to heat GO:0009408 19 19 0,000 0,11982019 0,14910778 ! vesicle localization GO:0051648 20 19 0,000 0,11982019 0,14900716 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,12335855 0,15330398 ! DNA replication GO:0006260 91 91 1,000 0,12335855 0,15320068 ! regulation of muscle development GO:0048634 21 20 0,000 0,12572141 0,15603001 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,12572141 0,15592501 ! organic ether metabolic process GO:0018904 20 20 0,000 0,12572141 0,15582015 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,12572141 0,15571543 ! neural tube development GO:0021915 21 20 0,000 0,12572141 0,15561086 ! nucleus organization GO:0006997 20 20 0,000 0,12572141 0,15550642 ! phagocytosis GO:0006909 21 20 0,000 0,12572141 0,15540212 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,12572141 0,15529797 ! protein targeting to membrane GO:0006612 22 20 0,000 0,12572141 0,15519395 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,12572141 0,15509007 ! chromatin remodeling GO:0006338 20 20 0,000 0,12572141 0,15498633 ! lipid oxidation GO:0034440 20 20 0,000 0,12572141 0,15488273 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,12572141 0,15477927 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,12572141 0,15467594 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,12572141 0,15457276 ! RNA modification GO:0009451 20 20 0,000 0,12572141 0,15446971 ! single fertilization GO:0007338 21 20 0,000 0,12572141 0,1543668 ! regulation of B cell activation GO:0050864 20 20 0,000 0,12572141 0,15426402 ! regulation of response to stress GO:0080134 97 94 1,000 0,13006414 0,1594865 ! pattern specification process GO:0007389 96 94 1,000 0,13006414 0,15938045 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,13158392 0,16113566 ! mRNA catabolic process GO:0006402 21 21 0,000 0,13158392 0,16102866 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,13158392 0,16092181 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,13158392 0,1608151 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,13158392 0,16070853 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,13158392 0,1606021 ! ear morphogenesis GO:0042471 21 21 0,000 0,13158392 0,16049581 ! organic anion transport GO:0015711 21 21 0,000 0,13158392 0,16038966 ! cholesterol transport GO:0030301 21 21 0,000 0,13158392 0,16028365 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,13158392 0,16017779 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,13158392 0,16007206 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,13158392 0,15996647 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,13158392 0,15986102 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,13158392 0,15975571 ! regulation of proteolysis GO:0030162 21 21 0,000 0,13158392 0,15965054 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,13158392 0,15954551 ! RNA export from nucleus GO:0006405 22 22 0,000 0,13740797 0,16649763 ! sister chromatid segregation GO:0000819 22 22 0,000 0,13740797 0,16638823 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,13740797 0,16627898 ! regulation of ion transport GO:0043269 22 22 0,000 0,13740797 0,16616987 ! odontogenesis GO:0042476 22 22 0,000 0,13740797 0,16606091 ! cell junction organization GO:0034330 23 22 0,000 0,13740797 0,16595209 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,13740797 0,16584341 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,13740797 0,16573487 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,13740797 0,16562648 ! ovulation cycle process GO:0022602 22 22 0,000 0,13740797 0,16551823 ! cell chemotaxis GO:0060326 23 22 0,000 0,13740797 0,16541012 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,13740797 0,16530215 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,13740797 0,16519432 ! male sex differentiation GO:0046661 22 22 0,000 0,13740797 0,16508663 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,13740797 0,16497908 ! biopolymer methylation GO:0043414 22 22 0,000 0,13740797 0,16487167 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,13740797 0,1647644 ! neuron migration GO:0001764 22 22 0,000 0,13740797 0,16465727 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,13740797 0,16455028 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,13740797 0,16444343 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,13740797 0,16433672 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,13740797 0,16423015 ! aerobic respiration GO:0009060 22 22 0,000 0,13740797 0,16412371 ! cytokine production GO:0001816 22 22 0,000 0,13740797 0,16401741 ! cytokinesis GO:0000910 23 22 0,000 0,13740797 0,16391125 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,13740797 0,16380523 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,13913589 0,16575789 ! regulation of system process GO:0044057 98 98 1,000 0,13913589 0,16565081 ! anti-apoptosis GO:0006916 100 99 1,000 0,14142578 0,16826838 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,1431938 0,17026205 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,1431938 0,17015227 ! viral infectious cycle GO:0019058 23 23 0,000 0,1431938 0,17004264 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,1431938 0,16993315 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,1431938 0,16982379 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,1431938 0,16971458 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,1431938 0,16960551 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,1431938 0,16949658 ! endocrine system development GO:0035270 23 23 0,000 0,1431938 0,16938779 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,1431938 0,16927914 ! female gonad development GO:0008585 23 23 0,000 0,1431938 0,16917063 ! lipid homeostasis GO:0055088 23 23 0,000 0,1431938 0,16906225 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,1431938 0,16895402 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,1431938 0,16884592 ! gliogenesis GO:0042063 24 24 0,000 0,14894166 0,17551118 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,14894166 0,17539903 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,14894166 0,17528703 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,14894166 0,17517517 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,14894166 0,17506345 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,14894166 0,17495187 ! ovulation cycle GO:0042698 24 24 0,000 0,14894166 0,17484044 ! fertilization GO:0009566 25 24 0,000 0,14894166 0,17472914 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,14894166 0,17461799 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,14894166 0,17450698 ! glucan metabolic process GO:0044042 25 24 0,000 0,14894166 0,17439611 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,1546518 0,18096715 ! negative regulation of secretion GO:0051048 26 25 0,000 0,1546518 0,18085232 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,1546518 0,18073764 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,1546518 0,18062311 ! cellular component disassembly GO:0022411 26 25 0,000 0,1546518 0,18050872 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,1546518 0,18039447 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,1546518 0,18028037 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,1546518 0,18016641 ! excretion GO:0007588 25 25 0,000 0,1546518 0,1800526 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,1546518 0,17993893 ! gastrulation GO:0007369 25 25 0,000 0,1546518 0,1798254 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,1546518 0,17971202 ! regulation of endocytosis GO:0030100 25 25 0,000 0,1546518 0,17959878 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,1546518 0,17948568 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,1546518 0,17937273 ! positive regulation of defense response GO:0031349 26 26 0,000 0,16032445 0,18583519 ! glycolysis GO:0006096 26 26 0,000 0,16032445 0,18571839 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,16032445 0,18560173 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,16032445 0,18548522 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,16032445 0,18536886 ! cellular defense response GO:0006968 26 26 0,000 0,16032445 0,18525264 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,16032445 0,18513656 ! regulation of protein secretion GO:0050708 26 26 0,000 0,16032445 0,18502064 ! germ cell development GO:0007281 27 26 0,000 0,16032445 0,18490485 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,16032445 0,18478922 GO:0035150|regulation of tube size, ! chloride transport GO:0006821 27 27 0,000 0,16595985 0,19116501 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,16595985 0,1910456 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,16595985 0,19092635 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,16595985 0,19080724 ! peptide metabolic process GO:0006518 29 27 0,000 0,16595985 0,19068829 ! mesenchymal cell development GO:0014031 29 27 0,000 0,16595985 0,19056948 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! defense response to bacterium GO:0042742 27 27 0,000 0,16595985 0,19045082 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,16595985 0,1903323 ! cell growth GO:0016049 27 27 0,000 0,16595985 0,19021394 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,17155826 0,19650831 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,17155826 0,19638625 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,17155826 0,19626435 ! carbohydrate transport GO:0008643 28 28 0,000 0,17155826 0,1961426 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,17155826 0,196021 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,17155826 0,19589954 ! developmental growth GO:0048589 28 28 0,000 0,17155826 0,19577824 ! cartilage development GO:0051216 29 28 0,000 0,17155826 0,19565709 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,17711989 0,20187505 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,17711989 0,20175028 ! leukocyte migration GO:0050900 30 29 0,000 0,17711989 0,20162567 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,17711989 0,20150121 ! antigen processing and presentation GO:0019882 29 29 0,000 0,17711989 0,2013769 ! tRNA processing GO:0008033 29 29 0,000 0,17711989 0,20125275 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,17711989 0,20112875 ! adult behavior GO:0030534 30 29 0,000 0,17711989 0,2010049 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,17711989 0,2008812 ! transition metal ion transport GO:0000041 31 30 0,000 0,18264499 0,20702013 ! RNA catabolic process GO:0006401 30 30 0,000 0,18264499 0,20689288 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,18264499 0,2067658 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,18264499 0,20663887 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,18264499 0,2065121 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,18264499 0,20638548 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,18264499 0,20625902 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,18264499 0,20613272 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,18264499 0,20600656 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,18264499 0,20588057 ! response to temperature stimulus GO:0009266 30 30 0,000 0,18264499 0,20575472 ! regulation of ossification GO:0030278 30 30 0,000 0,18264499 0,20562903 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,18264499 0,20550349 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,18264499 0,20537811 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,18264499 0,20525288 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,18264499 0,2051278 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,18264499 0,20500288 ! regulation of translational initiation GO:0006446 31 31 0,000 0,1881338 0,21103506 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,1881338 0,21090669 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,1881338 0,21077848 ! ion transmembrane transport GO:0034220 31 31 0,000 0,1881338 0,21065042 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,1881338 0,21052252 ! digestion GO:0007586 31 31 0,000 0,1881338 0,21039478 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,1881338 0,21026719 ! regulation of heart contraction GO:0008016 31 31 0,000 0,1881338 0,21013976 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,1881338 0,21001247 ! camera-type eye development GO:0043010 31 31 0,000 0,1881338 0,20988535 ! extracellular matrix organization GO:0030198 31 31 0,000 0,1881338 0,20975838 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,1881338 0,20963156 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,1881338 0,20950489 ! cell redox homeostasis GO:0045454 32 32 0,000 0,19358655 0,21544686 ! glucose catabolic process GO:0006007 32 32 0,000 0,19358655 0,21531684 ! lipid modification GO:0030258 32 32 0,000 0,19358655 0,21518697 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,19358655 0,21505727 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,19358655 0,21492771 ! cell maturation GO:0048469 32 32 0,000 0,19358655 0,21479832 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,19358655 0,21466908 ! nuclear export GO:0051168 32 32 0,000 0,19358655 0,21453999 ! kidney development GO:0001822 32 32 0,000 0,19358655 0,21441106 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,19900346 0,2202783 ! amino acid transport GO:0006865 33 33 0,000 0,19900346 0,22014608 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,19900346 0,22001402 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,19900346 0,21988212 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,19900346 0,21975037 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,19900346 0,21961879 ! regulation of actin filament length GO:0030832 34 34 0,000 0,20438477 0,22542258 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,20438477 0,22528776 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,20438477 0,2251531 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,20438477 0,2250186 ! secondary metabolic process GO:0019748 34 34 0,000 0,20438477 0,22488426 ! acute inflammatory response GO:0002526 35 35 0,000 0,20973071 0,2306287 ! regulation of cellular component size GO:0032535 35 35 0,000 0,20973071 0,23049117 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,20973071 0,23035381 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,20973071 0,23021662 ! inorganic anion transport GO:0015698 35 35 0,000 0,20973071 0,23007958 ! regulation of immune effector process GO:0002697 35 35 0,000 0,20973071 0,22994271 ! hydrogen transport GO:0006818 36 36 0,000 0,2150415 0,23562514 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,2150415 0,23548514 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,2150415 0,2353453 ! regulation of mitosis GO:0007088 37 36 0,000 0,2150415 0,23520563 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,2150415 0,23506613 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,2150415 0,23492679 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,2150415 0,23478761 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,2150415 0,2346486 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,2150415 0,23450976 ! gonad development GO:0008406 36 36 0,000 0,2150415 0,23437108 ! activation of immune response GO:0002253 36 36 0,000 0,2150415 0,23423256 ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,22031738 0,23983752 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,22031738 0,23969594 ! eye development GO:0001654 37 37 0,000 0,22031738 0,23955453 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,22031738 0,23941328 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! adaptive immune response GO:0002250 37 37 0,000 0,22031738 0,2392722 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,22555856 0,24482004 ! neurotransmitter transport GO:0006836 40 38 0,000 0,22555856 0,24467594 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,22555856 0,24453202 ! exocytosis GO:0006887 40 38 0,000 0,22555856 0,24438826 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,22555856 0,24424467 ! urogenital system development GO:0001655 38 38 0,000 0,22555856 0,24410125 ! hexose catabolic process GO:0019320 38 38 0,000 0,22555856 0,243958 ! RNA elongation GO:0006354 38 38 0,000 0,22555856 0,24381491 ! regulation of neurological system process GO:0031644 38 38 0,000 0,22555856 0,243672 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,22555856 0,24352925 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,23076527 0,24900491 ! response to unfolded protein GO:0006986 39 39 0,000 0,23076527 0,24885921 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,23076527 0,24871368 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,23076527 0,24856832 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,23076527 0,24842313 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,23076527 0,2482781 ! developmental maturation GO:0021700 39 39 0,000 0,23076527 0,24813325 ! limb development GO:0060173 39 39 0,000 0,23076527 0,24798857 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,23593773 0,25339932 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,23593773 0,25325174 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,24107616 0,25861663 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,24107616 0,25846618 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,24107616 0,25831591 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,24107616 0,25816581 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,24618078 0,2634792 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,24618078 0,26332628 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,24618078 0,26317354 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,24618078 0,26302097 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,24618078 0,26286858 ! forebrain development GO:0030900 43 42 0,000 0,24618078 0,26271637 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,24618078 0,26256434 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,24618078 0,26241248 ! reproductive structure development GO:0048608 43 43 0,000 0,25125181 0,26766305 ! alcohol catabolic process GO:0046164 43 43 0,000 0,25125181 0,26750842 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,25125181 0,26735397 ! humoral immune response GO:0006959 44 44 0,000 0,25628946 0,27255711 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,25628946 0,27239993 ! mRNA transport GO:0051028 44 44 0,000 0,25628946 0,27224292 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,25628946 0,2720861 ! vitamin metabolic process GO:0006766 44 44 0,000 0,25628946 0,27192946 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,25628946 0,271773 ! amine biosynthetic process GO:0009309 46 45 0,000 0,26129395 0,2769205 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,26129395 0,27676135 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,26129395 0,27660238 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,26129395 0,2764436 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,26129395 0,27628499 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,26626549 0,28138033 ! tube morphogenesis GO:0035239 47 46 0,000 0,26626549 0,28121908 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,26626549 0,28105801 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,26626549 0,28089713 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,26626549 0,28073644 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,27120429 0,28578016 ! regulation of blood pressure GO:0008217 48 47 0,000 0,27120429 0,28561686 ! sex differentiation GO:0007548 47 47 0,000 0,27120429 0,28545375 ! amine transport GO:0015837 47 47 0,000 0,27120429 0,28529081 ! rhythmic process GO:0048511 47 47 0,000 0,27120429 0,28512807 ! calcium ion transport GO:0006816 48 48 0,000 0,27611057 0,29012074 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,27611057 0,28995543 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,27611057 0,28979031 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,27611057 0,28962537 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,28098453 0,29457025 ! divalent metal ion transport GO:0070838 49 49 0,000 0,28098453 0,29440278 ! response to nutrient GO:0007584 49 49 0,000 0,28098453 0,29423551 ! response to bacterium GO:0009617 50 49 0,000 0,28098453 0,29406842 ! regulation of ligase activity GO:0051340 50 49 0,000 0,28098453 0,29390153 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,28098453 0,29373482 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,28098453 0,29356831 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,28582639 0,29845781 ! chromatin assembly GO:0031497 50 50 0,000 0,28582639 0,29828881 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,28582639 0,29812 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! transcription initiation GO:0006352 50 50 0,000 0,28582639 0,29795138 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,29063634 0,30279411 ! positive regulation of immune response GO:0050778 51 51 0,000 0,29063634 0,30262304 ! rRNA metabolic process GO:0016072 51 51 0,000 0,29063634 0,30245216 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,29063634 0,30228148 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,29063634 0,30211099 ! RNA localization GO:0006403 52 52 0,000 0,2954146 0,3069048 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,2954146 0,30673189 ! sodium ion transport GO:0006814 53 53 0,000 0,30016137 0,31148502 ! tRNA metabolic process GO:0006399 53 53 0,000 0,30016137 0,31130974 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,30016137 0,31113465 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,30016137 0,31095975 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,30016137 0,31078506 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,30487685 0,31549019 ! response to virus GO:0009615 54 54 0,000 0,30487685 0,31531315 ! hormone metabolic process GO:0042445 55 54 0,000 0,30487685 0,3151363 ! sulfur metabolic process GO:0006790 55 54 0,000 0,30487685 0,31495966 ! nucleosome organization GO:0034728 55 55 0,000 0,30956124 0,31961981 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,30956124 0,31944085 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,31421475 0,32406143 ! ATP metabolic process GO:0046034 57 57 0,000 0,31883757 0,32864521 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,31883757 0,32846151 ! innate immune response GO:0045087 58 58 0,000 0,3234299 0,33300631 ! dephosphorylation GO:0016311 60 59 0,000 0,32799193 0,33751487 ! carboxylic acid transport GO:0046942 59 59 0,000 0,32799193 0,33732653 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,32799193 0,33713839 ! immune effector process GO:0002252 59 59 0,000 0,32799193 0,33695047 ! potassium ion transport GO:0006813 60 60 0,000 0,33252388 0,34141588 ! cellular respiration GO:0045333 62 61 0,000 0,33702591 0,34584563 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,33702591 0,34565318 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,33702591 0,34546093 ! lipid transport GO:0006869 62 62 0,000 0,34149824 0,34985062 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,34149824 0,34965626 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,34149824 0,34946211 ! regulation of secretion GO:0051046 65 63 0,000 0,34594105 0,35381208 ! glucose metabolic process GO:0006006 63 63 0,000 0,34594105 0,35361584 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,34594105 0,35341982 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,34594105 0,35322402 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,35035454 0,35753234 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,35035454 0,35733448 ! anion transport GO:0006820 65 65 0,000 0,35473888 0,36160606 ! regulation of hormone levels GO:0010817 66 65 0,000 0,35473888 0,36140617 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,35909427 0,3656413 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,35909427 0,3654394 ! DNA packaging GO:0006323 66 66 0,000 0,35909427 0,36523772 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,35909427 0,36503626 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,36342091 0,36923083 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,36342091 0,3690274 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,36771896 0,37318615 ! regulation of translation GO:0006417 69 69 0,000 0,37198862 0,37731152 ! growth GO:0040007 70 70 0,000 0,37623007 0,38140375 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,37623007 0,38119407 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,38044349 0,3852513 ! ribosome biogenesis GO:0042254 71 71 0,000 0,38044349 0,38503974 ! secretion by cell GO:0032940 75 72 0,000 0,38462907 0,38906223 ! regulation of cytokine production GO:0001817 72 72 0,000 0,38462907 0,38884881 ! electron transport chain GO:0022900 75 74 0,000 0,39291741 0,3970103 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,39291741 0,39679276 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,4010965 0,4048307 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,41713259 0,42078564 ! lipid catabolic process GO:0016042 82 81 0,000 0,42107552 0,42453074 ! ncRNA processing GO:0034470 83 83 0,000 0,42888325 0,43216612 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,43274839 0,43582256 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,43658794 0,43944925 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,44040207 0,4430464 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,44040207 0,4428047 ! male gamete generation GO:0048232 90 88 0,000 0,44795468 0,45015293 GO:0007283|spermatogenesis, ! chemotaxis GO:0006935 90 89 0,000 0,45169351 0,45366274 GO:0042330|taxis, ! brain development GO:0007420 91 90 0,000 0,45540755 0,45714386 ! fatty acid metabolic process GO:0006631 93 92 0,000 0,46276197 0,46427344 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,46276197 0,46402084 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,46276197 0,46376852 ! cofactor metabolic process GO:0051186 95 94 0,000 0,47001919 0,47078553 ! endocytosis GO:0006897 99 98 0,000 0,48424709 0,48477316 GO:0010324|membrane invagination, ! blood circulation GO:0008015 99 98 0,000 0,48424709 0,48450998 GO:0003013|circulatory system process, ! response to other organism GO:0051707 101 100 0,000 0,49122023 0,49122023