pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6110-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Notch receptor processing GO:0007220 8 5 3,000 4,878E-09 1,174E-05 ! amyloid precursor protein catabolic process GO:0042987 11 7 3,000 3,385E-08 4,072E-05 ! amyloid precursor protein metabolic process GO:0042982 14 9 3,000 1,208E-07 9,686E-05 ! Notch signaling pathway GO:0007219 96 48 5,000 2,985E-07 1,796E-04 ! regulation of cell projection assembly GO:0060491 30 12 3,000 4,682E-07 2,253E-04 ! membrane protein proteolysis GO:0033619 25 12 3,000 4,682E-07 1,878E-04 GO:0006509|membrane protein ectodomain proteolysis, ! glycoprotein catabolic process GO:0006516 26 15 3,000 1,274E-06 4,38E-04 ! nuclear migration GO:0007097 12 6 2,000 3,49E-06 1,05E-03 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 3,49E-06 9,331E-04 GO:0031272|regulation of pseudopodium assembly, ! protein oligomerization GO:0051259 139 78 5,000 5,433E-06 1,307E-03 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 6,083E-06 1,33E-03 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 2,000 6,083E-06 1,22E-03 ! macrophage differentiation GO:0030225 11 7 2,000 6,083E-06 1,126E-03 ! regulation of cell projection organization GO:0031344 121 50 4,000 9,32E-06 1,602E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 9,692E-06 1,555E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 9,692E-06 1,457E-03 ! establishment of nucleus localization GO:0040023 16 8 2,000 9,692E-06 1,372E-03 ! nucleoside diphosphate metabolic process GO:0009132 13 9 2,000 1,448E-05 1,935E-03 ! aging GO:0007568 103 55 4,000 1,496E-05 1,894E-03 ! positive regulation of cell projection organization GO:0031346 58 27 3,000 1,554E-05 1,869E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,784E-05 2,044E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 2,06E-05 2,252E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 2,295E-05 2,401E-03 ! nucleus localization GO:0051647 19 11 2,000 2,82E-05 2,827E-03 ! regulation of ARF GTPase activity GO:0032312 65 32 3,000 3,115E-05 2,997E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 3,745E-05 3,465E-03 GO:0042130|negative regulation of T cell proliferation, ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 3,000 3,981E-05 3,548E-03 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 4,848E-05 4,166E-03 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 25 13 2,000 4,848E-05 4,022E-03 ! response to gamma radiation GO:0010332 28 14 2,000 6,144E-05 4,928E-03 ! response to steroid hormone stimulus GO:0048545 137 78 4,000 8,176E-05 6,345E-03 ! filopodium assembly GO:0046847 32 16 2,000 9,374E-05 7,048E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 9,374E-05 6,835E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,018E-04 7,207E-03 ! double-strand break repair GO:0006302 81 44 3,000 1,115E-04 7,667E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,134E-04 7,576E-03 ! microspike assembly GO:0030035 36 17 2,000 1,134E-04 7,372E-03 ! regulation of ARF protein signal transduction GO:0032012 102 48 3,000 1,571E-04 9,946E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,877E-04 0,01157924 ! cellular response to starvation GO:0009267 33 20 2,000 1,877E-04 0,01128976 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,877E-04 0,0110144 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,877E-04 0,01075215 ! response to estrogen stimulus GO:0043627 93 51 3,000 1,991E-04 0,01114065 ! cell aging GO:0007569 44 21 2,000 2,181E-04 0,0119244 ! leukocyte differentiation GO:0002521 202 96 4,000 2,182E-04 0,01166394 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 2,29E-04 0,01197611 ! response to UV GO:0009411 104 53 3,000 2,313E-04 0,01183896 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,515E-04 0,0126042 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 2,515E-04 0,01234697 ! deoxyribonucleotide metabolic process GO:0009262 32 22 2,000 2,515E-04 0,01210003 ! cell cycle arrest GO:0007050 213 100 4,000 2,639E-04 0,01244882 ! regulation of DNA replication GO:0006275 101 56 3,000 2,863E-04 0,01324639 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,88E-04 0,01307306 ! sex determination GO:0007530 47 23 2,000 2,88E-04 0,01283096 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,132E-04 0,01370273 ! protein maturation by protein folding GO:0022417 13 5 1,000 3,132E-04 0,01345804 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,132E-04 0,01322193 ! parathyroid gland development GO:0060017 13 5 1,000 3,132E-04 0,01299397 ! microvillus organization GO:0032528 7 5 1,000 3,132E-04 0,01277373 GO:0030033|microvillus assembly, ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 3,132E-04 0,01256084 GO:0051489|regulation of filopodium assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 3,132E-04 0,01235492 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,132E-04 0,01215565 ! cellular glucose homeostasis GO:0001678 5 5 1,000 3,132E-04 0,0119627 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,132E-04 0,01177579 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 3,132E-04 0,01159462 ! decidualization GO:0046697 11 5 1,000 3,132E-04 0,01141894 ! mitotic recombination GO:0006312 9 5 1,000 3,132E-04 0,01124851 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 1,000 3,132E-04 0,01108309 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 3,132E-04 0,01092247 ! stem cell division GO:0017145 11 5 1,000 3,132E-04 0,01076643 GO:0048103|somatic stem cell division, ! protein import into nucleus, translocation GO:0000060 46 24 2,000 3,278E-04 0,01110672 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 3,278E-04 0,01095246 ! protein tetramerization GO:0051262 52 24 2,000 3,278E-04 0,01080242 ! vasculogenesis GO:0001570 46 25 2,000 3,709E-04 0,0120595 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 3,709E-04 0,01189871 ! negative regulation of DNA replication GO:0008156 42 25 2,000 3,709E-04 0,01174215 ! response to starvation GO:0042594 42 25 2,000 3,709E-04 0,01158965 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 3,709E-04 0,01144107 ! negative regulation of cell development GO:0010721 73 25 2,000 3,709E-04 0,01129624 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 2,000 3,709E-04 0,01115504 ! cellular response to nutrient levels GO:0031669 41 25 2,000 3,709E-04 0,01101732 ! kidney development GO:0001822 122 60 3,000 3,735E-04 0,01095876 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,176E-04 0,01210399 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 4,176E-04 0,0119599 GO:0045936|negative regulation of phosphate metabolic process, ! blastocyst development GO:0001824 49 26 2,000 4,176E-04 0,01181919 ! neuron fate commitment GO:0048663 48 27 2,000 4,678E-04 0,01308764 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 4,678E-04 0,01293721 ! male meiosis GO:0007140 7 6 1,000 4,681E-04 0,0127986 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 1,000 4,681E-04 0,01265479 ! protein refolding GO:0042026 15 6 1,000 4,681E-04 0,01251418 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 4,681E-04 0,01237667 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! urea metabolic process GO:0019627 7 6 1,000 4,681E-04 0,01224214 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! male sex determination GO:0030238 15 6 1,000 4,681E-04 0,0121105 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 4,681E-04 0,01198167 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 4,681E-04 0,01185554 ! purine base biosynthetic process GO:0009113 17 6 1,000 4,681E-04 0,01173205 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,681E-04 0,0116111 ! maternal placenta development GO:0001893 12 6 1,000 4,681E-04 0,01149262 ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,681E-04 0,01137653 ! positive regulation of cell motion GO:0051272 146 64 3,000 4,782E-04 0,01150549 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 5,218E-04 0,01242961 ! cell projection assembly GO:0030031 120 66 3,000 5,377E-04 0,01268352 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 5,796E-04 0,01353841 ! response to organic cyclic substance GO:0014070 55 29 2,000 5,796E-04 0,01340824 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 5,796E-04 0,01328054 ! protein maturation by peptide bond cleavage GO:0051605 105 68 3,000 6,023E-04 0,01367091 ! urogenital system development GO:0001655 137 69 3,000 6,366E-04 0,01431383 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 6,413E-04 0,01428699 ! regulation of helicase activity GO:0051095 15 7 1,000 6,529E-04 0,01441223 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 6,529E-04 0,01428121 ! SMAD protein complex assembly GO:0007183 12 7 1,000 6,529E-04 0,01415255 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,529E-04 0,01402619 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,529E-04 0,01390207 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 6,529E-04 0,01378012 ! vesicle fusion GO:0006906 17 7 1,000 6,529E-04 0,01366029 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 6,529E-04 0,01354253 ! centrosome duplication GO:0051298 13 7 1,000 6,529E-04 0,01342678 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,529E-04 0,013313 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 1,000 6,529E-04 0,01320112 ! B cell lineage commitment GO:0002326 21 7 1,000 6,529E-04 0,01309111 ! T cell lineage commitment GO:0002360 16 7 1,000 6,529E-04 0,01298292 ! response to tumor cell GO:0002347 13 7 1,000 6,529E-04 0,0128765 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,529E-04 0,01277182 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 7,071E-04 0,01371983 GO:0043433|negative regulation of transcription factor activity, ! metanephros development GO:0001656 74 32 2,000 7,77E-04 0,014956 ! response to ionizing radiation GO:0010212 65 32 2,000 7,77E-04 0,0148373 ! positive regulation of catabolic process GO:0009896 64 32 2,000 7,77E-04 0,01472047 ! regulation of transcription factor activity GO:0051090 126 74 3,000 8,289E-04 0,01558139 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 3,000 8,289E-04 0,01546061 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein transport GO:0051224 69 33 2,000 8,512E-04 0,01575354 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 8,673E-04 0,01592981 ! endothelial cell differentiation GO:0045446 17 8 1,000 8,673E-04 0,01580913 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 8,673E-04 0,01569027 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 8,673E-04 0,01557317 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 1,000 8,673E-04 0,01545782 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,673E-04 0,01534416 ! blastocyst growth GO:0001832 19 8 1,000 8,673E-04 0,01523216 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 8,673E-04 0,01512178 ! meiotic cell cycle GO:0051321 122 75 3,000 8,718E-04 0,01509062 ! regulation of catabolic process GO:0009894 161 76 3,000 9,162E-04 0,01574627 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,013E-03 0,01728008 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 1,013E-03 0,01715839 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 1,013E-03 0,0170384 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,1E-03 0,01838213 ! protein import into nucleus GO:0006606 158 80 3,000 1,11E-03 0,01841729 ! regulation of developmental growth GO:0048638 15 9 1,000 1,111E-03 0,01830879 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,111E-03 0,01818424 ! regulation of glycolysis GO:0006110 21 9 1,000 1,111E-03 0,01806137 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,111E-03 0,01794016 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,111E-03 0,01782056 ! receptor clustering GO:0043113 18 9 1,000 1,111E-03 0,01770254 ! purine base metabolic process GO:0006144 21 9 1,000 1,111E-03 0,01758608 ! artery development GO:0060840 24 9 1,000 1,111E-03 0,01747113 GO:0048844|artery morphogenesis, ! middle ear morphogenesis GO:0042474 14 9 1,000 1,111E-03 0,01735768 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 1,111E-03 0,0172457 ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 1,111E-03 0,01713515 ! motor axon guidance GO:0008045 16 9 1,000 1,111E-03 0,01702601 ! protein heterooligomerization GO:0051291 16 9 1,000 1,111E-03 0,01691825 ! T cell activation GO:0042110 168 81 3,000 1,163E-03 0,0175912 ! nuclear import GO:0051170 161 81 3,000 1,163E-03 0,01748125 ! regulation of neuron differentiation GO:0045664 167 81 3,000 1,163E-03 0,01737267 ! meiosis I GO:0007127 65 37 2,000 1,192E-03 0,01770808 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,192E-03 0,01759944 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,192E-03 0,01749212 ! regulation of protein stability GO:0031647 73 37 2,000 1,192E-03 0,01738611 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,192E-03 0,01728138 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,217E-03 0,01753074 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,289E-03 0,01846284 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,289E-03 0,01835359 GO:0042593|glucose homeostasis, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,384E-03 0,01958215 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,384E-03 0,01946764 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,384E-03 0,01935445 ! pathogenesis GO:0009405 13 10 1,000 1,384E-03 0,01924258 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,384E-03 0,01913199 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 1,384E-03 0,01902266 ! nucleobase biosynthetic process GO:0046112 24 10 1,000 1,384E-03 0,01891458 ! multicellular organism growth GO:0035264 18 10 1,000 1,384E-03 0,01880772 ! negative regulation of axonogenesis GO:0050771 32 10 1,000 1,384E-03 0,01870206 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 1,000 1,384E-03 0,01859758 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 1,000 1,384E-03 0,01849426 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,384E-03 0,01839208 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,384E-03 0,01829102 ! blastocyst formation GO:0001825 17 10 1,000 1,384E-03 0,01819107 ! localization within membrane GO:0051668 20 10 1,000 1,384E-03 0,01809221 ! mammary gland development GO:0030879 86 39 2,000 1,391E-03 0,01808857 ! negative regulation of binding GO:0051100 72 40 2,000 1,497E-03 0,01936993 ! protein localization in nucleus GO:0034504 176 87 3,000 1,515E-03 0,01949416 ! regulation of DNA binding GO:0051101 155 88 3,000 1,58E-03 0,02022546 ! gland development GO:0048732 206 88 3,000 1,58E-03 0,02011845 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,609E-03 0,02037487 ! T cell differentiation GO:0030217 81 41 2,000 1,609E-03 0,0202682 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,609E-03 0,02016263 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,685E-03 0,02100341 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,685E-03 0,02089514 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,685E-03 0,02078799 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,685E-03 0,02068193 ! regulation of lipoprotein lipase activity GO:0051004 23 11 1,000 1,685E-03 0,02057694 ! oocyte differentiation GO:0009994 18 11 1,000 1,685E-03 0,02047302 ! thymus development GO:0048538 27 11 1,000 1,685E-03 0,02037014 ! germ cell migration GO:0008354 25 11 1,000 1,685E-03 0,02026829 ! regulation of embryonic development GO:0045995 27 11 1,000 1,685E-03 0,02016745 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,726E-03 0,02055367 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 2,000 1,847E-03 0,02189583 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,936E-03 0,022835 ! JAK-STAT cascade GO:0007259 71 44 2,000 1,974E-03 0,02317293 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 2,014E-03 0,02352607 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,014E-03 0,02341242 ! virus-host interaction GO:0019048 29 12 1,000 2,014E-03 0,02329986 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,014E-03 0,02318838 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,014E-03 0,02307796 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,014E-03 0,02296858 ! positive regulation of cell growth GO:0030307 22 12 1,000 2,014E-03 0,02286024 ! tyrosine metabolic process GO:0006570 16 12 1,000 2,014E-03 0,02275291 ! focal adhesion formation GO:0048041 35 12 1,000 2,014E-03 0,02264659 ! entry into host cell GO:0030260 32 12 1,000 2,014E-03 0,02254126 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 2,014E-03 0,0224369 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,014E-03 0,02233351 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,014E-03 0,02223106 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,107E-03 0,02314531 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,244E-03 0,02454615 ! response to insulin stimulus GO:0032868 95 46 2,000 2,244E-03 0,02443508 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,244E-03 0,02432501 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,244E-03 0,02421593 ! 'de novo' protein folding GO:0006458 25 13 1,000 2,372E-03 0,02547465 ! organelle fusion GO:0048284 32 13 1,000 2,372E-03 0,02536143 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,372E-03 0,02524921 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 1,000 2,372E-03 0,02513798 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,372E-03 0,02502773 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,372E-03 0,02491844 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 2,372E-03 0,0248101 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,372E-03 0,02470269 ! embryonic placenta development GO:0001892 23 13 1,000 2,372E-03 0,02459622 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,372E-03 0,02449065 ! skeletal muscle tissue development GO:0007519 186 99 3,000 2,432E-03 0,0250048 GO:0060538|skeletal muscle organ development, ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,536E-03 0,02596765 ! activation of caspase activity GO:0006919 84 48 2,000 2,536E-03 0,02585762 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,536E-03 0,02574852 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,536E-03 0,02564033 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 2,691E-03 0,02708644 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,757E-03 0,02763641 ! regulation of S phase GO:0033261 23 14 1,000 2,757E-03 0,02752173 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,757E-03 0,02740801 ! palate development GO:0060021 31 14 1,000 2,757E-03 0,02729522 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,757E-03 0,02718335 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,757E-03 0,0270724 ! arginine metabolic process GO:0006525 17 14 1,000 2,757E-03 0,02696235 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 2,757E-03 0,02685319 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,757E-03 0,02674491 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,757E-03 0,0266375 ! inner ear development GO:0048839 79 50 2,000 2,851E-03 0,02743427 ! negative regulation of immune system process GO:0002683 95 50 2,000 2,851E-03 0,02732497 ! embryonic skeletal system development GO:0048706 85 51 2,000 3,016E-03 0,02879876 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,016E-03 0,02868493 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cell size GO:0045793 27 15 1,000 3,169E-03 0,03001909 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,169E-03 0,02990136 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,169E-03 0,02978456 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,169E-03 0,02966867 ! positive regulation of growth GO:0045927 90 52 2,000 3,188E-03 0,02972859 ! glutamine family amino acid metabolic process GO:0009064 78 54 2,000 3,549E-03 0,03296477 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,608E-03 0,03339189 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,608E-03 0,03326395 ! auditory receptor cell differentiation GO:0042491 32 16 1,000 3,608E-03 0,03313699 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,608E-03 0,03301099 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 3,608E-03 0,03288595 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 1,000 3,608E-03 0,03276185 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,608E-03 0,03263869 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 1,000 3,608E-03 0,03251644 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,608E-03 0,03239511 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,738E-03 0,03343265 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 3,738E-03 0,03330883 ! heart morphogenesis GO:0003007 97 55 2,000 3,738E-03 0,03318592 ! skeletal muscle fiber development GO:0048741 111 56 2,000 3,933E-03 0,03479211 ! nucleotide-excision repair GO:0006289 83 56 2,000 3,933E-03 0,03466467 ! signal complex assembly GO:0007172 41 17 1,000 4,074E-03 0,03577777 ! myoblast differentiation GO:0045445 45 17 1,000 4,074E-03 0,03564767 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,074E-03 0,03551851 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,074E-03 0,03539029 ! nucleobase metabolic process GO:0009112 37 17 1,000 4,074E-03 0,03526299 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 1,000 4,074E-03 0,03513659 ! DNA unwinding during replication GO:0006268 27 17 1,000 4,074E-03 0,03501111 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,074E-03 0,03488651 ! muscle fiber development GO:0048747 112 57 2,000 4,135E-03 0,0352774 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,135E-03 0,03515274 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,135E-03 0,03502896 ! skeletal system morphogenesis GO:0048705 105 59 2,000 4,556E-03 0,0384646 ! establishment of organelle localization GO:0051656 109 59 2,000 4,556E-03 0,03833011 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,567E-03 0,03828487 ! centrosome cycle GO:0007098 25 18 1,000 4,567E-03 0,03815193 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,567E-03 0,03801992 ! glutamine metabolic process GO:0006541 29 18 1,000 4,567E-03 0,03788881 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,567E-03 0,03775861 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,567E-03 0,0376293 ! aromatic compound catabolic process GO:0019439 27 18 1,000 4,567E-03 0,03750087 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 4,776E-03 0,03908873 ! regulation of protein complex assembly GO:0043254 117 61 2,000 5,003E-03 0,04080332 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,003E-03 0,04066547 ! lipid phosphorylation GO:0046834 35 19 1,000 5,085E-03 0,04119558 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,085E-03 0,04105734 ! cellular response to unfolded protein GO:0034620 33 19 1,000 5,085E-03 0,04092002 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 5,085E-03 0,04078362 ! neuromuscular junction development GO:0007528 34 19 1,000 5,085E-03 0,04064813 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,085E-03 0,04051353 ! ear development GO:0043583 103 62 2,000 5,236E-03 0,04157496 ! viral reproductive process GO:0022415 126 62 2,000 5,236E-03 0,0414382 ! gonad development GO:0008406 98 62 2,000 5,236E-03 0,04130234 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 5,475E-03 0,04304871 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 5,629E-03 0,04411845 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,629E-03 0,04397521 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,629E-03 0,04383289 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,629E-03 0,0436915 GO:0010675|regulation of cellular carbohydrate metabolic process, ! DNA duplex unwinding GO:0032508 31 20 1,000 5,629E-03 0,04355101 GO:0032392|DNA geometric change, ! inner ear receptor cell differentiation GO:0060113 37 20 1,000 5,629E-03 0,04341142 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,629E-03 0,04327273 ! germ cell development GO:0007281 118 65 2,000 5,973E-03 0,04576788 ! myeloid cell differentiation GO:0030099 111 65 2,000 5,973E-03 0,04562258 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 6,199E-03 0,04719892 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,199E-03 0,04705002 ! oogenesis GO:0048477 36 21 1,000 6,199E-03 0,04690207 ! collagen fibril organization GO:0030199 59 21 1,000 6,199E-03 0,04675504 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,199E-03 0,04660893 ! actin filament organization GO:0007015 148 66 2,000 6,232E-03 0,0467098 ! negative regulation of cell growth GO:0030308 132 67 2,000 6,497E-03 0,04854805 ! chromosome segregation GO:0007059 113 67 2,000 6,497E-03 0,04839774 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 6,497E-03 0,04824837 ! negative regulation of ligase activity GO:0051352 112 68 2,000 6,769E-03 0,05011412 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 2,000 6,769E-03 0,04996039 ! regulation of lipase activity GO:0060191 130 68 2,000 6,769E-03 0,04980761 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 6,794E-03 0,04983489 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 6,794E-03 0,04968341 ! mechanoreceptor differentiation GO:0042490 40 22 1,000 6,794E-03 0,04953286 ! apoptotic nuclear changes GO:0030262 32 22 1,000 6,794E-03 0,04938321 ! ureteric bud development GO:0001657 43 22 1,000 6,794E-03 0,04923447 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 6,794E-03 0,04908662 GO:0060415|muscle tissue morphogenesis, ! positive regulation of intracellular transport GO:0032388 37 22 1,000 6,794E-03 0,04893965 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 6,794E-03 0,04879356 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 6,794E-03 0,04864834 ! protein stabilization GO:0050821 39 22 1,000 6,794E-03 0,04850399 ! cell cycle checkpoint GO:0000075 137 69 2,000 7,048E-03 0,05017098 ! negative regulation of cell size GO:0045792 134 69 2,000 7,048E-03 0,05002299 ! positive regulation of DNA replication GO:0045740 43 23 1,000 7,413E-03 0,0524606 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,413E-03 0,05230675 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 7,413E-03 0,05215381 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 7,413E-03 0,05200176 ! negative regulation of catabolic process GO:0009895 50 23 1,000 7,413E-03 0,05185059 ! reproductive structure development GO:0048608 113 71 2,000 7,626E-03 0,05318214 ! regulation of caspase activity GO:0043281 122 72 2,000 7,925E-03 0,05510797 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,058E-03 0,05586865 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 8,058E-03 0,05570811 ! regulation of transmembrane transport GO:0034762 38 24 1,000 8,058E-03 0,05554849 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 8,058E-03 0,05538978 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,058E-03 0,05523197 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 8,544E-03 0,05839719 ! organelle localization GO:0051640 136 74 2,000 8,544E-03 0,05823176 ! myelination GO:0042552 45 25 1,000 8,726E-03 0,05930678 ! phototransduction GO:0007602 33 25 1,000 8,726E-03 0,05913971 ! receptor metabolic process GO:0043112 46 25 1,000 8,726E-03 0,05897359 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 8,726E-03 0,0588084 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 8,726E-03 0,05864413 ! cell-matrix adhesion GO:0007160 163 75 2,000 8,863E-03 0,05940085 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 8,863E-03 0,05923584 ! lymphocyte differentiation GO:0030098 167 75 2,000 8,863E-03 0,05907176 ! development of primary sexual characteristics GO:0045137 124 76 2,000 9,19E-03 0,06107921 ! initiation of viral infection GO:0019059 57 26 1,000 9,418E-03 0,06242543 ! molting cycle process GO:0022404 50 26 1,000 9,418E-03 0,06225393 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 9,418E-03 0,06208337 ! microtubule organizing center organization GO:0031023 39 26 1,000 9,418E-03 0,06191374 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 9,418E-03 0,06174504 ! response to estradiol stimulus GO:0032355 40 26 1,000 9,418E-03 0,06157725 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01013434 0,06607919 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01013434 0,0659006 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01013434 0,06572297 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01013434 0,06554629 ! fat cell differentiation GO:0045444 50 27 1,000 0,01013434 0,06537056 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01013434 0,06519578 ! male gonad development GO:0008584 44 27 1,000 0,01013434 0,06502192 ! base-excision repair GO:0006284 41 27 1,000 0,01013434 0,06484899 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01013434 0,06467698 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 0,01021146 0,06499674 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01021146 0,06482524 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,01021146 0,06465465 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 0,01087377 0,06866741 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01087377 0,06848766 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01087377 0,06830884 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01092774 0,0684691 ! regulation of pH GO:0006885 43 29 1,000 0,0116363 0,07271932 ! cell fate determination GO:0001709 60 29 1,000 0,0116363 0,07253093 ! detection of light stimulus GO:0009583 38 29 1,000 0,0116363 0,07234351 ! tissue homeostasis GO:0001894 48 29 1,000 0,0116363 0,07215706 GO:0048871|multicellular organismal homeostasis, ! negative regulation of transport GO:0051051 153 84 2,000 0,01205542 0,07456386 ! negative regulation of growth GO:0045926 155 84 2,000 0,01205542 0,07437267 ! regulation of ligase activity GO:0051340 142 84 2,000 0,01205542 0,07418246 ! cell junction assembly GO:0034329 78 30 1,000 0,01242166 0,07624109 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 0,01242166 0,07604709 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01242166 0,07585408 GO:0008366|axon ensheathment, ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01242166 0,07566204 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01242166 0,07547097 ! mitochondrion organization GO:0007005 148 86 2,000 0,01284297 0,07783425 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01322956 0,07997567 ! inner ear morphogenesis GO:0042472 47 31 1,000 0,01322956 0,07977523 ! mesoderm formation GO:0001707 69 31 1,000 0,01322956 0,07957579 ! regulation of protein transport GO:0051223 154 87 2,000 0,01324754 0,07948524 GO:0070201|regulation of establishment of protein localization, ! spindle organization GO:0007051 46 32 1,000 0,01405973 0,08414852 ! pigment biosynthetic process GO:0046148 66 32 1,000 0,01405973 0,08393971 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,01405973 0,08373194 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01405973 0,08352519 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01405973 0,08331947 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01407834 0,08322477 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,0145046 0,08553449 ! sex differentiation GO:0007548 145 90 2,000 0,0145046 0,08532536 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01491189 0,08750734 ! post-embryonic development GO:0009791 69 33 1,000 0,01491189 0,08729443 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01491189 0,08708255 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01491189 0,08687169 ! cell fate specification GO:0001708 52 33 1,000 0,01491189 0,08666186 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,01578578 0,09151947 ! placenta development GO:0001890 53 34 1,000 0,01578578 0,09129947 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01628242 0,09394605 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01668112 0,09601619 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01668112 0,09578704 ! female gonad development GO:0008585 58 35 1,000 0,01668112 0,09555897 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01668112 0,09533199 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 0,01674513 0,09547103 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01759764 0,10009439 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 0,01759764 0,09985832 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01759764 0,09962336 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01759764 0,0993895 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01759764 0,09915674 ! regulation of protein localization GO:0032880 176 97 2,000 0,01769251 0,09945837 ! interphase GO:0051325 213 98 2,000 0,01817721 0,1019449 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01853509 0,1037103 ! pigment metabolic process GO:0042440 80 37 1,000 0,01853509 0,10346967 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,0194932 0,10856628 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,0194932 0,10831555 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,0194932 0,10806597 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,0194932 0,10781754 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,0194932 0,10757026 ! ear morphogenesis GO:0042471 60 39 1,000 0,0204717 0,11271148 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,0204717 0,11245414 ! segmentation GO:0035282 67 39 1,000 0,0204717 0,11219798 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,0204717 0,11194299 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02147035 0,11713754 ! maintenance of protein location GO:0045185 91 40 1,000 0,02147035 0,11687253 ! cytokinesis GO:0000910 72 40 1,000 0,02147035 0,11660871 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02248888 0,12186541 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02248888 0,12159156 ! female gamete generation GO:0007292 61 41 1,000 0,02248888 0,12131893 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02352704 0,12663549 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02352704 0,12635282 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02458459 0,13173834 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02458459 0,13144558 ! male sex differentiation GO:0046661 76 44 1,000 0,02566126 0,13689799 ! B cell differentiation GO:0030183 107 44 1,000 0,02566126 0,13659512 ! developmental growth GO:0048589 82 44 1,000 0,02566126 0,13629358 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02566126 0,13599337 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02675682 0,14148771 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02675682 0,14117743 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02675682 0,14086851 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02787102 0,14641412 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02787102 0,14609514 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02790827 0,14597237 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02790827 0,14565573 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02790827 0,14534046 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02790827 0,14502655 ! neuron fate determination GO:0048664 7 5 0,000 0,02790827 0,14471399 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02790827 0,14440278 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02790827 0,1440929 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02790827 0,14378435 ! polyol transport GO:0015791 12 5 0,000 0,02790827 0,14347712 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02790827 0,1431712 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02790827 0,14286658 ! response to superoxide GO:0000303 10 5 0,000 0,02790827 0,14256325 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02790827 0,14226121 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02790827 0,14196045 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02790827 0,14166095 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02790827 0,14136272 ! female meiosis GO:0007143 7 5 0,000 0,02790827 0,14106574 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02790827 0,14077 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02790827 0,14047551 ! cobalt ion transport GO:0006824 11 5 0,000 0,02790827 0,14018224 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02790827 0,13989019 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02790827 0,13959936 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02790827 0,13930973 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02790827 0,13902131 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02790827 0,13873407 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02790827 0,13844802 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02790827 0,13816315 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02790827 0,13787945 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02790827 0,13759691 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02790827 0,13731552 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02790827 0,13703529 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02790827 0,13675619 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02790827 0,13647823 ! negative chemotaxis GO:0050919 14 5 0,000 0,02790827 0,1362014 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02790827 0,13592569 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02790827 0,13565109 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02790827 0,1353776 ! behavioral response to pain GO:0048266 9 5 0,000 0,02790827 0,13510521 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02790827 0,13483392 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02790827 0,13456371 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02790827 0,13429458 ! micturition GO:0060073 9 5 0,000 0,02790827 0,13402653 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02790827 0,13375954 ! copulation GO:0007620 9 5 0,000 0,02790827 0,13349362 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02790827 0,13322875 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02790827 0,13296493 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02790827 0,13270216 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02790827 0,13244042 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02790827 0,13217971 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02790827 0,13192002 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02790827 0,13166136 ! grooming behavior GO:0007625 6 5 0,000 0,02790827 0,1314037 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02790827 0,13114705 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02790827 0,13089141 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02790827 0,13063675 ! response to protozoan GO:0001562 10 5 0,000 0,02790827 0,13038309 ! lymph vessel development GO:0001945 10 5 0,000 0,02790827 0,13013041 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02790827 0,12987871 ! endochondral ossification GO:0001958 16 5 0,000 0,02790827 0,12962798 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02790827 0,12937821 ! anagen GO:0042640 6 5 0,000 0,02790827 0,12912941 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02790827 0,12888156 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02790827 0,12863466 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02790827 0,1283887 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02790827 0,12814369 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02790827 0,1278996 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02790827 0,12765645 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02790827 0,12741422 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02790827 0,1271729 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02790827 0,1269325 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02790827 0,126693 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02790827 0,12645441 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02790827 0,12621671 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02790827 0,12597991 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02790827 0,12574399 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02790827 0,12550896 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02790827 0,1252748 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02790827 0,12504151 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02790827 0,12480909 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02790827 0,12457754 ! histidine catabolic process GO:0006548 6 5 0,000 0,02790827 0,12434684 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02790827 0,12411699 ! valine metabolic process GO:0006573 10 5 0,000 0,02790827 0,12388799 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02790827 0,12365984 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02790827 0,12343252 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02790827 0,12320604 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02790827 0,12298039 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02790827 0,12275556 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02790827 0,12253155 ! polyol catabolic process GO:0046174 7 5 0,000 0,02790827 0,12230836 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02790827 0,12208598 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02790827 0,12186441 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02790827 0,12164364 ! muscle cell migration GO:0014812 8 5 0,000 0,02790827 0,12142367 ! mitochondrial fission GO:0000266 8 5 0,000 0,02790827 0,1212045 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02790827 0,12098611 ! mRNA transcription GO:0009299 9 5 0,000 0,02790827 0,12076851 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02790827 0,12055169 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02790827 0,12033565 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02790827 0,12012038 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02790827 0,11990588 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02790827 0,11969214 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02790827 0,11947917 ! response to food GO:0032094 6 5 0,000 0,02790827 0,11926695 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02790827 0,11905548 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02790827 0,11884476 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02790827 0,11863479 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02790827 0,11842556 ! forebrain neuron development GO:0021884 13 5 0,000 0,02790827 0,11821706 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02790827 0,1180093 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02790827 0,11780227 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02790827 0,11759596 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02790827 0,11739037 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02790827 0,1171855 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02790827 0,11698134 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02790827 0,1167779 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02790827 0,11657516 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02790827 0,11637312 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02790827 0,11617178 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02790827 0,11597114 ! basic amino acid transport GO:0015802 11 5 0,000 0,02790827 0,11577119 ! depyrimidination GO:0045008 10 5 0,000 0,02790827 0,11557193 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02790827 0,11537335 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02790827 0,11517546 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02790827 0,11497824 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02790827 0,11478169 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02790827 0,11458582 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02790827 0,11439062 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02790827 0,11419607 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02790827 0,11400219 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02790827 0,11380897 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02790827 0,1136164 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02790827 0,11342448 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02790827 0,11323321 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02790827 0,11304258 ! response to arsenic GO:0046685 10 5 0,000 0,02790827 0,11285259 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02790827 0,11266324 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02790827 0,11247453 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02790827 0,11228644 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02790827 0,11209898 ! response to cadmium ion GO:0046686 7 5 0,000 0,02790827 0,11191215 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02790827 0,11172594 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02790827 0,11154035 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02790827 0,11135538 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02790827 0,11117101 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02790827 0,11098726 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02790827 0,11080411 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02790827 0,11062157 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02790827 0,11043962 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02790827 0,11025828 ! neural tube patterning GO:0021532 7 5 0,000 0,02790827 0,11007753 ! embryonic cleavage GO:0040016 6 5 0,000 0,02790827 0,10989737 ! peroxisome fission GO:0016559 5 5 0,000 0,02790827 0,1097178 ! histone demethylation GO:0016577 10 5 0,000 0,02790827 0,10953881 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02790827 0,10936041 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02790827 0,10918259 ! metaphase plate congression GO:0051310 7 5 0,000 0,02790827 0,10900534 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02790827 0,10882867 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02790827 0,10865258 ! enteric nervous system development GO:0048484 8 5 0,000 0,02790827 0,10847705 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02790827 0,10830208 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02790827 0,10812768 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02790827 0,10795384 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02790827 0,10778056 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02790827 0,10760784 ! plasminogen activation GO:0031639 5 5 0,000 0,02790827 0,10743567 ! B cell homeostasis GO:0001782 13 5 0,000 0,02790827 0,10726404 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02790827 0,10709297 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02790827 0,10692244 ! metaphase GO:0051323 8 5 0,000 0,02790827 0,10675245 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02790827 0,106583 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02790827 0,10641409 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02790827 0,10624571 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02790827 0,10607787 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02790827 0,10591055 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02790827 0,10574377 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02790827 0,1055775 ! response to redox state GO:0051775 5 5 0,000 0,02790827 0,10541176 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02790827 0,10524654 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02790827 0,10508183 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02790827 0,10491764 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02790827 0,10475397 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02790827 0,1045908 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02790827 0,10442814 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02790827 0,10426598 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02790827 0,10410433 ! striatum development GO:0021756 9 5 0,000 0,02790827 0,10394318 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02790827 0,10378252 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02790827 0,10362236 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02790827 0,1034627 ! glial cell migration GO:0008347 11 5 0,000 0,02790827 0,10330353 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02790827 0,10314484 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02790827 0,10298664 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02790827 0,10282893 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02790827 0,1026717 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02790827 0,10251495 ! neuroprotection GO:0043526 6 5 0,000 0,02790827 0,10235868 ! neural plate development GO:0001840 8 5 0,000 0,02790827 0,10220288 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02790827 0,10204756 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02790827 0,1018927 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02790827 0,10173832 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02790827 0,1015844 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02790827 0,10143095 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02790827 0,10127797 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02790827 0,10112544 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02790827 0,10097337 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02790827 0,10082176 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02790827 0,1006706 ! spindle assembly GO:0051225 6 5 0,000 0,02790827 0,1005199 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02790827 0,10036964 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02790827 0,10021984 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02790827 0,10007048 ! drug metabolic process GO:0017144 6 5 0,000 0,02790827 0,09992156 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02790827 0,09977309 ! organ regeneration GO:0031100 7 5 0,000 0,02790827 0,09962506 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02790827 0,09947747 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02790827 0,09933031 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02790827 0,09918359 ! endosome transport GO:0016197 108 47 1,000 0,02900361 0,10292433 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02900361 0,10277274 ! protein homooligomerization GO:0051260 76 47 1,000 0,02900361 0,10262161 ! mitochondrial transport GO:0006839 82 48 1,000 0,03015436 0,10653657 ! cellular component disassembly GO:0022411 86 48 1,000 0,03015436 0,10638035 ! regulation of action potential GO:0001508 95 49 1,000 0,03132303 0,11034146 ! endocrine system development GO:0035270 104 49 1,000 0,03132303 0,11018015 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03132303 0,1100193 ! histone modification GO:0016570 91 50 1,000 0,03250939 0,1140198 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0333963 0,11695996 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0333963 0,11678996 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0333963 0,11662046 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0333963 0,11645144 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0333963 0,11628292 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0333963 0,11611488 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0333963 0,11594732 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0333963 0,11578025 ! sleep GO:0030431 13 6 0,000 0,0333963 0,11561366 ! response to oxygen radical GO:0000305 11 6 0,000 0,0333963 0,11544755 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0333963 0,11528191 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0333963 0,11511675 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0333963 0,11495207 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0333963 0,11478785 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0333963 0,1146241 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0333963 0,11446082 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0333963 0,114298 ! forebrain regionalization GO:0021871 8 6 0,000 0,0333963 0,11413565 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0333963 0,11397375 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0333963 0,11381232 ! response to zinc ion GO:0010043 9 6 0,000 0,0333963 0,11365134 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0333963 0,11349081 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0333963 0,11333074 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0333963 0,11317112 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0333963 0,11301195 ! malate metabolic process GO:0006108 11 6 0,000 0,0333963 0,11285322 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0333963 0,11269494 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0333963 0,11253711 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0333963 0,11237971 ! opsonization GO:0008228 8 6 0,000 0,0333963 0,11222276 ! mating behavior GO:0007617 7 6 0,000 0,0333963 0,11206624 ! neuron remodeling GO:0016322 15 6 0,000 0,0333963 0,11191016 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0333963 0,11175451 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0333963 0,1115993 ! equilibrioception GO:0050957 14 6 0,000 0,0333963 0,11144451 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0333963 0,11129016 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0333963 0,11113623 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0333963 0,11098273 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0333963 0,11082965 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0333963 0,11067699 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0333963 0,11052475 ! toxin metabolic process GO:0009404 11 6 0,000 0,0333963 0,11037293 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0333963 0,11022153 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0333963 0,11007054 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0333963 0,10991997 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0333963 0,1097698 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0333963 0,10962005 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0333963 0,1094707 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0333963 0,10932176 ! thymic T cell selection GO:0045061 12 6 0,000 0,0333963 0,10917323 ! protein lipoylation GO:0009249 10 6 0,000 0,0333963 0,10902509 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0333963 0,10887736 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0333963 0,10873003 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0333963 0,1085831 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0333963 0,10843656 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0333963 0,10829042 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,0333963 0,10814468 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0333963 0,10799932 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0333963 0,10785436 ! hyperosmotic response GO:0006972 9 6 0,000 0,0333963 0,10770978 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0333963 0,10756559 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0333963 0,10742178 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0333963 0,10727836 ! response to ATP GO:0033198 7 6 0,000 0,0333963 0,10713533 ! neutrophil activation GO:0042119 8 6 0,000 0,0333963 0,10699267 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0333963 0,10685039 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0333963 0,10670849 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0333963 0,10656697 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0333963 0,10642582 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0333963 0,10628505 ! neuron apoptosis GO:0051402 9 6 0,000 0,0333963 0,10614464 ! nucleoside salvage GO:0043174 9 6 0,000 0,0333963 0,10600461 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0333963 0,10586495 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0333963 0,10572565 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0333963 0,10558672 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0333963 0,10544816 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0333963 0,10530995 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0333963 0,10517211 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0333963 0,10503463 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0333963 0,10489751 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0333963 0,10476075 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0333963 0,10462434 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0333963 0,10448829 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0333963 0,10435259 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0333963 0,10421724 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0333963 0,10408225 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0333963 0,1039476 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0333963 0,1038133 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0333963 0,10367935 ! neural nucleus development GO:0048857 14 6 0,000 0,0333963 0,10354574 ! astrocyte development GO:0014002 15 6 0,000 0,0333963 0,10341248 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0333963 0,10327956 ! interaction with symbiont GO:0051702 13 6 0,000 0,0333963 0,10314698 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0333963 0,10301474 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0333963 0,10288284 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0333963 0,10275127 ! response to copper ion GO:0046688 10 6 0,000 0,0333963 0,10262004 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0333963 0,10248915 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0333963 0,10235859 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0333963 0,10222836 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0333963 0,10209847 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0333963 0,1019689 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0333963 0,10183966 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0333963 0,10171075 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0333963 0,10158217 ! hair follicle maturation GO:0048820 7 6 0,000 0,0333963 0,10145391 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0333963 0,10132597 ! Schwann cell development GO:0014044 15 6 0,000 0,0333963 0,10119836 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0333963 0,10107106 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0333963 0,10094409 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0333963 0,10081743 ! subpallium development GO:0021544 10 6 0,000 0,0333963 0,1006911 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0333963 0,10056507 ! histone ubiquitination GO:0016574 8 6 0,000 0,0333963 0,10043937 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0333963 0,10031398 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0333963 0,1001889 ! G2 phase GO:0051319 16 6 0,000 0,0333963 0,10006413 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0333963 0,09993967 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0333963 0,09981552 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0333963 0,09969168 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0333963 0,09956815 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0333963 0,09944492 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0333963 0,099322 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0333963 0,09919938 ! receptor internalization GO:0031623 10 6 0,000 0,0333963 0,09907706 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0333963 0,09895504 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0333963 0,09883333 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0333963 0,09871191 ! protein deubiquitination GO:0016579 14 6 0,000 0,0333963 0,09859079 ! protein destabilization GO:0031648 9 6 0,000 0,0333963 0,09846997 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0333963 0,09834944 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0333963 0,09822921 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0333963 0,09810927 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0333963 0,09798963 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0333963 0,09787027 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0333963 0,09775121 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0333963 0,09763244 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0333963 0,09751395 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0333963 0,09739575 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0333963 0,09727784 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0333963 0,09716021 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0333963 0,09704287 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0333963 0,09692581 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0333963 0,09680903 ! catecholamine transport GO:0051937 9 6 0,000 0,0333963 0,09669253 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0333963 0,09657632 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0333963 0,09646038 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0333963 0,09634472 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0333963 0,09622933 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0333963 0,09611423 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0333963 0,0959994 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0333963 0,09588484 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0333963 0,09577055 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0333963 0,09565654 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0333963 0,0955428 ! positive regulation of binding GO:0051099 78 51 1,000 0,03371318 0,09633482 ! viral infectious cycle GO:0019058 99 51 1,000 0,03371318 0,09622054 ! cellular amino acid biosynthetic process GO:0008652 75 51 1,000 0,03371318 0,09610654 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,03371318 0,0959928 ! vesicle organization GO:0016050 107 51 1,000 0,03371318 0,09587934 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03371318 0,09576614 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,0349342 0,09911754 ! membrane fusion GO:0006944 110 52 1,000 0,0349342 0,0990008 ! covalent chromatin modification GO:0016569 101 52 1,000 0,0349342 0,09888433 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,0349342 0,09876813 ! synapse organization GO:0050808 85 52 1,000 0,0349342 0,0986522 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03617219 0,10202849 ! cell maturation GO:0048469 100 53 1,000 0,03617219 0,10190902 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03617219 0,10178982 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03742695 0,10519771 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03742695 0,10507496 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03869823 0,10851742 ! gastrulation GO:0007369 112 55 1,000 0,03869823 0,10839109 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03869823 0,10826506 ! tRNA transcription GO:0009304 14 7 0,000 0,03885353 0,10857327 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03885353 0,10844732 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03885353 0,10832165 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03885353 0,10819628 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03885353 0,1080712 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03885353 0,10794641 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03885353 0,1078219 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03885353 0,10769768 ! prostate gland development GO:0030850 13 7 0,000 0,03885353 0,10757375 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03885353 0,1074501 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03885353 0,10732674 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03885353 0,10720366 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03885353 0,10708086 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03885353 0,10695834 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03885353 0,1068361 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03885353 0,10671414 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03885353 0,10659246 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03885353 0,10647106 ! glycolipid transport GO:0046836 10 7 0,000 0,03885353 0,10634993 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03885353 0,10622908 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03885353 0,1061085 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03885353 0,1059882 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03885353 0,10586816 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03885353 0,1057484 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03885353 0,10562891 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03885353 0,10550969 ! mRNA stabilization GO:0048255 18 7 0,000 0,03885353 0,10539074 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03885353 0,10527206 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03885353 0,10515364 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03885353 0,10503549 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03885353 0,10491761 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03885353 0,10479999 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03885353 0,10468263 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03885353 0,10456553 ! lipoprotein transport GO:0042953 14 7 0,000 0,03885353 0,1044487 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03885353 0,10433213 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03885353 0,10421582 ! rhythmic behavior GO:0007622 15 7 0,000 0,03885353 0,10409976 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03885353 0,10398397 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03885353 0,10386843 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03885353 0,10375315 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03885353 0,10363812 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03885353 0,10352335 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03885353 0,10340884 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03885353 0,10329457 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03885353 0,10318056 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03885353 0,1030668 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03885353 0,10295329 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03885353 0,10284003 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03885353 0,10272702 ! spinal cord patterning GO:0021511 13 7 0,000 0,03885353 0,10261426 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03885353 0,10250174 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03885353 0,10238947 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03885353 0,10227745 ! adrenal gland development GO:0030325 17 7 0,000 0,03885353 0,10216567 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03885353 0,10205414 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03885353 0,10194284 ! ovulation GO:0030728 9 7 0,000 0,03885353 0,1018318 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03885353 0,10172099 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03885353 0,10161042 ! microtubule nucleation GO:0007020 20 7 0,000 0,03885353 0,1015001 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03885353 0,10139001 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03885353 0,10128016 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03885353 0,10117055 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03885353 0,10106118 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03885353 0,10095204 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03885353 0,10084314 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03885353 0,10073447 ! galactose metabolic process GO:0006012 13 7 0,000 0,03885353 0,10062604 ! response to dietary excess GO:0002021 8 7 0,000 0,03885353 0,10051784 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03885353 0,10040987 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03885353 0,10030213 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03885353 0,10019463 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03885353 0,10008735 ! organ growth GO:0035265 15 7 0,000 0,03885353 0,09998031 ! purine salvage GO:0043101 10 7 0,000 0,03885353 0,09987349 ! nucleoside transport GO:0015858 8 7 0,000 0,03885353 0,0997669 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03885353 0,09966054 ! parturition GO:0007567 14 7 0,000 0,03885353 0,09955441 ! rRNA modification GO:0000154 14 7 0,000 0,03885353 0,0994485 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03885353 0,09934281 ! spindle checkpoint GO:0031577 15 7 0,000 0,03885353 0,09923735 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03885353 0,09913212 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03885353 0,09902711 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03885353 0,09892232 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03885353 0,09881775 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03885353 0,0987134 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03885353 0,09860927 ! fibrinolysis GO:0042730 10 7 0,000 0,03885353 0,09850536 ! eating behavior GO:0042755 7 7 0,000 0,03885353 0,09840167 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03885353 0,0982982 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03885353 0,09819495 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03885353 0,09809191 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03885353 0,09798909 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03885353 0,09788648 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03885353 0,09778409 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03885353 0,09768191 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03885353 0,09757995 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03885353 0,09747819 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03885353 0,09737665 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03885353 0,09727533 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03885353 0,09717421 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03885353 0,0970733 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03885353 0,0969726 ! regulation of meiosis GO:0040020 12 7 0,000 0,03885353 0,09687211 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03885353 0,09677183 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03885353 0,09667176 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03885353 0,09657189 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03885353 0,09647223 ! transcription termination GO:0006353 13 7 0,000 0,03885353 0,09637277 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03885353 0,09627352 ! anaphase GO:0051322 17 7 0,000 0,03885353 0,09617447 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03885353 0,09607563 ! axonal fasciculation GO:0007413 18 7 0,000 0,03885353 0,09597699 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03885353 0,09587855 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03885353 0,09578032 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03885353 0,09568228 ! diuresis GO:0030146 12 7 0,000 0,03885353 0,09558445 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03885353 0,09548681 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03885353 0,09538938 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03885353 0,09529214 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03885353 0,0951951 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03885353 0,09509826 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03885353 0,09500161 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03885353 0,09490517 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03885353 0,09480891 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03885353 0,09471286 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03885353 0,09461699 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03885353 0,09452132 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03885353 0,09442585 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03885353 0,09433056 ! lymph node development GO:0048535 10 7 0,000 0,03885353 0,09423547 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03885353 0,09414057 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03885353 0,09404586 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03885353 0,09395134 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03885353 0,09385702 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03885353 0,09376288 ! adult feeding behavior GO:0008343 9 7 0,000 0,03885353 0,09366893 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03885353 0,09357516 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03885353 0,09348159 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03885353 0,0933882 ! muscle adaptation GO:0043500 14 7 0,000 0,03885353 0,093295 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03885353 0,09320198 ! retina homeostasis GO:0001895 12 7 0,000 0,03885353 0,09310915 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03885353 0,09301651 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03885353 0,09292404 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03885353 0,09283177 ! protein prenylation GO:0018342 18 7 0,000 0,03885353 0,09273967 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03885353 0,09264776 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03885353 0,09255603 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03885353 0,09246448 ! maintenance of location GO:0051235 118 57 1,000 0,0412895 0,09816456 ! lipid modification GO:0030258 97 57 1,000 0,0412895 0,09806766 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,0412895 0,09797094 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04260904 0,10100231 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04394422 0,10406477 ! DNA catabolic process GO:0006308 86 59 1,000 0,04394422 0,10396244 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04394422 0,10386032 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04428013 0,10455151 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04428013 0,10444901 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04428013 0,1043467 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04428013 0,1042446 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04428013 0,1041427 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04428013 0,104041 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04428013 0,1039395 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04428013 0,10383819 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04428013 0,10373708 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04428013 0,10363617 ! meiotic prophase I GO:0007128 13 8 0,000 0,04428013 0,10353546 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04428013 0,10343494 ! oligopeptide transport GO:0006857 15 8 0,000 0,04428013 0,10333461 ! UTP metabolic process GO:0046051 8 8 0,000 0,04428013 0,10323448 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04428013 0,10313455 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04428013 0,1030348 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04428013 0,10293525 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04428013 0,10283589 ! succinate metabolic process GO:0006105 14 8 0,000 0,04428013 0,10273673 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04428013 0,10263775 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04428013 0,10253897 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04428013 0,10244037 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04428013 0,10234197 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04428013 0,10224375 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04428013 0,10214572 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04428013 0,10204788 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04428013 0,10195023 ! reflex GO:0060004 16 8 0,000 0,04428013 0,10185276 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04428013 0,10175548 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04428013 0,10165838 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04428013 0,10156147 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04428013 0,10146475 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04428013 0,10136821 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04428013 0,10127185 ! pigment granule organization GO:0048753 16 8 0,000 0,04428013 0,10117567 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04428013 0,10107968 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04428013 0,10098387 ! histidine metabolic process GO:0006547 16 8 0,000 0,04428013 0,10088824 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04428013 0,1007928 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04428013 0,10069753 ! glycine catabolic process GO:0006546 13 8 0,000 0,04428013 0,10060244 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04428013 0,10050753 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04428013 0,1004128 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04428013 0,10031825 ! melanin metabolic process GO:0006582 15 8 0,000 0,04428013 0,10022388 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04428013 0,10012969 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04428013 0,10003567 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04428013 0,09994183 ! macrophage activation GO:0042116 12 8 0,000 0,04428013 0,09984816 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04428013 0,09975467 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04428013 0,09966135 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04428013 0,09956821 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04428013 0,09947524 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04428013 0,09938245 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04428013 0,09928983 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04428013 0,09919738 ! osteoblast development GO:0002076 16 8 0,000 0,04428013 0,0991051 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04428013 0,099013 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04428013 0,09892106 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04428013 0,0988293 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04428013 0,09873771 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04428013 0,09864628 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04428013 0,09855503 ! response to UV-B GO:0010224 16 8 0,000 0,04428013 0,09846394 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04428013 0,09837302 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04428013 0,09828227 ! intermediate filament organization GO:0045109 12 8 0,000 0,04428013 0,09819169 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04428013 0,09810128 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04428013 0,09801103 ! cellular extravasation GO:0045123 12 8 0,000 0,04428013 0,09792094 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04428013 0,09783102 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04428013 0,09774127 ! response to antibiotic GO:0046677 11 8 0,000 0,04428013 0,09765168 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04428013 0,09756226 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04428013 0,097473 ! DNA topological change GO:0006265 12 8 0,000 0,04428013 0,0973839 ! response to tropane GO:0014073 15 8 0,000 0,04428013 0,09729496 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04428013 0,09720619 ! melanosome transport GO:0032402 13 8 0,000 0,04428013 0,09711758 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04428013 0,09702913 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04428013 0,09694084 ! mast cell activation GO:0045576 14 8 0,000 0,04428013 0,09685271 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04428013 0,09676475 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04428013 0,09667694 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04428013 0,09658929 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04428013 0,0965018 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04428013 0,09641447 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04428013 0,09632729 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04428013 0,09624028 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04428013 0,09615342 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04428013 0,09606671 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04428013 0,09598017 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04428013 0,09589378 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04428013 0,09580754 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04428013 0,09572146 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04428013 0,09563553 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04428013 0,09554976 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04428013 0,09546414 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04428013 0,09537868 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04428013 0,09529337 ! hormone catabolic process GO:0042447 17 8 0,000 0,04428013 0,09520821 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04428013 0,0951232 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04428013 0,09503835 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04428013 0,09495364 ! ATP catabolic process GO:0006200 11 8 0,000 0,04428013 0,09486909 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04428013 0,09478468 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04428013 0,09470043 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04428013 0,09461633 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04428013 0,09453237 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04428013 0,09444857 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04428013 0,09436491 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04428013 0,0942814 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04428013 0,09419804 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04428013 0,09411483 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04428013 0,09403176 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04428013 0,09394884 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04428013 0,09386607 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04428013 0,09378344 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04428013 0,09370095 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04428013 0,09361862 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04428013 0,09353642 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,04529484 0,09559595 ! camera-type eye development GO:0043010 116 60 1,000 0,04529484 0,09551216 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,04529484 0,09542853 ! mesoderm development GO:0007498 119 61 1,000 0,04666067 0,09822009 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,04943712 0,10397352 ! detection of external stimulus GO:0009581 91 63 1,000 0,04943712 0,10388271 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,04943712 0,10379206 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,04943712 0,10370157 ! axon extension GO:0048675 15 9 0,000 0,04967627 0,10411246 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04967627 0,10402184 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04967627 0,10393139 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04967627 0,10384109 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04967627 0,10375095 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04967627 0,10366097 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04967627 0,10357114 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04967627 0,10348147 ! phosphate transport GO:0006817 19 9 0,000 0,04967627 0,10339195 ! reproductive behavior GO:0019098 19 9 0,000 0,04967627 0,10330259 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04967627 0,10321338 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04967627 0,10312433 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04967627 0,10303543 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04967627 0,10294668 ! GTP metabolic process GO:0046039 9 9 0,000 0,04967627 0,10285809 ! RNA methylation GO:0001510 15 9 0,000 0,04967627 0,10276965 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04967627 0,10268136 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,04967627 0,10259322 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04967627 0,10250523 ! regulation of histone modification GO:0031056 12 9 0,000 0,04967627 0,10241739 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04967627 0,10232971 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04967627 0,10224217 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04967627 0,10215478 ! chemosensory behavior GO:0007635 20 9 0,000 0,04967627 0,10206755 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04967627 0,10198046 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04967627 0,10189352 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04967627 0,10180673 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04967627 0,10172008 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04967627 0,10163359 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04967627 0,10154724 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04967627 0,10146103 ! protein targeting to ER GO:0045047 22 9 0,000 0,04967627 0,10137498 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04967627 0,10128907 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04967627 0,1012033 ! T cell selection GO:0045058 23 9 0,000 0,04967627 0,10111768 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04967627 0,1010322 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04967627 0,10094687 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04967627 0,10086169 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04967627 0,10077664 ! mannose metabolic process GO:0006013 13 9 0,000 0,04967627 0,10069174 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04967627 0,10060699 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04967627 0,10052237 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04967627 0,1004379 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04967627 0,10035357 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04967627 0,10026938 ! ruffle organization GO:0031529 15 9 0,000 0,04967627 0,10018533 ! retinol metabolic process GO:0042572 18 9 0,000 0,04967627 0,10010142 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04967627 0,10001766 ! behavioral fear response GO:0001662 22 9 0,000 0,04967627 0,09993403 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04967627 0,09985054 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04967627 0,09976719 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04967627 0,09968399 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04967627 0,09960092 ! segment specification GO:0007379 13 9 0,000 0,04967627 0,09951798 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04967627 0,09943519 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04967627 0,09935253 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04967627 0,09927002 ! response to amine stimulus GO:0014075 13 9 0,000 0,04967627 0,09918763 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04967627 0,09910539 ! erythrocyte development GO:0048821 15 9 0,000 0,04967627 0,09902328 ! gas homeostasis GO:0033483 16 9 0,000 0,04967627 0,09894131 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04967627 0,09885947 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04967627 0,09877777 ! renal water homeostasis GO:0003091 14 9 0,000 0,04967627 0,0986962 ! postreplication repair GO:0006301 22 9 0,000 0,04967627 0,09861477 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04967627 0,09853347 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04967627 0,09845231 ! icosanoid secretion GO:0032309 15 9 0,000 0,04967627 0,09837127 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04967627 0,09829038 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04967627 0,09820961 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04967627 0,09812898 ! regulation of cell division GO:0051302 15 9 0,000 0,04967627 0,09804848 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04967627 0,09796811 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04967627 0,09788788 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04967627 0,09780777 ! sterol catabolic process GO:0016127 11 9 0,000 0,04967627 0,0977278 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04967627 0,09764796 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04967627 0,09756824 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04967627 0,09748866 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04967627 0,09740921 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04967627 0,09732988 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04967627 0,09725069 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04967627 0,09717162 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04967627 0,09709269 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04967627 0,09701388 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04967627 0,0969352 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04967627 0,09685664 ! pigment granule transport GO:0051904 17 9 0,000 0,04967627 0,09677822 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04967627 0,09669992 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04967627 0,09662174 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04967627 0,0965437 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04967627 0,09646578 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04967627 0,09638798 ! mitochondrion localization GO:0051646 15 9 0,000 0,04967627 0,09631031 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,05084732 0,09850134 GO:0048609|reproductive process in a multicellular organism, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05371066 0,10396447 ! extracellular matrix organization GO:0030198 133 66 1,000 0,05371066 0,1038809 ! developmental maturation GO:0021700 116 66 1,000 0,05371066 0,10379746 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05504212 0,10628518 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05504212 0,10619995 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05504212 0,10611485 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,05504212 0,10602989 ! synapsis GO:0007129 13 10 0,000 0,05504212 0,10594507 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05504212 0,10586038 ! N-glycan processing GO:0006491 20 10 0,000 0,05504212 0,10577583 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05504212 0,10569141 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05504212 0,10560713 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05504212 0,10552298 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05504212 0,10543896 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05504212 0,10535508 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05504212 0,10527133 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05504212 0,10518772 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05504212 0,10510423 ! androgen metabolic process GO:0008209 17 10 0,000 0,05504212 0,10502088 ! phospholipid efflux GO:0033700 16 10 0,000 0,05504212 0,10493767 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05504212 0,10485458 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05504212 0,10477163 ! lung alveolus development GO:0048286 26 10 0,000 0,05504212 0,1046888 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05504212 0,10460611 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05504212 0,10452355 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05504212 0,10444112 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05504212 0,10435881 ! endoderm development GO:0007492 16 10 0,000 0,05504212 0,10427664 ! arginine catabolic process GO:0006527 13 10 0,000 0,05504212 0,1041946 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05504212 0,10411268 ! proline metabolic process GO:0006560 13 10 0,000 0,05504212 0,1040309 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05504212 0,10394924 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05504212 0,10386771 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05504212 0,10378631 ! V(D)J recombination GO:0033151 28 10 0,000 0,05504212 0,10370504 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05504212 0,10362389 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05504212 0,10354287 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05504212 0,10346198 ! B cell proliferation GO:0042100 18 10 0,000 0,05504212 0,10338121 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05504212 0,10330057 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05504212 0,10322006 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05504212 0,10313967 ! epithelial cell development GO:0002064 20 10 0,000 0,05504212 0,1030594 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05504212 0,10297927 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05504212 0,10289925 ! macroautophagy GO:0016236 17 10 0,000 0,05504212 0,10281936 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05504212 0,10273959 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05504212 0,10265995 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05504212 0,10258043 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05504212 0,10250103 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05504212 0,10242176 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05504212 0,10234261 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05504212 0,10226358 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05504212 0,10218467 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05504212 0,10210589 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05504212 0,10202722 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05504212 0,10194868 ! response to dsRNA GO:0043331 20 10 0,000 0,05504212 0,10187026 ! DNA ligation GO:0006266 19 10 0,000 0,05504212 0,10179196 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05504212 0,10171378 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05504212 0,10163571 ! melanosome localization GO:0032400 16 10 0,000 0,05504212 0,10155777 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05504212 0,10147995 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05504212 0,10140225 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05504212 0,10132466 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05504212 0,1012472 ! mRNA cleavage GO:0006379 17 10 0,000 0,05504212 0,10116985 ! protein sumoylation GO:0016925 15 10 0,000 0,05504212 0,10109262 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05504212 0,10101551 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05504212 0,10093852 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05504212 0,10086164 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05504212 0,10078488 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05504212 0,10070824 ! salivary gland development GO:0007431 27 10 0,000 0,05504212 0,10063171 ! prophase GO:0051324 15 10 0,000 0,05504212 0,1005553 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05504212 0,10047901 ! apical protein localization GO:0045176 15 10 0,000 0,05504212 0,10040283 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05504212 0,10032677 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05504212 0,10025082 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05504212 0,10017499 ! midbrain development GO:0030901 13 10 0,000 0,05504212 0,10009927 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05504212 0,10002367 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05504212 0,09994818 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05504212 0,0998728 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05504212 0,09979754 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05504212 0,09972239 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05504212 0,09964736 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05504212 0,09957243 ! detection of calcium ion GO:0005513 23 10 0,000 0,05504212 0,09949762 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05504212 0,09942292 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05504212 0,09934834 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05504212 0,09927386 ! activation of innate immune response GO:0002218 12 10 0,000 0,05504212 0,0991995 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05504212 0,09912525 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05504212 0,09905111 ! response to nicotine GO:0035094 20 10 0,000 0,05504212 0,09897708 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05504212 0,09890316 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05504212 0,09882935 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05504212 0,09875566 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,05516337 0,09889946 ! activation of MAPK activity GO:0000187 115 67 1,000 0,05516337 0,09882582 ! lung development GO:0030324 144 67 1,000 0,05516337 0,09875229 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,05516337 0,09867887 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,05662986 0,10122693 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,05662986 0,10115178 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,05662986 0,10107674 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,05810991 0,10364155 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,05810991 0,10356478 ! respiratory tube development GO:0030323 150 70 1,000 0,05960333 0,10614775 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06037785 0,10744756 ! respiratory burst GO:0045730 17 11 0,000 0,06037785 0,10736815 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06037785 0,10728885 ! neuron fate specification GO:0048665 17 11 0,000 0,06037785 0,10720967 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06037785 0,10713061 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06037785 0,10705166 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06037785 0,10697283 ! thyroid gland development GO:0030878 26 11 0,000 0,06037785 0,10689412 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06037785 0,10681552 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06037785 0,10673703 ! response to pain GO:0048265 24 11 0,000 0,06037785 0,10665867 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06037785 0,10658041 ! T cell proliferation GO:0042098 26 11 0,000 0,06037785 0,10650227 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06037785 0,10642425 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06037785 0,10634634 ! bone resorption GO:0045453 16 11 0,000 0,06037785 0,10626855 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06037785 0,10619086 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06037785 0,1061133 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06037785 0,10603584 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06037785 0,1059585 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06037785 0,10588127 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06037785 0,10580415 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06037785 0,10572715 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06037785 0,10565026 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06037785 0,10557348 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,06037785 0,10549681 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06037785 0,10542025 ! UV protection GO:0009650 19 11 0,000 0,06037785 0,1053438 ! adult heart development GO:0007512 14 11 0,000 0,06037785 0,10526747 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06037785 0,10519124 ! temperature homeostasis GO:0001659 17 11 0,000 0,06037785 0,10511513 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06037785 0,10503912 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06037785 0,10496322 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06037785 0,10488744 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06037785 0,10481176 ! regulation of organ growth GO:0046620 13 11 0,000 0,06037785 0,1047362 ! pigment granule localization GO:0051875 20 11 0,000 0,06037785 0,10466074 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06037785 0,10458539 ! vasoconstriction GO:0042310 18 11 0,000 0,06037785 0,10451015 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06037785 0,10443501 ! embryonic axis specification GO:0000578 18 11 0,000 0,06037785 0,10435999 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06037785 0,10428507 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06037785 0,10421026 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06037785 0,10413556 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06037785 0,10406096 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06037785 0,10398647 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06037785 0,10391209 ! zymogen activation GO:0031638 15 11 0,000 0,06037785 0,10383781 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06037785 0,10376365 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06037785 0,10368958 ! nucleosome positioning GO:0016584 15 11 0,000 0,06037785 0,10361562 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06037785 0,10354177 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06037785 0,10346802 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06037785 0,10339438 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06037785 0,10332084 ! acid secretion GO:0046717 18 11 0,000 0,06037785 0,10324741 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06037785 0,10317408 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06037785 0,10310085 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06037785 0,10302773 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06037785 0,10295472 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06037785 0,1028818 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06037785 0,10280899 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06037785 0,10273628 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06037785 0,10266368 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06037785 0,10259117 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,06037785 0,10251877 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06037785 0,10244648 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06037785 0,10237428 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06037785 0,10230219 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06037785 0,10223019 ! defense response to fungus GO:0050832 13 11 0,000 0,06037785 0,1021583 ! developmental induction GO:0031128 19 11 0,000 0,06037785 0,10208651 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06037785 0,10201482 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06037785 0,10194323 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06037785 0,10187174 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06037785 0,10180035 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06037785 0,10172906 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06037785 0,10165787 ! amine catabolic process GO:0009310 117 71 1,000 0,06110992 0,10281852 ! B cell activation GO:0042113 160 71 1,000 0,06110992 0,10274667 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,0626295 0,10522805 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,0626295 0,10515462 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,0626295 0,10508129 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,0626295 0,10500806 ! respiratory system development GO:0060541 153 72 1,000 0,0626295 0,10493494 ! learning or memory GO:0007611 147 73 1,000 0,06416185 0,10742757 ! axon guidance GO:0007411 139 73 1,000 0,06416185 0,10735287 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06568363 0,10982266 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06568363 0,10974639 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06568363 0,10967023 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06568363 0,10959418 ! cartilage condensation GO:0001502 20 12 0,000 0,06568363 0,10951823 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06568363 0,10944239 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06568363 0,10936665 ! protein complex disassembly GO:0043241 27 12 0,000 0,06568363 0,10929101 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,06568363 0,10921548 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06568363 0,10914006 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06568363 0,10906474 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06568363 0,10898952 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06568363 0,10891441 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06568363 0,1088394 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06568363 0,10876449 ! drug transport GO:0015893 16 12 0,000 0,06568363 0,10868969 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06568363 0,10861499 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06568363 0,10854039 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06568363 0,10846589 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06568363 0,1083915 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06568363 0,10831721 ! forebrain cell migration GO:0021885 21 12 0,000 0,06568363 0,10824302 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06568363 0,10816893 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06568363 0,10809494 ! fear response GO:0042596 26 12 0,000 0,06568363 0,10802106 ! monoamine transport GO:0015844 18 12 0,000 0,06568363 0,10794727 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06568363 0,10787359 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06568363 0,1078 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06568363 0,10772652 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06568363 0,10765314 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06568363 0,10757985 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06568363 0,10750667 ! protein homotetramerization GO:0051289 21 12 0,000 0,06568363 0,10743359 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06568363 0,1073606 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06568363 0,10728772 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06568363 0,10721493 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06568363 0,10714224 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06568363 0,10706965 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06568363 0,10699716 ! cranial nerve development GO:0021545 20 12 0,000 0,06568363 0,10692477 ! fucose catabolic process GO:0019317 22 12 0,000 0,06568363 0,10685247 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06568363 0,10678027 ! histone methylation GO:0016571 26 12 0,000 0,06568363 0,10670817 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06568363 0,10663617 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06568363 0,10656427 ! gland morphogenesis GO:0022612 29 12 0,000 0,06568363 0,10649246 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06568363 0,10642074 ! T cell homeostasis GO:0043029 25 12 0,000 0,06568363 0,10634913 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06568363 0,10627761 ! spleen development GO:0048536 22 12 0,000 0,06568363 0,10620619 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06568363 0,10613486 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06568363 0,10606363 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06568363 0,10599249 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06568363 0,10592145 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06568363 0,10585051 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06568363 0,10577966 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06568363 0,1057089 ! response to cold GO:0009409 17 12 0,000 0,06568363 0,10563824 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06568363 0,10556767 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06568363 0,1054972 ! neurotransmitter transport GO:0006836 123 74 1,000 0,06570681 0,10546403 ! exocytosis GO:0006887 133 74 1,000 0,06570681 0,10539372 ! eye development GO:0001654 143 74 1,000 0,06570681 0,1053235 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07041535 0,11279583 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07095962 0,11359205 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 18 13 0,000 0,07095962 0,11351652 ! peroxisomal transport GO:0043574 24 13 0,000 0,07095962 0,11344109 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07095962 0,11336577 ! lipid localization GO:0010876 28 13 0,000 0,07095962 0,11329054 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07095962 0,11321542 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07095962 0,11314039 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07095962 0,11306546 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07095962 0,11299063 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07095962 0,1129159 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07095962 0,11284127 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07095962 0,11276674 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07095962 0,11269231 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07095962 0,11261797 ! methionine metabolic process GO:0006555 27 13 0,000 0,07095962 0,11254374 ! plasma membrane organization GO:0007009 24 13 0,000 0,07095962 0,1124696 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07095962 0,11239555 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07095962 0,11232161 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07095962 0,11224776 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07095962 0,11217401 ! exocrine system development GO:0035272 32 13 0,000 0,07095962 0,11210036 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07095962 0,1120268 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07095962 0,11195334 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07095962 0,11187998 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07095962 0,11180671 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07095962 0,11173354 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07095962 0,11166046 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07095962 0,11158748 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07095962 0,1115146 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07095962 0,11144181 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07095962 0,11136911 ! ribosome assembly GO:0042255 17 13 0,000 0,07095962 0,11129651 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07095962 0,111224 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07095962 0,11115159 ! chromatin silencing GO:0006342 26 13 0,000 0,07095962 0,11107928 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07095962 0,11100705 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07095962 0,11093492 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07095962 0,11086289 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07095962 0,11079095 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07095962 0,1107191 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07095962 0,11064734 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07095962 0,11057568 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07095962 0,11050411 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07095962 0,11043263 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07095962 0,11036125 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07095962 0,11028995 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07095962 0,11021875 ! insulin secretion GO:0030073 23 13 0,000 0,07095962 0,11014764 ! actin filament polymerization GO:0030041 24 13 0,000 0,07095962 0,11007663 ! acrosome reaction GO:0007340 18 13 0,000 0,07095962 0,1100057 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,07361394 0,11404709 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,07361394 0,1139737 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07523055 0,11640174 ! response to metal ion GO:0010038 140 80 1,000 0,07523055 0,11632693 ! muscle cell differentiation GO:0042692 159 80 1,000 0,07523055 0,11625222 ! rRNA transcription GO:0009303 25 14 0,000 0,07620599 0,11768397 ! lactation GO:0007595 26 14 0,000 0,07620599 0,11760848 ! reproductive cellular process GO:0048610 20 14 0,000 0,07620599 0,11753309 ! tRNA modification GO:0006400 20 14 0,000 0,07620599 0,1174578 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07620599 0,1173826 ! water transport GO:0006833 21 14 0,000 0,07620599 0,1173075 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07620599 0,1172325 ! non-recombinational repair GO:0000726 25 14 0,000 0,07620599 0,11715759 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07620599 0,11708277 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07620599 0,11700806 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07620599 0,11693343 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07620599 0,11685891 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07620599 0,11678447 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07620599 0,11671014 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07620599 0,11663589 ! regulation of heart rate GO:0002027 24 14 0,000 0,07620599 0,11656174 ! organic alcohol transport GO:0015850 29 14 0,000 0,07620599 0,11648769 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07620599 0,11641373 ! embryo implantation GO:0007566 30 14 0,000 0,07620599 0,11633986 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07620599 0,11626609 ! L-amino acid transport GO:0015807 30 14 0,000 0,07620599 0,11619241 ! bone mineralization GO:0030282 17 14 0,000 0,07620599 0,11611882 ! stem cell development GO:0048864 43 14 0,000 0,07620599 0,11604533 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07620599 0,11597193 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07620599 0,11589862 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07620599 0,11582541 ! cerebellum development GO:0021549 21 14 0,000 0,07620599 0,11575229 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07620599 0,11567926 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07620599 0,11560632 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07620599 0,11553347 ! cofactor transport GO:0051181 26 14 0,000 0,07620599 0,11546072 ! NADP metabolic process GO:0006739 24 14 0,000 0,07620599 0,11538806 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07620599 0,11531549 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07620599 0,11524301 ! intestinal absorption GO:0050892 25 14 0,000 0,07620599 0,11517062 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07620599 0,11509832 ! oxygen transport GO:0015671 21 14 0,000 0,07620599 0,11502611 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07620599 0,114954 ! male genitalia development GO:0030539 24 14 0,000 0,07620599 0,11488197 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07620599 0,11481003 ! regulation of axon extension GO:0030516 37 14 0,000 0,07620599 0,11473819 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07620599 0,11466643 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,07685847 0,11557592 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,07685847 0,11550373 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07849752 0,11789328 ! response to drug GO:0042493 143 82 1,000 0,07849752 0,11781973 ! response to nutrient GO:0007584 125 82 1,000 0,07849752 0,11774628 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,07849752 0,11767292 ! response to oxygen levels GO:0070482 176 83 1,000 0,08014752 0,12007157 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08014752 0,11999685 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08142292 0,12183056 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08142292 0,12175484 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,08142292 0,12167922 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,08142292 0,12160368 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08142292 0,12152825 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08142292 0,12145291 ! copper ion transport GO:0006825 20 15 0,000 0,08142292 0,12137766 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08142292 0,1213025 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08142292 0,12122744 ! sulfate transport GO:0008272 23 15 0,000 0,08142292 0,12115247 ! response to cAMP GO:0051591 22 15 0,000 0,08142292 0,12107759 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08142292 0,1210028 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08142292 0,12092811 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08142292 0,12085351 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08142292 0,120779 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08142292 0,12070458 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08142292 0,12063026 ! pituitary gland development GO:0021983 29 15 0,000 0,08142292 0,12055602 ! vesicle coating GO:0006901 33 15 0,000 0,08142292 0,12048188 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08142292 0,12040783 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08142292 0,12033387 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08142292 0,12026 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08142292 0,12018622 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08142292 0,12011253 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08142292 0,12003893 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08142292 0,11996542 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08142292 0,11989201 ! histone deacetylation GO:0016575 20 15 0,000 0,08142292 0,11981868 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08142292 0,11974544 ! tissue regeneration GO:0042246 26 15 0,000 0,08142292 0,11967229 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08142292 0,11959923 ! water homeostasis GO:0030104 27 15 0,000 0,08142292 0,11952626 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08142292 0,11945338 ! muscle maintenance GO:0046716 26 15 0,000 0,08142292 0,11938058 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08142292 0,11930788 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08142292 0,11923526 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08142292 0,11916274 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08142292 0,1190903 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08142292 0,11901794 ! cell killing GO:0001906 29 15 0,000 0,08142292 0,11894568 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08142292 0,11887351 ! detection of bacterium GO:0016045 18 15 0,000 0,08142292 0,11880142 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08142292 0,11872942 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08142292 0,1186575 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08142292 0,11858568 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08142292 0,11851394 ! peptide hormone processing GO:0016486 23 15 0,000 0,08142292 0,11844228 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,0818083 0,11893099 ! response to unfolded protein GO:0006986 131 85 1,000 0,08347969 0,12128753 ! amine biosynthetic process GO:0009309 138 86 1,000 0,08516152 0,12365638 ! response to inorganic substance GO:0010035 153 86 1,000 0,08516152 0,1235818 ! tube morphogenesis GO:0035239 176 86 1,000 0,08516152 0,12350731 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08661055 0,12553312 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08661055 0,12545754 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08661055 0,12538206 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08661055 0,12530666 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08661055 0,12523136 ! bone remodeling GO:0046849 27 16 0,000 0,08661055 0,12515614 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08661055 0,12508102 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08661055 0,12500599 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08661055 0,12493104 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08661055 0,12485619 ! startle response GO:0001964 28 16 0,000 0,08661055 0,12478142 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08661055 0,12470675 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08661055 0,12463216 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08661055 0,12455767 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08661055 0,12448326 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08661055 0,12440894 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08661055 0,12433471 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08661055 0,12426057 ! response to osmotic stress GO:0006970 25 16 0,000 0,08661055 0,12418652 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08661055 0,12411255 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08661055 0,12403868 ! fructose metabolic process GO:0006000 25 16 0,000 0,08661055 0,12396489 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08661055 0,12389119 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08661055 0,12381758 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08661055 0,12374405 ! axon cargo transport GO:0008088 43 16 0,000 0,08661055 0,12367061 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08661055 0,12359726 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08661055 0,12352399 ! DNA replication initiation GO:0006270 27 16 0,000 0,08661055 0,12345082 ! neuron recognition GO:0008038 35 16 0,000 0,08661055 0,12337773 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08661055 0,12330472 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08661055 0,1232318 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08661055 0,12315897 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08661055 0,12308623 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08661055 0,12301357 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08661055 0,12294099 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08661055 0,1228685 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08661055 0,1227961 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08661055 0,12272378 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08661055 0,12265155 ! defense response to virus GO:0051607 37 16 0,000 0,08661055 0,1225794 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08685362 0,12285115 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,08685362 0,12277896 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,09026793 0,12753062 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09176905 0,12957532 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09176905 0,12949932 ! metencephalon development GO:0022037 30 17 0,000 0,09176905 0,12942342 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09176905 0,1293476 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,09176905 0,12927187 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09176905 0,12919622 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09176905 0,12912067 ! endothelial cell migration GO:0043542 28 17 0,000 0,09176905 0,12904521 ! inositol metabolic process GO:0006020 28 17 0,000 0,09176905 0,12896983 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09176905 0,12889454 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09176905 0,12881934 ! glial cell development GO:0021782 27 17 0,000 0,09176905 0,12874423 ! limbic system development GO:0021761 36 17 0,000 0,09176905 0,1286692 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09176905 0,12859426 ! adult walking behavior GO:0007628 33 17 0,000 0,09176905 0,12851941 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09176905 0,12844465 ! heart looping GO:0001947 30 17 0,000 0,09176905 0,12836997 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09176905 0,12829538 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09176905 0,12822087 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09176905 0,12814646 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,09176905 0,12807213 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09176905 0,12799788 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09176905 0,12792372 ! glycine metabolic process GO:0006544 28 17 0,000 0,09176905 0,12784965 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09176905 0,12777566 ! NAD metabolic process GO:0019674 29 17 0,000 0,09176905 0,12770176 ! membrane budding GO:0006900 37 17 0,000 0,09176905 0,12762795 ! DNA integration GO:0015074 29 17 0,000 0,09176905 0,12755422 ! regulation of protein binding GO:0043393 33 17 0,000 0,09176905 0,12748057 ! genitalia development GO:0048806 30 17 0,000 0,09176905 0,12740701 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09176905 0,12733353 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09176905 0,12726014 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09176905 0,12718684 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09176905 0,12711361 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09176905 0,12704048 ! steroid catabolic process GO:0006706 31 17 0,000 0,09176905 0,12696742 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09176905 0,12689445 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09176905 0,12682157 ! gas transport GO:0015669 25 17 0,000 0,09176905 0,12674876 ! organic cation transport GO:0015695 31 17 0,000 0,09176905 0,12667604 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09176905 0,12660341 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,09176905 0,12653086 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09176905 0,12645839 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09176905 0,126386 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09176905 0,1263137 ! ossification GO:0001503 188 90 1,000 0,09198983 0,12654518 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09198983 0,12647287 ! bone development GO:0060348 189 91 1,000 0,09372133 0,12877985 ! response to protein stimulus GO:0051789 149 91 1,000 0,09372133 0,12870634 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0968986 0,13299374 ! neuron maturation GO:0042551 42 18 0,000 0,0968986 0,13291792 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,0968986 0,13284218 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0968986 0,13276653 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0968986 0,13269097 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0968986 0,13261549 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0968986 0,1325401 ! memory GO:0007613 31 18 0,000 0,0968986 0,13246479 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0968986 0,13238957 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0968986 0,13231443 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0968986 0,13223938 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0968986 0,13216442 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0968986 0,13208953 ! response to retinoic acid GO:0032526 26 18 0,000 0,0968986 0,13201474 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,0968986 0,13194003 ! response to fungus GO:0009620 21 18 0,000 0,0968986 0,1318654 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0968986 0,13179086 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0968986 0,1317164 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0968986 0,13164203 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0968986 0,13156774 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0968986 0,13149353 ! vitamin transport GO:0051180 27 18 0,000 0,0968986 0,13141941 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0968986 0,13134537 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0968986 0,13127141 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0968986 0,13119754 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0968986 0,13112375 ! nerve development GO:0021675 28 18 0,000 0,0968986 0,13105004 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0968986 0,13097642 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,09721249 0,13132693 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,09721249 0,13125323 ! regulation of membrane potential GO:0042391 164 93 1,000 0,09721249 0,13117962 ! female pregnancy GO:0007565 164 94 1,000 0,09897184 0,13347884 ! forebrain development GO:0030900 188 95 1,000 0,10074016 0,13578758 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,10074016 0,13571155 ! protein secretion GO:0009306 39 19 0,000 0,10199934 0,13733095 ! positive regulation of translation GO:0045727 30 19 0,000 0,10199934 0,13725415 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10199934 0,13717743 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10199934 0,13710079 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10199934 0,13702424 ! skin development GO:0043588 36 19 0,000 0,10199934 0,13694778 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10199934 0,1368714 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10199934 0,1367951 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10199934 0,13671889 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10199934 0,13664277 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10199934 0,13656673 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10199934 0,13649078 ! cerebral cortex development GO:0021987 36 19 0,000 0,10199934 0,1364149 ! pigmentation during development GO:0048066 41 19 0,000 0,10199934 0,13633912 ! response to vitamin A GO:0033189 27 19 0,000 0,10199934 0,13626342 ! heme metabolic process GO:0042168 36 19 0,000 0,10199934 0,1361878 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10199934 0,13611226 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10199934 0,13603681 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10199934 0,13596145 ! peptide cross-linking GO:0018149 37 19 0,000 0,10199934 0,13588616 ! protein export from nucleus GO:0006611 36 19 0,000 0,10199934 0,13581096 ! heart process GO:0003015 30 19 0,000 0,10199934 0,13573585 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10199934 0,13566081 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10199934 0,13558586 ! visual learning GO:0008542 36 19 0,000 0,10199934 0,135511 ! cellular pigmentation GO:0033059 36 19 0,000 0,10199934 0,13543621 ! G1 phase GO:0051318 40 19 0,000 0,10199934 0,13536151 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10199934 0,13528689 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10199934 0,13521235 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10199934 0,13513789 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10199934 0,13506352 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10199934 0,13498923 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10199934 0,13491502 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10199934 0,13484089 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10199934 0,13476684 ! cilium assembly GO:0042384 37 19 0,000 0,10199934 0,13469287 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10199934 0,13461899 ! detection of stimulus GO:0051606 151 96 1,000 0,10251729 0,1352284 ! protein ubiquitination GO:0016567 217 97 1,000 0,10430307 0,1375086 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,10609736 0,13979751 GO:0016054|organic acid catabolic process, ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10707144 0,14100377 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10707144 0,14092664 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10707144 0,14084958 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10707144 0,14077262 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10707144 0,14069573 ! response to vitamin GO:0033273 31 20 0,000 0,10707144 0,14061894 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10707144 0,14054222 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10707144 0,14046559 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10707144 0,14038904 ! response to alkaloid GO:0043279 38 20 0,000 0,10707144 0,14031258 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10707144 0,14023619 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10707144 0,1401599 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10707144 0,14008368 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10707144 0,14000755 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10707144 0,1399315 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10707144 0,13985553 ! body fluid secretion GO:0007589 31 20 0,000 0,10707144 0,13977965 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10707144 0,13970384 ! peptide secretion GO:0002790 35 20 0,000 0,10707144 0,13962812 ! stem cell differentiation GO:0048863 53 20 0,000 0,10707144 0,13955249 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10707144 0,13947693 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10707144 0,13940146 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10707144 0,13932606 ! sensory perception of pain GO:0019233 30 20 0,000 0,10707144 0,13925075 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10707144 0,13917552 ! diencephalon development GO:0021536 34 20 0,000 0,10707144 0,13910037 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10707144 0,1390253 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10707144 0,13895032 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10707144 0,13887541 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,10707144 0,13880059 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10707144 0,13872584 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10707144 0,13865118 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10707144 0,13857659 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10707144 0,13850209 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10707144 0,13842767 ! regulation of glucose import GO:0046324 29 20 0,000 0,10707144 0,13835332 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10707144 0,13827906 ! actin filament-based movement GO:0030048 43 20 0,000 0,10707144 0,13820488 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10707144 0,13813077 ! negative regulation of translation GO:0017148 29 20 0,000 0,10707144 0,13805675 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10707144 0,1379828 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,1079 0,13897613 ! regulation of cell killing GO:0031341 42 21 0,000 0,11211506 0,1443279 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11211506 0,14425072 ! hormone secretion GO:0046879 38 21 0,000 0,11211506 0,14417362 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11211506 0,1440966 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11211506 0,14401967 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11211506 0,14394282 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11211506 0,14386605 ! axis specification GO:0009798 38 21 0,000 0,11211506 0,14378936 ! ovarian follicle development GO:0001541 35 21 0,000 0,11211506 0,14371276 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11211506 0,14363623 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11211506 0,14355979 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11211506 0,14348343 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11211506 0,14340715 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11211506 0,14333095 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11211506 0,14325483 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11211506 0,14317879 ! cytolysis GO:0019835 24 21 0,000 0,11211506 0,14310283 ! vasodilation GO:0042311 39 21 0,000 0,11211506 0,14302696 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11211506 0,14295116 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11211506 0,14287545 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11211506 0,14279981 ! DNA modification GO:0006304 34 21 0,000 0,11211506 0,14272425 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,11211506 0,14264878 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11211506 0,14257338 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11211506 0,14249807 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11211506 0,14242283 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11211506 0,14234767 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11211506 0,1422726 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11211506 0,1421976 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11211506 0,14212268 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11211506 0,14204784 ! collagen catabolic process GO:0030574 28 21 0,000 0,11211506 0,14197307 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11211506 0,14189839 ! gut development GO:0048565 39 21 0,000 0,11211506 0,14182379 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11713036 0,1480902 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11713036 0,14801242 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11713036 0,14793472 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11713036 0,14785711 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11713036 0,14777958 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,11713036 0,14770212 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11713036 0,14762475 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11713036 0,14754746 ! regeneration GO:0031099 41 22 0,000 0,11713036 0,14747025 ! keratinization GO:0031424 28 22 0,000 0,11713036 0,14739312 ! sensory perception of taste GO:0050909 28 22 0,000 0,11713036 0,14731607 ! vacuolar transport GO:0007034 36 22 0,000 0,11713036 0,14723911 ! lysosome organization GO:0007040 41 22 0,000 0,11713036 0,14716222 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11713036 0,14708541 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11713036 0,14700869 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11713036 0,14693204 ! fucose metabolic process GO:0006004 39 22 0,000 0,11713036 0,14685547 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11713036 0,14677898 ! renal system process GO:0003014 41 22 0,000 0,11713036 0,14670258 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11713036 0,14662625 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11713036 0,14655 ! sarcomere organization GO:0045214 30 22 0,000 0,11713036 0,14647383 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,11713036 0,14639774 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11713036 0,14632173 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11713036 0,1462458 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,11713036 0,14616994 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11713036 0,14609417 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,1221175 0,1522356 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,1221175 0,15215676 ! gluconeogenesis GO:0006094 33 23 0,000 0,1221175 0,152078 ! viral genome replication GO:0019079 41 23 0,000 0,1221175 0,15199933 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,1221175 0,15192073 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,1221175 0,15184222 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,1221175 0,15176379 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,1221175 0,15168544 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,1221175 0,15160717 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,1221175 0,15152898 ! visual behavior GO:0007632 42 23 0,000 0,1221175 0,15145088 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,1221175 0,15137285 ! response to ethanol GO:0045471 46 23 0,000 0,1221175 0,1512949 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,1221175 0,15121703 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,1221175 0,15113925 ! peroxisome organization GO:0007031 37 23 0,000 0,1221175 0,15106154 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,1221175 0,15098392 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,1221175 0,15090637 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,1221175 0,1508289 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,1221175 0,15075151 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,1221175 0,1506742 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,1221175 0,15059698 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,1221175 0,15051983 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,1221175 0,15044275 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,1221175 0,15036576 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,1221175 0,15028885 ! fatty acid transport GO:0015908 44 23 0,000 0,1221175 0,15021201 ! platelet activation GO:0030168 37 23 0,000 0,1221175 0,15013526 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,1221175 0,15005858 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,1221175 0,14998198 ! hormone transport GO:0009914 40 23 0,000 0,1221175 0,14990546 ! cell-cell recognition GO:0009988 25 23 0,000 0,1221175 0,14982902 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,1221175 0,14975265 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,1221175 0,14967636 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,1221175 0,14960015 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,1221175 0,14952402 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,12707663 0,15551697 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12707663 0,15543791 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12707663 0,15535892 ! vesicle docking GO:0048278 47 24 0,000 0,12707663 0,15528002 ! spinal cord development GO:0021510 47 24 0,000 0,12707663 0,1552012 ! vacuole organization GO:0007033 43 24 0,000 0,12707663 0,15512246 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,12707663 0,15504379 ! digestive system process GO:0022600 39 24 0,000 0,12707663 0,15496521 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12707663 0,15488671 ! regulation of behavior GO:0050795 43 24 0,000 0,12707663 0,15480829 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,12707663 0,15472994 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,12707663 0,15465168 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12707663 0,15457349 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12707663 0,15449538 ! membrane depolarization GO:0051899 39 24 0,000 0,12707663 0,15441735 ! pallium development GO:0021543 49 24 0,000 0,12707663 0,15433941 ! pentose metabolic process GO:0019321 35 24 0,000 0,12707663 0,15426154 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,12707663 0,15418374 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12707663 0,15410603 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12707663 0,15402839 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12707663 0,15395084 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12707663 0,15387336 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12707663 0,15379596 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12707663 0,15371863 ! regulation of amine transport GO:0051952 40 24 0,000 0,12707663 0,15364139 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13200791 0,15952337 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,13200791 0,15944328 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13200791 0,15936328 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13200791 0,15928336 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13200791 0,15920352 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,13200791 0,15912376 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13200791 0,15904408 ! chromosome condensation GO:0030261 45 25 0,000 0,13200791 0,15896447 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13200791 0,15888495 ! neural crest cell development GO:0014032 54 25 0,000 0,13200791 0,15880551 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13200791 0,15872615 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13200791 0,15864686 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13200791 0,15856766 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13200791 0,15848853 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13200791 0,15840949 ! immunoglobulin production GO:0002377 55 25 0,000 0,13200791 0,15833052 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13200791 0,15825163 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13200791 0,15817282 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13200791 0,15809409 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13200791 0,15801543 ! telomere organization GO:0032200 43 25 0,000 0,13200791 0,15793686 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13200791 0,15785836 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13200791 0,15777994 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13691149 0,1635596 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13691149 0,16347843 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13691149 0,16339734 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13691149 0,16331633 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13691149 0,1632354 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13691149 0,16315455 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13691149 0,16307378 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13691149 0,16299309 ! tube lumen formation GO:0035148 50 26 0,000 0,13691149 0,16291248 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13691149 0,16283195 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13691149 0,1627515 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,13691149 0,16267113 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13691149 0,16259084 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13691149 0,16251063 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13691149 0,16243049 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13691149 0,16235044 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,13691149 0,16227046 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13691149 0,16219057 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13691149 0,16211075 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13691149 0,16203101 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13691149 0,16195135 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13691149 0,16187177 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13691149 0,16179226 ! iron ion transport GO:0006826 59 27 0,000 0,14178753 0,16747217 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14178753 0,16738999 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14178753 0,1673079 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14178753 0,16722589 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14178753 0,16714395 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14178753 0,1670621 ! autophagy GO:0006914 41 27 0,000 0,14178753 0,16698033 ! response to toxin GO:0009636 47 27 0,000 0,14178753 0,16689863 ! primary neural tube formation GO:0014020 51 27 0,000 0,14178753 0,16681702 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14178753 0,16673549 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14178753 0,16665403 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,14178753 0,16657266 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14178753 0,16649136 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14178753 0,16641015 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14178753 0,16632901 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14663619 0,17193308 ! circadian rhythm GO:0007623 50 28 0,000 0,14663619 0,17184933 ! dendrite development GO:0016358 59 28 0,000 0,14663619 0,17176567 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14663619 0,17168208 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14663619 0,17159858 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14663619 0,17151516 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14663619 0,17143182 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14663619 0,17134856 ! synaptogenesis GO:0007416 42 28 0,000 0,14663619 0,17126538 ! lipid oxidation GO:0034440 43 28 0,000 0,14663619 0,17118228 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14663619 0,17109926 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14663619 0,17101632 ! translational initiation GO:0006413 65 29 0,000 0,15145762 0,17655379 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15145762 0,17646829 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,15145762 0,17638288 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15145762 0,17629754 ! catechol metabolic process GO:0009712 54 29 0,000 0,15145762 0,17621229 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15145762 0,17612713 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15145762 0,17604204 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15145762 0,17595704 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15145762 0,17587212 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15145762 0,17578728 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15145762 0,17570252 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15145762 0,17561784 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15145762 0,17553325 ! regulation of coagulation GO:0050818 46 29 0,000 0,15145762 0,17544874 ! phenol metabolic process GO:0018958 55 30 0,000 0,15625196 0,18091541 ! zinc ion transport GO:0006829 45 30 0,000 0,15625196 0,18082839 ! membrane docking GO:0022406 61 30 0,000 0,15625196 0,18074145 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,15625196 0,1806546 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15625196 0,18056783 ! acute-phase response GO:0006953 49 30 0,000 0,15625196 0,18048114 ! myofibril assembly GO:0030239 47 30 0,000 0,15625196 0,18039454 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15625196 0,18030802 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,15625196 0,18022158 ! phospholipid transport GO:0015914 51 30 0,000 0,15625196 0,18013523 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15625196 0,18004895 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15625196 0,17996276 ! eye morphogenesis GO:0048592 60 30 0,000 0,15625196 0,17987666 ! response to heat GO:0009408 50 30 0,000 0,15625196 0,17979063 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16101937 0,18518767 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16101937 0,18509919 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16101937 0,1850108 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16101937 0,18492249 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16101937 0,18483426 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16101937 0,18474612 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16101937 0,18465806 ! ovulation cycle process GO:0022602 49 31 0,000 0,16101937 0,18457009 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16101937 0,1844822 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16101937 0,18439439 ! peptide transport GO:0015833 55 31 0,000 0,16101937 0,18430667 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16101937 0,18421903 ! iron ion homeostasis GO:0055072 54 31 0,000 0,16101937 0,18413147 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16101937 0,184044 ! natural killer cell activation GO:0030101 45 31 0,000 0,16101937 0,18395661 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16101937 0,1838693 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16101937 0,18378207 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16101937 0,18369493 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16101937 0,18360787 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16576001 0,18892401 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16576001 0,18883455 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16576001 0,18874519 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16576001 0,1886559 ! cholesterol transport GO:0030301 56 32 0,000 0,16576001 0,1885667 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16576001 0,18847759 ! spliceosome assembly GO:0000245 67 32 0,000 0,16576001 0,18838856 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16576001 0,18829961 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,16576001 0,18821075 ! muscle cell development GO:0055001 49 32 0,000 0,16576001 0,18812197 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16576001 0,18803328 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,16576001 0,18794466 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,16576001 0,18785614 ! ovulation cycle GO:0042698 51 32 0,000 0,16576001 0,18776769 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16576001 0,18767933 ! hindbrain development GO:0030902 61 32 0,000 0,16576001 0,18759105 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,16576001 0,18750286 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16576001 0,18741474 ! gene silencing GO:0016458 65 32 0,000 0,16576001 0,18732672 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17047401 0,1925636 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17047401 0,19247324 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17047401 0,19238296 ! sterol transport GO:0015918 57 33 0,000 0,17047401 0,19229277 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,17047401 0,19220266 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17047401 0,19211263 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17047401 0,19202269 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17047401 0,19193284 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,17516153 0,19711817 ! glial cell differentiation GO:0010001 63 34 0,000 0,17516153 0,19702602 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17516153 0,19693395 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17516153 0,19684197 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17516153 0,19675007 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,17516153 0,19665826 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17516153 0,19656653 ! mismatch repair GO:0006298 46 34 0,000 0,17516153 0,19647489 ! spermatid development GO:0007286 63 34 0,000 0,17516153 0,19638334 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17516153 0,19629187 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17516153 0,19620049 ! regulation of muscle development GO:0048634 70 35 0,000 0,17982272 0,20132781 ! negative regulation of secretion GO:0051048 63 35 0,000 0,17982272 0,20123417 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,17982272 0,20114062 ! odontogenesis GO:0042476 66 35 0,000 0,17982272 0,20104715 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,17982272 0,20095377 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,17982272 0,20086048 ! cytokine production GO:0001816 59 35 0,000 0,17982272 0,20076727 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17982272 0,20067415 ! neural tube formation GO:0001841 67 35 0,000 0,17982272 0,20058112 ! vesicle localization GO:0051648 64 35 0,000 0,17982272 0,20048817 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,18445772 0,20556058 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18445772 0,20546541 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18445772 0,20537033 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18445772 0,20527534 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18445772 0,20518044 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18445772 0,20508562 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18445772 0,20499089 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18445772 0,20489625 ! aerobic respiration GO:0009060 55 36 0,000 0,18445772 0,2048017 ! embryonic organ development GO:0048568 57 36 0,000 0,18445772 0,20470723 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18445772 0,20461286 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18906669 0,20962878 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,18906669 0,20953222 ! sister chromatid segregation GO:0000819 58 37 0,000 0,18906669 0,20943575 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18906669 0,20933937 ! organic anion transport GO:0015711 68 37 0,000 0,18906669 0,20924308 ! tissue remodeling GO:0048771 76 37 0,000 0,18906669 0,20914687 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18906669 0,20905076 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,18906669 0,20895473 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18906669 0,20885879 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,18906669 0,20876294 ! spermatid differentiation GO:0048515 66 37 0,000 0,18906669 0,20866718 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19364975 0,21362738 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19364975 0,21352947 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19364975 0,21343166 ! lipid homeostasis GO:0055088 67 38 0,000 0,19364975 0,21333393 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19364975 0,2132363 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19364975 0,21313875 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19364975 0,21304129 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19364975 0,21294392 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,19364975 0,21284664 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,19364975 0,21274945 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,19820707 0,21765687 ! learning GO:0007612 77 39 0,000 0,19820707 0,21755758 ! organic ether metabolic process GO:0018904 55 39 0,000 0,19820707 0,21745837 ! ion transmembrane transport GO:0034220 66 39 0,000 0,19820707 0,21735926 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,19820707 0,21726023 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,19820707 0,2171613 ! RNA modification GO:0009451 57 39 0,000 0,19820707 0,21706245 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,19820707 0,2169637 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,20273878 0,22182333 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20273878 0,2217225 ! feeding behavior GO:0007631 59 40 0,000 0,20273878 0,22162177 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,20273878 0,22152112 ! mesenchymal cell development GO:0014031 87 40 0,000 0,20273878 0,22142057 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20273878 0,2213201 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20724503 0,22613675 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,20724503 0,22603424 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,20724503 0,22593183 ! gliogenesis GO:0042063 88 41 0,000 0,20724503 0,2258295 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,20724503 0,22572727 ! polyol metabolic process GO:0019751 66 41 0,000 0,20724503 0,22562513 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,20724503 0,22552308 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,21172595 0,23029505 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,21172595 0,23019098 ! regulation of tube size GO:0035150 71 42 0,000 0,21172595 0,23008701 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21172595 0,22998314 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21172595 0,22987935 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21172595 0,22977566 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21172595 0,22967207 ! neuron migration GO:0001764 79 42 0,000 0,21172595 0,22956857 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21172595 0,22946516 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,2161817 0,23418873 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,2161817 0,23408334 ! glucose transport GO:0015758 65 43 0,000 0,2161817 0,23397804 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,2161817 0,23387283 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,2161817 0,23376772 ! neural tube development GO:0021915 77 43 0,000 0,2161817 0,2336627 ! striated muscle contraction GO:0006941 77 43 0,000 0,2161817 0,23355778 ! phagocytosis GO:0006909 90 43 0,000 0,2161817 0,23345295 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,2161817 0,23334822 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22061241 0,23802397 ! hexose transport GO:0008645 67 44 0,000 0,22061241 0,23791728 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,22061241 0,23781069 ! biopolymer methylation GO:0043414 84 44 0,000 0,22061241 0,23770419 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22061241 0,23759779 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22501822 0,24223438 ! glycolysis GO:0006096 65 45 0,000 0,22501822 0,24212604 ! leukocyte migration GO:0050900 68 45 0,000 0,22501822 0,24201781 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22501822 0,24190967 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22501822 0,24180162 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22501822 0,24169368 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22501822 0,24158583 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22501822 0,24147807 ! cell growth GO:0016049 84 45 0,000 0,22501822 0,24137041 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,22939927 0,24596018 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,22939927 0,24585062 ! pigmentation GO:0043473 100 46 0,000 0,22939927 0,24574116 ! positive regulation of defense response GO:0031349 76 47 0,000 0,23375569 0,25029648 ! response to calcium ion GO:0051592 81 47 0,000 0,23375569 0,25018514 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,23375569 0,2500739 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,23375569 0,24996276 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23375569 0,24985171 ! JNK cascade GO:0007254 91 47 0,000 0,23375569 0,24974076 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,23375569 0,24962992 ! methylation GO:0032259 90 47 0,000 0,23375569 0,24951917 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,23808764 0,25403054 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,23808764 0,25391793 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,23808764 0,25380543 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,23808764 0,25369303 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24239523 0,25816863 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24239523 0,25805439 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24239523 0,25794026 ! regulation of ion transport GO:0043269 77 49 0,000 0,24239523 0,25782623 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,24239523 0,2577123 ! peptide metabolic process GO:0006518 76 49 0,000 0,24239523 0,25759847 ! response to temperature stimulus GO:0009266 76 49 0,000 0,24239523 0,25748474 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24239523 0,25737111 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24239523 0,25725758 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24239523 0,25714415 ! neuromuscular process GO:0050905 99 50 0,000 0,24667862 0,26157283 ! regulation of ossification GO:0030278 117 50 0,000 0,24667862 0,2614576 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,24667862 0,26134247 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,24667862 0,26122745 ! excretion GO:0007588 83 51 0,000 0,25093793 0,26562105 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,25093793 0,26550424 ! chromatin remodeling GO:0006338 109 51 0,000 0,25093793 0,26538754 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,25093793 0,26527094 ! regulation of cell shape GO:0008360 125 51 0,000 0,25093793 0,26515444 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,25517329 0,26951139 ! amino acid activation GO:0043038 92 52 0,000 0,25517329 0,26939313 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,25517329 0,26927498 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,25938485 0,27359928 ! RNA catabolic process GO:0006401 93 53 0,000 0,25938485 0,27347939 ! regulation of translational initiation GO:0006446 82 53 0,000 0,25938485 0,2733596 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,25938485 0,27323991 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,25938485 0,27312033 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,25938485 0,27300086 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,26357274 0,27728728 ! cell recognition GO:0008037 85 54 0,000 0,26357274 0,27716609 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26357274 0,277045 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26357274 0,27692402 ! chloride transport GO:0006821 90 55 0,000 0,26773708 0,28117653 ! glucose catabolic process GO:0006007 82 55 0,000 0,26773708 0,28105385 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,26773708 0,28093128 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,26773708 0,28080881 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,26773708 0,28068646 ! RNA elongation GO:0006354 79 55 0,000 0,26773708 0,28056421 ! nuclear export GO:0051168 97 55 0,000 0,26773708 0,28044206 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27187801 0,28465557 ! sensory perception of smell GO:0007608 80 56 0,000 0,27187801 0,28453175 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27187801 0,28440804 ! proton transport GO:0015992 94 56 0,000 0,27187801 0,28428444 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,27187801 0,28416095 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,27599567 0,28833937 ! hydrogen transport GO:0006818 97 58 0,000 0,28009017 0,29248999 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,28009017 0,2923631 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28009017 0,29223632 ! adult behavior GO:0030534 99 58 0,000 0,28009017 0,29210964 ! positive regulation of secretion GO:0051047 95 59 0,000 0,28416165 0,29622744 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28416165 0,29609915 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28416165 0,29597097 GO:0032313|regulation of Rab GTPase activity, ! nucleoside metabolic process GO:0009116 81 60 0,000 0,28821024 0,30005791 ! regulation of heart contraction GO:0008016 110 60 0,000 0,28821024 0,29992813 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29223607 0,30398615 ! tRNA processing GO:0008033 89 61 0,000 0,29223607 0,30385479 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29223607 0,30372353 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29623926 0,30775114 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,29623926 0,30761832 ! regulation of mitosis GO:0007088 105 63 0,000 0,30021994 0,31161741 GO:0051783|regulation of nuclear division, ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,30417823 0,31558983 ! cell redox homeostasis GO:0045454 102 64 0,000 0,30417823 0,3154538 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,30417823 0,31531789 ! single fertilization GO:0007338 75 64 0,000 0,30417823 0,31518209 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30811427 0,31912309 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,30811427 0,31898577 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,30811427 0,31884857 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31202817 0,32276001 ! secondary metabolic process GO:0019748 116 66 0,000 0,31202817 0,3226213 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,31592006 0,32650501 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,31592006 0,32636482 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,31592006 0,32622475 ! hexose catabolic process GO:0019320 104 67 0,000 0,31592006 0,3260848 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,31592006 0,32594497 ! adaptive immune response GO:0002250 119 67 0,000 0,31592006 0,32580526 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,31592006 0,32566567 ! amino acid transport GO:0006865 125 68 0,000 0,31979006 0,32951387 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,31979006 0,32937281 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,3236383 0,33319373 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,3236383 0,33305122 ! antigen processing and presentation GO:0019882 104 69 0,000 0,3236383 0,33290883 ! appendage morphogenesis GO:0035107 135 70 0,000 0,32746489 0,33670108 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,33126997 0,34046798 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,33126997 0,3403226 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,33126997 0,34017735 ! regulation of immune effector process GO:0002697 137 71 0,000 0,33126997 0,34003223 ! acute inflammatory response GO:0002526 113 72 0,000 0,33505363 0,34376931 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,33505363 0,34362278 ! carbohydrate transport GO:0008643 110 72 0,000 0,33505363 0,34347637 ! regulation of blood pressure GO:0008217 125 73 0,000 0,33881602 0,34718541 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,33881602 0,34703761 ! fertilization GO:0009566 90 73 0,000 0,33881602 0,34688993 ! transition metal ion transport GO:0000041 126 74 0,000 0,34255724 0,35057113 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,34255724 0,35042208 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,34255724 0,35027315 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,34627742 0,35392671 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,34627742 0,35377642 ! rhythmic process GO:0048511 128 75 0,000 0,34627742 0,35362626 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,34997667 0,35725238 ! defense response to bacterium GO:0042742 89 76 0,000 0,34997667 0,35710087 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,34997667 0,3569495 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,34997667 0,35679825 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,35365511 0,36039567 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,35365511 0,36024309 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,35365511 0,36009064 ! blood coagulation GO:0007596 146 78 0,000 0,35731285 0,36366105 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,35731285 0,36350728 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,35731285 0,36335364 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36095002 0,36689723 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,36095002 0,36674229 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,36456672 0,37026067 ! inorganic anion transport GO:0015698 138 80 0,000 0,36456672 0,37010444 ! digestion GO:0007586 112 81 0,000 0,36816307 0,37359778 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,36816307 0,37344028 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,37173919 0,37690876 ! hemostasis GO:0007599 158 84 0,000 0,37883117 0,38393757 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,37883117 0,38377591 ! nucleosome assembly GO:0006334 122 85 0,000 0,38234726 0,38717488 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,38234726 0,38701199 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,38234726 0,38684925 GO:0002696|positive regulation of leukocyte activation, ! oxidative phosphorylation GO:0006119 133 86 0,000 0,38584356 0,39022262 ! chromatin assembly GO:0031497 124 86 0,000 0,38584356 0,39005866 ! alcohol catabolic process GO:0046164 130 86 0,000 0,38584356 0,38989484 ! amine transport GO:0015837 155 86 0,000 0,38584356 0,38973116 ! cellular respiration GO:0045333 135 88 0,000 0,39277725 0,39656822 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,39277725 0,39640187 ! regulation of neurological system process GO:0031644 148 88 0,000 0,39277725 0,39623567 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39277725 0,3960696 ! cellular defense response GO:0006968 114 89 0,000 0,39621486 0,39936864 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,39963312 0,40264543 ! sterol metabolic process GO:0016125 152 91 0,000 0,40303214 0,40590009 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,40303214 0,40573026 ! regulation of defense response GO:0031347 149 92 0,000 0,40641202 0,40896166 ! nucleosome organization GO:0034728 138 92 0,000 0,40641202 0,40879069 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,40641202 0,40861986 ! vitamin metabolic process GO:0006766 139 92 0,000 0,40641202 0,40844918 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,40977289 0,41165494 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,40977289 0,41148313 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,41311484 0,41466596 ! transcription initiation GO:0006352 153 94 0,000 0,41311484 0,41449303 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,4197424 0,42096716 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,4197424 0,42079176 ! positive regulation of immune response GO:0050778 156 96 0,000 0,4197424 0,4206165 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,42302823 0,42373269 ! hormone metabolic process GO:0042445 157 97 0,000 0,42302823 0,42355635 ! response to virus GO:0009615 160 98 0,000 0,42629555 0,42665021 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,42629555 0,42647281 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,42954449 0,42954449